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The map label for this gene is galE [H]

Identifier: 119947079

GI number: 119947079

Start: 4301304

End: 4302326

Strand: Reverse

Name: galE [H]

Synonym: Ping_3477

Alternate gene names: 119947079

Gene position: 4302326-4301304 (Counterclockwise)

Preceding gene: 119947080

Following gene: 119947075

Centisome position: 94.36

GC content: 45.75

Gene sequence:

>1023_bases
ATGAAAATTCTTATTACGGGTGGAATGGGTTATATCGGGAGCCATACTTGTATTCAACTGATGGCTGCGGGCATGACACC
CATTATTCTGGACAATTTATCCAACAGCAGTGAAATCGTATTATCAAGAATCCATCATTTAACTGGCGCTACACCGGTTT
TTTATCAGGGTGATGTGCGCGATCGTCATATTTTAGAAAAAATATTTGCAGAGCATGAAATTGCCGCTGTGATTCACTTT
GCCGGTTTAAAATCCGTTGGCGAATCCGTTGCAAAGCCCCTGGAATATTATGATAACAATGTGCACGGCTCCCTACTGCT
CGCAGAAGTTATGAAAAATGCAGGGGTAAAAAGCCTGTTATTCAGCTCATCGGCCACGGTCTACGGCTCCCCGCTGAAAA
TGCCTATTACTGAATCGACACCAACGGGTGCAACCACTAATCCCTATGGTCGCAGTAAATATATTGTTGAAGAGTGTTTG
CGGGATTTACAAGCGGCACAGCCGGAATTAAGTATCACATTATTACGTTATTTCAATCCCGTTGGCGCCCATATTTCCGG
TACTATCGGCGAGGATCCACAGGGTATTCCGAATAATCTAATGCCTTTTATTGCTCAGGTTGCGGTAGGAAGACGCGAAA
AATTATCTGTATTTGGTAATGATTATAATACCCCCGACGGTACCGGTGTACGTGATTATATCCATGTAATGGACTTGGCC
GACGGACATGTTGCCGCCCTTAAAGCGGTCGGACTTAAACCCGGTCTGCATATCTATAATCTGGGTACAGGCCAAGGCAG
CAGTGTATTAGAGATGGTTGATGCCTTTGCTAAAGCGAGTGGCAAAGAAGTTCCTTATACTGTCTGTGCGCGTCGACCGG
GTGACATTGCCGAATGCTGGGCAGATACTTCCAAAGCCAACCGCGAGCTAAACTGGAAAGCGAGCCGAACATTAAAAGAG
ATGTCCGAGGACAGTTGGCGTTGGCAGTCACAAAACCCTAAGGGTTATGGCAGTCAAGAATAG

Upstream 100 bases:

>100_bases
GCCAATAGACTGCGGTTTTTTTTAATAGATCTATCTTAATCACCGATAGTCTCTATTTTTTGCTGCTAAGATCATTATAT
CAATATTAAGGGAGTTAAAA

Downstream 100 bases:

>100_bases
CAAACTAAGGTTGCGCAGAGCCCTCAATGCACAGTGCTAGAAGGCTTGATGGCTTGAAGGTGGAATGGACAAAATACATC
CTGAGAGTTGAATAAACTTA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKILITGGMGYIGSHTCIQLMAAGMTPIILDNLSNSSEIVLSRIHHLTGATPVFYQGDVRDRHILEKIFAEHEIAAVIHF
AGLKSVGESVAKPLEYYDNNVHGSLLLAEVMKNAGVKSLLFSSSATVYGSPLKMPITESTPTGATTNPYGRSKYIVEECL
RDLQAAQPELSITLLRYFNPVGAHISGTIGEDPQGIPNNLMPFIAQVAVGRREKLSVFGNDYNTPDGTGVRDYIHVMDLA
DGHVAALKAVGLKPGLHIYNLGTGQGSSVLEMVDAFAKASGKEVPYTVCARRPGDIAECWADTSKANRELNWKASRTLKE
MSEDSWRWQSQNPKGYGSQE

Sequences:

>Translated_340_residues
MKILITGGMGYIGSHTCIQLMAAGMTPIILDNLSNSSEIVLSRIHHLTGATPVFYQGDVRDRHILEKIFAEHEIAAVIHF
AGLKSVGESVAKPLEYYDNNVHGSLLLAEVMKNAGVKSLLFSSSATVYGSPLKMPITESTPTGATTNPYGRSKYIVEECL
RDLQAAQPELSITLLRYFNPVGAHISGTIGEDPQGIPNNLMPFIAQVAVGRREKLSVFGNDYNTPDGTGVRDYIHVMDLA
DGHVAALKAVGLKPGLHIYNLGTGQGSSVLEMVDAFAKASGKEVPYTVCARRPGDIAECWADTSKANRELNWKASRTLKE
MSEDSWRWQSQNPKGYGSQE
>Mature_340_residues
MKILITGGMGYIGSHTCIQLMAAGMTPIILDNLSNSSEIVLSRIHHLTGATPVFYQGDVRDRHILEKIFAEHEIAAVIHF
AGLKSVGESVAKPLEYYDNNVHGSLLLAEVMKNAGVKSLLFSSSATVYGSPLKMPITESTPTGATTNPYGRSKYIVEECL
RDLQAAQPELSITLLRYFNPVGAHISGTIGEDPQGIPNNLMPFIAQVAVGRREKLSVFGNDYNTPDGTGVRDYIHVMDLA
DGHVAALKAVGLKPGLHIYNLGTGQGSSVLEMVDAFAKASGKEVPYTVCARRPGDIAECWADTSKANRELNWKASRTLKE
MSEDSWRWQSQNPKGYGSQE

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=344, Percent_Identity=57.5581395348837, Blast_Score=420, Evalue=1e-118,
Organism=Homo sapiens, GI56118217, Length=344, Percent_Identity=57.5581395348837, Blast_Score=420, Evalue=1e-118,
Organism=Homo sapiens, GI189083684, Length=344, Percent_Identity=57.5581395348837, Blast_Score=420, Evalue=1e-118,
Organism=Homo sapiens, GI7657641, Length=275, Percent_Identity=28.3636363636364, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI42516563, Length=326, Percent_Identity=26.0736196319018, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=63.0952380952381, Blast_Score=452, Evalue=1e-128,
Organism=Escherichia coli, GI1788353, Length=364, Percent_Identity=25.5494505494505, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI48994969, Length=364, Percent_Identity=26.0989010989011, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=348, Percent_Identity=50.8620689655172, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI71982038, Length=350, Percent_Identity=50.5714285714286, Blast_Score=361, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17568069, Length=345, Percent_Identity=24.9275362318841, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=50.7288629737609, Blast_Score=347, Evalue=2e-96,
Organism=Drosophila melanogaster, GI19923002, Length=345, Percent_Identity=54.2028985507246, Blast_Score=389, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36936; Mature: 36936

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILITGGMGYIGSHTCIQLMAAGMTPIILDNLSNSSEIVLSRIHHLTGATPVFYQGDVR
CEEEEECCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCC
DRHILEKIFAEHEIAAVIHFAGLKSVGESVAKPLEYYDNNVHGSLLLAEVMKNAGVKSLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHH
FSSSATVYGSPLKMPITESTPTGATTNPYGRSKYIVEECLRDLQAAQPELSITLLRYFNP
HCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHCC
VGAHISGTIGEDPQGIPNNLMPFIAQVAVGRREKLSVFGNDYNTPDGTGVRDYIHVMDLA
CCCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCC
DGHVAALKAVGLKPGLHIYNLGTGQGSSVLEMVDAFAKASGKEVPYTVCARRPGDIAECW
CCHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHH
ADTSKANRELNWKASRTLKEMSEDSWRWQSQNPKGYGSQE
HHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKILITGGMGYIGSHTCIQLMAAGMTPIILDNLSNSSEIVLSRIHHLTGATPVFYQGDVR
CEEEEECCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCC
DRHILEKIFAEHEIAAVIHFAGLKSVGESVAKPLEYYDNNVHGSLLLAEVMKNAGVKSLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHH
FSSSATVYGSPLKMPITESTPTGATTNPYGRSKYIVEECLRDLQAAQPELSITLLRYFNP
HCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHCC
VGAHISGTIGEDPQGIPNNLMPFIAQVAVGRREKLSVFGNDYNTPDGTGVRDYIHVMDLA
CCCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCC
DGHVAALKAVGLKPGLHIYNLGTGQGSSVLEMVDAFAKASGKEVPYTVCARRPGDIAECW
CCHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHH
ADTSKANRELNWKASRTLKEMSEDSWRWQSQNPKGYGSQE
HHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]