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The map label for this gene is plsC [H]

Identifier: 120609606

GI number: 120609606

Start: 993726

End: 994463

Strand: Direct

Name: plsC [H]

Synonym: Aave_0912

Alternate gene names: 120609606

Gene position: 993726-994463 (Clockwise)

Preceding gene: 120609605

Following gene: 120609608

Centisome position: 18.56

GC content: 73.85

Gene sequence:

>738_bases
ATGCGCTCGCTGCGCGCGGTGGCGCGCCTGATGCGGCTCCTGGCGCACATCCTGGCGGGGCTGGCCACGGTGCTGCTGCG
CTTCCCCCGCATGGGGCCGGACGAGCAGCATGCGCGCGTGCAGGCCTGGTCGCGCATGCTGCTCGCGCACATCGGCATCG
ACCTGGAGGTACGGGGCACCCCGCCAGCGGCCGGGCCGGTGCTCCTGGTGGCCAACCACCTGTCCTGGCTCGACATCACC
GTCATGCACGCCGCGCGGCACTGCCGCTTCATCTCGAAATCGGACGTGGAGCGCTGGCCCGTCATCGGCCGGCTCGCCAC
GGCCGCGGGCACCCTCTACATCGAGCGCAACACGCGCCGCGATGCCATGCGCATCGTGCGCCTCATGCAGGAGGCGCTGG
CGCGCCGCGAGGTGCTGGGCGTGTTCCCCGAAGGAACGACGGGCGACGGCGCCGAGCTGCTGCCGTTCCATGCGAATCTC
CTGCAGGCGGCGGTGATGGCCGATGCGCCGGTGCAGCCCGTGGGCCTGCGCTTCATCGACCGCGCCACGGGCCGGCCCAG
CGCGGCCGCCCTCTACGTGGGCGACGACACCCTGGTGCACTCGCTCTGGCGCGTGCTGTGCGCCGACGGCCTGGTGGCCA
TCGTGCACTACGGGCCGCCCCAGCATGCAGCGGGCCGCGACCGGCGCGCGTGGGCGGAAGACCTCCGGCAGGCCGTGGAC
GCGCTGCGGCGGACCTGA

Upstream 100 bases:

>100_bases
TGCGCAGCCAGGGGCGGCACACGCCGTTCTCCGGCTACGAGCTGCCGGGCCGCGTGCGCTGGACGCTGGTGGGCGGCATC
GTCGCGTTCGAGCGCGTCTG

Downstream 100 bases:

>100_bases
ACGTTTTCCAGATGAGACAGAGCCTGCTGGCCTCCGCTGAAGGAGTGCTGCCTCGCGCTGTCCATGGTGGTGCTCGGCAG
CCTGTTCTTTCTCGCCAATG

Product: lyso-ornithine lipid acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MRSLRAVARLMRLLAHILAGLATVLLRFPRMGPDEQHARVQAWSRMLLAHIGIDLEVRGTPPAAGPVLLVANHLSWLDIT
VMHAARHCRFISKSDVERWPVIGRLATAAGTLYIERNTRRDAMRIVRLMQEALARREVLGVFPEGTTGDGAELLPFHANL
LQAAVMADAPVQPVGLRFIDRATGRPSAAALYVGDDTLVHSLWRVLCADGLVAIVHYGPPQHAAGRDRRAWAEDLRQAVD
ALRRT

Sequences:

>Translated_245_residues
MRSLRAVARLMRLLAHILAGLATVLLRFPRMGPDEQHARVQAWSRMLLAHIGIDLEVRGTPPAAGPVLLVANHLSWLDIT
VMHAARHCRFISKSDVERWPVIGRLATAAGTLYIERNTRRDAMRIVRLMQEALARREVLGVFPEGTTGDGAELLPFHANL
LQAAVMADAPVQPVGLRFIDRATGRPSAAALYVGDDTLVHSLWRVLCADGLVAIVHYGPPQHAAGRDRRAWAEDLRQAVD
ALRRT
>Mature_245_residues
MRSLRAVARLMRLLAHILAGLATVLLRFPRMGPDEQHARVQAWSRMLLAHIGIDLEVRGTPPAAGPVLLVANHLSWLDIT
VMHAARHCRFISKSDVERWPVIGRLATAAGTLYIERNTRRDAMRIVRLMQEALARREVLGVFPEGTTGDGAELLPFHANL
LQAAVMADAPVQPVGLRFIDRATGRPSAAALYVGDDTLVHSLWRVLCADGLVAIVHYGPPQHAAGRDRRAWAEDLRQAVD
ALRRT

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Drosophila melanogaster, GI281364648, Length=199, Percent_Identity=29.6482412060301, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582856, Length=199, Percent_Identity=29.6482412060301, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582854, Length=199, Percent_Identity=29.6482412060301, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27047; Mature: 27047

Theoretical pI: Translated: 11.22; Mature: 11.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLRAVARLMRLLAHILAGLATVLLRFPRMGPDEQHARVQAWSRMLLAHIGIDLEVRGT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCC
PPAAGPVLLVANHLSWLDITVMHAARHCRFISKSDVERWPVIGRLATAAGTLYIERNTRR
CCCCCCCEEHCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHEEEEEECCCHH
DAMRIVRLMQEALARREVLGVFPEGTTGDGAELLPFHANLLQAAVMADAPVQPVGLRFID
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RATGRPSAAALYVGDDTLVHSLWRVLCADGLVAIVHYGPPQHAAGRDRRAWAEDLRQAVD
HCCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
ALRRT
HHHCC
>Mature Secondary Structure
MRSLRAVARLMRLLAHILAGLATVLLRFPRMGPDEQHARVQAWSRMLLAHIGIDLEVRGT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCC
PPAAGPVLLVANHLSWLDITVMHAARHCRFISKSDVERWPVIGRLATAAGTLYIERNTRR
CCCCCCCEEHCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHEEEEEECCCHH
DAMRIVRLMQEALARREVLGVFPEGTTGDGAELLPFHANLLQAAVMADAPVQPVGLRFID
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RATGRPSAAALYVGDDTLVHSLWRVLCADGLVAIVHYGPPQHAAGRDRRAWAEDLRQAVD
HCCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
ALRRT
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8748025 [H]