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The map label for this gene is pabC [H]

Identifier: 119944850

GI number: 119944850

Start: 1362505

End: 1363341

Strand: Direct

Name: pabC [H]

Synonym: Ping_1092

Alternate gene names: 119944850

Gene position: 1362505-1363341 (Clockwise)

Preceding gene: 119944849

Following gene: 119944851

Centisome position: 29.88

GC content: 39.9

Gene sequence:

>837_bases
ATGTTAATAAACGGCACTGAATCTACAACAATTGCAGCCGATGACCGGGGTTTAGCCTACGGAGATGGTCTATTTTCAAC
CATAAAAGTTGAACGTGGTATTGTGCAACTGTGGGATTATCACCTGCAAAGGTTGCAATTGGGTGCAAAAAAGCTTTTTT
TCCCTGAAGTTGATTGGTTATTATTATCAAGCGAACTGCACTATTTAGCAAAGACGGTTGCTGAGCAGCCTTTTGCTGTG
ATTAAAGTAATGCTAACACGAGGCTCCGGGGGACGGGGGTATAGTATTCAAGGATGCAGTTCACCACAACGTATCTTATC
TGTCCATCCTTACCCGGTCTTTTATCAACAATGGCAAAGGGATGGATTAAAGGTAATCCAATGCAGGCAGAAATTAGCGA
TTAATAGACAATTAGCGGGTTTAAAAACATTAAATCGTTTAGAGCAAATATTGATAAAACATGAATTAGAAGCGCAAGAT
GCCTTTGAGGGGATCGTTTGTGATAATGATGGCCACGTTATTGAAGCTTGCAGTGCTAATCTTTTTCTTAAACTAAAAAA
TCACTGGGTGACACCAAAACTTGATGGCTCTGGTATTGCAGGTGTTAAACGTCGACAAATTATGGAATTATCAGCCAAAG
CGGGGCAGCCCATTAGGGAAATGAAGATAACCATTAATGATCTATTAAATGCCCAAGCTGTCTGCTTAAGCAACGCATTA
ATGGGAATAGTACCTGTTATTCAATACCAATCCCATTGTTACCCTGAATCCAGTCTTTTGCATATACAAAAATTACAGTC
ACTAGTAGAGAAAGGAGAGGTGTTTAATGCCGACTAA

Upstream 100 bases:

>100_bases
CGCTTCGTTGATCTTTAAACGTATCTAGTATTGTCAAATCAAGTTAAAATAATAACCCGATTCTAACATCGGGTTTTTTA
TAGCTAATAGAACTGAATTT

Downstream 100 bases:

>100_bases
AAAGATTGTCTTGAGCCTGTTTTTTTTGATATTCCTGGTCTTAGGCAGCGTTATTTGGGGTCAGAAAAAATTAAACAGTT
ATTTAAATACGCCTCTGGTG

Product: aminotransferase, class IV

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MLINGTESTTIAADDRGLAYGDGLFSTIKVERGIVQLWDYHLQRLQLGAKKLFFPEVDWLLLSSELHYLAKTVAEQPFAV
IKVMLTRGSGGRGYSIQGCSSPQRILSVHPYPVFYQQWQRDGLKVIQCRQKLAINRQLAGLKTLNRLEQILIKHELEAQD
AFEGIVCDNDGHVIEACSANLFLKLKNHWVTPKLDGSGIAGVKRRQIMELSAKAGQPIREMKITINDLLNAQAVCLSNAL
MGIVPVIQYQSHCYPESSLLHIQKLQSLVEKGEVFNAD

Sequences:

>Translated_278_residues
MLINGTESTTIAADDRGLAYGDGLFSTIKVERGIVQLWDYHLQRLQLGAKKLFFPEVDWLLLSSELHYLAKTVAEQPFAV
IKVMLTRGSGGRGYSIQGCSSPQRILSVHPYPVFYQQWQRDGLKVIQCRQKLAINRQLAGLKTLNRLEQILIKHELEAQD
AFEGIVCDNDGHVIEACSANLFLKLKNHWVTPKLDGSGIAGVKRRQIMELSAKAGQPIREMKITINDLLNAQAVCLSNAL
MGIVPVIQYQSHCYPESSLLHIQKLQSLVEKGEVFNAD
>Mature_278_residues
MLINGTESTTIAADDRGLAYGDGLFSTIKVERGIVQLWDYHLQRLQLGAKKLFFPEVDWLLLSSELHYLAKTVAEQPFAV
IKVMLTRGSGGRGYSIQGCSSPQRILSVHPYPVFYQQWQRDGLKVIQCRQKLAINRQLAGLKTLNRLEQILIKHELEAQD
AFEGIVCDNDGHVIEACSANLFLKLKNHWVTPKLDGSGIAGVKRRQIMELSAKAGQPIREMKITINDLLNAQAVCLSNAL
MGIVPVIQYQSHCYPESSLLHIQKLQSLVEKGEVFNAD

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=246, Percent_Identity=39.8373983739837, Blast_Score=177, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 31096; Mature: 31096

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLINGTESTTIAADDRGLAYGDGLFSTIKVERGIVQLWDYHLQRLQLGAKKLFFPEVDWL
CEECCCCCCEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LLSSELHYLAKTVAEQPFAVIKVMLTRGSGGRGYSIQGCSSPQRILSVHPYPVFYQQWQR
HHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEECCCCCHHHHEECCCCHHHHHHHHH
DGLKVIQCRQKLAINRQLAGLKTLNRLEQILIKHELEAQDAFEGIVCDNDGHVIEACSAN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEECCCCCEEEECCCE
LFLKLKNHWVTPKLDGSGIAGVKRRQIMELSAKAGQPIREMKITINDLLNAQAVCLSNAL
EEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHH
MGIVPVIQYQSHCYPESSLLHIQKLQSLVEKGEVFNAD
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLINGTESTTIAADDRGLAYGDGLFSTIKVERGIVQLWDYHLQRLQLGAKKLFFPEVDWL
CEECCCCCCEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LLSSELHYLAKTVAEQPFAVIKVMLTRGSGGRGYSIQGCSSPQRILSVHPYPVFYQQWQR
HHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEECCCCCHHHHEECCCCHHHHHHHHH
DGLKVIQCRQKLAINRQLAGLKTLNRLEQILIKHELEAQDAFEGIVCDNDGHVIEACSAN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEECCCCCEEEECCCE
LFLKLKNHWVTPKLDGSGIAGVKRRQIMELSAKAGQPIREMKITINDLLNAQAVCLSNAL
EEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHH
MGIVPVIQYQSHCYPESSLLHIQKLQSLVEKGEVFNAD
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644759; 8905232; 9278503; 2071583; 2251281; 10876155 [H]