Click here to switch to the map view.

The map label for this gene is gph [C]

Identifier: 120609143

GI number: 120609143

Start: 477527

End: 478234

Strand: Direct

Name: gph [C]

Synonym: Aave_0440

Alternate gene names: 120609143

Gene position: 477527-478234 (Clockwise)

Preceding gene: 120609141

Following gene: 120609145

Centisome position: 8.92

GC content: 72.46

Gene sequence:

>708_bases
ATGCTGGAATGTTCCCCGGCGGCGCTGGTGGCGCGCGCCGATGCGGCGATCGTGGACCTGGACGGCACCATGGTGGACAC
CCTGGGCGATTTCGCGGAGGCACTGCGGCGCATGCTCGGCGACCTGTCCCTGCCGGGCATCGACGCGGCGGAGATCGAGC
GCATGGTGGGCAAGGGCACGGAGCACCTGCTGCGCTCGGTGCTGGACCATGTGCTGCAGCCGATGGAGCCGCAGCGCCGC
GCCGCAGCGGTGGAAGCGCACTATCCGCAGGCATGGGAGGCCTACGGGCGGCACTACCTGGCGATCAACGGCAGCCATTC
GCGCGTTTACGAGGGCGTGGCCGAGGGGCTGCAGGCCCTGCGCGCCGCGGGGCTGCGGCTGGCCTGCGTCACCAACAAGC
CCGGGGCCTTCGCCGTGCCCCTGCTGCGGGCCAAGGGGCTGGACGGCTTCTTCGACCACGTCTTCGGCGGGGACGCATTC
GAGCGCAAGAAACCCCATCCGCTGCCGCTGCTCAAGGCCTGCGAGGCCCTGGGAACGGCGCCCGCCCGGACCCTGGCCAT
CGGGGACTCCGTCAACGATGCGCGCGCGGCCCGCGCCGCCGGCTGCCCCGTGGTGCTGGTGACCTATGGCTACAACCACG
GCCAGCCCGCGCGGCAGGTGGACGCGGACGCGCACGTGGACAGCCTGCAGTCGCTGTGCGCGGGCTGA

Upstream 100 bases:

>100_bases
CGGCCTACACTCCCGGCAGCCCCGCCGGCGCCGGATCGCCGGACGGGACCTTATTCACGCACCGCCGCGGCGGGCTTGGC
GGCACTTTGGAGGATGGGAC

Downstream 100 bases:

>100_bases
GGCCGTGCCGCGGCGGGCCGGCGTTCAGCCGGCCTTGCCGAGCAGCGCGTCCTTGAGCTTCCAGTCCGCGGGCTGCGGAC
CGAGCCAGATGGCCATCAGC

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MLECSPAALVARADAAIVDLDGTMVDTLGDFAEALRRMLGDLSLPGIDAAEIERMVGKGTEHLLRSVLDHVLQPMEPQRR
AAAVEAHYPQAWEAYGRHYLAINGSHSRVYEGVAEGLQALRAAGLRLACVTNKPGAFAVPLLRAKGLDGFFDHVFGGDAF
ERKKPHPLPLLKACEALGTAPARTLAIGDSVNDARAARAAGCPVVLVTYGYNHGQPARQVDADAHVDSLQSLCAG

Sequences:

>Translated_235_residues
MLECSPAALVARADAAIVDLDGTMVDTLGDFAEALRRMLGDLSLPGIDAAEIERMVGKGTEHLLRSVLDHVLQPMEPQRR
AAAVEAHYPQAWEAYGRHYLAINGSHSRVYEGVAEGLQALRAAGLRLACVTNKPGAFAVPLLRAKGLDGFFDHVFGGDAF
ERKKPHPLPLLKACEALGTAPARTLAIGDSVNDARAARAAGCPVVLVTYGYNHGQPARQVDADAHVDSLQSLCAG
>Mature_235_residues
MLECSPAALVARADAAIVDLDGTMVDTLGDFAEALRRMLGDLSLPGIDAAEIERMVGKGTEHLLRSVLDHVLQPMEPQRR
AAAVEAHYPQAWEAYGRHYLAINGSHSRVYEGVAEGLQALRAAGLRLACVTNKPGAFAVPLLRAKGLDGFFDHVFGGDAF
ERKKPHPLPLLKACEALGTAPARTLAIGDSVNDARAARAAGCPVVLVTYGYNHGQPARQVDADAHVDSLQSLCAG

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=224, Percent_Identity=37.0535714285714, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR000150
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 24925; Mature: 24925

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLECSPAALVARADAAIVDLDGTMVDTLGDFAEALRRMLGDLSLPGIDAAEIERMVGKGT
CCCCCHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCH
EHLLRSVLDHVLQPMEPQRRAAAVEAHYPQAWEAYGRHYLAINGSHSRVYEGVAEGLQAL
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHCCEEEEEECCHHHHHHHHHHHHHHH
RAAGLRLACVTNKPGAFAVPLLRAKGLDGFFDHVFGGDAFERKKPHPLPLLKACEALGTA
HHCCCEEEEEECCCCCEEHHHHHHCCCCHHHHHHCCCCHHHCCCCCCCHHHHHHHHHCCC
PARTLAIGDSVNDARAARAAGCPVVLVTYGYNHGQPARQVDADAHVDSLQSLCAG
CCCEEEECCCCCHHHHHHHCCCCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLECSPAALVARADAAIVDLDGTMVDTLGDFAEALRRMLGDLSLPGIDAAEIERMVGKGT
CCCCCHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCH
EHLLRSVLDHVLQPMEPQRRAAAVEAHYPQAWEAYGRHYLAINGSHSRVYEGVAEGLQAL
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHCCEEEEEECCHHHHHHHHHHHHHHH
RAAGLRLACVTNKPGAFAVPLLRAKGLDGFFDHVFGGDAFERKKPHPLPLLKACEALGTA
HHCCCEEEEEECCCCCEEHHHHHHCCCCHHHHHHCCCCHHHCCCCCCCHHHHHHHHHCCC
PARTLAIGDSVNDARAARAAGCPVVLVTYGYNHGQPARQVDADAHVDSLQSLCAG
CCCEEEECCCCCHHHHHHHCCCCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA