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The map label for this gene is fabF [H]

Identifier: 119944849

GI number: 119944849

Start: 1361191

End: 1362432

Strand: Direct

Name: fabF [H]

Synonym: Ping_1091

Alternate gene names: 119944849

Gene position: 1361191-1362432 (Clockwise)

Preceding gene: 119944848

Following gene: 119944850

Centisome position: 29.85

GC content: 43.16

Gene sequence:

>1242_bases
ATGTCAAAAAGAAGAGTCGTTATCACAGGCTTAGGAATGATCACACCCGTAGGCAACACGGTCGATAAGTCATGGGAAGC
GGTTAAATCAGGGAAAAGTGGTATCTCAAATATTGATTTTTTTGATACAACACTGTTTTCTACGAAATTTGCCGGTTTGA
TTAAAGACTTCAATGTCGAAGAATATATGCCGCGTAAAGAAGCCCGAAAAATGGATCTCTTTATTCAGTATGGCATTGCT
GCTGCCGAGCAGGCATTTCAAGATGCTGGGATTGTTGTAACCGCAGAAAATGAAGATCGCATTGGCGTTGCTATTGGCTC
CGGCATTGGCGGCTTGGGGTTAATTGAGAAAAACAAAGAGAGTTTTGATAAAAGTGGCCCTCGTAAGATAAGTCCATTTT
TTGTCCCTTCAACCATCATTAATATGATCTCTGGACATGTATCAATCAATAAAGGCCTAAAAGGTCCCAATATTGCGGTA
ACCACTGCGTGTACAACCGGAACGCACAGTATCGGTCTTGGTGCACGTATGATTCAATATGGTGATGCTGACATAATGAT
CGTTGGCGGGGCGGAAAAAGCATCAACAGAACTTGGCATGGGCGGTTTTGGTGCTGCACGCGCTTTATCGACACGTAATG
ATTCTCCTGAAACAGCAAGCCGTCCTTGGGATAAAGATCGTGATGGTTTTGTACTGGGTGATGGTGCAGGCATATTAGTT
TTAGAAGAATATGAACATGCAAAAGCGCGGGGTGCAAAAATTTATGCTGAATTCGTTGGTTTTGGTATGAGCGGTGATGC
CTACCACATGACTTCACCTCCAGCTGATGGCGCAGGTGCTGCCGCAGCAATGAGAAATGCTATTAAAGATGCTAAAATTA
ACGCTACAGACATTCAATATATTAATGCCCATGGTACATCTACACCTACAGGTGATCTGGCTGAAAATCAAGCAGTAAAA
ACTGTTTGGGGTGATGCAGTTAACGATGTGATGATGAGTTCGACAAAATCGATGACCGGGCATTTGTTGGGTGCCGCGGG
TGCAATTGAGGCTATCTTTAGTGTACTGGCTTTAAAATATCAGCTTGCTCCACCCACGATCAACTTGGAAAATCCAAGTG
AAGGTTGTGATTTAGATTATGTTACTGATGGCAAAGCCCGTCCTGCTGATATTGAATATGCTTTGTCAAACTCATTTGGT
TTTGGCGGGACAAACGCTTCGTTGATCTTTAAACGTATCTAG

Upstream 100 bases:

>100_bases
GTGTTTAAACAGATAATTATACTAACTAAATTAACACTTAAATTTTATCATTAGATGAGTATTTATTTAGTCTAATTTAT
ACATATTAGGAGAAGTTATA

Downstream 100 bases:

>100_bases
TATTGTCAAATCAAGTTAAAATAATAACCCGATTCTAACATCGGGTTTTTTATAGCTAATAGAACTGAATTTATGTTAAT
AAACGGCACTGAATCTACAA

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSKRRVVITGLGMITPVGNTVDKSWEAVKSGKSGISNIDFFDTTLFSTKFAGLIKDFNVEEYMPRKEARKMDLFIQYGIA
AAEQAFQDAGIVVTAENEDRIGVAIGSGIGGLGLIEKNKESFDKSGPRKISPFFVPSTIINMISGHVSINKGLKGPNIAV
TTACTTGTHSIGLGARMIQYGDADIMIVGGAEKASTELGMGGFGAARALSTRNDSPETASRPWDKDRDGFVLGDGAGILV
LEEYEHAKARGAKIYAEFVGFGMSGDAYHMTSPPADGAGAAAAMRNAIKDAKINATDIQYINAHGTSTPTGDLAENQAVK
TVWGDAVNDVMMSSTKSMTGHLLGAAGAIEAIFSVLALKYQLAPPTINLENPSEGCDLDYVTDGKARPADIEYALSNSFG
FGGTNASLIFKRI

Sequences:

>Translated_413_residues
MSKRRVVITGLGMITPVGNTVDKSWEAVKSGKSGISNIDFFDTTLFSTKFAGLIKDFNVEEYMPRKEARKMDLFIQYGIA
AAEQAFQDAGIVVTAENEDRIGVAIGSGIGGLGLIEKNKESFDKSGPRKISPFFVPSTIINMISGHVSINKGLKGPNIAV
TTACTTGTHSIGLGARMIQYGDADIMIVGGAEKASTELGMGGFGAARALSTRNDSPETASRPWDKDRDGFVLGDGAGILV
LEEYEHAKARGAKIYAEFVGFGMSGDAYHMTSPPADGAGAAAAMRNAIKDAKINATDIQYINAHGTSTPTGDLAENQAVK
TVWGDAVNDVMMSSTKSMTGHLLGAAGAIEAIFSVLALKYQLAPPTINLENPSEGCDLDYVTDGKARPADIEYALSNSFG
FGGTNASLIFKRI
>Mature_412_residues
SKRRVVITGLGMITPVGNTVDKSWEAVKSGKSGISNIDFFDTTLFSTKFAGLIKDFNVEEYMPRKEARKMDLFIQYGIAA
AEQAFQDAGIVVTAENEDRIGVAIGSGIGGLGLIEKNKESFDKSGPRKISPFFVPSTIINMISGHVSINKGLKGPNIAVT
TACTTGTHSIGLGARMIQYGDADIMIVGGAEKASTELGMGGFGAARALSTRNDSPETASRPWDKDRDGFVLGDGAGILVL
EEYEHAKARGAKIYAEFVGFGMSGDAYHMTSPPADGAGAAAAMRNAIKDAKINATDIQYINAHGTSTPTGDLAENQAVKT
VWGDAVNDVMMSSTKSMTGHLLGAAGAIEAIFSVLALKYQLAPPTINLENPSEGCDLDYVTDGKARPADIEYALSNSFGF
GGTNASLIFKRI

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=416, Percent_Identity=45.9134615384615, Blast_Score=350, Evalue=2e-96,
Organism=Homo sapiens, GI223972627, Length=166, Percent_Identity=48.7951807228916, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI41872631, Length=426, Percent_Identity=23.4741784037559, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI1787337, Length=413, Percent_Identity=69.9757869249395, Blast_Score=561, Evalue=1e-161,
Organism=Escherichia coli, GI1788663, Length=416, Percent_Identity=38.2211538461538, Blast_Score=250, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71983541, Length=414, Percent_Identity=37.6811594202899, Blast_Score=263, Evalue=9e-71,
Organism=Caenorhabditis elegans, GI71983535, Length=266, Percent_Identity=42.1052631578947, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI212642053, Length=356, Percent_Identity=26.4044943820225, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=413, Percent_Identity=24.455205811138, Blast_Score=102, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6320904, Length=442, Percent_Identity=38.6877828054299, Blast_Score=288, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24644341, Length=423, Percent_Identity=43.9716312056738, Blast_Score=342, Evalue=2e-94,
Organism=Drosophila melanogaster, GI19920632, Length=376, Percent_Identity=23.6702127659574, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI221330659, Length=376, Percent_Identity=23.6702127659574, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24581345, Length=422, Percent_Identity=22.5118483412322, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43547; Mature: 43416

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRRVVITGLGMITPVGNTVDKSWEAVKSGKSGISNIDFFDTTLFSTKFAGLIKDFNVE
CCCCEEEEEECCEECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHH
EYMPRKEARKMDLFIQYGIAAAEQAFQDAGIVVTAENEDRIGVAIGSGIGGLGLIEKNKE
HHCCHHHHHHEEEEEECCHHHHHHHHHHCCEEEEECCCCEEEEEECCCCCCCCEEECCHH
SFDKSGPRKISPFFVPSTIINMISGHVSINKGLKGPNIAVTTACTTGTHSIGLGARMIQY
HHCCCCCCCCCCEECHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEEE
GDADIMIVGGAEKASTELGMGGFGAARALSTRNDSPETASRPWDKDRDGFVLGDGAGILV
CCCCEEEEECCCCCCHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCEEE
LEEYEHAKARGAKIYAEFVGFGMSGDAYHMTSPPADGAGAAAAMRNAIKDAKINATDIQY
EECCCHHHHCCCEEEEHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEE
INAHGTSTPTGDLAENQAVKTVWGDAVNDVMMSSTKSMTGHLLGAAGAIEAIFSVLALKY
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEE
QLAPPTINLENPSEGCDLDYVTDGKARPADIEYALSNSFGFGGTNASLIFKRI
EECCCEEECCCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCCCEEEEEEC
>Mature Secondary Structure 
SKRRVVITGLGMITPVGNTVDKSWEAVKSGKSGISNIDFFDTTLFSTKFAGLIKDFNVE
CCCEEEEEECCEECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHH
EYMPRKEARKMDLFIQYGIAAAEQAFQDAGIVVTAENEDRIGVAIGSGIGGLGLIEKNKE
HHCCHHHHHHEEEEEECCHHHHHHHHHHCCEEEEECCCCEEEEEECCCCCCCCEEECCHH
SFDKSGPRKISPFFVPSTIINMISGHVSINKGLKGPNIAVTTACTTGTHSIGLGARMIQY
HHCCCCCCCCCCEECHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEEE
GDADIMIVGGAEKASTELGMGGFGAARALSTRNDSPETASRPWDKDRDGFVLGDGAGILV
CCCCEEEEECCCCCCHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCEEE
LEEYEHAKARGAKIYAEFVGFGMSGDAYHMTSPPADGAGAAAAMRNAIKDAKINATDIQY
EECCCHHHHCCCEEEEHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEE
INAHGTSTPTGDLAENQAVKTVWGDAVNDVMMSSTKSMTGHLLGAAGAIEAIFSVLALKY
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEE
QLAPPTINLENPSEGCDLDYVTDGKARPADIEYALSNSFGFGGTNASLIFKRI
EECCCEEECCCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]