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The map label for this gene is hbpA [H]

Identifier: 120608958

GI number: 120608958

Start: 284389

End: 285984

Strand: Direct

Name: hbpA [H]

Synonym: Aave_0255

Alternate gene names: 120608958

Gene position: 284389-285984 (Clockwise)

Preceding gene: 120608957

Following gene: 120608961

Centisome position: 5.31

GC content: 67.48

Gene sequence:

>1596_bases
ATGCGATTTTCCCGCACCCTTCTGGCGGCCTCCCTCGCGGCCGCGCTCACGGCGGCCCTGCCGCTGGCCACGCAGGCCGC
CACCTTCCGCTTCGCCCGTTCGGCCGACGTGACCACCTGGGACGTGCATGCCCACAACGTGGGCCCGAACAACGTGCTGC
ATTCGGCCGTGTACGAGACGCTGGTCGAATACAACAGCAAGACCTTCAAGCCCGAGCCGCAGCTGGCCACCGCCTGGAAG
CAGGTGAGCCCGACGCAGCTGCGCCTCACCCTGCGCCAGGGCGTGAAGTTCAGCGACGGCTCGCCGCTCACGGCCGAGGA
CGTGAAGTTCTCGCTGGAGCGCGCGAAGGCCAAGACCTCCAACTACGCGGTGTACGCGCAGGGCATCGACCGCGTGCAGG
TGGTGGATGCGCAGACGATCGACATCTTCTCGGACGTGCCCAACCCCGTGCTGGTGAACCAGCTCACCGAGCTGCGCATC
CTGAGCAAGCCCTGGGCCGAGAAGAACAACGCCCTCACGCCCAAGGACATCAAGACCAGCGACGAGCCCTACACCCACCG
CAATGCGCTCGGCACGGGGCCGTTCGTGCTCAAGTCGTGGTCGCCCGACCAGCGCACCGTGCTCGCGGCCAACCCCTACT
GGTGGGGCAAGGGCAAATTCGCAGGCAACGTGACCGATGTGGTCTATACCCCGATCAAGTCCGATGCGACCCGCACCGCG
GCGCTGCTGTCGGGCGAGGTGGACTTCGTGCTCGATCCCAGCCCGCAGGATATCGCCCGCGTGCGCCAGACGCCGGGCTT
CAAGGTGCTGGAAGGCCCGGAAAACCGCACGCTGTTCCTGGGCCTGGACCAGTTCCGCGAGGAGCTGCCCGGATCGAACG
TGAAGGGAAAGAACCCGCTCAAGGACGTGCGCGTGCGCCGCGCCCTCTGCCAGGCGATCGACATCCAGACCATCCAGCGC
GTGACGCTGCGCGGCCTCGCGCAGCCCACGGGCGCGCTGATCGCGCGGCAGGTCAACGGCTGGACGCAGAAGGCCGATGC
GCGCTGGCCCTACGACCCCGCCGCCGCGCAGAAGCTGCTGGCCGACGCGGGCTATCCGCAGGGCTTCGAGGTCGATTTCG
CGTGCAGCGCGGGCCGCTACACGAACGACGAGCAGCTCTGCCAGGCGATCACGGCGCAATGGGCCAAGGTGGGCGTGCGC
GCCAAGCTGCGCACCCAGCCGTTCGCCACGTATTTCCCGATGATCCAGCGCAACGAGGCCAGCATCTACCTGCTGGGCTG
GGGCGTGCCGACCTTCGACGCGTTCTATTCGCTGCAGTCGCTGGTCCGCTCGCCCGGCGCGGGCGGCGACGGCAATTTCA
ACCTGGGCCGCTTCTCCGATCCGCAGCAGGACGCTTTGATCGAGCGCATCAAGAAGGAAACCGATGCCGCCACGCGCAAC
GGCCTCATCGAGCAGGCCCTGCTGAAGGACCACGAGCTGGTCTCGCACATCCCGCTCTACAACCAGATCATTCCCTGGGC
CGCCACCCTGAAGGTGGAACTGCCGCACCGCGCCGACAACCGCATCGACTGGCGCGTGCTGAAGGTGGCGAAGTAA

Upstream 100 bases:

>100_bases
GCATATCGATACAACCACAAAGTCGTTCTGCGCGCAGGGCCGGCTTGGCATAGTGGCTGCCTCGCTGCGGAGCAGCCCAT
CCCGAGACCAGGACACCACC

Downstream 100 bases:

>100_bases
GCGGCCGGCGTACGGGGCGCTCGACGCCGGTGGTGGCCGCCGTCAGCCGGTGACCGTGCCGCTGGCCTCGCCCAGCCCGA
TGCGCGCCGCGCCTTCGCGC

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MRFSRTLLAASLAAALTAALPLATQAATFRFARSADVTTWDVHAHNVGPNNVLHSAVYETLVEYNSKTFKPEPQLATAWK
QVSPTQLRLTLRQGVKFSDGSPLTAEDVKFSLERAKAKTSNYAVYAQGIDRVQVVDAQTIDIFSDVPNPVLVNQLTELRI
LSKPWAEKNNALTPKDIKTSDEPYTHRNALGTGPFVLKSWSPDQRTVLAANPYWWGKGKFAGNVTDVVYTPIKSDATRTA
ALLSGEVDFVLDPSPQDIARVRQTPGFKVLEGPENRTLFLGLDQFREELPGSNVKGKNPLKDVRVRRALCQAIDIQTIQR
VTLRGLAQPTGALIARQVNGWTQKADARWPYDPAAAQKLLADAGYPQGFEVDFACSAGRYTNDEQLCQAITAQWAKVGVR
AKLRTQPFATYFPMIQRNEASIYLLGWGVPTFDAFYSLQSLVRSPGAGGDGNFNLGRFSDPQQDALIERIKKETDAATRN
GLIEQALLKDHELVSHIPLYNQIIPWAATLKVELPHRADNRIDWRVLKVAK

Sequences:

>Translated_531_residues
MRFSRTLLAASLAAALTAALPLATQAATFRFARSADVTTWDVHAHNVGPNNVLHSAVYETLVEYNSKTFKPEPQLATAWK
QVSPTQLRLTLRQGVKFSDGSPLTAEDVKFSLERAKAKTSNYAVYAQGIDRVQVVDAQTIDIFSDVPNPVLVNQLTELRI
LSKPWAEKNNALTPKDIKTSDEPYTHRNALGTGPFVLKSWSPDQRTVLAANPYWWGKGKFAGNVTDVVYTPIKSDATRTA
ALLSGEVDFVLDPSPQDIARVRQTPGFKVLEGPENRTLFLGLDQFREELPGSNVKGKNPLKDVRVRRALCQAIDIQTIQR
VTLRGLAQPTGALIARQVNGWTQKADARWPYDPAAAQKLLADAGYPQGFEVDFACSAGRYTNDEQLCQAITAQWAKVGVR
AKLRTQPFATYFPMIQRNEASIYLLGWGVPTFDAFYSLQSLVRSPGAGGDGNFNLGRFSDPQQDALIERIKKETDAATRN
GLIEQALLKDHELVSHIPLYNQIIPWAATLKVELPHRADNRIDWRVLKVAK
>Mature_531_residues
MRFSRTLLAASLAAALTAALPLATQAATFRFARSADVTTWDVHAHNVGPNNVLHSAVYETLVEYNSKTFKPEPQLATAWK
QVSPTQLRLTLRQGVKFSDGSPLTAEDVKFSLERAKAKTSNYAVYAQGIDRVQVVDAQTIDIFSDVPNPVLVNQLTELRI
LSKPWAEKNNALTPKDIKTSDEPYTHRNALGTGPFVLKSWSPDQRTVLAANPYWWGKGKFAGNVTDVVYTPIKSDATRTA
ALLSGEVDFVLDPSPQDIARVRQTPGFKVLEGPENRTLFLGLDQFREELPGSNVKGKNPLKDVRVRRALCQAIDIQTIQR
VTLRGLAQPTGALIARQVNGWTQKADARWPYDPAAAQKLLADAGYPQGFEVDFACSAGRYTNDEQLCQAITAQWAKVGVR
AKLRTQPFATYFPMIQRNEASIYLLGWGVPTFDAFYSLQSLVRSPGAGGDGNFNLGRFSDPQQDALIERIKKETDAATRN
GLIEQALLKDHELVSHIPLYNQIIPWAATLKVELPHRADNRIDWRVLKVAK

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=513, Percent_Identity=27.6803118908382, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789397, Length=535, Percent_Identity=26.5420560747664, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1787052, Length=490, Percent_Identity=23.8775510204082, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1787495, Length=526, Percent_Identity=24.7148288973384, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI87081878, Length=467, Percent_Identity=24.4111349036403, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787762, Length=504, Percent_Identity=24.2063492063492, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789887, Length=524, Percent_Identity=23.6641221374046, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787551, Length=393, Percent_Identity=22.3918575063613, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 58847; Mature: 58847

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFSRTLLAASLAAALTAALPLATQAATFRFARSADVTTWDVHAHNVGPNNVLHSAVYET
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCHHHHHHHHHHHH
LVEYNSKTFKPEPQLATAWKQVSPTQLRLTLRQGVKFSDGSPLTAEDVKFSLERAKAKTS
HHHCCCCCCCCCCHHHHHHHHCCCHHEEEEHHHCCEECCCCCCCHHHHHHHHHHHHCCCC
NYAVYAQGIDRVQVVDAQTIDIFSDVPNPVLVNQLTELRILSKPWAEKNNALTPKDIKTS
CEEEEECCCCEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
DEPYTHRNALGTGPFVLKSWSPDQRTVLAANPYWWGKGKFAGNVTDVVYTPIKSDATRTA
CCCCCCCCCCCCCCEEEECCCCCCCEEEEECCEECCCCCCCCCCCEEEEECCCCCCHHHH
ALLSGEVDFVLDPSPQDIARVRQTPGFKVLEGPENRTLFLGLDQFREELPGSNVKGKNPL
HHHCCCEEEEECCCHHHHHHHHCCCCCEEEECCCCCEEEEEHHHHHHHCCCCCCCCCCCH
KDVRVRRALCQAIDIQTIQRVTLRGLAQPTGALIARQVNGWTQKADARWPYDPAAAQKLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
ADAGYPQGFEVDFACSAGRYTNDEQLCQAITAQWAKVGVRAKLRTQPFATYFPMIQRNEA
HHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHCCCEECCCC
SIYLLGWGVPTFDAFYSLQSLVRSPGAGGDGNFNLGRFSDPQQDALIERIKKETDAATRN
EEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GLIEQALLKDHELVSHIPLYNQIIPWAATLKVELPHRADNRIDWRVLKVAK
HHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEEECCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MRFSRTLLAASLAAALTAALPLATQAATFRFARSADVTTWDVHAHNVGPNNVLHSAVYET
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCHHHHHHHHHHHH
LVEYNSKTFKPEPQLATAWKQVSPTQLRLTLRQGVKFSDGSPLTAEDVKFSLERAKAKTS
HHHCCCCCCCCCCHHHHHHHHCCCHHEEEEHHHCCEECCCCCCCHHHHHHHHHHHHCCCC
NYAVYAQGIDRVQVVDAQTIDIFSDVPNPVLVNQLTELRILSKPWAEKNNALTPKDIKTS
CEEEEECCCCEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
DEPYTHRNALGTGPFVLKSWSPDQRTVLAANPYWWGKGKFAGNVTDVVYTPIKSDATRTA
CCCCCCCCCCCCCCEEEECCCCCCCEEEEECCEECCCCCCCCCCCEEEEECCCCCCHHHH
ALLSGEVDFVLDPSPQDIARVRQTPGFKVLEGPENRTLFLGLDQFREELPGSNVKGKNPL
HHHCCCEEEEECCCHHHHHHHHCCCCCEEEECCCCCEEEEEHHHHHHHCCCCCCCCCCCH
KDVRVRRALCQAIDIQTIQRVTLRGLAQPTGALIARQVNGWTQKADARWPYDPAAAQKLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
ADAGYPQGFEVDFACSAGRYTNDEQLCQAITAQWAKVGVRAKLRTQPFATYFPMIQRNEA
HHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHCCCEECCCC
SIYLLGWGVPTFDAFYSLQSLVRSPGAGGDGNFNLGRFSDPQQDALIERIKKETDAATRN
EEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GLIEQALLKDHELVSHIPLYNQIIPWAATLKVELPHRADNRIDWRVLKVAK
HHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEEECCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]