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The map label for this gene is rpoB

Identifier: 119947049

GI number: 119947049

Start: 4260240

End: 4264280

Strand: Reverse

Name: rpoB

Synonym: Ping_3446

Alternate gene names: 119947049

Gene position: 4264280-4260240 (Counterclockwise)

Preceding gene: 119947050

Following gene: 119947048

Centisome position: 93.52

GC content: 42.32

Gene sequence:

>4041_bases
ATGGGTTACTCTTATACTGAGAAAAAACGTATTCGTAAGGATTTTGGTAAACGTCCACAGGTGATGGAAAAACCATACCT
GTTGTCGATTCAACTAGATTCATTCAAACGATTCATTGAAGTCGATTTAACTGGAGAAGTTGGTCTTGAGGCTGCTTTTA
ACAGCATCTTCCCTATCGCCAGTTATTCCGGTACATCAGAATTGCAATATGTCAGCTACCGTTTAGGTGAGCCGGTATTT
GATGTGAAAGAATGCCAAATCCGTGGAGTAACATACTCTGCTTCATTGCGCGTTAAATTACGTCTTGTTATTTATGATCG
TGATGCACCAGCCGGCACGGTTAAAGATATTCGTGAACAAGAAGTATACATGGGTGAAATGCCACTCATGACAGAAAATG
GTACTTTTGTAATCAATGGTACTGAGCGTGTTATCGTTTCGCAATTACATCGTAGTCCTGGTGTCTTCTTTGACCACGAT
AAAGGTAAAACGCATAGTTCTGGTAAAGTACTTTATAATGCACGCGTAATTCCATACCGCGGTTCTTGGTTAGACTTTGA
ATTTGATCCTAAAGATAACCTCTTTGTTCGTATTGACCGTCGTCGTAAACTCCCTGCAACTATTATGTTGCGAGCGCTTG
AGTATTCGACACAAGAAATTCTGGCCATATTCTACGACACAACTAAATTTGACATCAAAGACGGTGTTATTTCAATGTCG
CTAATTGCTGACCGCTTACGTGGTGAGATGGCGTTATTTGATATTGCAGCAAACGGCAAGATTTATGTTGAGCAGGGCAA
GCGTATTACAGCGCGCCATATTAAACAGCTTGAAAAAGATAATATCAATACGCTTGACGTGCCAGTTGAGTACATTGCAG
AGAAAGATCTGGTTGTTGCTAAAGATTATATCAGCAAAGAAACCGGTGAAATCATTGTTAGTGCCAACGACATATTAACG
CTTGAAATATTAGCGGAACTGACTCAGTCAGGCATTACATCCTTTGATATTATTTATACTAATGAACTGGACTGCGGTTC
GTTTATTTCCGATACATTACGTGTTGATAGTTCAAGTAATCGCCTTGAAGCGTTAGTTGAAATCTACCGCATGATGCGTC
CGGGTGAGCCACCAACAAAAGACGCAGCAGAAGGTTTATTCCATAACCTGTTTTTTGCTGAAGAACGTTACGAGCTTTCT
AAAGTTGGCCGTATGAAGTTCAACCGTCGTGTTGGTATTGATGGTGATGAAGGCGCTGGTATTTTATCCAAGGATGATAT
ATTAAGTGTGATGAAAACACTGATTGCTATCCGTAATGGTGATGGCATTGTCGATGATATCGACCATCTTGGTAACCGCC
GTATCCGTTGTGTTGGTGAAATGGCTGAAAACCAATTCCGTGTTGGTTTAGTCCGTGTTGAGCGTGCCGTAAGAGAACGT
CTTTCTCTGGGCGATCTTGATGCGACTATGCCACAAGATTTAATCAATGCTAAACCTATTTCTGCTGCTGTTAAAGAGTT
CTTTGGTTCATCACAACTGTCACAGTTTATGGATCAAAATAACCCGCTTTCAGAAGTAACCCATAAACGTCGTATTTCAG
CATTAGGGCCTGGTGGTCTAACGCGTGAACGTGCCGGCTTTGAAGTACGTGACGTACATCCAACGCATTACGGTCGTTTG
TGTCCAATCGAAACCCCAGAGGGACCAAACATTGGTCTGATTAACTCTTTGGCAACTTTCTCACGCACCAACAGTTACGG
TTTCTTAGAAACACCTTACCGTAAAGTTGAAAATGGTAAACCAACAGATCAAGTTGAATACCTTTCTGCGATTGAAGAAG
GTTCATTCGTCATTGCACAGGCAAGCGCCAGTATTGATGAAAATGGTTTGCTGGACGAAGAATTGATCCCTTGTCGTCAT
AAAGGTGAGTCTACCTTTTTGAGCCCTGCGGATATCGATTATATGGACGTATCACCACAGCAGATTATTTCTGTTGCGGC
GTCATTGATTCCATTCCTAGAGCATGATGATGCTAACCGTGCCTTAATGGGTTCGAACATGCAACGTCAAGCCGTTCCAA
CACTACGTGCGGACAAACCGCTTGTAGGAACAGGTATTGAACGTCGTCTTGCAATCGATTCTGGTGTAACAATCATCGCT
AAACGTAGTGGTGTTATTGATTATGTCGATGCATCACGTATTGTTGTTAAAGTTGATGATAACGAGCTCCTTCCTGGTGA
AGCGGGTATCGATATTTACAATTTAACTAAATACACCCGTTCAAATCAGAATACCTGTATTAACCAAAAACCTACCTGTG
AACCTGGCGAACCTATTGTTCGTGGTGATGTACTGGCCGATGGCCCGTCAACAGATATGGGCGACCTTGCTTTAGGCCAA
AACATGAAGATTGCCTTCATGCCTTGGAATGGTTACAACTTTGAGGATTCAATCCTTATTTCTGAGCGTGTTTCACAGGA
AGACAGATTCACTACAATTCATATTCAAGAGTTCTCATGTGTTGCACGTGAAACTAAATTGGGTAGTGAAGAAATTTCTG
CCGATATCCCGAACGTTGGCGAAGCGGCACTAAGTAAACTTGATGAATCAGGTATTGTATACGTAGGTGCTGAAGTTAAA
CCTGGCGATATACTTGTTGGTAAAGTGACACCTAAAGGTGAAACACAGCTAACACCTGAAGAAAAACTATTACGAGCTAT
CTTTGGTGAGAAAGCATCAGACGTTAAAGACAGTTCTTTACGCGTGGCAGCCTCAACCTACGCAACGGTTATTGACGTAC
AAGTCTTTACTCGAGATGGTGTTGAAAAAGATAAACGTGCGCTTGAAATAGAAGAAATGCAGCTTAAAGCGGCGAAGAAA
GATTTAACTGAAAAGTTCAAAATCTTAGAAAACGCAATTTATGAAAAAGCCTTAGCGATTCTTGTTGGTGCCGGTCAGGA
TGAAGCGCGTCTGCTACAGATGCCTCGTGCACAGTGGTTAGAAGTGCAGATTGATGATGAAACTAAACAGTCTTATTTAG
ATCAAATCATTACTCAATATGATGAAGTCAAAGCTGATTACGATAAAGAGTTTGATATCAAACGTCGCAAAATCACTCAA
GGTGATGATCTTGCACCTGGTGTTCAGAAGATTGTTAAAGTGTATCTAGCTGTCCGTCGTCGCCTGCAACCTGGTGATAA
AATGGCGGGTCGTCACGGTAACAAAGGTGTTATTTCAAACATCGTGCCCGTAGAAGATATGCCGCATGATGAGTTTGGTG
TTCCTGTTGATATCGTACTTAACCCGCTGGGTGTACCGTCACGGATGAACATCGGTCAGGTTTTGGAAACTCACTTAGGT
CTTGCTGCCAAAGGTGTGGGCGAAAAACTTGAGCGTATGATTAAATACCAGCGTGACATTGAAATTACTAAAGTGCGCGA
ATTCGTTCAGAAACTATACTCTTTCGGTGATGCGCCATGTCATGTTGATCTTAACGATTTTGATGATGAAGCGGTAATGC
GTTTAGCTAAGAACCTGTACAAAGGGTTACCTGTTGCAACACCTGCATTTGATGGTGCCAACGAAGGCGAAATCCGTGAG
CTGTTACGCATGGCTGATTTGCCTGAATCAGGTCAATTACAACTGACCGATGGCCGTACGGGTATTCAGTTTGAACGTCC
TGTGACCGTTGGTTATATGTACATGCTGAAACTGAATCACTTGGTTGATGACAAGATGCATGCGCGTTCTACTGGCTCTT
ACAGCTTAGTAACACAGCAGCCGCTTGGTGGTAAAGCGCAGTTCGGTGGACAACGTTTTGGTGAGATGGAAGTATGGGCA
TTAGAAGCTTATGGTGCTGCTTACACTCTACAAGAAATGCTGACGGTTAAATCCGATGATGTTAACGGTCGTACTAAGAT
GTATAAAAACATCGTTGACGGCGACCATAGAATGGAACCGGGCATGCCTGAATCATTCAACGTATTGTTGAAAGAGATCC
GTTCATTAAGCATCAACATTGAACTAGATGAAAGTAACTAA

Upstream 100 bases:

>100_bases
CATCATTAACACGAAAATAATGTTCGCCGTTGTCTAATAATAGAGGTCTAAAAATAGACCAGGACAGCTATGATCACTTA
TCAGCGAGCAAAGGAACCAC

Downstream 100 bases:

>100_bases
GCATTAAGCTGTAGTAAATATGTGGCGTCTTGAAAATTAAGGCGCCTAGTTTTAACTCCTATGGGAGAGTAGCGTGAAAG
ACTTATTAAAGTTTTTAAAG

Product: DNA-directed RNA polymerase, beta subunit

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1346; Mature: 1345

Protein sequence:

>1346_residues
MGYSYTEKKRIRKDFGKRPQVMEKPYLLSIQLDSFKRFIEVDLTGEVGLEAAFNSIFPIASYSGTSELQYVSYRLGEPVF
DVKECQIRGVTYSASLRVKLRLVIYDRDAPAGTVKDIREQEVYMGEMPLMTENGTFVINGTERVIVSQLHRSPGVFFDHD
KGKTHSSGKVLYNARVIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIMLRALEYSTQEILAIFYDTTKFDIKDGVISMS
LIADRLRGEMALFDIAANGKIYVEQGKRITARHIKQLEKDNINTLDVPVEYIAEKDLVVAKDYISKETGEIIVSANDILT
LEILAELTQSGITSFDIIYTNELDCGSFISDTLRVDSSSNRLEALVEIYRMMRPGEPPTKDAAEGLFHNLFFAEERYELS
KVGRMKFNRRVGIDGDEGAGILSKDDILSVMKTLIAIRNGDGIVDDIDHLGNRRIRCVGEMAENQFRVGLVRVERAVRER
LSLGDLDATMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRL
CPIETPEGPNIGLINSLATFSRTNSYGFLETPYRKVENGKPTDQVEYLSAIEEGSFVIAQASASIDENGLLDEELIPCRH
KGESTFLSPADIDYMDVSPQQIISVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGIERRLAIDSGVTIIA
KRSGVIDYVDASRIVVKVDDNELLPGEAGIDIYNLTKYTRSNQNTCINQKPTCEPGEPIVRGDVLADGPSTDMGDLALGQ
NMKIAFMPWNGYNFEDSILISERVSQEDRFTTIHIQEFSCVARETKLGSEEISADIPNVGEAALSKLDESGIVYVGAEVK
PGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVAASTYATVIDVQVFTRDGVEKDKRALEIEEMQLKAAKK
DLTEKFKILENAIYEKALAILVGAGQDEARLLQMPRAQWLEVQIDDETKQSYLDQIITQYDEVKADYDKEFDIKRRKITQ
GDDLAPGVQKIVKVYLAVRRRLQPGDKMAGRHGNKGVISNIVPVEDMPHDEFGVPVDIVLNPLGVPSRMNIGQVLETHLG
LAAKGVGEKLERMIKYQRDIEITKVREFVQKLYSFGDAPCHVDLNDFDDEAVMRLAKNLYKGLPVATPAFDGANEGEIRE
LLRMADLPESGQLQLTDGRTGIQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWA
LEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLLKEIRSLSINIELDESN

Sequences:

>Translated_1346_residues
MGYSYTEKKRIRKDFGKRPQVMEKPYLLSIQLDSFKRFIEVDLTGEVGLEAAFNSIFPIASYSGTSELQYVSYRLGEPVF
DVKECQIRGVTYSASLRVKLRLVIYDRDAPAGTVKDIREQEVYMGEMPLMTENGTFVINGTERVIVSQLHRSPGVFFDHD
KGKTHSSGKVLYNARVIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIMLRALEYSTQEILAIFYDTTKFDIKDGVISMS
LIADRLRGEMALFDIAANGKIYVEQGKRITARHIKQLEKDNINTLDVPVEYIAEKDLVVAKDYISKETGEIIVSANDILT
LEILAELTQSGITSFDIIYTNELDCGSFISDTLRVDSSSNRLEALVEIYRMMRPGEPPTKDAAEGLFHNLFFAEERYELS
KVGRMKFNRRVGIDGDEGAGILSKDDILSVMKTLIAIRNGDGIVDDIDHLGNRRIRCVGEMAENQFRVGLVRVERAVRER
LSLGDLDATMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRL
CPIETPEGPNIGLINSLATFSRTNSYGFLETPYRKVENGKPTDQVEYLSAIEEGSFVIAQASASIDENGLLDEELIPCRH
KGESTFLSPADIDYMDVSPQQIISVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGIERRLAIDSGVTIIA
KRSGVIDYVDASRIVVKVDDNELLPGEAGIDIYNLTKYTRSNQNTCINQKPTCEPGEPIVRGDVLADGPSTDMGDLALGQ
NMKIAFMPWNGYNFEDSILISERVSQEDRFTTIHIQEFSCVARETKLGSEEISADIPNVGEAALSKLDESGIVYVGAEVK
PGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVAASTYATVIDVQVFTRDGVEKDKRALEIEEMQLKAAKK
DLTEKFKILENAIYEKALAILVGAGQDEARLLQMPRAQWLEVQIDDETKQSYLDQIITQYDEVKADYDKEFDIKRRKITQ
GDDLAPGVQKIVKVYLAVRRRLQPGDKMAGRHGNKGVISNIVPVEDMPHDEFGVPVDIVLNPLGVPSRMNIGQVLETHLG
LAAKGVGEKLERMIKYQRDIEITKVREFVQKLYSFGDAPCHVDLNDFDDEAVMRLAKNLYKGLPVATPAFDGANEGEIRE
LLRMADLPESGQLQLTDGRTGIQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWA
LEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLLKEIRSLSINIELDESN
>Mature_1345_residues
GYSYTEKKRIRKDFGKRPQVMEKPYLLSIQLDSFKRFIEVDLTGEVGLEAAFNSIFPIASYSGTSELQYVSYRLGEPVFD
VKECQIRGVTYSASLRVKLRLVIYDRDAPAGTVKDIREQEVYMGEMPLMTENGTFVINGTERVIVSQLHRSPGVFFDHDK
GKTHSSGKVLYNARVIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIMLRALEYSTQEILAIFYDTTKFDIKDGVISMSL
IADRLRGEMALFDIAANGKIYVEQGKRITARHIKQLEKDNINTLDVPVEYIAEKDLVVAKDYISKETGEIIVSANDILTL
EILAELTQSGITSFDIIYTNELDCGSFISDTLRVDSSSNRLEALVEIYRMMRPGEPPTKDAAEGLFHNLFFAEERYELSK
VGRMKFNRRVGIDGDEGAGILSKDDILSVMKTLIAIRNGDGIVDDIDHLGNRRIRCVGEMAENQFRVGLVRVERAVRERL
SLGDLDATMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLC
PIETPEGPNIGLINSLATFSRTNSYGFLETPYRKVENGKPTDQVEYLSAIEEGSFVIAQASASIDENGLLDEELIPCRHK
GESTFLSPADIDYMDVSPQQIISVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGIERRLAIDSGVTIIAK
RSGVIDYVDASRIVVKVDDNELLPGEAGIDIYNLTKYTRSNQNTCINQKPTCEPGEPIVRGDVLADGPSTDMGDLALGQN
MKIAFMPWNGYNFEDSILISERVSQEDRFTTIHIQEFSCVARETKLGSEEISADIPNVGEAALSKLDESGIVYVGAEVKP
GDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVAASTYATVIDVQVFTRDGVEKDKRALEIEEMQLKAAKKD
LTEKFKILENAIYEKALAILVGAGQDEARLLQMPRAQWLEVQIDDETKQSYLDQIITQYDEVKADYDKEFDIKRRKITQG
DDLAPGVQKIVKVYLAVRRRLQPGDKMAGRHGNKGVISNIVPVEDMPHDEFGVPVDIVLNPLGVPSRMNIGQVLETHLGL
AAKGVGEKLERMIKYQRDIEITKVREFVQKLYSFGDAPCHVDLNDFDDEAVMRLAKNLYKGLPVATPAFDGANEGEIREL
LRMADLPESGQLQLTDGRTGIQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWAL
EAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLLKEIRSLSINIELDESN

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI238908505, Length=298, Percent_Identity=31.2080536912752, Blast_Score=117, Evalue=6e-26,
Organism=Homo sapiens, GI238908503, Length=298, Percent_Identity=31.2080536912752, Blast_Score=117, Evalue=7e-26,
Organism=Homo sapiens, GI4505941, Length=305, Percent_Identity=29.1803278688525, Blast_Score=109, Evalue=2e-23,
Organism=Homo sapiens, GI33469941, Length=82, Percent_Identity=45.1219512195122, Blast_Score=75, Evalue=4e-13,
Organism=Homo sapiens, GI212286172, Length=82, Percent_Identity=45.1219512195122, Blast_Score=75, Evalue=4e-13,
Organism=Escherichia coli, GI1790419, Length=1345, Percent_Identity=76.9516728624535, Blast_Score=2160, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=303, Percent_Identity=29.7029702970297, Blast_Score=117, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17506623, Length=235, Percent_Identity=31.9148936170213, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17552304, Length=250, Percent_Identity=31.2, Blast_Score=106, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6325267, Length=351, Percent_Identity=28.4900284900285, Blast_Score=108, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6324725, Length=250, Percent_Identity=31.6, Blast_Score=107, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6324781, Length=160, Percent_Identity=31.25, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17136446, Length=292, Percent_Identity=30.8219178082192, Blast_Score=108, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17136444, Length=250, Percent_Identity=30.4, Blast_Score=101, Evalue=5e-21,
Organism=Drosophila melanogaster, GI17647877, Length=249, Percent_Identity=28.1124497991968, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_PSYIN (A1T065)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944729.1
- STRING:   A1T065
- GeneID:   4625600
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_3446
- eggNOG:   COG0085
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- PhylomeDB:   A1T065
- BioCyc:   PING357804:PING_3446-MONOMER
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 150450; Mature: 150319

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYSYTEKKRIRKDFGKRPQVMEKPYLLSIQLDSFKRFIEVDLTGEVGLEAAFNSIFPIA
CCCCHHHHHHHHHHHCCCCCHHCCCEEEEEEHHHCCEEEEEEECCCCCHHHHHHCCCCCC
SYSGTSELQYVSYRLGEPVFDVKECQIRGVTYSASLRVKLRLVIYDRDAPAGTVKDIREQ
CCCCCCHHHHHHHHCCCCCCCCCCEEEEEEEEEEEEEEEEEEEEEECCCCCCHHHHHHHH
EVYMGEMPLMTENGTFVINGTERVIVSQLHRSPGVFFDHDKGKTHSSGKVLYNARVIPYR
HHHCCCCCEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEEEEC
GSWLDFEFDPKDNLFVRIDRRRKLPATIMLRALEYSTQEILAIFYDTTKFDIKDGVISMS
CCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHCHHHEEEEEECCCEEECCCCHHHHH
LIADRLRGEMALFDIAANGKIYVEQGKRITARHIKQLEKDNINTLDVPVEYIAEKDLVVA
HHHHHHCCCEEEEEEECCCEEEEECCCEEHHHHHHHHHHCCCCEEECCHHHHCCCCEEEE
KDYISKETGEIIVSANDILTLEILAELTQSGITSFDIIYTNELDCGSFISDTLRVDSSSN
HHHHCCCCCCEEEECCCEEHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHEECCCCH
RLEALVEIYRMMRPGEPPTKDAAEGLFHNLFFAEERYELSKVGRMKFNRRVGIDGDEGAG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
ILSKDDILSVMKTLIAIRNGDGIVDDIDHLGNRRIRCVGEMAENQFRVGLVRVERAVRER
CCCHHHHHHHHHHHHEECCCCCCHHHHHHCCCCEEEEEEHHHCCCHHHHHHHHHHHHHHH
LSLGDLDATMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGL
CCCCCCCCCCCHHHHCCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
TRERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLATFSRTNSYGFLETPYRKVENGK
CHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHCCCC
PTDQVEYLSAIEEGSFVIAQASASIDENGLLDEELIPCRHKGESTFLSPADIDYMDVSPQ
CCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCHH
QIISVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGIERRLAIDSGVTIIA
HHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCEEEEE
KRSGVIDYVDASRIVVKVDDNELLPGEAGIDIYNLTKYTRSNQNTCINQKPTCEPGEPIV
ECCCCEEEECCCEEEEEECCCCCCCCCCCCEEEEHHHHHCCCCCCCCCCCCCCCCCCCEE
RGDVLADGPSTDMGDLALGQNMKIAFMPWNGYNFEDSILISERVSQEDRFTTIHIQEFSC
ECCEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEHHHCCCCCCEEEEEEEHHHH
VARETKLGSEEISADIPNVGEAALSKLDESGIVYVGAEVKPGDILVGKVTPKGETQLTPE
HHHHHCCCCHHHHCCCCCCCHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCHH
EKLLRAIFGEKASDVKDSSLRVAASTYATVIDVQVFTRDGVEKDKRALEIEEMQLKAAKK
HHHHHHHHCCCCCCCCCCCEEEEEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
DLTEKFKILENAIYEKALAILVGAGQDEARLLQMPRAQWLEVQIDDETKQSYLDQIITQY
HHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHH
DEVKADYDKEFDIKRRKITQGDDLAPGVQKIVKVYLAVRRRLQPGDKMAGRHGNKGVISN
HHHHCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCC
IVPVEDMPHDEFGVPVDIVLNPLGVPSRMNIGQVLETHLGLAAKGVGEKLERMIKYQRDI
CCCCCCCCCCCCCCCHHEEECCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCC
EITKVREFVQKLYSFGDAPCHVDLNDFDDEAVMRLAKNLYKGLPVATPAFDGANEGEIRE
HHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
LLRMADLPESGQLQLTDGRTGIQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQ
HHHHHCCCCCCCEEEECCCCCCEECCCCHHHHHEEHHHHHHHCCHHHHCCCCCEEEEECC
PLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEP
CCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC
GMPESFNVLLKEIRSLSINIELDESN
CCCHHHHHHHHHHHCEEEEEEEECCC
>Mature Secondary Structure 
GYSYTEKKRIRKDFGKRPQVMEKPYLLSIQLDSFKRFIEVDLTGEVGLEAAFNSIFPIA
CCCHHHHHHHHHHHCCCCCHHCCCEEEEEEHHHCCEEEEEEECCCCCHHHHHHCCCCCC
SYSGTSELQYVSYRLGEPVFDVKECQIRGVTYSASLRVKLRLVIYDRDAPAGTVKDIREQ
CCCCCCHHHHHHHHCCCCCCCCCCEEEEEEEEEEEEEEEEEEEEEECCCCCCHHHHHHHH
EVYMGEMPLMTENGTFVINGTERVIVSQLHRSPGVFFDHDKGKTHSSGKVLYNARVIPYR
HHHCCCCCEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEEEEC
GSWLDFEFDPKDNLFVRIDRRRKLPATIMLRALEYSTQEILAIFYDTTKFDIKDGVISMS
CCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHCHHHEEEEEECCCEEECCCCHHHHH
LIADRLRGEMALFDIAANGKIYVEQGKRITARHIKQLEKDNINTLDVPVEYIAEKDLVVA
HHHHHHCCCEEEEEEECCCEEEEECCCEEHHHHHHHHHHCCCCEEECCHHHHCCCCEEEE
KDYISKETGEIIVSANDILTLEILAELTQSGITSFDIIYTNELDCGSFISDTLRVDSSSN
HHHHCCCCCCEEEECCCEEHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHEECCCCH
RLEALVEIYRMMRPGEPPTKDAAEGLFHNLFFAEERYELSKVGRMKFNRRVGIDGDEGAG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
ILSKDDILSVMKTLIAIRNGDGIVDDIDHLGNRRIRCVGEMAENQFRVGLVRVERAVRER
CCCHHHHHHHHHHHHEECCCCCCHHHHHHCCCCEEEEEEHHHCCCHHHHHHHHHHHHHHH
LSLGDLDATMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGL
CCCCCCCCCCCHHHHCCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
TRERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLATFSRTNSYGFLETPYRKVENGK
CHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHCCCC
PTDQVEYLSAIEEGSFVIAQASASIDENGLLDEELIPCRHKGESTFLSPADIDYMDVSPQ
CCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCHH
QIISVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGIERRLAIDSGVTIIA
HHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCEEEEE
KRSGVIDYVDASRIVVKVDDNELLPGEAGIDIYNLTKYTRSNQNTCINQKPTCEPGEPIV
ECCCCEEEECCCEEEEEECCCCCCCCCCCCEEEEHHHHHCCCCCCCCCCCCCCCCCCCEE
RGDVLADGPSTDMGDLALGQNMKIAFMPWNGYNFEDSILISERVSQEDRFTTIHIQEFSC
ECCEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEHHHCCCCCCEEEEEEEHHHH
VARETKLGSEEISADIPNVGEAALSKLDESGIVYVGAEVKPGDILVGKVTPKGETQLTPE
HHHHHCCCCHHHHCCCCCCCHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCHH
EKLLRAIFGEKASDVKDSSLRVAASTYATVIDVQVFTRDGVEKDKRALEIEEMQLKAAKK
HHHHHHHHCCCCCCCCCCCEEEEEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
DLTEKFKILENAIYEKALAILVGAGQDEARLLQMPRAQWLEVQIDDETKQSYLDQIITQY
HHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHH
DEVKADYDKEFDIKRRKITQGDDLAPGVQKIVKVYLAVRRRLQPGDKMAGRHGNKGVISN
HHHHCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCC
IVPVEDMPHDEFGVPVDIVLNPLGVPSRMNIGQVLETHLGLAAKGVGEKLERMIKYQRDI
CCCCCCCCCCCCCCCHHEEECCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCC
EITKVREFVQKLYSFGDAPCHVDLNDFDDEAVMRLAKNLYKGLPVATPAFDGANEGEIRE
HHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
LLRMADLPESGQLQLTDGRTGIQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQ
HHHHHCCCCCCCEEEECCCCCCEECCCCHHHHHEEHHHHHHHCCHHHHCCCCCEEEEECC
PLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEP
CCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC
GMPESFNVLLKEIRSLSINIELDESN
CCCHHHHHHHHHHHCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA