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The map label for this gene is atpH

Identifier: 120609072

GI number: 120609072

Start: 394438

End: 394980

Strand: Direct

Name: atpH

Synonym: Aave_0369

Alternate gene names: 120609072

Gene position: 394438-394980 (Clockwise)

Preceding gene: 120609071

Following gene: 120609073

Centisome position: 7.37

GC content: 69.8

Gene sequence:

>543_bases
ATGGCAGAACTCGCCACCATTGCCCGCCCTTACGCGGAAGCCCTGTTCAAGGCCTGCGCAGCCCAGCCGGGCGCCGACCT
GGGCAGCACCGTCGCCTGGGTGGACGAACTGGCGGCGATCGCTGCCGACCCGCAGGTGCGGCAGCTGGCCGACAACCCCA
AGATCGAGTCCGGACAGCTGTTCGACCTGATCGCCGGGGTGGTGCGCGCGCCGCTCTCCGATGCGGCCCGCAACTTCCTG
CGCGTGCTCATCGACAACGGCCGCCTCGAAGCGCTGCCCGAGGTGGCTGCGCAGTTCCGCGCCCTGGTCAACCGGCAGAG
CGGCTCGTCCGACGCGGTGGTCCACAGCGCGTTCCCGATCGACGCCGCCGCGCTGGCGGAGCTCGGTGCCTCGCTGGAGA
AGCGCTTCGGCCGCAAGCTGAACCTCTCCGTGCAGCTCGACGAGTCGCTGATTGGCGGCGTGCGCGTGGCCGTGGGCGAC
GAGGTGCTCGACACCTCCGTCAAGGCCCGTCTGGAACAAATGAAAGCGGCCCTCGTCGCTTAA

Upstream 100 bases:

>100_bases
CAAGGGTGCCGAGCAGATCCTCCGCAAGGAGGTCAATGCCGGCGTCCACGCCGATCTGCTGAACCGGCTCAAGACCGAGC
TGTAAGTAAGGGACGCAACC

Downstream 100 bases:

>100_bases
GCGCCCGAGGTTTCGGCTAACCCAAGAAAGAAGGAAAGAGTCATGCAACTCAATCCCGCAGAGATTTCTGAACTGATCAA
GAGCCGCATCGAAGGTCTGG

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MAELATIARPYAEALFKACAAQPGADLGSTVAWVDELAAIAADPQVRQLADNPKIESGQLFDLIAGVVRAPLSDAARNFL
RVLIDNGRLEALPEVAAQFRALVNRQSGSSDAVVHSAFPIDAAALAELGASLEKRFGRKLNLSVQLDESLIGGVRVAVGD
EVLDTSVKARLEQMKAALVA

Sequences:

>Translated_180_residues
MAELATIARPYAEALFKACAAQPGADLGSTVAWVDELAAIAADPQVRQLADNPKIESGQLFDLIAGVVRAPLSDAARNFL
RVLIDNGRLEALPEVAAQFRALVNRQSGSSDAVVHSAFPIDAAALAELGASLEKRFGRKLNLSVQLDESLIGGVRVAVGD
EVLDTSVKARLEQMKAALVA
>Mature_179_residues
AELATIARPYAEALFKACAAQPGADLGSTVAWVDELAAIAADPQVRQLADNPKIESGQLFDLIAGVVRAPLSDAARNFLR
VLIDNGRLEALPEVAAQFRALVNRQSGSSDAVVHSAFPIDAAALAELGASLEKRFGRKLNLSVQLDESLIGGVRVAVGDE
VLDTSVKARLEQMKAALVA

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=175, Percent_Identity=30.2857142857143, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1790173, Length=176, Percent_Identity=34.0909090909091, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_ACIAC (A1TJ38)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_968750.1
- ProteinModelPortal:   A1TJ38
- SMR:   A1TJ38
- STRING:   A1TJ38
- GeneID:   4665361
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_0369
- NMPDR:   fig|397945.5.peg.332
- eggNOG:   COG0712
- HOGENOM:   HBG668108
- OMA:   ASLERKF
- PhylomeDB:   A1TJ38
- ProtClustDB:   PRK05758
- BioCyc:   AAVE397945:AAVE_0369-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 18930; Mature: 18799

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELATIARPYAEALFKACAAQPGADLGSTVAWVDELAAIAADPQVRQLADNPKIESGQL
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHH
FDLIAGVVRAPLSDAARNFLRVLIDNGRLEALPEVAAQFRALVNRQSGSSDAVVHSAFPI
HHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCC
DAAALAELGASLEKRFGRKLNLSVQLDESLIGGVRVAVGDEVLDTSVKARLEQMKAALVA
CHHHHHHHHHHHHHHCCCEECEEEEECHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AELATIARPYAEALFKACAAQPGADLGSTVAWVDELAAIAADPQVRQLADNPKIESGQL
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHH
FDLIAGVVRAPLSDAARNFLRVLIDNGRLEALPEVAAQFRALVNRQSGSSDAVVHSAFPI
HHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCC
DAAALAELGASLEKRFGRKLNLSVQLDESLIGGVRVAVGDEVLDTSVKARLEQMKAALVA
CHHHHHHHHHHHHHHCCCEECEEEEECHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA