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The map label for this gene is 120609340

Identifier: 120609340

GI number: 120609340

Start: 690109

End: 691248

Strand: Direct

Name: 120609340

Synonym: Aave_0640

Alternate gene names: NA

Gene position: 690109-691248 (Clockwise)

Preceding gene: 120609338

Following gene: 120609341

Centisome position: 12.89

GC content: 70.88

Gene sequence:

>1140_bases
ATGCCCGGTCTGTTGCCCGATGTCGATCCCGATGGCCTGCTGGAGTTCTCGGTCGTGTACACCGACCGGGCGCTCAACCA
TATGTCCCGCCGGTTCGCCGGGATGGTGCAGGACATCCTCGCCACGCTGAAGTCGGTGTACGGCGCCCACACCGCCGTGC
TCGTTCCCGGCAGCGGCACCTTCGGCATGGAAGCCGTGGCCCGCCAGTTCGCCAACCGCGAGAAGGTGCTGATCGTGCGC
AACGGCTGGTTCAGCTACCGCTGGAGCCAGATTTTCGACGCGGGCGGGCTGGGCGGCGGTGCCGTGGTCTGCCAGGCGCG
CCAGCAGGGCGAGGGCCCGCAGGCCCCCTGGGCGCCGTGCCCGGCCGGCGAGGTGGCGCAGGCCATCCGCGCCGAACGGC
CGAAGGTGGTTTTCGCACCGCACGTGGAGACGGCCAGCGGCATCCTGCTGCCGGACGACTACCTGCGCACCGTGGCGGAG
GCCGCGCACGAGGTGGGCGCGCTGTTCGTGCTGGACTGCGTGGCTTCCGGTGCGATGTGGGTGGACATGCGCGCCACGGG
GGTGGACGTGCTCATCTCCGCGCCGCAGAAGGGCTGGAGCGGCTCGCCCTGCTGCGCCATGGTCATGCTCAGCGAGCGCG
CGCGGCAGGCGATCGAGGGAACGCAGAGTTCCAGCTTCTCCTGCGACCTCAAGAAGTGGATGCAGATCGCGGAAGGCTAC
GAGAAGGGGCAGCATGCCTACCACACGACCATGCCGACCGATGCGCTCGTGCGGCTGCGGGACGTGATGTTCGAGACCCG
CGACGACGGCTTCGAGCGGGTGCGCGAGCGGCAGATCGAACTGGGGGCGAAGGTGCGCGCGCTGCTGGAGTCGCGCGGGT
TCCCGAGCGTGGCGGCCGAGGGCTGGAAGGCGCCGGGCGTGGTGGTGATCTATACCACCGACCCCGGCATCCAGAGCGGC
CGGAAGTTCCTGGAGGCAGGGCTGCAGACTGCCGCGGGCGTGCCGCTGCAGTGCGGCGAGGGCCCGGAGTTCCAGACCTT
CCGCGTCGGCCTGTTCGGGCTGGACAAGTGGCGCAACGTGGACCGCACGGTCGGCCACCTGGCCGCGGCCCTCGACCGGG
TGGCTCCCGCCCGGGGCTGA

Upstream 100 bases:

>100_bases
TGGGGGTGCCTGCGCGCGAAGCCCGGCGTTTCCGGCCCCGGACCGCTTGGGCGCCGGCCCGTCCCCAAGCCTGTTCCCGT
TTCCAAGGAGTTGCCCTGCC

Downstream 100 bases:

>100_bases
CGCCCCGCGCCGTCAGCCCCTGGCGGCGCCAAGAGCGGCTGGCACGGCCCAGCGGAGGCGGTTCTGGCGAAGCGTCGCAC
CGCAGGCAGTACGCGCGGTA

Product: class V aminotransferase

Products: NA

Alternate protein names: Tritium exchange subunit [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MPGLLPDVDPDGLLEFSVVYTDRALNHMSRRFAGMVQDILATLKSVYGAHTAVLVPGSGTFGMEAVARQFANREKVLIVR
NGWFSYRWSQIFDAGGLGGGAVVCQARQQGEGPQAPWAPCPAGEVAQAIRAERPKVVFAPHVETASGILLPDDYLRTVAE
AAHEVGALFVLDCVASGAMWVDMRATGVDVLISAPQKGWSGSPCCAMVMLSERARQAIEGTQSSSFSCDLKKWMQIAEGY
EKGQHAYHTTMPTDALVRLRDVMFETRDDGFERVRERQIELGAKVRALLESRGFPSVAAEGWKAPGVVVIYTTDPGIQSG
RKFLEAGLQTAAGVPLQCGEGPEFQTFRVGLFGLDKWRNVDRTVGHLAAALDRVAPARG

Sequences:

>Translated_379_residues
MPGLLPDVDPDGLLEFSVVYTDRALNHMSRRFAGMVQDILATLKSVYGAHTAVLVPGSGTFGMEAVARQFANREKVLIVR
NGWFSYRWSQIFDAGGLGGGAVVCQARQQGEGPQAPWAPCPAGEVAQAIRAERPKVVFAPHVETASGILLPDDYLRTVAE
AAHEVGALFVLDCVASGAMWVDMRATGVDVLISAPQKGWSGSPCCAMVMLSERARQAIEGTQSSSFSCDLKKWMQIAEGY
EKGQHAYHTTMPTDALVRLRDVMFETRDDGFERVRERQIELGAKVRALLESRGFPSVAAEGWKAPGVVVIYTTDPGIQSG
RKFLEAGLQTAAGVPLQCGEGPEFQTFRVGLFGLDKWRNVDRTVGHLAAALDRVAPARG
>Mature_378_residues
PGLLPDVDPDGLLEFSVVYTDRALNHMSRRFAGMVQDILATLKSVYGAHTAVLVPGSGTFGMEAVARQFANREKVLIVRN
GWFSYRWSQIFDAGGLGGGAVVCQARQQGEGPQAPWAPCPAGEVAQAIRAERPKVVFAPHVETASGILLPDDYLRTVAEA
AHEVGALFVLDCVASGAMWVDMRATGVDVLISAPQKGWSGSPCCAMVMLSERARQAIEGTQSSSFSCDLKKWMQIAEGYE
KGQHAYHTTMPTDALVRLRDVMFETRDDGFERVRERQIELGAKVRALLESRGFPSVAAEGWKAPGVVVIYTTDPGIQSGR
KFLEAGLQTAAGVPLQCGEGPEFQTFRVGLFGLDKWRNVDRTVGHLAAALDRVAPARG

Specific function: Soluble hydrogenase catalyzes both production and consumption of hydrogen from suitable artificial electron donors or acceptors. This subunit catalyzes the tritium-exchange activity [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=256, Percent_Identity=26.171875, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17536281, Length=345, Percent_Identity=24.3478260869565, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321079, Length=316, Percent_Identity=25, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: NA

Molecular weight: Translated: 40993; Mature: 40862

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGLLPDVDPDGLLEFSVVYTDRALNHMSRRFAGMVQDILATLKSVYGAHTAVLVPGSGT
CCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
FGMEAVARQFANREKVLIVRNGWFSYRWSQIFDAGGLGGGAVVCQARQQGEGPQAPWAPC
CCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCCHHEEEECHHCCCCCCCCCCCC
PAGEVAQAIRAERPKVVFAPHVETASGILLPDDYLRTVAEAAHEVGALFVLDCVASGAMW
CHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VDMRATGVDVLISAPQKGWSGSPCCAMVMLSERARQAIEGTQSSSFSCDLKKWMQIAEGY
EEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
EKGQHAYHTTMPTDALVRLRDVMFETRDDGFERVRERQIELGAKVRALLESRGFPSVAAE
HHCCCCEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHC
GWKAPGVVVIYTTDPGIQSGRKFLEAGLQTAAGVPLQCGEGPEFQTFRVGLFGLDKWRNV
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECHHHCCH
DRTVGHLAAALDRVAPARG
HHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PGLLPDVDPDGLLEFSVVYTDRALNHMSRRFAGMVQDILATLKSVYGAHTAVLVPGSGT
CCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
FGMEAVARQFANREKVLIVRNGWFSYRWSQIFDAGGLGGGAVVCQARQQGEGPQAPWAPC
CCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCCHHEEEECHHCCCCCCCCCCCC
PAGEVAQAIRAERPKVVFAPHVETASGILLPDDYLRTVAEAAHEVGALFVLDCVASGAMW
CHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VDMRATGVDVLISAPQKGWSGSPCCAMVMLSERARQAIEGTQSSSFSCDLKKWMQIAEGY
EEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
EKGQHAYHTTMPTDALVRLRDVMFETRDDGFERVRERQIELGAKVRALLESRGFPSVAAE
HHCCCCEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHC
GWKAPGVVVIYTTDPGIQSGRKFLEAGLQTAAGVPLQCGEGPEFQTFRVGLFGLDKWRNV
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECHHHCCH
DRTVGHLAAALDRVAPARG
HHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2129525 [H]