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The map label for this gene is rpe [H]

Identifier: 120609141

GI number: 120609141

Start: 475959

End: 476639

Strand: Direct

Name: rpe [H]

Synonym: Aave_0438

Alternate gene names: 120609141

Gene position: 475959-476639 (Clockwise)

Preceding gene: 120609136

Following gene: 120609143

Centisome position: 8.89

GC content: 67.99

Gene sequence:

>681_bases
ATGACCCGCCAATTCCGCATCGCCCCCTCGATCCTGTCCGCCGATTTCGCCCGCCTGGGCGAGGAAGTGAAGAATGTCAT
CGCCTCCGGCGCCGACTGGGTGCACTTCGACGTGATGGACAACCACTACGTGCCCAACCTCACCTTCGGCCCGATGGTGT
GCCAGGCGCTCAAGCCCCATGCCGTCACGCCCGACGGCCGGCCCGCGCCGATCGACGTGCACCTGATGGTGCAGCCCGTG
GACGCCCTGGCCGCGGCCTTCGCGGAGGCGGGAGCGGACTACATCAGCTTCCATCCGGATGCGTCCGCGCACGTGCACCG
CAGCATCCAGGCGATCACCTCCAAGGGCATCAAGGCGGGCCTGGTGTTCAACCCGGCGGCCCCGCTCGACGTGCTGGACT
GGGTGATCGACGACATCGACCTGATCCTCGTGATGAGCGTGAACCCGGGCTTCGGCGGCCAGAGCTTCATCGATTCGGCG
CTGCGCAAGATCGAGGCCCTGCGCCGCCGCATCGACGCCTGCGGCAAGGACATCCGCCTGGAGGTGGACGGAGGGGTGAA
GGTGGACAACATCCGCCGCGTGGCGGACGCCGGTGCCGATACGTTCGTTGCGGGCAGCGCGATCTTCGGCAAGCCCGACT
ATCGCGCCGTGATCGACGCGATGCGCGCCCAGCTCGGCTGA

Upstream 100 bases:

>100_bases
GGGCCGGGCGGCTCGGCCGTTGCGTCGGCGGGCGCCGTGACCCGGCGCAGGAGCCCTGAGGAAGGCGTGCCGCGGCGCCT
CTGCTGCGACAATCCGGGCC

Downstream 100 bases:

>100_bases
GGCGCGCTGGCACCCGGGCCGCAGGGCCGGCCCGGCGTGCGGTCCCTTATCGCTGGGGCATCGGCTGGGGCGCAGGTTGC
GTCATCGGCTGGGGCATGGG

Product: ribulose-5-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTRQFRIAPSILSADFARLGEEVKNVIASGADWVHFDVMDNHYVPNLTFGPMVCQALKPHAVTPDGRPAPIDVHLMVQPV
DALAAAFAEAGADYISFHPDASAHVHRSIQAITSKGIKAGLVFNPAAPLDVLDWVIDDIDLILVMSVNPGFGGQSFIDSA
LRKIEALRRRIDACGKDIRLEVDGGVKVDNIRRVADAGADTFVAGSAIFGKPDYRAVIDAMRAQLG

Sequences:

>Translated_226_residues
MTRQFRIAPSILSADFARLGEEVKNVIASGADWVHFDVMDNHYVPNLTFGPMVCQALKPHAVTPDGRPAPIDVHLMVQPV
DALAAAFAEAGADYISFHPDASAHVHRSIQAITSKGIKAGLVFNPAAPLDVLDWVIDDIDLILVMSVNPGFGGQSFIDSA
LRKIEALRRRIDACGKDIRLEVDGGVKVDNIRRVADAGADTFVAGSAIFGKPDYRAVIDAMRAQLG
>Mature_225_residues
TRQFRIAPSILSADFARLGEEVKNVIASGADWVHFDVMDNHYVPNLTFGPMVCQALKPHAVTPDGRPAPIDVHLMVQPVD
ALAAAFAEAGADYISFHPDASAHVHRSIQAITSKGIKAGLVFNPAAPLDVLDWVIDDIDLILVMSVNPGFGGQSFIDSAL
RKIEALRRRIDACGKDIRLEVDGGVKVDNIRRVADAGADTFVAGSAIFGKPDYRAVIDAMRAQLG

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=222, Percent_Identity=38.7387387387387, Blast_Score=158, Evalue=4e-39,
Organism=Homo sapiens, GI219879828, Length=222, Percent_Identity=36.9369369369369, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI24307923, Length=168, Percent_Identity=32.7380952380952, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI1789788, Length=223, Percent_Identity=65.0224215246637, Blast_Score=296, Evalue=1e-81,
Organism=Escherichia coli, GI1790523, Length=203, Percent_Identity=35.9605911330049, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790754, Length=212, Percent_Identity=29.7169811320755, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17552948, Length=225, Percent_Identity=36.8888888888889, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6322341, Length=226, Percent_Identity=39.3805309734513, Blast_Score=162, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24586301, Length=222, Percent_Identity=36.4864864864865, Blast_Score=145, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24296; Mature: 24165

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRQFRIAPSILSADFARLGEEVKNVIASGADWVHFDVMDNHYVPNLTFGPMVCQALKPH
CCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCC
AVTPDGRPAPIDVHLMVQPVDALAAAFAEAGADYISFHPDASAHVHRSIQAITSKGIKAG
CCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCEEE
LVFNPAAPLDVLDWVIDDIDLILVMSVNPGFGGQSFIDSALRKIEALRRRIDACGKDIRL
EEECCCCCHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEE
EVDGGVKVDNIRRVADAGADTFVAGSAIFGKPDYRAVIDAMRAQLG
EECCCEEHHHHHHHHHCCCCCEEECCEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRQFRIAPSILSADFARLGEEVKNVIASGADWVHFDVMDNHYVPNLTFGPMVCQALKPH
CCCEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCC
AVTPDGRPAPIDVHLMVQPVDALAAAFAEAGADYISFHPDASAHVHRSIQAITSKGIKAG
CCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCEEE
LVFNPAAPLDVLDWVIDDIDLILVMSVNPGFGGQSFIDSALRKIEALRRRIDACGKDIRL
EEECCCCCHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEE
EVDGGVKVDNIRRVADAGADTFVAGSAIFGKPDYRAVIDAMRAQLG
EECCCEEHHHHHHHHHCCCCCEEECCEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]