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The map label for this gene is trpD

Identifier: 120609285

GI number: 120609285

Start: 637764

End: 638801

Strand: Direct

Name: trpD

Synonym: Aave_0585

Alternate gene names: 120609285

Gene position: 637764-638801 (Clockwise)

Preceding gene: 120609284

Following gene: 120609286

Centisome position: 11.91

GC content: 69.75

Gene sequence:

>1038_bases
ATGTCCATCACCCCCCAGGAAGCGCTGCAGCGCACGATCGAGCACCGCGAAATCTTCCACGACGAGATGCTGCACCTCAT
GCGCATGATCATGCGCGGCGAGCTGTCCCCCGTGATGACCGCGGCCATCGTCACCGGCCTGCGCGTCAAGAAGGAAACCA
TCGGCGAGATCACCGCGGCGGCGCAGGTGATGCGCGAGCTCTCCCGCAAGGTGGCCGTGGCCGACACCACCCACCTGGTG
GACATCGTGGGCACCGGCGGCGACGGCGCCAATACCTTCAACATCTCCACCTGCGCCATGTTCGTGGCCGCGGCGGCGGG
CGCCAAGACCGCCAAGCACGGCGGCCGGGGCGTATCGAGCAAGAGCGGCAGCGCCGACGTGATGGAGTCGCTGGGCGTCC
ATATCGACCTGCCGCCCGAGGCCATCGCACGCTGCATCGCCGACACGGGTATCGGCTTCATGTTCGCCCCCAACCACCAC
CCGGCCATGAAGAACGTGGCGCCCGTGCGCAAGGAACTGGGCGTGCGCACGCTCTTCAACATCCTCGGGCCGCTCACCAA
CCCTGCCGGCGCGCCGAACATCCTCATGGGCGTGTTCCACCCCGACCTCGTGGGCATCCAGGTGCGCGCGCTGCAGCGGC
TGGGCGCGGAGCACGCGCTGGTCGTCTATGGCCGCGACGGCATGGACGAGGTGAGCCTGGGCGCGGCCACCATGGTGGGC
GAGCTGAAGAACGGCGAGATCACCGAATACGAAATCCATCCGGAAGACTTCGGCCTGGCGATGTCGAGCAACCGCGCCCT
CAAGGTGGAGACGCCCGAGCAGTCGCGCGAGATGCTGCTGTCGGTGCTGCGTGGCGAACCGGGCTCCGCGCGCGAGATCG
TCTGTCTGAACGCGGGCGTGGCGCTCTACGCGGCGAACGTGGCCGCGACCATGGCCGACGGCATTGCGCGGGCCCGCGCG
GCGCTGGACTCCGGCGCGGCGCTCGCGCGGCTGGAGCAACTGGTGGCGCGCACCCGGGCCCTGGCCGCCGGCGGCTGA

Upstream 100 bases:

>100_bases
GCGCGGCCGGCGCCATGTTCGTCGGCTTCGGCATCAGGCTCGCGCTGTCCGAGCGGCCGGGCCCCTGAATCTCCCGATCT
CCAGAAAAAGGCTTCCCGCC

Downstream 100 bases:

>100_bases
GGCGCCAGCCGGCCGGAACCGCCCATGTGGCGCGACAGCGGAACCTGGATCGCCCTCGGCGTATCCCTGCTATTCATCGT
GGCGGGCATCGTGATGCACC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MSITPQEALQRTIEHREIFHDEMLHLMRMIMRGELSPVMTAAIVTGLRVKKETIGEITAAAQVMRELSRKVAVADTTHLV
DIVGTGGDGANTFNISTCAMFVAAAAGAKTAKHGGRGVSSKSGSADVMESLGVHIDLPPEAIARCIADTGIGFMFAPNHH
PAMKNVAPVRKELGVRTLFNILGPLTNPAGAPNILMGVFHPDLVGIQVRALQRLGAEHALVVYGRDGMDEVSLGAATMVG
ELKNGEITEYEIHPEDFGLAMSSNRALKVETPEQSREMLLSVLRGEPGSAREIVCLNAGVALYAANVAATMADGIARARA
ALDSGAALARLEQLVARTRALAAGG

Sequences:

>Translated_345_residues
MSITPQEALQRTIEHREIFHDEMLHLMRMIMRGELSPVMTAAIVTGLRVKKETIGEITAAAQVMRELSRKVAVADTTHLV
DIVGTGGDGANTFNISTCAMFVAAAAGAKTAKHGGRGVSSKSGSADVMESLGVHIDLPPEAIARCIADTGIGFMFAPNHH
PAMKNVAPVRKELGVRTLFNILGPLTNPAGAPNILMGVFHPDLVGIQVRALQRLGAEHALVVYGRDGMDEVSLGAATMVG
ELKNGEITEYEIHPEDFGLAMSSNRALKVETPEQSREMLLSVLRGEPGSAREIVCLNAGVALYAANVAATMADGIARARA
ALDSGAALARLEQLVARTRALAAGG
>Mature_344_residues
SITPQEALQRTIEHREIFHDEMLHLMRMIMRGELSPVMTAAIVTGLRVKKETIGEITAAAQVMRELSRKVAVADTTHLVD
IVGTGGDGANTFNISTCAMFVAAAAGAKTAKHGGRGVSSKSGSADVMESLGVHIDLPPEAIARCIADTGIGFMFAPNHHP
AMKNVAPVRKELGVRTLFNILGPLTNPAGAPNILMGVFHPDLVGIQVRALQRLGAEHALVVYGRDGMDEVSLGAATMVGE
LKNGEITEYEIHPEDFGLAMSSNRALKVETPEQSREMLLSVLRGEPGSAREIVCLNAGVALYAANVAATMADGIARARAA
LDSGAALARLEQLVARTRALAAGG

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=283, Percent_Identity=42.0494699646643, Blast_Score=206, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6320561, Length=362, Percent_Identity=30.1104972375691, Blast_Score=133, Evalue=4e-32,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_ACIAC (A1TJQ1)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_968963.1
- ProteinModelPortal:   A1TJQ1
- SMR:   A1TJQ1
- STRING:   A1TJQ1
- GeneID:   4668139
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_0585
- NMPDR:   fig|397945.5.peg.501
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- PhylomeDB:   A1TJQ1
- ProtClustDB:   PRK00188
- BioCyc:   AAVE397945:AAVE_0585-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36355; Mature: 36223

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITPQEALQRTIEHREIFHDEMLHLMRMIMRGELSPVMTAAIVTGLRVKKETIGEITAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AQVMRELSRKVAVADTTHLVDIVGTGGDGANTFNISTCAMFVAAAAGAKTAKHGGRGVSS
HHHHHHHHHHEECCCCCEEEEEEECCCCCCCEEEHHHHHHHHHHHCCCHHHHCCCCCCCC
KSGSADVMESLGVHIDLPPEAIARCIADTGIGFMFAPNHHPAMKNVAPVRKELGVRTLFN
CCCCHHHHHHCCCEEECCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHH
ILGPLTNPAGAPNILMGVFHPDLVGIQVRALQRLGAEHALVVYGRDGMDEVSLGAATMVG
HHCCCCCCCCCCHHEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHH
ELKNGEITEYEIHPEDFGLAMSSNRALKVETPEQSREMLLSVLRGEPGSAREIVCLNAGV
HCCCCCEEEEEECCHHHCEEECCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEEEEECCH
ALYAANVAATMADGIARARAALDSGAALARLEQLVARTRALAAGG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SITPQEALQRTIEHREIFHDEMLHLMRMIMRGELSPVMTAAIVTGLRVKKETIGEITAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AQVMRELSRKVAVADTTHLVDIVGTGGDGANTFNISTCAMFVAAAAGAKTAKHGGRGVSS
HHHHHHHHHHEECCCCCEEEEEEECCCCCCCEEEHHHHHHHHHHHCCCHHHHCCCCCCCC
KSGSADVMESLGVHIDLPPEAIARCIADTGIGFMFAPNHHPAMKNVAPVRKELGVRTLFN
CCCCHHHHHHCCCEEECCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHH
ILGPLTNPAGAPNILMGVFHPDLVGIQVRALQRLGAEHALVVYGRDGMDEVSLGAATMVG
HHCCCCCCCCCCHHEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHH
ELKNGEITEYEIHPEDFGLAMSSNRALKVETPEQSREMLLSVLRGEPGSAREIVCLNAGV
HCCCCCEEEEEECCHHHCEEECCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEEEEECCH
ALYAANVAATMADGIARARAALDSGAALARLEQLVARTRALAAGG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA