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The map label for this gene is csd [H]

Identifier: 120608913

GI number: 120608913

Start: 229700

End: 231085

Strand: Direct

Name: csd [H]

Synonym: Aave_0206

Alternate gene names: 120608913

Gene position: 229700-231085 (Clockwise)

Preceding gene: 120608912

Following gene: 120608920

Centisome position: 4.29

GC content: 71.14

Gene sequence:

>1386_bases
ATGGCTGGCCACGACGCGATTTCGGCCCGCTACCCGCAGGGCCTGCTGTTCCCGGAGGCGGTGATGCGCGAGGTGCGCGG
CCGCTTCCTGCAGGTGGACCACGACCACGCGGGGCGACCGCGGCTGTATTTCGACAACGCGGGCGGCTCCTTCCGCCTGA
AGGCGGCGGTGGAGCGCTTCGCGCAGATCGACGCCGTGCCCGACAACACCGAGCGCATCCACCCCGTCGCGCGCGAGCTG
CAGGCCATCCAGGCCACGGGCACCGACGACCTGCGCATGATGCTCAATGCCGAGGGCGGCAGCGTGCATGCCGCGCTCAC
CGCATCGGGCGCCATGTTCGAGATGGTGCGTGCCATCGCGCTGAACGTGCCGGGCACCAACATGGTCACCACGGTGCTGG
AGCACCCCTCGTCCTACGACGCCATGGAGCGCTATGCGCGCGAGACCGGCCGCGAACTGCGCGTGGCGCCCAGCAATCCG
GCCACGGGCGGGGTGGACGTGGACGCCATCGTGCGGCTGGTGGACGAAGGCACGACGCTGCTGAACGTGATCTACGCCTC
CAACATCTCGGGCGCCAAGCTGGACCTGGAGCGCATCGTGGCCGCGGCCCGCGCCGTGAAGCCCGACCTCTACATCGTGG
TGGATGCCGTGCAGCACGCCCCCCACGGCCTGATCGACCTGCAGAAGACGCCGGTGGACGGCATCAATCTCGCGCCCTAC
AAGTTCTTCGGCTGCCGGGGATCGGGCCTGGCCTGGCTGTCGGACCGCGCGGCCGCGCTGCCGCACCACAAGCTCTCGGC
CAAGCCGGAGGGCTTCTGGGACCTGGGCAGTTCCTCGCCCTGGCAGTTCGCCGTGGTGACCGAGATCGCCGACTACGTCT
GCTGGCTGGGCTGCCAGGCCCTGAAGGAACTGCCGGAGCTGGTCGCCGTGCTGGACGCGGGCGCGGATGCCGGCGAGCCG
CCGCGCCGGGCCCTGTTCGCGGCCGGCATCGAACGCATCATGCTGCACGAGCGCGGCCTGCTGGCGCGCCTGCTGGACGG
CGACGGCGCGGCCCGCCCCGGCCTGCGCGGCATGCCCGGCGTGCAGGTGTTCCTGGACCACCCGGACCTCACCCTGCGCG
ACCTCATCATCGCCATCGGCATCGACGGGGTGGACTGCACCCGGGCCGTGCACGAATACGGCCTGCGCGGCGTGACGGTC
TATGAGCGCAGCGTGGCGAGCCTGTATTCGCGGCGCATGCTCGAATCCTTCGGCCTCGCCGGCGCGGTGCGCGTATCGCC
GCTGCACTGCCATACGGCACAGGACGTGGATGCGTTCCTGCGGGTGACGGAAGACATCGTGCGGGTGCATGCGGCGCTCG
CCACCCGCGAGGCCGCGGCCCTGTAG

Upstream 100 bases:

>100_bases
GGTTCACCCAGCCGATTCCGCCCAACAACGTGAACCTGAACTTCCCGATGACGGACGCCGTGCGCGAGGCCTACCGCAAC
CCCAGCAAGAAGGGCGTGTG

Downstream 100 bases:

>100_bases
CGCGCGGCCCTACAGCCCGCAGTCCACGCCCCAGGCGTGGATGCGCACCACGTCGCAATCCACCTCCGCCGCGATGCGGT
CGGCCACCAGCCAGAGGCCG

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MAGHDAISARYPQGLLFPEAVMREVRGRFLQVDHDHAGRPRLYFDNAGGSFRLKAAVERFAQIDAVPDNTERIHPVAREL
QAIQATGTDDLRMMLNAEGGSVHAALTASGAMFEMVRAIALNVPGTNMVTTVLEHPSSYDAMERYARETGRELRVAPSNP
ATGGVDVDAIVRLVDEGTTLLNVIYASNISGAKLDLERIVAAARAVKPDLYIVVDAVQHAPHGLIDLQKTPVDGINLAPY
KFFGCRGSGLAWLSDRAAALPHHKLSAKPEGFWDLGSSSPWQFAVVTEIADYVCWLGCQALKELPELVAVLDAGADAGEP
PRRALFAAGIERIMLHERGLLARLLDGDGAARPGLRGMPGVQVFLDHPDLTLRDLIIAIGIDGVDCTRAVHEYGLRGVTV
YERSVASLYSRRMLESFGLAGAVRVSPLHCHTAQDVDAFLRVTEDIVRVHAALATREAAAL

Sequences:

>Translated_461_residues
MAGHDAISARYPQGLLFPEAVMREVRGRFLQVDHDHAGRPRLYFDNAGGSFRLKAAVERFAQIDAVPDNTERIHPVAREL
QAIQATGTDDLRMMLNAEGGSVHAALTASGAMFEMVRAIALNVPGTNMVTTVLEHPSSYDAMERYARETGRELRVAPSNP
ATGGVDVDAIVRLVDEGTTLLNVIYASNISGAKLDLERIVAAARAVKPDLYIVVDAVQHAPHGLIDLQKTPVDGINLAPY
KFFGCRGSGLAWLSDRAAALPHHKLSAKPEGFWDLGSSSPWQFAVVTEIADYVCWLGCQALKELPELVAVLDAGADAGEP
PRRALFAAGIERIMLHERGLLARLLDGDGAARPGLRGMPGVQVFLDHPDLTLRDLIIAIGIDGVDCTRAVHEYGLRGVTV
YERSVASLYSRRMLESFGLAGAVRVSPLHCHTAQDVDAFLRVTEDIVRVHAALATREAAAL
>Mature_460_residues
AGHDAISARYPQGLLFPEAVMREVRGRFLQVDHDHAGRPRLYFDNAGGSFRLKAAVERFAQIDAVPDNTERIHPVARELQ
AIQATGTDDLRMMLNAEGGSVHAALTASGAMFEMVRAIALNVPGTNMVTTVLEHPSSYDAMERYARETGRELRVAPSNPA
TGGVDVDAIVRLVDEGTTLLNVIYASNISGAKLDLERIVAAARAVKPDLYIVVDAVQHAPHGLIDLQKTPVDGINLAPYK
FFGCRGSGLAWLSDRAAALPHHKLSAKPEGFWDLGSSSPWQFAVVTEIADYVCWLGCQALKELPELVAVLDAGADAGEPP
RRALFAAGIERIMLHERGLLARLLDGDGAARPGLRGMPGVQVFLDHPDLTLRDLIIAIGIDGVDCTRAVHEYGLRGVTVY
ERSVASLYSRRMLESFGLAGAVRVSPLHCHTAQDVDAFLRVTEDIVRVHAALATREAAAL

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 49807; Mature: 49675

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGHDAISARYPQGLLFPEAVMREVRGRFLQVDHDHAGRPRLYFDNAGGSFRLKAAVERF
CCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCEEHHHHHHHH
AQIDAVPDNTERIHPVARELQAIQATGTDDLRMMLNAEGGSVHAALTASGAMFEMVRAIA
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHH
LNVPGTNMVTTVLEHPSSYDAMERYARETGRELRVAPSNPATGGVDVDAIVRLVDEGTTL
CCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCE
LNVIYASNISGAKLDLERIVAAARAVKPDLYIVVDAVQHAPHGLIDLQKTPVDGINLAPY
EEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCEECCCCCCCCCCCCCE
KFFGCRGSGLAWLSDRAAALPHHKLSAKPEGFWDLGSSSPWQFAVVTEIADYVCWLGCQA
EEECCCCCCCEEECCCHHHCCCCCCCCCCCCCEECCCCCCCEEEHHHHHHHHHHHHHHHH
LKELPELVAVLDAGADAGEPPRRALFAAGIERIMLHERGLLARLLDGDGAARPGLRGMPG
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCC
VQVFLDHPDLTLRDLIIAIGIDGVDCTRAVHEYGLRGVTVYERSVASLYSRRMLESFGLA
CEEEECCCCCHHHHEEHHCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCC
GAVRVSPLHCHTAQDVDAFLRVTEDIVRVHAALATREAAAL
CEEEECCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AGHDAISARYPQGLLFPEAVMREVRGRFLQVDHDHAGRPRLYFDNAGGSFRLKAAVERF
CCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCEEHHHHHHHH
AQIDAVPDNTERIHPVARELQAIQATGTDDLRMMLNAEGGSVHAALTASGAMFEMVRAIA
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHH
LNVPGTNMVTTVLEHPSSYDAMERYARETGRELRVAPSNPATGGVDVDAIVRLVDEGTTL
CCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCE
LNVIYASNISGAKLDLERIVAAARAVKPDLYIVVDAVQHAPHGLIDLQKTPVDGINLAPY
EEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCEECCCCCCCCCCCCCE
KFFGCRGSGLAWLSDRAAALPHHKLSAKPEGFWDLGSSSPWQFAVVTEIADYVCWLGCQA
EEECCCCCCCEEECCCHHHCCCCCCCCCCCCCEECCCCCCCEEEHHHHHHHHHHHHHHHH
LKELPELVAVLDAGADAGEPPRRALFAAGIERIMLHERGLLARLLDGDGAARPGLRGMPG
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCC
VQVFLDHPDLTLRDLIIAIGIDGVDCTRAVHEYGLRGVTVYERSVASLYSRRMLESFGLA
CEEEECCCCCHHHHEEHHCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCC
GAVRVSPLHCHTAQDVDAFLRVTEDIVRVHAALATREAAAL
CEEEECCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7569993; 8253680 [H]