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The map label for this gene is tcp [H]

Identifier: 120609525

GI number: 120609525

Start: 901967

End: 903652

Strand: Direct

Name: tcp [H]

Synonym: Aave_0831

Alternate gene names: 120609525

Gene position: 901967-903652 (Clockwise)

Preceding gene: 120609523

Following gene: 120609526

Centisome position: 16.85

GC content: 69.93

Gene sequence:

>1686_bases
ATGGATATTCTGGGACGCCTATCGATCCGCACGCGCCTGTACTTCGGCACGGTCTTTTCCCTGGTGCTGCTCATCGTGAT
CGGAGGGCTGGGATACCTGGCCCTCGACCGCACGCGCGATACGCTGCAGGTGCTTTTTTCCGAGCGGGTGCAGACGCTGA
CCGACATGGCCGACCTGCGCACGACGCTGGGGACGCTGCGCCGCACCGAGAAGGACATCATCCTCAACTTCAACAATTCC
GTCGAAGTAGCCGCCCAGCGCGAAACCTGGGCCAGGACCCTGGCCGCGCTGCGCAAGAGCCTCACGGCCGTGCGGCAGGT
GCAGGCAGGCGACCCGGCCTTCGCGGGCTCCATCGACAAGGCGCTGGCCGAGATCCAGCAGTACGAGGCCGGCATTTCCC
CGATCTTCGAGCAGATCGAGCGGGCGCAGCTCGACGGGGCCGGCGGCGCCGCCTATGCCGACCGCCTGAAGAGCCACATG
GAAACCACCGACCAGATCCTCGCGAGCCTCGCTCAGAGCGCCCGCGAGAACATGGAGGAGGCGCGGCAGGGCGTGGAGGC
GCGCACCGCCACCATGTCCGCGGTGATCGGCGGCGGGCTGGTGCTGGCCCTGGCGGTGCTGATCCCGCTCACCTTCTTCA
GCGTGCGCTCCATCACCGGTTCCCTGGCCCAGGCCCGCTCACTGGCCGAACGCATCGCCGGCGGGGACCTGTCGCATGAA
GTCCGGCCCGCCCAGATGGACGAGGTCGGCCAGCTCGTCGTGGCCATGGGGCGCATGCAGGACGCACTGCGCGGCCTGGT
GCGCCAGGTGCAGGACGCGTCCGGCAGCATCTCGACGGCCAGCACGGAGATCGCCTCGGGCAACCACGACCTGAGCCACC
GCACCGAGCAGACCGCCGCCAACCTGGAGGAAACCGCCTCGTCCATGGAAATGCTCGCCGGCACGGTGCAGCAGAGCACC
CAGTCCGCACGCCAGGCCAGCGACTTCGCGTCCACCGCGGCCCAGGTGGCGGCCAAGGGCGGCAGCGTGGTTTCGCAGGT
CGTGGACACCATGGGCCAGATCACCGACAGCTCGCGCAGGATCGCCGACATCACCGGCGTGATCGATTCCATCGCCTTCC
AGACCAACATCCTGGCGCTGAATGCCGCCGTCGAGGCGGCCCGCGCGGGCGAGCAGGGCCGCGGCTTCGCGGTGGTCGCG
GCCGAGGTGCGGACGCTGGCCCAGCGCTCGGCCTCGGCGGCCAAGGAAATCAAGGAGCTCATCGGCTCCTCGGTGGAGCG
CGTGGAAAGCGGCTCGCGCCTCGTGAGCCAGGCCGGCGCGACCATGACCGAGATCGTGGACAGCGTGCGCCGCGTCTCCG
AAATGATCACGGAGATCACCGCCTCGTCGGCCGAGCAGAGCGACAACATCGGCCAGATCAGCCAGTCCGTGAGCCAGCTC
GACCAGATGACCCAGCAGAACGCCGCGCTGGTGGAGCAGTCCACGGCCGCATCGGAGTCGCTGCGGGAGCAGGCGGTGCA
ACTGATTGGCGCCGTGCGCCGGTTCCGCCTCGACGACGGTCCGGCGGCGGACATCGCCCTGCAGGCACCGCCCCCGCCTG
GTGCCGCCTCCCTGGCGCCACGGCCCCTGGCCGCCGCCCTGCCCGGGCCGGTGTCCGGATTCGTGCGCCACGAACCTGCC
GCCTGA

Upstream 100 bases:

>100_bases
GTCGGGCCGTCCTATAGTGTGCGCCCCGGCGGCCCACGAGGCGGCAATGGGGTGGGCGCGGTTATTGCATGCGCCTTTGT
AACGTCTTGTAGGGGATGCC

Downstream 100 bases:

>100_bases
GCGGCACGCCCGACCGGACCGTGCCTGCGGTTTTCCCGGCAGTGGCCGGCGGAGCGTGATGGTAGGCTGCGGCTTTTGCC
CTGAAGCAACGAGCCATGAT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MDILGRLSIRTRLYFGTVFSLVLLIVIGGLGYLALDRTRDTLQVLFSERVQTLTDMADLRTTLGTLRRTEKDIILNFNNS
VEVAAQRETWARTLAALRKSLTAVRQVQAGDPAFAGSIDKALAEIQQYEAGISPIFEQIERAQLDGAGGAAYADRLKSHM
ETTDQILASLAQSARENMEEARQGVEARTATMSAVIGGGLVLALAVLIPLTFFSVRSITGSLAQARSLAERIAGGDLSHE
VRPAQMDEVGQLVVAMGRMQDALRGLVRQVQDASGSISTASTEIASGNHDLSHRTEQTAANLEETASSMEMLAGTVQQST
QSARQASDFASTAAQVAAKGGSVVSQVVDTMGQITDSSRRIADITGVIDSIAFQTNILALNAAVEAARAGEQGRGFAVVA
AEVRTLAQRSASAAKEIKELIGSSVERVESGSRLVSQAGATMTEIVDSVRRVSEMITEITASSAEQSDNIGQISQSVSQL
DQMTQQNAALVEQSTAASESLREQAVQLIGAVRRFRLDDGPAADIALQAPPPPGAASLAPRPLAAALPGPVSGFVRHEPA
A

Sequences:

>Translated_561_residues
MDILGRLSIRTRLYFGTVFSLVLLIVIGGLGYLALDRTRDTLQVLFSERVQTLTDMADLRTTLGTLRRTEKDIILNFNNS
VEVAAQRETWARTLAALRKSLTAVRQVQAGDPAFAGSIDKALAEIQQYEAGISPIFEQIERAQLDGAGGAAYADRLKSHM
ETTDQILASLAQSARENMEEARQGVEARTATMSAVIGGGLVLALAVLIPLTFFSVRSITGSLAQARSLAERIAGGDLSHE
VRPAQMDEVGQLVVAMGRMQDALRGLVRQVQDASGSISTASTEIASGNHDLSHRTEQTAANLEETASSMEMLAGTVQQST
QSARQASDFASTAAQVAAKGGSVVSQVVDTMGQITDSSRRIADITGVIDSIAFQTNILALNAAVEAARAGEQGRGFAVVA
AEVRTLAQRSASAAKEIKELIGSSVERVESGSRLVSQAGATMTEIVDSVRRVSEMITEITASSAEQSDNIGQISQSVSQL
DQMTQQNAALVEQSTAASESLREQAVQLIGAVRRFRLDDGPAADIALQAPPPPGAASLAPRPLAAALPGPVSGFVRHEPA
A
>Mature_561_residues
MDILGRLSIRTRLYFGTVFSLVLLIVIGGLGYLALDRTRDTLQVLFSERVQTLTDMADLRTTLGTLRRTEKDIILNFNNS
VEVAAQRETWARTLAALRKSLTAVRQVQAGDPAFAGSIDKALAEIQQYEAGISPIFEQIERAQLDGAGGAAYADRLKSHM
ETTDQILASLAQSARENMEEARQGVEARTATMSAVIGGGLVLALAVLIPLTFFSVRSITGSLAQARSLAERIAGGDLSHE
VRPAQMDEVGQLVVAMGRMQDALRGLVRQVQDASGSISTASTEIASGNHDLSHRTEQTAANLEETASSMEMLAGTVQQST
QSARQASDFASTAAQVAAKGGSVVSQVVDTMGQITDSSRRIADITGVIDSIAFQTNILALNAAVEAARAGEQGRGFAVVA
AEVRTLAQRSASAAKEIKELIGSSVERVESGSRLVSQAGATMTEIVDSVRRVSEMITEITASSAEQSDNIGQISQSVSQL
DQMTQQNAALVEQSTAASESLREQAVQLIGAVRRFRLDDGPAADIALQAPPPPGAASLAPRPLAAALPGPVSGFVRHEPA
A

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=321, Percent_Identity=52.6479750778816, Blast_Score=281, Evalue=7e-77,
Organism=Escherichia coli, GI2367378, Length=570, Percent_Identity=41.0526315789474, Blast_Score=281, Evalue=7e-77,
Organism=Escherichia coli, GI1788194, Length=348, Percent_Identity=48.5632183908046, Blast_Score=276, Evalue=3e-75,
Organism=Escherichia coli, GI1788195, Length=327, Percent_Identity=51.6819571865443, Blast_Score=271, Evalue=1e-73,
Organism=Escherichia coli, GI1789453, Length=316, Percent_Identity=40.8227848101266, Blast_Score=218, Evalue=7e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 59207; Mature: 59207

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILGRLSIRTRLYFGTVFSLVLLIVIGGLGYLALDRTRDTLQVLFSERVQTLTDMADLR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
TTLGTLRRTEKDIILNFNNSVEVAAQRETWARTLAALRKSLTAVRQVQAGDPAFAGSIDK
HHHHHHHHCCCCEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCHHHH
ALAEIQQYEAGISPIFEQIERAQLDGAGGAAYADRLKSHMETTDQILASLAQSARENMEE
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARQGVEARTATMSAVIGGGLVLALAVLIPLTFFSVRSITGSLAQARSLAERIAGGDLSHE
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VRPAQMDEVGQLVVAMGRMQDALRGLVRQVQDASGSISTASTEIASGNHDLSHRTEQTAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHH
NLEETASSMEMLAGTVQQSTQSARQASDFASTAAQVAAKGGSVVSQVVDTMGQITDSSRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHH
IADITGVIDSIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRTLAQRSASAAKEIKEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
IGSSVERVESGSRLVSQAGATMTEIVDSVRRVSEMITEITASSAEQSDNIGQISQSVSQL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
DQMTQQNAALVEQSTAASESLREQAVQLIGAVRRFRLDDGPAADIALQAPPPPGAASLAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCC
RPLAAALPGPVSGFVRHEPAA
CCHHHHCCCCHHHHCCCCCCC
>Mature Secondary Structure
MDILGRLSIRTRLYFGTVFSLVLLIVIGGLGYLALDRTRDTLQVLFSERVQTLTDMADLR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
TTLGTLRRTEKDIILNFNNSVEVAAQRETWARTLAALRKSLTAVRQVQAGDPAFAGSIDK
HHHHHHHHCCCCEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCHHHH
ALAEIQQYEAGISPIFEQIERAQLDGAGGAAYADRLKSHMETTDQILASLAQSARENMEE
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARQGVEARTATMSAVIGGGLVLALAVLIPLTFFSVRSITGSLAQARSLAERIAGGDLSHE
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VRPAQMDEVGQLVVAMGRMQDALRGLVRQVQDASGSISTASTEIASGNHDLSHRTEQTAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHH
NLEETASSMEMLAGTVQQSTQSARQASDFASTAAQVAAKGGSVVSQVVDTMGQITDSSRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHH
IADITGVIDSIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRTLAQRSASAAKEIKEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
IGSSVERVESGSRLVSQAGATMTEIVDSVRRVSEMITEITASSAEQSDNIGQISQSVSQL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
DQMTQQNAALVEQSTAASESLREQAVQLIGAVRRFRLDDGPAADIALQAPPPPGAASLAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCC
RPLAAALPGPVSGFVRHEPAA
CCHHHHCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]