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The map label for this gene is rpoC

Identifier: 119947048

GI number: 119947048

Start: 4255946

End: 4260166

Strand: Reverse

Name: rpoC

Synonym: Ping_3445

Alternate gene names: 119947048

Gene position: 4260166-4255946 (Counterclockwise)

Preceding gene: 119947049

Following gene: 119947047

Centisome position: 93.43

GC content: 43.8

Gene sequence:

>4221_bases
GTGAAAGACTTATTAAAGTTTTTAAAGCAGCAAAATAAAACCAAAGAATTTGATGGTATTAAAATTGGTTTAGCATCACC
TGAAATGGTCCGCTCATGGTCATTTGGTGAAGTTAAAAAACCAGAAACAATTAACTACCGTACCTTTAAACCTGAACGTG
AAGGTTTATTCTGTGCGCGTATCTTTGGTCCAATCAAAGATTACGAATGTTTATGTGGCAAGTATAAACGCCTGAAACAT
CGTGGTGTTATTTGTGAAAAATGTGGTGTTGAGGTAACTCAGTCTAAAGTTCGTCGTGACCGTATGGGCCATATCGAATT
AGCATCCCCTGTCGCTCACATTTGGTTCCTTAAATCATTACCGTCTCGTATCGGCTTAATGCTTGATATGACCCTGCGTG
ATATTGAACGTATCCTCTATTTTGAATCTTTCGTGGTGGTTGAACCCGGCATGACAGATCTTGAGCGTCGTCAAATTCTT
CTTGAAGAAGAATATTTAGACATGCTTGAGCAGTGGGGCGATGAGTTTGAAGCTGTAATGGGCGCAGAAGCTATCTTCTC
GCTATTAAAACAGCTGGATCTCGATCATGAGATTGCTGAAATGCGTGAAGAGTTGGGGACTACTAACTCTGAGACTAAGC
GTAAAAAATTAACTAAACGTCTGAAACTGGTTGAGTCTTTCCACCAGTCTTCAAACAAACCCGAGTGGATGATCCTGACT
GTATTGCCAGTGCTTCCGCCGGATTTACGTCCGCTTGTGCCACTTGATGGCGGTCGTTTTGCGACATCGGATCTAAATGA
CTTATACCGTCGTGTTATTAACCGTAATAACCGTCTAAAACGCCTACTAGATTTAGCGGCGCCAGATATCATCGTACGCA
ACGAAAAGCGTATGTTACAAGAGTCTGTGGATGCATTATTAGACAATGGTCGTCGTGGTCGTGCTATTACAGGTTCTAAC
AAGCGTCCTCTGAAATCACTTGCTGATATGATCAAAGGTAAACAGGGTCGTTTCCGTCAGAATCTACTCGGTAAGCGTGT
AGATTACTCCGGCCGTTCTGTAATTACAGTAGGACCGACACTGCGTTTACACCAGTGTGGTCTTCCTAAGAAAATGGCAC
TTGAACTGTTCAAGCCCTTTGTTTACGGAAAACTGGAAGCATTAGGTCTTGCGACGACTATTAAAGCGGCTAAAAAGCTT
GTTGATCGTGAAGGTGGTGAAGTTTGGGACATTCTGGAAGGCGTGATTCGCGAACATCCAGTACTGCTTAACCGTGCACC
CACACTGCACAGATTGGGTATCCAGGCATTTGAACCCGTACTGATTGAAGGTAAAGCGATTCAGCTTCACCCGCTGGTTT
GTGCGGCATACAACGCCGATTTCGATGGTGACCAAATGGCGGTACACGTACCGTTAACTATTGAAGCACAGCTTGAAGCT
CGTACTCTGATGATGTCGACCAATAACATCCTATCGCCAGCAAATGGTGAGCCGATTATTGTTCCTTCTCAAGATGTTGT
ACTTGGCCTTTATTACATGACTCGTTCTAAGATAAATTCATTAGGCGAAGACATGTGGTTCCAAAGCGCGAAAGAAGCAG
AAAAAGCGTATCGTGCCGGTGCTGTTGGTTTACAAGCTATTGTTAAAGTACGTATGAAACAAGTTCATATTGCTGATGAC
AAGAGCCGTACAGAAACAACTAATATTATCGAAACAACCGTTGGCCGTGCGATTTTATCGTTAATTATGCCAGAAGGTCT
GCCCTTTGAGCTTGTTGATTTACCCATGGGTAAAAAGCAAATATCGACTGCACTGAATGCCTGTTACCGTCTATTGGGTA
TTAAGCATACGGTTATTTTTGCTGACCAATTAATGTATACCGGTTTTGAATATGCAACCTTGTCAGGTGCTTCGGTATGT
ATCGACGATATGGTTATTCCTACTACTAAGAAAACCTTAGTTGAAGCTGCTGAAGCTGAAGTTCAGGAAATTCACGAACA
GTTCCAGGCAGGTCTTGTAACTGCCGGTGAGCGCTACAACAAAGTTATCGATATCTGGGCAAGTGCGAATGAGCAGGTTG
CCAAAGCGATGATGGAAAACCTTTCTAAAGATACTGTTGTTAATAGCAAAGGTGAAGAAGTTCAACAAGATTCGTTTAAC
AGCGTTTACATGATGGCCGACTCAGGTGCACGTGGTAGTGCTGCACAGATTCGTCAGTTAGCGGGTATGCGTGGTTTGAT
GGCTAAACCCGATGGTTCAATCATCGAAACGCCGATCACAGCGAACTTCCGTGAAGGTCTAAACGTACTTCAGTACTTTA
TCTCCACGCACGGTGCACGTAAAGGTCTGGCCGATACCGCACTTAAAACAGCAAACTCGGGTTATCTAACGCGTCGTCTT
GTTGATATCGCGCAAGATCTAGTTATCACTGAAAAAGATTGTGGTAGTGAAGATGGTCTGCTAGTTACACCGCTTATCCA
GGGTGGTGATGTTGTTGAAGCACTTCGTGAGCGTGTGCTTGGTCGTGTTGTGGCTCAAGACATCATTAAACCGGGAACCA
AGGGCGAAGTCCTAATTGCCCGTAATGTTCTGCTTGATGAAAAACTATGTGACCTTATCGAAGAAGCATCTGTTGACCAA
GTTTGGGTACGTTCAGTTATCACTTGTCAAACAGACTTTGGTGCTTGTGCACAATGTTACGGCCGTGACCTTGCTCGTGG
CCATATGGTCGGTCAAGGTGAAGCAATCGGTGTTATGGCAGCGCAATCAATCGGTGAGCCAGGAACACAGCTTACAATGC
GTACCTTCCACATCGGTGGTGCTGCATCTCGTGCCGCTTCTGAAAACAATATTCAGGTTAAGAATACGGGTAAAATCAAA
CTGCATAACGCTAAGTTTGTAATTAACTCTGAGCAGAAAGTAGTTGTTACTTCCCGTTCAACAGAATTAACTATTATTGA
TAAATTAGGCCGTACTAAAGAAAACCATAGACTGCCTTACGGTGCCGTTCTTGAGAAACAAGATGGTGCTGAAATCACCT
CTGGTGAAATCATCGCTAACTGGGACCCGCATACACATCCAATTATTACGGAAGTGGAAGGTACTGTTCAGTTCTTGGAC
TTTATCGAAGGTCTGAGCATTACTAAACAAGCTGATGAATTTACCGGTTTATCAAGTACTGTTATTATTGATCCGGCACA
GCGACCTAATGCTGGTAAAGAATTGCGTCCGATGGTTAAACTTGTCGATCCACAGGGTAATGACTTGTTTATTCCCGGGA
CAGATGTTGCGGCTCAATATGCACTTGCTGCAAACGCCATCGTTAGTCTTGAAGATGGTGCAAAAGTACGAGTGGGTGAT
GCGGTTGCACGTATTCCTCAAGAAAGCTCAAAAACACGTGACATCACGGGTGGTTTACCACGCGTTGCCGATCTGTTTGA
AGCGCGTACGCCAAAAGATGCAGCCATTCTTGCAGAAGTTTCTGGTACGCTTGCATTTGGTAAAGAGACTAAAGGCAAAC
GCCGCTTAGTTATTACCCAGGCAAACGGTGAAGCTTATGAAGAAATGGTGCCTAAATGGCGTCACCTGAACATCTTCGAA
GGTGAGAAGATTGAAAAAGGTGAGGTTATTTCTGATGGTCCTGAATCACCACATGATATTCTTCGTTTACGTGGTATTAG
CCCGGTTGCTAACTACATCACTAATGAAGTACAGGAAGTTTACCGCTTACAGGGCGTAAAAATTAATGATAAACACATTG
AAGTTATCGTTAACCAAATGCTACGTAAAGGTACAATTACTGATAATGGTGATTCTGCATTCTTAGTAGGCGAACAGGCT
GAAGTTGCACGTGTTGTGATTGAAAACCGCCGCCTGGTAGCCGAAGGTAAAGCAATTGCTACTTTTGATTATCAATTATT
AGGTATCACGAAAGCATCTCTGGCAACTGAGTCGTTTATCTCAGCCGCATCTTTCCAAGAAACAACACGGGTTCTTACGG
AAGCTGCTGTTGCCGGCAAGTGTGATCAATTACACGGCCTGAAAGAGAATGTTATCGTTGGTCGTCTGATTCCTGCCGGT
ACTGGTTTCGCTCATCATAGAGCAAGGGCCGCTGCGAAAGCTGCTGAACTGGCACCAAAAGTTGAAGAAACAATTGTAGA
TACGGGTACAGCTGAACAAAACTTAGCTGACTTGCTAAATGCTGTTGATTTTGGTGATTAA

Upstream 100 bases:

>100_bases
AACATTGAACTAGATGAAAGTAACTAAGCATTAAGCTGTAGTAAATATGTGGCGTCTTGAAAATTAAGGCGCCTAGTTTT
AACTCCTATGGGAGAGTAGC

Downstream 100 bases:

>100_bases
TCACTAATTTCATCGTCTATAAAAAAGGTGCTTCGGCACCTTTTTTTTGTATCTGGGATACAGCTTTCGGCCGTTAGCTG
TCGGCTGTCAGTTAGCCTCT

Product: DNA-directed RNA polymerase, beta' subunit

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1406; Mature: 1406

Protein sequence:

>1406_residues
MKDLLKFLKQQNKTKEFDGIKIGLASPEMVRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTQSKVRRDRMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERILYFESFVVVEPGMTDLERRQIL
LEEEYLDMLEQWGDEFEAVMGAEAIFSLLKQLDLDHEIAEMREELGTTNSETKRKKLTKRLKLVESFHQSSNKPEWMILT
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFVYGKLEALGLATTIKAAKKL
VDREGGEVWDILEGVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTIEAQLEA
RTLMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRSKINSLGEDMWFQSAKEAEKAYRAGAVGLQAIVKVRMKQVHIADD
KSRTETTNIIETTVGRAILSLIMPEGLPFELVDLPMGKKQISTALNACYRLLGIKHTVIFADQLMYTGFEYATLSGASVC
IDDMVIPTTKKTLVEAAEAEVQEIHEQFQAGLVTAGERYNKVIDIWASANEQVAKAMMENLSKDTVVNSKGEEVQQDSFN
SVYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDIAQDLVITEKDCGSEDGLLVTPLIQGGDVVEALRERVLGRVVAQDIIKPGTKGEVLIARNVLLDEKLCDLIEEASVDQ
VWVRSVITCQTDFGACAQCYGRDLARGHMVGQGEAIGVMAAQSIGEPGTQLTMRTFHIGGAASRAASENNIQVKNTGKIK
LHNAKFVINSEQKVVVTSRSTELTIIDKLGRTKENHRLPYGAVLEKQDGAEITSGEIIANWDPHTHPIITEVEGTVQFLD
FIEGLSITKQADEFTGLSSTVIIDPAQRPNAGKELRPMVKLVDPQGNDLFIPGTDVAAQYALAANAIVSLEDGAKVRVGD
AVARIPQESSKTRDITGGLPRVADLFEARTPKDAAILAEVSGTLAFGKETKGKRRLVITQANGEAYEEMVPKWRHLNIFE
GEKIEKGEVISDGPESPHDILRLRGISPVANYITNEVQEVYRLQGVKINDKHIEVIVNQMLRKGTITDNGDSAFLVGEQA
EVARVVIENRRLVAEGKAIATFDYQLLGITKASLATESFISAASFQETTRVLTEAAVAGKCDQLHGLKENVIVGRLIPAG
TGFAHHRARAAAKAAELAPKVEETIVDTGTAEQNLADLLNAVDFGD

Sequences:

>Translated_1406_residues
MKDLLKFLKQQNKTKEFDGIKIGLASPEMVRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTQSKVRRDRMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERILYFESFVVVEPGMTDLERRQIL
LEEEYLDMLEQWGDEFEAVMGAEAIFSLLKQLDLDHEIAEMREELGTTNSETKRKKLTKRLKLVESFHQSSNKPEWMILT
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFVYGKLEALGLATTIKAAKKL
VDREGGEVWDILEGVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTIEAQLEA
RTLMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRSKINSLGEDMWFQSAKEAEKAYRAGAVGLQAIVKVRMKQVHIADD
KSRTETTNIIETTVGRAILSLIMPEGLPFELVDLPMGKKQISTALNACYRLLGIKHTVIFADQLMYTGFEYATLSGASVC
IDDMVIPTTKKTLVEAAEAEVQEIHEQFQAGLVTAGERYNKVIDIWASANEQVAKAMMENLSKDTVVNSKGEEVQQDSFN
SVYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDIAQDLVITEKDCGSEDGLLVTPLIQGGDVVEALRERVLGRVVAQDIIKPGTKGEVLIARNVLLDEKLCDLIEEASVDQ
VWVRSVITCQTDFGACAQCYGRDLARGHMVGQGEAIGVMAAQSIGEPGTQLTMRTFHIGGAASRAASENNIQVKNTGKIK
LHNAKFVINSEQKVVVTSRSTELTIIDKLGRTKENHRLPYGAVLEKQDGAEITSGEIIANWDPHTHPIITEVEGTVQFLD
FIEGLSITKQADEFTGLSSTVIIDPAQRPNAGKELRPMVKLVDPQGNDLFIPGTDVAAQYALAANAIVSLEDGAKVRVGD
AVARIPQESSKTRDITGGLPRVADLFEARTPKDAAILAEVSGTLAFGKETKGKRRLVITQANGEAYEEMVPKWRHLNIFE
GEKIEKGEVISDGPESPHDILRLRGISPVANYITNEVQEVYRLQGVKINDKHIEVIVNQMLRKGTITDNGDSAFLVGEQA
EVARVVIENRRLVAEGKAIATFDYQLLGITKASLATESFISAASFQETTRVLTEAAVAGKCDQLHGLKENVIVGRLIPAG
TGFAHHRARAAAKAAELAPKVEETIVDTGTAEQNLADLLNAVDFGD
>Mature_1406_residues
MKDLLKFLKQQNKTKEFDGIKIGLASPEMVRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTQSKVRRDRMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERILYFESFVVVEPGMTDLERRQIL
LEEEYLDMLEQWGDEFEAVMGAEAIFSLLKQLDLDHEIAEMREELGTTNSETKRKKLTKRLKLVESFHQSSNKPEWMILT
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFVYGKLEALGLATTIKAAKKL
VDREGGEVWDILEGVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTIEAQLEA
RTLMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRSKINSLGEDMWFQSAKEAEKAYRAGAVGLQAIVKVRMKQVHIADD
KSRTETTNIIETTVGRAILSLIMPEGLPFELVDLPMGKKQISTALNACYRLLGIKHTVIFADQLMYTGFEYATLSGASVC
IDDMVIPTTKKTLVEAAEAEVQEIHEQFQAGLVTAGERYNKVIDIWASANEQVAKAMMENLSKDTVVNSKGEEVQQDSFN
SVYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDIAQDLVITEKDCGSEDGLLVTPLIQGGDVVEALRERVLGRVVAQDIIKPGTKGEVLIARNVLLDEKLCDLIEEASVDQ
VWVRSVITCQTDFGACAQCYGRDLARGHMVGQGEAIGVMAAQSIGEPGTQLTMRTFHIGGAASRAASENNIQVKNTGKIK
LHNAKFVINSEQKVVVTSRSTELTIIDKLGRTKENHRLPYGAVLEKQDGAEITSGEIIANWDPHTHPIITEVEGTVQFLD
FIEGLSITKQADEFTGLSSTVIIDPAQRPNAGKELRPMVKLVDPQGNDLFIPGTDVAAQYALAANAIVSLEDGAKVRVGD
AVARIPQESSKTRDITGGLPRVADLFEARTPKDAAILAEVSGTLAFGKETKGKRRLVITQANGEAYEEMVPKWRHLNIFE
GEKIEKGEVISDGPESPHDILRLRGISPVANYITNEVQEVYRLQGVKINDKHIEVIVNQMLRKGTITDNGDSAFLVGEQA
EVARVVIENRRLVAEGKAIATFDYQLLGITKASLATESFISAASFQETTRVLTEAAVAGKCDQLHGLKENVIVGRLIPAG
TGFAHHRARAAAKAAELAPKVEETIVDTGTAEQNLADLLNAVDFGD

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=917, Percent_Identity=25.6270447110142, Blast_Score=189, Evalue=2e-47,
Organism=Homo sapiens, GI39725938, Length=348, Percent_Identity=32.183908045977, Blast_Score=137, Evalue=9e-32,
Organism=Homo sapiens, GI103471997, Length=223, Percent_Identity=30.4932735426009, Blast_Score=91, Evalue=9e-18,
Organism=Escherichia coli, GI2367335, Length=1402, Percent_Identity=75.6062767475036, Blast_Score=2187, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=880, Percent_Identity=25.5681818181818, Blast_Score=186, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI71987878, Length=565, Percent_Identity=24.7787610619469, Blast_Score=154, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6320061, Length=922, Percent_Identity=25.1626898047722, Blast_Score=184, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6324690, Length=690, Percent_Identity=25.7971014492754, Blast_Score=167, Evalue=8e-42,
Organism=Drosophila melanogaster, GI17530899, Length=657, Percent_Identity=26.9406392694064, Blast_Score=177, Evalue=4e-44,
Organism=Drosophila melanogaster, GI281360912, Length=501, Percent_Identity=24.9500998003992, Blast_Score=134, Evalue=4e-31,
Organism=Drosophila melanogaster, GI17647875, Length=328, Percent_Identity=28.3536585365854, Blast_Score=102, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_PSYIN (A1T064)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944728.1
- ProteinModelPortal:   A1T064
- STRING:   A1T064
- GeneID:   4625599
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_3445
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- PhylomeDB:   A1T064
- BioCyc:   PING357804:PING_3445-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 155106; Mature: 155106

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLLKFLKQQNKTKEFDGIKIGLASPEMVRSWSFGEVKKPETINYRTFKPEREGLFCAR
CHHHHHHHHHCCCCCCCCCEEEECCCHHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTQSKVRRDRMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRIGLMLDMTLRDIERILYFESFVVVEPGMTDLERRQILLEEEYLDMLEQWGDEFEAVM
HHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHH
GAEAIFSLLKQLDLDHEIAEMREELGTTNSETKRKKLTKRLKLVESFHQSSNKPEWMILT
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHH
ESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPT
HHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCC
LRLHQCGLPKKMALELFKPFVYGKLEALGLATTIKAAKKLVDREGGEVWDILEGVIREHP
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
VLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTIEAQLEA
EEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEEEEEEEEEECCCE
RTLMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRSKINSLGEDMWFQSAKEAEKAYRAG
EEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGLQAIVKVRMKQVHIADDKSRTETTNIIETTVGRAILSLIMPEGLPFELVDLPMGKKQ
HHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHH
ISTALNACYRLLGIKHTVIFADQLMYTGFEYATLSGASVCIDDMVIPTTKKTLVEAAEAE
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEECCCCCEECCCEECCCCHHHHHHHHHHH
VQEIHEQFQAGLVTAGERYNKVIDIWASANEQVAKAMMENLSKDTVVNSKGEEVQQDSFN
HHHHHHHHHCCCHHCCHHHCCEEEEECCCCHHHHHHHHHHCCCCCEECCCCCHHHHCCCC
SVYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
KGLADTALKTANSGYLTRRLVDIAQDLVITEKDCGSEDGLLVTPLIQGGDVVEALRERVL
CCHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHH
GRVVAQDIIKPGTKGEVLIARNVLLDEKLCDLIEEASVDQVWVRSVITCQTDFGACAQCY
HHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHH
GRDLARGHMVGQGEAIGVMAAQSIGEPGTQLTMRTFHIGGAASRAASENNIQVKNTGKIK
CCHHHCCCCCCCCCEEEEEEHHHCCCCCCEEEEEEEEECCHHHHCCCCCCEEEEECCEEE
LHNAKFVINSEQKVVVTSRSTELTIIDKLGRTKENHRLPYGAVLEKQDGAEITSGEIIAN
EECEEEEECCCCEEEEEECCCEEEEEHHHCCCCCCCCCCCHHEEECCCCCCCCCCCEEEC
WDPHTHPIITEVEGTVQFLDFIEGLSITKQADEFTGLSSTVIIDPAQRPNAGKELRPMVK
CCCCCCCEEEECHHHHHHHHHHCCCCHHCCHHHHCCCCCEEEECCCCCCCCCHHHHHHHH
LVDPQGNDLFIPGTDVAAQYALAANAIVSLEDGAKVRVGDAVARIPQESSKTRDITGGLP
EECCCCCEEEECCCHHHHHHHHHHCEEEEECCCCEEEECHHHHHCCCCCCCCCCCCCCCH
RVADLFEARTPKDAAILAEVSGTLAFGKETKGKRRLVITQANGEAYEEMVPKWRHLNIFE
HHHHHHHCCCCCCCEEEEECCCCEEECCCCCCCEEEEEEECCCHHHHHHCCCHHCCCCCC
GEKIEKGEVISDGPESPHDILRLRGISPVANYITNEVQEVYRLQGVKINDKHIEVIVNQM
CCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHH
LRKGTITDNGDSAFLVGEQAEVARVVIENRRLVAEGKAIATFDYQLLGITKASLATESFI
HHCCCCCCCCCCEEEECCHHHHHHHHHHCCEEEECCCEEEEEEEEEEECHHHHHHHHHHH
SAASFQETTRVLTEAAVAGKCDQLHGLKENVIVGRLIPAGTGFAHHRARAAAKAAELAPK
HHHHHHHHHHHHHHHHHHCCCHHHCCCHHCEEEEEEECCCCCHHHHHHHHHHHHHHHCCH
VEETIVDTGTAEQNLADLLNAVDFGD
HHHHHHCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKDLLKFLKQQNKTKEFDGIKIGLASPEMVRSWSFGEVKKPETINYRTFKPEREGLFCAR
CHHHHHHHHHCCCCCCCCCEEEECCCHHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTQSKVRRDRMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRIGLMLDMTLRDIERILYFESFVVVEPGMTDLERRQILLEEEYLDMLEQWGDEFEAVM
HHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHH
GAEAIFSLLKQLDLDHEIAEMREELGTTNSETKRKKLTKRLKLVESFHQSSNKPEWMILT
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHH
ESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPT
HHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCC
LRLHQCGLPKKMALELFKPFVYGKLEALGLATTIKAAKKLVDREGGEVWDILEGVIREHP
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
VLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTIEAQLEA
EEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEEEEEEEEEECCCE
RTLMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRSKINSLGEDMWFQSAKEAEKAYRAG
EEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGLQAIVKVRMKQVHIADDKSRTETTNIIETTVGRAILSLIMPEGLPFELVDLPMGKKQ
HHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHH
ISTALNACYRLLGIKHTVIFADQLMYTGFEYATLSGASVCIDDMVIPTTKKTLVEAAEAE
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEECCCCCEECCCEECCCCHHHHHHHHHHH
VQEIHEQFQAGLVTAGERYNKVIDIWASANEQVAKAMMENLSKDTVVNSKGEEVQQDSFN
HHHHHHHHHCCCHHCCHHHCCEEEEECCCCHHHHHHHHHHCCCCCEECCCCCHHHHCCCC
SVYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
KGLADTALKTANSGYLTRRLVDIAQDLVITEKDCGSEDGLLVTPLIQGGDVVEALRERVL
CCHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHH
GRVVAQDIIKPGTKGEVLIARNVLLDEKLCDLIEEASVDQVWVRSVITCQTDFGACAQCY
HHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHH
GRDLARGHMVGQGEAIGVMAAQSIGEPGTQLTMRTFHIGGAASRAASENNIQVKNTGKIK
CCHHHCCCCCCCCCEEEEEEHHHCCCCCCEEEEEEEEECCHHHHCCCCCCEEEEECCEEE
LHNAKFVINSEQKVVVTSRSTELTIIDKLGRTKENHRLPYGAVLEKQDGAEITSGEIIAN
EECEEEEECCCCEEEEEECCCEEEEEHHHCCCCCCCCCCCHHEEECCCCCCCCCCCEEEC
WDPHTHPIITEVEGTVQFLDFIEGLSITKQADEFTGLSSTVIIDPAQRPNAGKELRPMVK
CCCCCCCEEEECHHHHHHHHHHCCCCHHCCHHHHCCCCCEEEECCCCCCCCCHHHHHHHH
LVDPQGNDLFIPGTDVAAQYALAANAIVSLEDGAKVRVGDAVARIPQESSKTRDITGGLP
EECCCCCEEEECCCHHHHHHHHHHCEEEEECCCCEEEECHHHHHCCCCCCCCCCCCCCCH
RVADLFEARTPKDAAILAEVSGTLAFGKETKGKRRLVITQANGEAYEEMVPKWRHLNIFE
HHHHHHHCCCCCCCEEEEECCCCEEECCCCCCCEEEEEEECCCHHHHHHCCCHHCCCCCC
GEKIEKGEVISDGPESPHDILRLRGISPVANYITNEVQEVYRLQGVKINDKHIEVIVNQM
CCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHH
LRKGTITDNGDSAFLVGEQAEVARVVIENRRLVAEGKAIATFDYQLLGITKASLATESFI
HHCCCCCCCCCCEEEECCHHHHHHHHHHCCEEEECCCEEEEEEEEEEECHHHHHHHHHHH
SAASFQETTRVLTEAAVAGKCDQLHGLKENVIVGRLIPAGTGFAHHRARAAAKAAELAPK
HHHHHHHHHHHHHHHHHHCCCHHHCCCHHCEEEEEEECCCCCHHHHHHHHHHHHHHHCCH
VEETIVDTGTAEQNLADLLNAVDFGD
HHHHHHCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA