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The map label for this gene is topA [H]

Identifier: 119945658

GI number: 119945658

Start: 2396646

End: 2399297

Strand: Reverse

Name: topA [H]

Synonym: Ping_1971

Alternate gene names: 119945658

Gene position: 2399297-2396646 (Counterclockwise)

Preceding gene: 229358029

Following gene: 119945657

Centisome position: 52.62

GC content: 43.74

Gene sequence:

>2652_bases
ATGAGCAAATTTCTTGTTATTGTGGAGTCTCCGGCAAAAGCAAAAACGATCAATAAATATCTGGGCAAAGACTTTATTGT
AAAATCAAGCGTAGGTCATATTCGGGATCTTCCAACCAGCGGTAGTGCGAAGAAAAAGATAGAGGCTAAAGGAACTAAGT
CTTTGGCAGGTATGACTCCCGCTAAAAAAGAAAAAGAAAAAGCAAAACGCACACAAAGTGCCTTGGTCGCTAGAATGGGT
GTTGATCCTAATGATCACTGGAAAGCAAATTATGAGATTTTACCGGGCAAAGAAAAAGTAGTTGCAGAATTACAAAAATT
GGCTGTTGATGCCCCCATTATCTATCTCGCAACGGATTTGGATAGAGAGGGAGAAGCGATTGCCTGGCATTTAAGAGAAG
TGCTGGGTGGTGAACACCAGAAATATAAACGTGTTGTTTTTAATGAAATTACTGAAACTGCTATTCAGGAGGCTTTTGAG
CATCCTACCGAATTAAATATTGATGGTGTTAATGCTCAGCAAACCCGCCGTTTTTTAGATCGGGTGGTGGGTTTTATGGT
TTCTCCGTTACTTTGGAAAAAGGTTGCCCGGGGATTATCCGCTGGCAGGGTTCAATCTGTTGCAGTGCGTTTGGTCGTTG
AACGTGAACGTTTAATTAAAGTGTTTAACCCCGTTGAGTTCTGGGATTTACATGCAGATGTGCAGGATAAGACCAAATCT
GATTTGCGTTTAGAAGTCTTTAAAGAAAACGGTAAATTTTTTAAGCCTGTGACTGAAACTGAAACACTTAAAGCGGTCGA
TCATCTTAAATCAGCCGAATATAAAGTACTGTCACGTGAAGATAAACCAACAACCAGTAAGCCAAGTGCTCCTTTTATAA
CTTCGACCCTGCAACAGGCTGCGAGCACCCGTTTAAGCTTTGGTGTTAAAAAGACCATGATGCTGGCGCAACGTCTTTAT
GAAGCCGGTTATATCACCTATATGCGTACCGATTCGACTAACCTGAGTAAAGAGGCAGTGGGGAGTGCGCGAGACTTCAT
CAGTGATGAATTTGGCAAAAATTATTTACCGGCAGAACCGGTCGTTTATAGCAGCAAATCGGGCGCGCAAGAAGCCCATG
AAGCAATACGTCCGTCCGATGTCGGCCAATTAGCGGCCTTACTGGTTGGCGTCGACCGTGATGCGCAACGTTTGTATGAA
CTTATTTGGCGTCAGTTTCTAGCCTGTCAAATGCTCCCTGCTTTGTACGATGCAACCACGCTTGTGGTACAGGCGGGTGA
TTATCAGCTGCGTGCCAAGGGGCGTACACTGCGCTTTGCAGGTTGGACAAAGGTGCAGCCTGTGGCTAAAACTCAGGTGG
ATGAAGTACAGTTCCCAGAGCTCGCCATTGGTGAGGTACTGGAATTAGTCGAGTTGGATCCTAAGCAGCACTTTACTAAA
CCCCCTGCACGTTTTACAGAAGCGGCTTTAGTTAAAGAGCTGGAGAAACAAGGTATTGGCCGTCCATCGACCTATGCCAG
TATTATTTCAACCATTCAGGATCGTGGTTATGTCAAAGTCGATAAGCGGCGTTTTTATGCGGTTAAAATGGGGGAGATTG
TAAGCGATCGTCTTAGTGAAAATTTTGTTGAGTTAATGAGTTATGATTTTACCGCGCAAATGGAACGTAATCTTGATGCC
ATTGCAGAAGGGAAAGCTAATTGGACTGAACAATTAGATGATTTCTATCAGGATCTCACCACACTGTTAGAGAAAGCCGA
ACGAGATCCTGAAGAAGGCGGTATGCGCCTTAATGAACCGGTTATCATTAAGGAGATACATTGTCCTACTTGTGATCGTG
AAATGGGCATCAGAACAGCTTCAACGGGGGTCTTTTTAGGCTGTTCTGGATATGCTCTGCCGCCTAAAGAACGCTGTAAA
ACAACCATCAATTTAGTGGATGGTGAAGAGGTTGTTGATCTTCTATCAAGCGAAGATTTAGAGACCGCTGCGTTAATGGC
TAAACAACGTTGCCCTAAATGCGATATGGCCATGGACAGTTATCTGGTTGATGAGAAAAGAAAACTGCATGTTTGTGGTA
ATAACCCGCTGTGCGATGGTCATCTTGTTGAATATGGTGAATTCAAAATCAAAGGTTATGACGGTCCCGTTGTTGAATGT
GACAAGTGTGGCAGTGATATGCAGTTAAAAGATGGCCGTTTTGGAAAATATATGGGCTGCACTAATGAAGAGTGTAAAAA
TACCCGTAAAATTTTACGCAGTGGCGAAGTTGCGCCGCCTAAAGAAGATCCTGTTGATCTGCCGGAATTAGAGTGTGAGC
AAAGTGATGCGCATTTCATTCTCAGAGATGGTGCCTCGGGTATTTTCTTAGCGGCAAATACGTTTCCTCGTTCTCGAGAA
ACGCGTGCGCCTAAGGTCGCTGAACTGGCGCGTTTTAAAGATCGTATTTCGCCAAAATTTTATTATTTGGCCGAAGCACC
GCAAAAAGACCCAGAGGGTAATTTAGCGGTTGTTCGTTACAGTCGGAAAAACAAAGAACAGTATGTGATGACTGAGATTG
ACAAGAAAGCGACTGGCTGGACCGCAAAGTACATTGATGGTAAATGGGTTGAAGAACAGACTAAAAAACGGGCTGTTAAA
GCGAAGAAATAA

Upstream 100 bases:

>100_bases
ATTCGATTAAAGTTTGGCTTATATAAAAAGGGAATTCATTAGAAGAATGTAAATTTAAGTTTCTTTTCCGCGATTATGAC
TATTTAGGTATGTAAGTATT

Downstream 100 bases:

>100_bases
AGGCATTTTTCGTTGGTAGCGATTAGCTAACATAGTGAATGATATTTACATTGACACTCAGGCGCTTTATCTTGTATTGA
GAGCAGTTCTTGGTAAAGCT

Product: DNA topoisomerase I

Products: NA

Alternate protein names: DNA topoisomerase I; Omega-protein; Relaxing enzyme; Swivelase; Untwisting enzyme [H]

Number of amino acids: Translated: 883; Mature: 882

Protein sequence:

>883_residues
MSKFLVIVESPAKAKTINKYLGKDFIVKSSVGHIRDLPTSGSAKKKIEAKGTKSLAGMTPAKKEKEKAKRTQSALVARMG
VDPNDHWKANYEILPGKEKVVAELQKLAVDAPIIYLATDLDREGEAIAWHLREVLGGEHQKYKRVVFNEITETAIQEAFE
HPTELNIDGVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVERERLIKVFNPVEFWDLHADVQDKTKS
DLRLEVFKENGKFFKPVTETETLKAVDHLKSAEYKVLSREDKPTTSKPSAPFITSTLQQAASTRLSFGVKKTMMLAQRLY
EAGYITYMRTDSTNLSKEAVGSARDFISDEFGKNYLPAEPVVYSSKSGAQEAHEAIRPSDVGQLAALLVGVDRDAQRLYE
LIWRQFLACQMLPALYDATTLVVQAGDYQLRAKGRTLRFAGWTKVQPVAKTQVDEVQFPELAIGEVLELVELDPKQHFTK
PPARFTEAALVKELEKQGIGRPSTYASIISTIQDRGYVKVDKRRFYAVKMGEIVSDRLSENFVELMSYDFTAQMERNLDA
IAEGKANWTEQLDDFYQDLTTLLEKAERDPEEGGMRLNEPVIIKEIHCPTCDREMGIRTASTGVFLGCSGYALPPKERCK
TTINLVDGEEVVDLLSSEDLETAALMAKQRCPKCDMAMDSYLVDEKRKLHVCGNNPLCDGHLVEYGEFKIKGYDGPVVEC
DKCGSDMQLKDGRFGKYMGCTNEECKNTRKILRSGEVAPPKEDPVDLPELECEQSDAHFILRDGASGIFLAANTFPRSRE
TRAPKVAELARFKDRISPKFYYLAEAPQKDPEGNLAVVRYSRKNKEQYVMTEIDKKATGWTAKYIDGKWVEEQTKKRAVK
AKK

Sequences:

>Translated_883_residues
MSKFLVIVESPAKAKTINKYLGKDFIVKSSVGHIRDLPTSGSAKKKIEAKGTKSLAGMTPAKKEKEKAKRTQSALVARMG
VDPNDHWKANYEILPGKEKVVAELQKLAVDAPIIYLATDLDREGEAIAWHLREVLGGEHQKYKRVVFNEITETAIQEAFE
HPTELNIDGVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVERERLIKVFNPVEFWDLHADVQDKTKS
DLRLEVFKENGKFFKPVTETETLKAVDHLKSAEYKVLSREDKPTTSKPSAPFITSTLQQAASTRLSFGVKKTMMLAQRLY
EAGYITYMRTDSTNLSKEAVGSARDFISDEFGKNYLPAEPVVYSSKSGAQEAHEAIRPSDVGQLAALLVGVDRDAQRLYE
LIWRQFLACQMLPALYDATTLVVQAGDYQLRAKGRTLRFAGWTKVQPVAKTQVDEVQFPELAIGEVLELVELDPKQHFTK
PPARFTEAALVKELEKQGIGRPSTYASIISTIQDRGYVKVDKRRFYAVKMGEIVSDRLSENFVELMSYDFTAQMERNLDA
IAEGKANWTEQLDDFYQDLTTLLEKAERDPEEGGMRLNEPVIIKEIHCPTCDREMGIRTASTGVFLGCSGYALPPKERCK
TTINLVDGEEVVDLLSSEDLETAALMAKQRCPKCDMAMDSYLVDEKRKLHVCGNNPLCDGHLVEYGEFKIKGYDGPVVEC
DKCGSDMQLKDGRFGKYMGCTNEECKNTRKILRSGEVAPPKEDPVDLPELECEQSDAHFILRDGASGIFLAANTFPRSRE
TRAPKVAELARFKDRISPKFYYLAEAPQKDPEGNLAVVRYSRKNKEQYVMTEIDKKATGWTAKYIDGKWVEEQTKKRAVK
AKK
>Mature_882_residues
SKFLVIVESPAKAKTINKYLGKDFIVKSSVGHIRDLPTSGSAKKKIEAKGTKSLAGMTPAKKEKEKAKRTQSALVARMGV
DPNDHWKANYEILPGKEKVVAELQKLAVDAPIIYLATDLDREGEAIAWHLREVLGGEHQKYKRVVFNEITETAIQEAFEH
PTELNIDGVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVERERLIKVFNPVEFWDLHADVQDKTKSD
LRLEVFKENGKFFKPVTETETLKAVDHLKSAEYKVLSREDKPTTSKPSAPFITSTLQQAASTRLSFGVKKTMMLAQRLYE
AGYITYMRTDSTNLSKEAVGSARDFISDEFGKNYLPAEPVVYSSKSGAQEAHEAIRPSDVGQLAALLVGVDRDAQRLYEL
IWRQFLACQMLPALYDATTLVVQAGDYQLRAKGRTLRFAGWTKVQPVAKTQVDEVQFPELAIGEVLELVELDPKQHFTKP
PARFTEAALVKELEKQGIGRPSTYASIISTIQDRGYVKVDKRRFYAVKMGEIVSDRLSENFVELMSYDFTAQMERNLDAI
AEGKANWTEQLDDFYQDLTTLLEKAERDPEEGGMRLNEPVIIKEIHCPTCDREMGIRTASTGVFLGCSGYALPPKERCKT
TINLVDGEEVVDLLSSEDLETAALMAKQRCPKCDMAMDSYLVDEKRKLHVCGNNPLCDGHLVEYGEFKIKGYDGPVVECD
KCGSDMQLKDGRFGKYMGCTNEECKNTRKILRSGEVAPPKEDPVDLPELECEQSDAHFILRDGASGIFLAANTFPRSRET
RAPKVAELARFKDRISPKFYYLAEAPQKDPEGNLAVVRYSRKNKEQYVMTEIDKKATGWTAKYIDGKWVEEQTKKRAVKA
KK

Specific function: The reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another [H]

COG id: COG0550

COG function: function code L; Topoisomerase IA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Toprim domain [H]

Homologues:

Organism=Homo sapiens, GI4507635, Length=504, Percent_Identity=28.1746031746032, Blast_Score=137, Evalue=4e-32,
Organism=Homo sapiens, GI10835218, Length=570, Percent_Identity=25.6140350877193, Blast_Score=129, Evalue=1e-29,
Organism=Escherichia coli, GI1787529, Length=871, Percent_Identity=69.6900114810563, Blast_Score=1257, Evalue=0.0,
Organism=Escherichia coli, GI1788061, Length=555, Percent_Identity=23.4234234234234, Blast_Score=97, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI32563869, Length=591, Percent_Identity=24.8730964467005, Blast_Score=132, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17555378, Length=518, Percent_Identity=24.7104247104247, Blast_Score=113, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6323263, Length=539, Percent_Identity=25.0463821892393, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24640096, Length=489, Percent_Identity=28.0163599182004, Blast_Score=123, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24585251, Length=568, Percent_Identity=25.5281690140845, Blast_Score=121, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003601
- InterPro:   IPR013497
- InterPro:   IPR013824
- InterPro:   IPR013825
- InterPro:   IPR000380
- InterPro:   IPR003602
- InterPro:   IPR013498
- InterPro:   IPR005733
- InterPro:   IPR013263
- InterPro:   IPR006171 [H]

Pfam domain/function: PF08272 Topo_Zn_Ribbon; PF01131 Topoisom_bac; PF01751 Toprim; PF01396 zf-C4_Topoisom [H]

EC number: =5.99.1.2 [H]

Molecular weight: Translated: 99331; Mature: 99200

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS00396 TOPOISOMERASE_I_PROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFLVIVESPAKAKTINKYLGKDFIVKSSVGHIRDLPTSGSAKKKIEAKGTKSLAGMTP
CCCEEEEEECCCHHHHHHHHHCCCCEEECCCCHHHCCCCCCCCHHHHHCCCCHHHCCCCC
AKKEKEKAKRTQSALVARMGVDPNDHWKANYEILPGKEKVVAELQKLAVDAPIIYLATDL
CHHHHHHHHHHHHHHHHHHCCCCCCCCEECEEECCCHHHHHHHHHHHHCCCCEEEEEECC
DREGEAIAWHLREVLGGEHQKYKRVVFNEITETAIQEAFEHPTELNIDGVNAQQTRRFLD
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
RVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVERERLIKVFNPVEFWDLHADVQDKTKS
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHCCCC
DLRLEVFKENGKFFKPVTETETLKAVDHLKSAEYKVLSREDKPTTSKPSAPFITSTLQQA
CCEEEEEECCCCEECCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCHHHHHHHHH
ASTRLSFGVKKTMMLAQRLYEAGYITYMRTDSTNLSKEAVGSARDFISDEFGKNYLPAEP
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
VVYSSKSGAQEAHEAIRPSDVGQLAALLVGVDRDAQRLYELIWRQFLACQMLPALYDATT
EEECCCCCHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEE
LVVQAGDYQLRAKGRTLRFAGWTKVQPVAKTQVDEVQFPELAIGEVLELVELDPKQHFTK
EEEECCCEEEEECCCEEEECCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHCCC
PPARFTEAALVKELEKQGIGRPSTYASIISTIQDRGYVKVDKRRFYAVKMGEIVSDRLSE
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEECCEEEEEHHHHHHHHHHHH
NFVELMSYDFTAQMERNLDAIAEGKANWTEQLDDFYQDLTTLLEKAERDPEEGGMRLNEP
HHHHHHHCCHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCC
VIIKEIHCPTCDREMGIRTASTGVFLGCSGYALPPKERCKTTINLVDGEEVVDLLSSEDL
EEEEEECCCCCCHHHCCEEECCCEEEECCCCCCCCHHHHHHEEEECCHHHHHHHHCCCCH
ETAALMAKQRCPKCDMAMDSYLVDEKRKLHVCGNNPLCDGHLVEYGEFKIKGYDGPVVEC
HHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEEECCCEEEECCCCCEEEC
DKCGSDMQLKDGRFGKYMGCTNEECKNTRKILRSGEVAPPKEDPVDLPELECEQSDAHFI
CCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEE
LRDGASGIFLAANTFPRSRETRAPKVAELARFKDRISPKFYYLAEAPQKDPEGNLAVVRY
EECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEE
SRKNKEQYVMTEIDKKATGWTAKYIDGKWVEEQTKKRAVKAKK
CCCCCCHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKFLVIVESPAKAKTINKYLGKDFIVKSSVGHIRDLPTSGSAKKKIEAKGTKSLAGMTP
CCEEEEEECCCHHHHHHHHHCCCCEEECCCCHHHCCCCCCCCHHHHHCCCCHHHCCCCC
AKKEKEKAKRTQSALVARMGVDPNDHWKANYEILPGKEKVVAELQKLAVDAPIIYLATDL
CHHHHHHHHHHHHHHHHHHCCCCCCCCEECEEECCCHHHHHHHHHHHHCCCCEEEEEECC
DREGEAIAWHLREVLGGEHQKYKRVVFNEITETAIQEAFEHPTELNIDGVNAQQTRRFLD
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
RVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVERERLIKVFNPVEFWDLHADVQDKTKS
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHCCCC
DLRLEVFKENGKFFKPVTETETLKAVDHLKSAEYKVLSREDKPTTSKPSAPFITSTLQQA
CCEEEEEECCCCEECCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCHHHHHHHHH
ASTRLSFGVKKTMMLAQRLYEAGYITYMRTDSTNLSKEAVGSARDFISDEFGKNYLPAEP
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
VVYSSKSGAQEAHEAIRPSDVGQLAALLVGVDRDAQRLYELIWRQFLACQMLPALYDATT
EEECCCCCHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEE
LVVQAGDYQLRAKGRTLRFAGWTKVQPVAKTQVDEVQFPELAIGEVLELVELDPKQHFTK
EEEECCCEEEEECCCEEEECCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHCCC
PPARFTEAALVKELEKQGIGRPSTYASIISTIQDRGYVKVDKRRFYAVKMGEIVSDRLSE
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEECCEEEEEHHHHHHHHHHHH
NFVELMSYDFTAQMERNLDAIAEGKANWTEQLDDFYQDLTTLLEKAERDPEEGGMRLNEP
HHHHHHHCCHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCC
VIIKEIHCPTCDREMGIRTASTGVFLGCSGYALPPKERCKTTINLVDGEEVVDLLSSEDL
EEEEEECCCCCCHHHCCEEECCCEEEECCCCCCCCHHHHHHEEEECCHHHHHHHHCCCCH
ETAALMAKQRCPKCDMAMDSYLVDEKRKLHVCGNNPLCDGHLVEYGEFKIKGYDGPVVEC
HHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEEECCCEEEECCCCCEEEC
DKCGSDMQLKDGRFGKYMGCTNEECKNTRKILRSGEVAPPKEDPVDLPELECEQSDAHFI
CCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEE
LRDGASGIFLAANTFPRSRETRAPKVAELARFKDRISPKFYYLAEAPQKDPEGNLAVVRY
EECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEE
SRKNKEQYVMTEIDKKATGWTAKYIDGKWVEEQTKKRAVKAKK
CCCCCCHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3029379; 9097039; 9278503; 3032952; 8114910; 7779808 [H]