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The map label for this gene is lig [H]

Identifier: 120609077

GI number: 120609077

Start: 399781

End: 400896

Strand: Direct

Name: lig [H]

Synonym: Aave_0374

Alternate gene names: 120609077

Gene position: 399781-400896 (Clockwise)

Preceding gene: 120609076

Following gene: 120609078

Centisome position: 7.47

GC content: 71.42

Gene sequence:

>1116_bases
ATGGCGGCTGCTTCCGATGACCTGGTGATCGCGCGGCCCGAGGGGCTCTACTGTCCTCCGGGCGATTTCTACATCGATCC
CTGGAAGCCCGTGGAGCGGGCGGTCATCACGCACGGGCACTCGGACCACGCCCGCTGGGGCCACTCCCATTACCTGGCCC
ACATCGACAGCGAAGGGACCTTGCGCGCCCGGCTCGGGGCCGACATCACGCTGCAGACGCTGCCGTACGGGCAGGCCATC
CAACACCACGGCGTGCGCATCTCGCTGCATCCCGCAGGCCACGTGCTCGGGTCGGCCCAGGTGCGTCTGGAGCATGGCGG
CCGCGTCTGGGTGGCCTCGGGTGACTACAAGACCGGACCCGACGGCACCTGCGTGCCCTTCGAGCCGGTGCGCTGCGACA
CCTTCATCACCGAGTCCACCTTCGGCCTGCCGATCTACCGCTGGCCCTCGCAGGAGGTGCTGTTCGCCGAGATCGACGCA
TGGTGGCGCGCGAACGCCGCGCAGGGGCGGCCGTCGGTGATGCTGTGCTATGCCTTCGGCAAGGCACAGCGCATCCTGCA
CGGCGTGGACGCCTCGATCGGGCCCATCGTGGTCCATGGCGCGGTGGAGCCGCTCAATGCCGTGTACCGTGCGGCCGGCG
TGGCGCTGCCCCCGACGCTGCGGGCCACGGATCCGGGCGTGGACGCGAAGCTGCTGCAGACGGCCCTGGTGGTCGCCCCC
CCTTCGGCCCAGGGCACGCCCTGGATGCGCCGCTTCCCCCGGCATTCCGATGCGTTCGCGAGCGGCTGGATGCAGCTGCG
GGGCACCCGGCGCCGGCGCGGCGTGGACCGGGGCTTCGTGATGTCGGACCATGCGGACTGGCCCGGCCTGCAGTCGGCCA
TCGGCGCCACCGGGGCGGAGCGCGTCTTCGTGACGCATGGCAGCGTGGCCGTGCTGGTGCGCTGGCTCCGGGAGCAGGGA
CTGGATGCGCAGTCGTTCCGCACGGAATACGGCAACGAGGACGATGATGCGGCGCCGGATGCCTCCACGGCTACACCGCC
GGTCGCCGCGCCGGGCGGTGATGCTTCGCCTGTCGAAGACGATGGCCCGCCAGAGGGCGGGGAAGCGGCGCCATGA

Upstream 100 bases:

>100_bases
CACACCAGGGCTTTCTTCCTTCTACGTACGTCGCATTGGGCGGCGGGGTCAGCGGGGCGGCGGGTTGGCGCTTTCCTCCA
TTCCATGGAAGGGCTTGCCC

Downstream 100 bases:

>100_bases
AGGACTTTGCCGCTCTCTACCGCGCGCTGGACGCGAGCACCTCCAGCCTCGCCAAGCAGGCGGCGCTGCAGGCTTACCTG
CGCGCGGCGGCACCTGCGGA

Product: putative mRNA 3-end processing factor

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MAAASDDLVIARPEGLYCPPGDFYIDPWKPVERAVITHGHSDHARWGHSHYLAHIDSEGTLRARLGADITLQTLPYGQAI
QHHGVRISLHPAGHVLGSAQVRLEHGGRVWVASGDYKTGPDGTCVPFEPVRCDTFITESTFGLPIYRWPSQEVLFAEIDA
WWRANAAQGRPSVMLCYAFGKAQRILHGVDASIGPIVVHGAVEPLNAVYRAAGVALPPTLRATDPGVDAKLLQTALVVAP
PSAQGTPWMRRFPRHSDAFASGWMQLRGTRRRRGVDRGFVMSDHADWPGLQSAIGATGAERVFVTHGSVAVLVRWLREQG
LDAQSFRTEYGNEDDDAAPDASTATPPVAAPGGDASPVEDDGPPEGGEAAP

Sequences:

>Translated_371_residues
MAAASDDLVIARPEGLYCPPGDFYIDPWKPVERAVITHGHSDHARWGHSHYLAHIDSEGTLRARLGADITLQTLPYGQAI
QHHGVRISLHPAGHVLGSAQVRLEHGGRVWVASGDYKTGPDGTCVPFEPVRCDTFITESTFGLPIYRWPSQEVLFAEIDA
WWRANAAQGRPSVMLCYAFGKAQRILHGVDASIGPIVVHGAVEPLNAVYRAAGVALPPTLRATDPGVDAKLLQTALVVAP
PSAQGTPWMRRFPRHSDAFASGWMQLRGTRRRRGVDRGFVMSDHADWPGLQSAIGATGAERVFVTHGSVAVLVRWLREQG
LDAQSFRTEYGNEDDDAAPDASTATPPVAAPGGDASPVEDDGPPEGGEAAP
>Mature_370_residues
AAASDDLVIARPEGLYCPPGDFYIDPWKPVERAVITHGHSDHARWGHSHYLAHIDSEGTLRARLGADITLQTLPYGQAIQ
HHGVRISLHPAGHVLGSAQVRLEHGGRVWVASGDYKTGPDGTCVPFEPVRCDTFITESTFGLPIYRWPSQEVLFAEIDAW
WRANAAQGRPSVMLCYAFGKAQRILHGVDASIGPIVVHGAVEPLNAVYRAAGVALPPTLRATDPGVDAKLLQTALVVAPP
SAQGTPWMRRFPRHSDAFASGWMQLRGTRRRRGVDRGFVMSDHADWPGLQSAIGATGAERVFVTHGSVAVLVRWLREQGL
DAQSFRTEYGNEDDDAAPDASTATPPVAAPGGDASPVEDDGPPEGGEAAP

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011108 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N; PF07521 RMMBL [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 39880; Mature: 39749

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAASDDLVIARPEGLYCPPGDFYIDPWKPVERAVITHGHSDHARWGHSHYLAHIDSEGT
CCCCCCCEEEECCCCCCCCCCCCEECCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCE
LRARLGADITLQTLPYGQAIQHHGVRISLHPAGHVLGSAQVRLEHGGRVWVASGDYKTGP
EEEECCCCEEEEECCCCHHHHHCCEEEEECCCCCEECCEEEEEECCCEEEEECCCCCCCC
DGTCVPFEPVRCDTFITESTFGLPIYRWPSQEVLFAEIDAWWRANAAQGRPSVMLCYAFG
CCCCCCCCCCCCCEEEECCCCCCEEEECCCCCEEEEEECHHHCCCCCCCCCCEEEEEECC
KAQRILHGVDASIGPIVVHGAVEPLNAVYRAAGVALPPTLRATDPGVDAKLLQTALVVAP
HHHHHHHHCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHEEEEEEC
PSAQGTPWMRRFPRHSDAFASGWMQLRGTRRRRGVDRGFVMSDHADWPGLQSAIGATGAE
CCCCCCHHHHHCCCCCHHHHHHHHHHCCCHHHCCCCCCEEEECCCCCCCHHHHHCCCCCC
RVFVTHGSVAVLVRWLREQGLDAQSFRTEYGNEDDDAAPDASTATPPVAAPGGDASPVED
EEEEECCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DGPPEGGEAAP
CCCCCCCCCCC
>Mature Secondary Structure 
AAASDDLVIARPEGLYCPPGDFYIDPWKPVERAVITHGHSDHARWGHSHYLAHIDSEGT
CCCCCCEEEECCCCCCCCCCCCEECCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCE
LRARLGADITLQTLPYGQAIQHHGVRISLHPAGHVLGSAQVRLEHGGRVWVASGDYKTGP
EEEECCCCEEEEECCCCHHHHHCCEEEEECCCCCEECCEEEEEECCCEEEEECCCCCCCC
DGTCVPFEPVRCDTFITESTFGLPIYRWPSQEVLFAEIDAWWRANAAQGRPSVMLCYAFG
CCCCCCCCCCCCCEEEECCCCCCEEEECCCCCEEEEEECHHHCCCCCCCCCCEEEEEECC
KAQRILHGVDASIGPIVVHGAVEPLNAVYRAAGVALPPTLRATDPGVDAKLLQTALVVAP
HHHHHHHHCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHEEEEEEC
PSAQGTPWMRRFPRHSDAFASGWMQLRGTRRRRGVDRGFVMSDHADWPGLQSAIGATGAE
CCCCCCHHHHHCCCCCHHHHHHHHHHCCCHHHCCCCCCEEEECCCCCCCHHHHHCCCCCC
RVFVTHGSVAVLVRWLREQGLDAQSFRTEYGNEDDDAAPDASTATPPVAAPGGDASPVED
EEEEECCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DGPPEGGEAAP
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA