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The map label for this gene is galE [H]

Identifier: 119947059

GI number: 119947059

Start: 4275862

End: 4277388

Strand: Reverse

Name: galE [H]

Synonym: Ping_3457

Alternate gene names: 119947059

Gene position: 4277388-4275862 (Counterclockwise)

Preceding gene: 119947060

Following gene: 119947058

Centisome position: 93.81

GC content: 39.49

Gene sequence:

>1527_bases
ATGAAAATAGTATTAACAGGCTCTACAGGTTTTCTTGGTAAGGAGTTATTAACTAAACTTGCAAATGAGCCTGTTGAATT
AATTCAAATTGGCCGTAACGAATATAACAAAAATAATCCTCATTATATTTATATCAAGGGTCTTGATTCAGCTTCTCAGT
TTAATTTAGCCATTTATAAATGTGATGTTGTCATCCATTGCGCTGCCCGTGTGCATATTATGGATGATGATTCAGCTAAT
CCATTAGAAGATTTTCGTGAAGTAAATAGCCACGGCACACTCAACCTTGCTCAGCAGGCTGCGGATGCCGGGGTTAAACG
TTTTATTTTTATTAGCTCTATTAAAGTAAACGGTGAATCTACCGAAACGGTTGCCCCTTTCAAACCTGATACTGATTTTG
TCCCGACTGATCCCTACGGGCTGAGTAAATATGAGGCAGAAGTGGGTTTACGCAAAATAGCAGAACAGACCGGCATGGAG
GTAGTGATTATTCGTCCTACTTTGGTTTATGGTCCGGGAGTTAAAGCTAATTTTGCAGCAATGATGAAATGGGTGAATAA
AGGCGTTCCTCTGCCTTTAGGTGGTATTACCGATAATCGACGCAGTTTAGTATCAATAGATAATTTGGTTGATTTAATTA
TCATTTGCATTGAACACCCGAATGCAGCGAATCAAACATTTTTAGTCTCCGATGATGATGATATGTCGACATCTAAATTA
CTTGTCCGTATGGCGACCGCATTGGATGTGCCCAATAGAATGTTACCTATTTCGAGTTCCTGGTTGACGTTAGCAGCTAA
GTTAATTGGAAAACCGGCAACAGCACAGCGGCTATGTGGCTCTTTGCAGGTTGATATATCTCAAACTAAAGAACTGTTAA
ACTGGAAGCCGCCCTACAGCACTCCTGAATGTTTAAAAAAAACAGCGGATGCTTTTCTTTATACCTCTGCACAAGTCACA
AATAATATGAATTCTTTTACCATTCGAACATTAGATTTTTTAATGGCTTTTTTGGGCCTGTTCGTCACTTTCCCCATTTT
ATTGATCGTTACTATTATCGGTTATTTTGATACTGGTGCGCCTATTTTTATTCAGCAGCGTGTGGGCAAAAATAAACGCC
CATTTAACTTAATTAAATTCCGTACTATGTCGGTTGATACCAAGTCGGTTGCCAGCCATTTAGCAAGCACTGCTTCAATT
ACTAAGCTAGGTTCTTTTTTACGTAAATCAAAATTTGATGAGATTCCACAGTTAATTAATGTGCTGAAGGGGGAGATGAG
TTTTGTCGGGCCTCGCCCTAACTTGTTTAATCAGGGAGCGTTAATTATCGAGCGTGAGAGTCGTGGCGTGTACGATGTTT
TGCCTGGTATTACTGGCCTTGCGCAGGTGAATACTATCGATATGTCAACGCCTCAATTATTGGCTGAAACCGATCAAAAA
ATGATTCAAACCATCACTCTTAAAAACTATTTCCAATACATTATTAAAACAGCAACAGGCAGTGGTTCGGGTGATCGGGT
GAAATAG

Upstream 100 bases:

>100_bases
AAGGTGCATACAAAAATAGAAAACTATTTTCTAAACATTTTAGATGGTATTTTTCGAGCCTGCTGAGATTCCTATTTAAA
AGCACTTTCGAGACTAAAAG

Downstream 100 bases:

>100_bases
TTCTTTATTGATGACTACTCTCTCAACCGCTGAGCCCAAAGGCTCATGTCCAAAACCAACTCCTGCAAAACCAACTCCTG
AAAGATGAGTGCCAAAAAAT

Product: nucleoside-diphosphate-sugar epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MKIVLTGSTGFLGKELLTKLANEPVELIQIGRNEYNKNNPHYIYIKGLDSASQFNLAIYKCDVVIHCAARVHIMDDDSAN
PLEDFREVNSHGTLNLAQQAADAGVKRFIFISSIKVNGESTETVAPFKPDTDFVPTDPYGLSKYEAEVGLRKIAEQTGME
VVIIRPTLVYGPGVKANFAAMMKWVNKGVPLPLGGITDNRRSLVSIDNLVDLIIICIEHPNAANQTFLVSDDDDMSTSKL
LVRMATALDVPNRMLPISSSWLTLAAKLIGKPATAQRLCGSLQVDISQTKELLNWKPPYSTPECLKKTADAFLYTSAQVT
NNMNSFTIRTLDFLMAFLGLFVTFPILLIVTIIGYFDTGAPIFIQQRVGKNKRPFNLIKFRTMSVDTKSVASHLASTASI
TKLGSFLRKSKFDEIPQLINVLKGEMSFVGPRPNLFNQGALIIERESRGVYDVLPGITGLAQVNTIDMSTPQLLAETDQK
MIQTITLKNYFQYIIKTATGSGSGDRVK

Sequences:

>Translated_508_residues
MKIVLTGSTGFLGKELLTKLANEPVELIQIGRNEYNKNNPHYIYIKGLDSASQFNLAIYKCDVVIHCAARVHIMDDDSAN
PLEDFREVNSHGTLNLAQQAADAGVKRFIFISSIKVNGESTETVAPFKPDTDFVPTDPYGLSKYEAEVGLRKIAEQTGME
VVIIRPTLVYGPGVKANFAAMMKWVNKGVPLPLGGITDNRRSLVSIDNLVDLIIICIEHPNAANQTFLVSDDDDMSTSKL
LVRMATALDVPNRMLPISSSWLTLAAKLIGKPATAQRLCGSLQVDISQTKELLNWKPPYSTPECLKKTADAFLYTSAQVT
NNMNSFTIRTLDFLMAFLGLFVTFPILLIVTIIGYFDTGAPIFIQQRVGKNKRPFNLIKFRTMSVDTKSVASHLASTASI
TKLGSFLRKSKFDEIPQLINVLKGEMSFVGPRPNLFNQGALIIERESRGVYDVLPGITGLAQVNTIDMSTPQLLAETDQK
MIQTITLKNYFQYIIKTATGSGSGDRVK
>Mature_508_residues
MKIVLTGSTGFLGKELLTKLANEPVELIQIGRNEYNKNNPHYIYIKGLDSASQFNLAIYKCDVVIHCAARVHIMDDDSAN
PLEDFREVNSHGTLNLAQQAADAGVKRFIFISSIKVNGESTETVAPFKPDTDFVPTDPYGLSKYEAEVGLRKIAEQTGME
VVIIRPTLVYGPGVKANFAAMMKWVNKGVPLPLGGITDNRRSLVSIDNLVDLIIICIEHPNAANQTFLVSDDDDMSTSKL
LVRMATALDVPNRMLPISSSWLTLAAKLIGKPATAQRLCGSLQVDISQTKELLNWKPPYSTPECLKKTADAFLYTSAQVT
NNMNSFTIRTLDFLMAFLGLFVTFPILLIVTIIGYFDTGAPIFIQQRVGKNKRPFNLIKFRTMSVDTKSVASHLASTASI
TKLGSFLRKSKFDEIPQLINVLKGEMSFVGPRPNLFNQGALIIERESRGVYDVLPGITGLAQVNTIDMSTPQLLAETDQK
MIQTITLKNYFQYIIKTATGSGSGDRVK

Specific function: Slime polysaccharide colanic acid biosynthesis. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7657641, Length=187, Percent_Identity=31.0160427807487, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI1788360, Length=154, Percent_Identity=35.7142857142857, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 56013; Mature: 56013

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVLTGSTGFLGKELLTKLANEPVELIQIGRNEYNKNNPHYIYIKGLDSASQFNLAIYK
CEEEEECCCCCHHHHHHHHHCCCCHHHHHHCCHHCCCCCCEEEEEEECCCCCCCEEEEEE
CDVVIHCAARVHIMDDDSANPLEDFREVNSHGTLNLAQQAADAGVKRFIFISSIKVNGES
EEEEEEEEEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEEEEEECCCC
TETVAPFKPDTDFVPTDPYGLSKYEAEVGLRKIAEQTGMEVVIIRPTLVYGPGVKANFAA
CCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECEEEECCCCCHHHHH
MMKWVNKGVPLPLGGITDNRRSLVSIDNLVDLIIICIEHPNAANQTFLVSDDDDMSTSKL
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCEEEEECCCCCHHHHH
LVRMATALDVPNRMLPISSSWLTLAAKLIGKPATAQRLCGSLQVDISQTKELLNWKPPYS
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCEEECHHHHHHHHCCCCCCC
TPECLKKTADAFLYTSAQVTNNMNSFTIRTLDFLMAFLGLFVTFPILLIVTIIGYFDTGA
CHHHHHHHHHHHEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PIFIQQRVGKNKRPFNLIKFRTMSVDTKSVASHLASTASITKLGSFLRKSKFDEIPQLIN
CEEEEHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLKGEMSFVGPRPNLFNQGALIIERESRGVYDVLPGITGLAQVNTIDMSTPQLLAETDQK
HHHCHHHCCCCCCCCCCCCEEEEEECCCCHHHHHCCCCCCCEEEEECCCCHHHHHHHHHH
MIQTITLKNYFQYIIKTATGSGSGDRVK
HHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKIVLTGSTGFLGKELLTKLANEPVELIQIGRNEYNKNNPHYIYIKGLDSASQFNLAIYK
CEEEEECCCCCHHHHHHHHHCCCCHHHHHHCCHHCCCCCCEEEEEEECCCCCCCEEEEEE
CDVVIHCAARVHIMDDDSANPLEDFREVNSHGTLNLAQQAADAGVKRFIFISSIKVNGES
EEEEEEEEEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEEEEEECCCC
TETVAPFKPDTDFVPTDPYGLSKYEAEVGLRKIAEQTGMEVVIIRPTLVYGPGVKANFAA
CCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECEEEECCCCCHHHHH
MMKWVNKGVPLPLGGITDNRRSLVSIDNLVDLIIICIEHPNAANQTFLVSDDDDMSTSKL
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCEEEEECCCCCHHHHH
LVRMATALDVPNRMLPISSSWLTLAAKLIGKPATAQRLCGSLQVDISQTKELLNWKPPYS
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCEEECHHHHHHHHCCCCCCC
TPECLKKTADAFLYTSAQVTNNMNSFTIRTLDFLMAFLGLFVTFPILLIVTIIGYFDTGA
CHHHHHHHHHHHEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PIFIQQRVGKNKRPFNLIKFRTMSVDTKSVASHLASTASITKLGSFLRKSKFDEIPQLIN
CEEEEHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLKGEMSFVGPRPNLFNQGALIIERESRGVYDVLPGITGLAQVNTIDMSTPQLLAETDQK
HHHCHHHCCCCCCCCCCCCEEEEEECCCCHHHHHCCCCCCCEEEEECCCCHHHHHHHHHH
MIQTITLKNYFQYIIKTATGSGSGDRVK
HHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8820651; 10521656 [H]