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The map label for this gene is gmhB [H]

Identifier: 119946891

GI number: 119946891

Start: 4057106

End: 4057663

Strand: Reverse

Name: gmhB [H]

Synonym: Ping_3285

Alternate gene names: 119946891

Gene position: 4057663-4057106 (Counterclockwise)

Preceding gene: 119946894

Following gene: 119946888

Centisome position: 88.99

GC content: 41.4

Gene sequence:

>558_bases
ATGACAGTAGCCAATGGAAAACGTGCCGTTTTTCTTGATAGAGATGGGGTAATAAATGTCGACAATGGTTATGTATCACA
GCGTGATGATTTTGAATTTATCGACGGCGTCATTGATGCCTGCAAAGCACTTAAAGAAAAAGGCTACCTATTAGTTGTTA
TAACCAATCAGTCCGGTATTGCACGGGGATATTTCAGTGAAGAGCAATTCCATACCTTAACAGAGTGGATGGATTGGTCA
TTAGCAGATAGGGGGGTTGACTTAGATGGTTTCTATTATTGCCCGCATCATGCCGAAAAGGGTATTGGCGAATATAAAAT
TGATTGCGATTGCCGCAAGCCAAAACCTGGCATGCTGATCAGTGCCATTGAAGACCTGGATATAGATGCAAGTCAGTCAA
TATTAGTCGGGGATAAAGTTTCTGATATACAAGCCGGTTTAGCTGCCGGAATAAACACCAACTATTTAGTCCGAACAGGA
AAAACGATCACAGCAGAGGGTGAAAAAATCGCAACAGCCGTATTTGATGATTTGAACAGTATAGTTAAGCTGCTGTAA

Upstream 100 bases:

>100_bases
AATAAAACGTAACATAAGATGCTCTTTATCAATAGAAGGGACTCGCGATGAATGGCATAATAACATTTTTTAATAAACCT
GAAACAGAGAAGGAAATAAT

Downstream 100 bases:

>100_bases
TTGAGTCGTTAAGGGAAAATCTGTGGATAATTATAGTTAATCTGTGGGTAACTTGTTTGCAAATAGGGTATAAAAACTAA
TTGCAAAAATAGGCTGTTTT

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MTVANGKRAVFLDRDGVINVDNGYVSQRDDFEFIDGVIDACKALKEKGYLLVVITNQSGIARGYFSEEQFHTLTEWMDWS
LADRGVDLDGFYYCPHHAEKGIGEYKIDCDCRKPKPGMLISAIEDLDIDASQSILVGDKVSDIQAGLAAGINTNYLVRTG
KTITAEGEKIATAVFDDLNSIVKLL

Sequences:

>Translated_185_residues
MTVANGKRAVFLDRDGVINVDNGYVSQRDDFEFIDGVIDACKALKEKGYLLVVITNQSGIARGYFSEEQFHTLTEWMDWS
LADRGVDLDGFYYCPHHAEKGIGEYKIDCDCRKPKPGMLISAIEDLDIDASQSILVGDKVSDIQAGLAAGINTNYLVRTG
KTITAEGEKIATAVFDDLNSIVKLL
>Mature_184_residues
TVANGKRAVFLDRDGVINVDNGYVSQRDDFEFIDGVIDACKALKEKGYLLVVITNQSGIARGYFSEEQFHTLTEWMDWSL
ADRGVDLDGFYYCPHHAEKGIGEYKIDCDCRKPKPGMLISAIEDLDIDASQSILVGDKVSDIQAGLAAGINTNYLVRTGK
TITAEGEKIATAVFDDLNSIVKLL

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=183, Percent_Identity=59.5628415300546, Blast_Score=232, Evalue=1e-62,
Organism=Escherichia coli, GI87082027, Length=149, Percent_Identity=31.5436241610738, Blast_Score=76, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.1.-

Molecular weight: Translated: 20361; Mature: 20230

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVANGKRAVFLDRDGVINVDNGYVSQRDDFEFIDGVIDACKALKEKGYLLVVITNQSGI
CCCCCCCEEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
ARGYFSEEQFHTLTEWMDWSLADRGVDLDGFYYCPHHAEKGIGEYKIDCDCRKPKPGMLI
CCCCCCCHHHHHHHHHHCCHHHCCCCCCCCEEECCCHHHCCCCCEEEECCCCCCCCCEEE
SAIEDLDIDASQSILVGDKVSDIQAGLAAGINTNYLVRTGKTITAEGEKIATAVFDDLNS
EEHHCCCCCCCCEEEECCCHHHHHHHHHCCCCCCEEEEECCEEEECCCHHHHHHHHHHHH
IVKLL
HHHHC
>Mature Secondary Structure 
TVANGKRAVFLDRDGVINVDNGYVSQRDDFEFIDGVIDACKALKEKGYLLVVITNQSGI
CCCCCCEEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
ARGYFSEEQFHTLTEWMDWSLADRGVDLDGFYYCPHHAEKGIGEYKIDCDCRKPKPGMLI
CCCCCCCHHHHHHHHHHCCHHHCCCCCCCCEEECCCHHHCCCCCEEEECCCCCCCCCEEE
SAIEDLDIDASQSILVGDKVSDIQAGLAAGINTNYLVRTGKTITAEGEKIATAVFDDLNS
EEHHCCCCCCCCEEEECCCHHHHHHHHHCCCCCCEEEEECCEEEECCCHHHHHHHHHHHH
IVKLL
HHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 12101286 [H]