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The map label for this gene is purP [H]

Identifier: 119946419

GI number: 119946419

Start: 3437692

End: 3438987

Strand: Direct

Name: purP [H]

Synonym: Ping_2793

Alternate gene names: 119946419

Gene position: 3437692-3438987 (Clockwise)

Preceding gene: 119946418

Following gene: 119946422

Centisome position: 75.39

GC content: 43.6

Gene sequence:

>1296_bases
ATGTTCGAAAAACTGTTTAAACTCAACGAACACGGAACCTCAGTAAAAACTGAACTTATTGCAGGTACCACCACCTTTTT
AACCATGGCTTATATCATTTTTGTTAACCCGCAAATGTTATCTGCCGCCGGTATGGACTCCGGAGCTGTCTTTGTAGCAA
CTTGTTTAGCAGCTGCACTCGGCTGCTTTATTATGGGATTTTATGCGAACTACCCTGTTGCACTCGCCCCTGGAATGGGT
CTGAATGCCTTTTTCTCTTTTGTGGTTGTTGGCCATATGGGTTACTCATGGCAGGTTGCATTAGGCGCGGTTTTCCTGTC
GGGCATCTGCTTTACACTGCTAAGCCTGTTTAAAATTCGCGAATGGATTATAAACTCAATTCCAATGGCGATGCGTAAAG
GTATTGCAGCGGGTATCGGTTTATTTTTAGCGCTGATTGCACTGAAAAATGCAGGGATTGTTATTTCTAACCCGCCGACA
CTTATCTCACTGGGTGATATGCACGCTTTACCGGCTATTCTTGCTTGTGTGGGTTTCTTTCTCACTATCGCACTGGCACA
TTACCGTGTTAAAGGCGGTGTTATGTTCGCAATTTTAGCGATAACACTGATCGGTTTTTTAGCCGGTGATGTGGAGTATA
ATGGTATTATGTCAATGCCACCAAGTATTGCACCGACACTTCTACAGATGGATATTGCAGGTGCATTCAATGTGGGTATG
ATAAGTATTGTTTTTGCCTTCCTGTTTGTTGATTTGTTTGATACCTCGGGCACCTTAATTGCCGTGGCAGACAAAGGAAA
ACTATTAGATAAAGAAGGAAATTTACCGCGTTTAAATCGTGCCTTATTAGCTGACAGTGGCGCATCAATCGCCGGTTCAA
TGCTGGGTACATCAACCACCACCAGTTATATTGAAAGTATTGCGGGTGTTGCCGAAGGCGGTCGTACCGGGTTAACTGCG
GTGACGGTTGGTCTGTTATTTTTAGTCGCTTTATTCTTTGCTCCATTAGCGGGAATGATACCTGCTTATGCTACAACTGG
CGCATTATTATACGTTGCAGTATTGATGGTGGAAGGGCTGAAAACAATTAACTGGGATGATATTACAGAAGCCGCACCGG
TTGTTGTTGTTACCCTGATGATGCCATTAACCTTTTCTATTGCTAATGGTATTTCGCTTGGTTTTATCGCCTATGCGGCC
ATTAAAGTAATGAGTGGCAAAGCCAAAGACCTAAGTGCAAGCGTTTGGTTCTTAGCGGCATTATTCCTGGCAAAAATGAT
TTTCTTCCCGGGTTAA

Upstream 100 bases:

>100_bases
TGATTTATCCGTTTGTATCTTTTATAATCCCGTCATTTTTATGCATGCCCCCCTGTCTAAAGTCTGTTAGATAGGATCAC
TTATATAATATGGATCTACT

Downstream 100 bases:

>100_bases
AAAGTTTAAATTCACTTTTTAATTGCCAAAAAAAACACCCTTTATTTGCATAAAGGGTGTTTTTTATTTTTCTGCTGTAA
CAATCTTTATAACTCAATAA

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MFEKLFKLNEHGTSVKTELIAGTTTFLTMAYIIFVNPQMLSAAGMDSGAVFVATCLAAALGCFIMGFYANYPVALAPGMG
LNAFFSFVVVGHMGYSWQVALGAVFLSGICFTLLSLFKIREWIINSIPMAMRKGIAAGIGLFLALIALKNAGIVISNPPT
LISLGDMHALPAILACVGFFLTIALAHYRVKGGVMFAILAITLIGFLAGDVEYNGIMSMPPSIAPTLLQMDIAGAFNVGM
ISIVFAFLFVDLFDTSGTLIAVADKGKLLDKEGNLPRLNRALLADSGASIAGSMLGTSTTTSYIESIAGVAEGGRTGLTA
VTVGLLFLVALFFAPLAGMIPAYATTGALLYVAVLMVEGLKTINWDDITEAAPVVVVTLMMPLTFSIANGISLGFIAYAA
IKVMSGKAKDLSASVWFLAALFLAKMIFFPG

Sequences:

>Translated_431_residues
MFEKLFKLNEHGTSVKTELIAGTTTFLTMAYIIFVNPQMLSAAGMDSGAVFVATCLAAALGCFIMGFYANYPVALAPGMG
LNAFFSFVVVGHMGYSWQVALGAVFLSGICFTLLSLFKIREWIINSIPMAMRKGIAAGIGLFLALIALKNAGIVISNPPT
LISLGDMHALPAILACVGFFLTIALAHYRVKGGVMFAILAITLIGFLAGDVEYNGIMSMPPSIAPTLLQMDIAGAFNVGM
ISIVFAFLFVDLFDTSGTLIAVADKGKLLDKEGNLPRLNRALLADSGASIAGSMLGTSTTTSYIESIAGVAEGGRTGLTA
VTVGLLFLVALFFAPLAGMIPAYATTGALLYVAVLMVEGLKTINWDDITEAAPVVVVTLMMPLTFSIANGISLGFIAYAA
IKVMSGKAKDLSASVWFLAALFLAKMIFFPG
>Mature_431_residues
MFEKLFKLNEHGTSVKTELIAGTTTFLTMAYIIFVNPQMLSAAGMDSGAVFVATCLAAALGCFIMGFYANYPVALAPGMG
LNAFFSFVVVGHMGYSWQVALGAVFLSGICFTLLSLFKIREWIINSIPMAMRKGIAAGIGLFLALIALKNAGIVISNPPT
LISLGDMHALPAILACVGFFLTIALAHYRVKGGVMFAILAITLIGFLAGDVEYNGIMSMPPSIAPTLLQMDIAGAFNVGM
ISIVFAFLFVDLFDTSGTLIAVADKGKLLDKEGNLPRLNRALLADSGASIAGSMLGTSTTTSYIESIAGVAEGGRTGLTA
VTVGLLFLVALFFAPLAGMIPAYATTGALLYVAVLMVEGLKTINWDDITEAAPVVVVTLMMPLTFSIANGISLGFIAYAA
IKVMSGKAKDLSASVWFLAALFLAKMIFFPG

Specific function: High-affinity uptake of adenine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=428, Percent_Identity=52.803738317757, Blast_Score=466, Evalue=1e-133,
Organism=Escherichia coli, GI87082309, Length=425, Percent_Identity=51.0588235294118, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI1790499, Length=420, Percent_Identity=40, Blast_Score=285, Evalue=3e-78,
Organism=Escherichia coli, GI48994909, Length=420, Percent_Identity=38.0952380952381, Blast_Score=261, Evalue=5e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45227; Mature: 45227

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEKLFKLNEHGTSVKTELIAGTTTFLTMAYIIFVNPQMLSAAGMDSGAVFVATCLAAAL
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHH
GCFIMGFYANYPVALAPGMGLNAFFSFVVVGHMGYSWQVALGAVFLSGICFTLLSLFKIR
HHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EWIINSIPMAMRKGIAAGIGLFLALIALKNAGIVISNPPTLISLGDMHALPAILACVGFF
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECHHHHHHHHHHHHHHH
LTIALAHYRVKGGVMFAILAITLIGFLAGDVEYNGIMSMPPSIAPTLLQMDIAGAFNVGM
HHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHH
ISIVFAFLFVDLFDTSGTLIAVADKGKLLDKEGNLPRLNRALLADSGASIAGSMLGTSTT
HHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCCCHHHHHHHHCCCCHHHHHHHCCCHH
TSYIESIAGVAEGGRTGLTAVTVGLLFLVALFFAPLAGMIPAYATTGALLYVAVLMVEGL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KTINWDDITEAAPVVVVTLMMPLTFSIANGISLGFIAYAAIKVMSGKAKDLSASVWFLAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LFLAKMIFFPG
HHHHHHHHCCC
>Mature Secondary Structure
MFEKLFKLNEHGTSVKTELIAGTTTFLTMAYIIFVNPQMLSAAGMDSGAVFVATCLAAAL
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHH
GCFIMGFYANYPVALAPGMGLNAFFSFVVVGHMGYSWQVALGAVFLSGICFTLLSLFKIR
HHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EWIINSIPMAMRKGIAAGIGLFLALIALKNAGIVISNPPTLISLGDMHALPAILACVGFF
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECHHHHHHHHHHHHHHH
LTIALAHYRVKGGVMFAILAITLIGFLAGDVEYNGIMSMPPSIAPTLLQMDIAGAFNVGM
HHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHH
ISIVFAFLFVDLFDTSGTLIAVADKGKLLDKEGNLPRLNRALLADSGASIAGSMLGTSTT
HHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCCCHHHHHHHHCCCCHHHHHHHCCCHH
TSYIESIAGVAEGGRTGLTAVTVGLLFLVALFFAPLAGMIPAYATTGALLYVAVLMVEGL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KTINWDDITEAAPVVVVTLMMPLTFSIANGISLGFIAYAAIKVMSGKAKDLSASVWFLAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LFLAKMIFFPG
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]