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The map label for this gene is cysH [H]

Identifier: 120609014

GI number: 120609014

Start: 345166

End: 345789

Strand: Direct

Name: cysH [H]

Synonym: Aave_0311

Alternate gene names: 120609014

Gene position: 345166-345789 (Clockwise)

Preceding gene: 120609012

Following gene: 120609015

Centisome position: 6.45

GC content: 68.27

Gene sequence:

>624_bases
ATGAGCAGCATCGACCTCGACTGGATCAACGCCGAACTCGGCCACAACGCGCAGGGCCTCGTGGACTGGGCCATCGGCCT
GGGCCAGCCCGCCATCGTCACCACCAACTTCCGCCCGTTCGAGGCCGTGATCCTGCACATGTGCACGCGCGCCCGGCCGG
ACATCCCGGTCGTGTGGATGGACAACGGCTACAACACCGAGGCCACCTACCGGTTCGCCGACGAAGTGACGCGCCAACTC
GGGCTCAACCTGCGCATCTACCTGCCGCTGCGCTCGCGTGCCCACCGCGAGGCGGTGGACGGTCCCACGCCTGCGCTGGA
CGACCCCCGCCACGCCGCGTTCACGCAGGAGGTCAAGCTCGAGCCCTTCGCGCGGGCCCTGCGGGAGACGGCCCCCAAGG
TCTGGTTCACGGCCCTGCGCGCCACCGATACGGCCGTGCGTGCGCGGATGGATCCGGTGAGCCTCAACCCCGACGGCCTC
ATCAAGGTCGCGCCGCTGCTGCACTGGAGCTCCAAGGACCTGTACGAGTACTGCCAGGCGCAGGGCCTGCCCAACAATTT
CGACTACGTGGATCCGACCAAAGGCGAAGACAACCGGGAGTGCGGCCTGCATCTGGCCCACTGA

Upstream 100 bases:

>100_bases
CCAATAAACGAAATAAAACCGCAGCGCGGCACAATGCCAGCCTTGCCGCCACTTCTTCCTTCCCTTTTCTTGCAGCGCGG
CAACGGAGCCACGCATTCCC

Downstream 100 bases:

>100_bases
CAGCGCGCCCGTGGCGGCGCCTCTCTCCACCCCGAAGGGCATGCTTGCATGCCCTTTTTTTATGCCTGGGTGCTCACGTG
GGCAGTAGTCCTGGGCTGAC

Product: phosphoadenylylsulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSSIDLDWINAELGHNAQGLVDWAIGLGQPAIVTTNFRPFEAVILHMCTRARPDIPVVWMDNGYNTEATYRFADEVTRQL
GLNLRIYLPLRSRAHREAVDGPTPALDDPRHAAFTQEVKLEPFARALRETAPKVWFTALRATDTAVRARMDPVSLNPDGL
IKVAPLLHWSSKDLYEYCQAQGLPNNFDYVDPTKGEDNRECGLHLAH

Sequences:

>Translated_207_residues
MSSIDLDWINAELGHNAQGLVDWAIGLGQPAIVTTNFRPFEAVILHMCTRARPDIPVVWMDNGYNTEATYRFADEVTRQL
GLNLRIYLPLRSRAHREAVDGPTPALDDPRHAAFTQEVKLEPFARALRETAPKVWFTALRATDTAVRARMDPVSLNPDGL
IKVAPLLHWSSKDLYEYCQAQGLPNNFDYVDPTKGEDNRECGLHLAH
>Mature_206_residues
SSIDLDWINAELGHNAQGLVDWAIGLGQPAIVTTNFRPFEAVILHMCTRARPDIPVVWMDNGYNTEATYRFADEVTRQLG
LNLRIYLPLRSRAHREAVDGPTPALDDPRHAAFTQEVKLEPFARALRETAPKVWFTALRATDTAVRARMDPVSLNPDGLI
KVAPLLHWSSKDLYEYCQAQGLPNNFDYVDPTKGEDNRECGLHLAH

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=176, Percent_Identity=37.5, Blast_Score=109, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR011800
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 23304; Mature: 23172

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIDLDWINAELGHNAQGLVDWAIGLGQPAIVTTNFRPFEAVILHMCTRARPDIPVVWM
CCCCCCEEECCCCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEC
DNGYNTEATYRFADEVTRQLGLNLRIYLPLRSRAHREAVDGPTPALDDPRHAAFTQEVKL
CCCCCCCCEEHHHHHHHHHHCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCHHHHHHCCC
EPFARALRETAPKVWFTALRATDTAVRARMDPVSLNPDGLIKVAPLLHWSSKDLYEYCQA
CHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHH
QGLPNNFDYVDPTKGEDNRECGLHLAH
CCCCCCCCCCCCCCCCCCCCCCCEECC
>Mature Secondary Structure 
SSIDLDWINAELGHNAQGLVDWAIGLGQPAIVTTNFRPFEAVILHMCTRARPDIPVVWM
CCCCCEEECCCCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEC
DNGYNTEATYRFADEVTRQLGLNLRIYLPLRSRAHREAVDGPTPALDDPRHAAFTQEVKL
CCCCCCCCEEHHHHHHHHHHCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCHHHHHHCCC
EPFARALRETAPKVWFTALRATDTAVRARMDPVSLNPDGLIKVAPLLHWSSKDLYEYCQA
CHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHH
QGLPNNFDYVDPTKGEDNRECGLHLAH
CCCCCCCCCCCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1463852 [H]