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The map label for this gene is clpB-1 [H]

Identifier: 119944798

GI number: 119944798

Start: 1311798

End: 1314284

Strand: Direct

Name: clpB-1 [H]

Synonym: Ping_1040

Alternate gene names: 119944798

Gene position: 1311798-1314284 (Clockwise)

Preceding gene: 119944793

Following gene: 119944803

Centisome position: 28.77

GC content: 45.56

Gene sequence:

>2487_bases
ATGTCCGATTGGAATAACCCGGCGGCCAAAGGAGCCATGTTACATAATTATGTTCAGAAGAGTACCCAAAAGGTGATTGG
CTGTTTGGAGATTGCTTTTGCCGAGTTAGGAAGCTTACGGCTGAATATATTGACGTCCGATTTTTTGCTGGTTGCGTTAC
TTTCTCAACCGGACAGCGAAGCGCACAAAATTTTGCAGGAGTTATTGCCAAATGAAGATGATGCTCCATTGCGTATCGTT
GGTCAGATAAGGCAAAAATACCCCCCCGCAAGTAACGTCCAGGCAAGGCAAATTTTGGCTTCTCAAGAGATAGTCGAAGT
ATTTCGAGTTGCCTACGACGAGGCTAAAGACTTTGGCGATGACTATATTGGTACAGGCACTTTATTTCTTGCTTTTTTTC
ATAAGGATGCGGGGCATGTTGCTGATATTTTGAATAATGAAGGTATTCGCGTTGACCAGGCGCGTCAAGCATTAAAGCAT
ATTCGACGGGGGCATCAGCTTAATAGTCAAGATGCGGAAGGAAAACCAGATATATTGGATATCTATACTAAAGATCTCAC
CGAGATGGCGCGCAAAGGGGAGTTAGATCCTGTTATTGGTCGGGAGGAGGAGATCGAATTGATTATTCAAACCTTGTCCC
GGCGTAAGAAAAATAACCCTGCCCTGATTGGTGAACCCGGGGTAGGTAAAACGGTTATTGTCGAAGGTTTGGCACAACGG
ATTGTGGCTGCTGATGTGCCCGATAGTCAGCTAAATAAGCGTTTACTTGCGCTGGATATGGGAGAGCTGGTGGCCGGGGC
TTCAATGCGCGGTGAATTTGAAGAGCGCTTAAAATCTGTGCGTGATGCCGTTATTGAGGCGGGAGGCAAGGTTATTCTGT
TTATTGATGAATTGCATACCGTGGTTGGCGCTAATGCCGGATCCGGTGGTATTGATGCTCCGAGTCTGTTGAAAACCGCG
CTGGCTCAGGGAACCCTGCAGGTTATAGGGGCTGATACTTTGGATGAATATCAAAAATATATAGAAACAGATAAAGCCCT
TGAGCGGCGCTTTCATCCTATTTTAGTACGGGAGCCGAGTATTGAGGAAACCATTGCTATTTTGCAGGGCGCGGCTCCCC
GTTATGAAAAGCACCATGATATTCATTATGCGTTACCAGCATTCGAAGCTGCAGCACGACTTTCTGAGCGTTATATTGCG
GATCGCTGTTTACCCGATAAGGCGGTTGACTTGATTGATGAAGCAGGCGCGCGGAAACATCTTCGTCTTACCGCTATTCC
TCAAAATTTGCGGGATCTTGAACGTAAGCATCAAGGGTTATTACGCGATAAGACCGGCGCTTTTAATGCGCAAAATTTTG
AGCAGGTAGCAGCAACGCAGATGGAGATTTTAAAGAGCGATCAAAAGCTTAAAGAGGCACGCAGTGATTGGCAACAGGGG
CGGGCCAAGGAAGATGCGATGGTGACATCGGATGATATTGCCGAAGTAGTAGCACGCTGGACAGGTATTCCCGTTGCGAG
AATGGTTGAATCGGAGTCTGAAAAACTGGCCCGAATGGAAGAAAAATTGCATCAGCGGATCGTTGGCCAGGAAGATGCTG
TCCGCGCTGTTGCAGATGCCATTCGTCGCAATCGGGCCGGTATTACAAACAGCCGACGTCCTATTGGCTCATTTCTTTTT
CTGGGCCCTACTGGTGTCGGGAAAACTGAACTCGCCCGTGCCTTGGCTGCCTTTTTGTTAGATGATGAAACAAGAATAAT
TCGTCTTGATATGTCGGAGTATATGGAGAGACATGAAGTCTCTAAAATGATTGGCGCACCACCAGGGTATATCGGTTATG
GTGAAGGAGGGCAATTAACAGAACGTGTACGTCATAACCCCTATACAGTGGTATTGCTGGATGAGATGGAGAAAGCTCAC
CCGGATGTGTTTAATATGTTACTGCAAATTCTTGAAGATGGGCAACTAACGGATGCTAAAGGGCGTAAAGTTTCCTTTCG
CAATACCGTTATTATAGGAACTTCTAATCTGGGCACCGGGTCACTCTCCCCTGACAAGCGTCCGATCGGATTTATTCATT
CTGATTCGCTAAACTATAAGGAAACACAAGATTTGGTGATGCACGAAGTTAAGAAGTTCTTTAAACCAGAGTTTCTTAAC
CGGCTTGATGACATCATCGTCTTTCATTATTTAGAAAAAGAACATGTCCGTCAGATAGCACAGATGTTTGTCGCTGAATT
AGTCGAACGAATGAAACTGAGGGGCATTGTGCTTGAAGTCGATAATGCTGTGATTGATAAACTCTCGGCAGACGGTTTTG
ATCCTATTTATGGTGCGCGACCCTTAAGACGTGAAGTGGAGCGTCAAATAGAAAATGTATTAGCAATGAAAGTTGTGCGG
AATGAATTCTCAGATAACAGTGTGGTTCAAGTTAAGATGCAGGATAAGGAGATTGTTTTTCTCACCGAGCAGAAGATGAC
TAAATAG

Upstream 100 bases:

>100_bases
ACAGTGCAGGGCGAATTAAGGATACTAGAATTATATGTAATATGTTTTTGGAGGATTAACCCATTCAAGTTCATGAAATT
ATAACGTAAGGAGTTTTATT

Downstream 100 bases:

>100_bases
CGTTTTATTTTTGTAGTAAATAAAATGACAAACCTTTACGGGTTTGCCATTTTTAAAATATTAAATTTACTGACGCACAC
CTTCAACGTTTAATTCCATG

Product: chaperone endopeptidase Clp ATP-binding chain B,ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 828; Mature: 827

Protein sequence:

>828_residues
MSDWNNPAAKGAMLHNYVQKSTQKVIGCLEIAFAELGSLRLNILTSDFLLVALLSQPDSEAHKILQELLPNEDDAPLRIV
GQIRQKYPPASNVQARQILASQEIVEVFRVAYDEAKDFGDDYIGTGTLFLAFFHKDAGHVADILNNEGIRVDQARQALKH
IRRGHQLNSQDAEGKPDILDIYTKDLTEMARKGELDPVIGREEEIELIIQTLSRRKKNNPALIGEPGVGKTVIVEGLAQR
IVAADVPDSQLNKRLLALDMGELVAGASMRGEFEERLKSVRDAVIEAGGKVILFIDELHTVVGANAGSGGIDAPSLLKTA
LAQGTLQVIGADTLDEYQKYIETDKALERRFHPILVREPSIEETIAILQGAAPRYEKHHDIHYALPAFEAAARLSERYIA
DRCLPDKAVDLIDEAGARKHLRLTAIPQNLRDLERKHQGLLRDKTGAFNAQNFEQVAATQMEILKSDQKLKEARSDWQQG
RAKEDAMVTSDDIAEVVARWTGIPVARMVESESEKLARMEEKLHQRIVGQEDAVRAVADAIRRNRAGITNSRRPIGSFLF
LGPTGVGKTELARALAAFLLDDETRIIRLDMSEYMERHEVSKMIGAPPGYIGYGEGGQLTERVRHNPYTVVLLDEMEKAH
PDVFNMLLQILEDGQLTDAKGRKVSFRNTVIIGTSNLGTGSLSPDKRPIGFIHSDSLNYKETQDLVMHEVKKFFKPEFLN
RLDDIIVFHYLEKEHVRQIAQMFVAELVERMKLRGIVLEVDNAVIDKLSADGFDPIYGARPLRREVERQIENVLAMKVVR
NEFSDNSVVQVKMQDKEIVFLTEQKMTK

Sequences:

>Translated_828_residues
MSDWNNPAAKGAMLHNYVQKSTQKVIGCLEIAFAELGSLRLNILTSDFLLVALLSQPDSEAHKILQELLPNEDDAPLRIV
GQIRQKYPPASNVQARQILASQEIVEVFRVAYDEAKDFGDDYIGTGTLFLAFFHKDAGHVADILNNEGIRVDQARQALKH
IRRGHQLNSQDAEGKPDILDIYTKDLTEMARKGELDPVIGREEEIELIIQTLSRRKKNNPALIGEPGVGKTVIVEGLAQR
IVAADVPDSQLNKRLLALDMGELVAGASMRGEFEERLKSVRDAVIEAGGKVILFIDELHTVVGANAGSGGIDAPSLLKTA
LAQGTLQVIGADTLDEYQKYIETDKALERRFHPILVREPSIEETIAILQGAAPRYEKHHDIHYALPAFEAAARLSERYIA
DRCLPDKAVDLIDEAGARKHLRLTAIPQNLRDLERKHQGLLRDKTGAFNAQNFEQVAATQMEILKSDQKLKEARSDWQQG
RAKEDAMVTSDDIAEVVARWTGIPVARMVESESEKLARMEEKLHQRIVGQEDAVRAVADAIRRNRAGITNSRRPIGSFLF
LGPTGVGKTELARALAAFLLDDETRIIRLDMSEYMERHEVSKMIGAPPGYIGYGEGGQLTERVRHNPYTVVLLDEMEKAH
PDVFNMLLQILEDGQLTDAKGRKVSFRNTVIIGTSNLGTGSLSPDKRPIGFIHSDSLNYKETQDLVMHEVKKFFKPEFLN
RLDDIIVFHYLEKEHVRQIAQMFVAELVERMKLRGIVLEVDNAVIDKLSADGFDPIYGARPLRREVERQIENVLAMKVVR
NEFSDNSVVQVKMQDKEIVFLTEQKMTK
>Mature_827_residues
SDWNNPAAKGAMLHNYVQKSTQKVIGCLEIAFAELGSLRLNILTSDFLLVALLSQPDSEAHKILQELLPNEDDAPLRIVG
QIRQKYPPASNVQARQILASQEIVEVFRVAYDEAKDFGDDYIGTGTLFLAFFHKDAGHVADILNNEGIRVDQARQALKHI
RRGHQLNSQDAEGKPDILDIYTKDLTEMARKGELDPVIGREEEIELIIQTLSRRKKNNPALIGEPGVGKTVIVEGLAQRI
VAADVPDSQLNKRLLALDMGELVAGASMRGEFEERLKSVRDAVIEAGGKVILFIDELHTVVGANAGSGGIDAPSLLKTAL
AQGTLQVIGADTLDEYQKYIETDKALERRFHPILVREPSIEETIAILQGAAPRYEKHHDIHYALPAFEAAARLSERYIAD
RCLPDKAVDLIDEAGARKHLRLTAIPQNLRDLERKHQGLLRDKTGAFNAQNFEQVAATQMEILKSDQKLKEARSDWQQGR
AKEDAMVTSDDIAEVVARWTGIPVARMVESESEKLARMEEKLHQRIVGQEDAVRAVADAIRRNRAGITNSRRPIGSFLFL
GPTGVGKTELARALAAFLLDDETRIIRLDMSEYMERHEVSKMIGAPPGYIGYGEGGQLTERVRHNPYTVVLLDEMEKAHP
DVFNMLLQILEDGQLTDAKGRKVSFRNTVIIGTSNLGTGSLSPDKRPIGFIHSDSLNYKETQDLVMHEVKKFFKPEFLNR
LDDIIVFHYLEKEHVRQIAQMFVAELVERMKLRGIVLEVDNAVIDKLSADGFDPIYGARPLRREVERQIENVLAMKVVRN
EFSDNSVVQVKMQDKEIVFLTEQKMTK

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=333, Percent_Identity=35.7357357357357, Blast_Score=198, Evalue=2e-50,
Organism=Escherichia coli, GI1788943, Length=782, Percent_Identity=46.5473145780051, Blast_Score=676, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=808, Percent_Identity=38.3663366336634, Blast_Score=503, Evalue=1e-143,
Organism=Saccharomyces cerevisiae, GI6320464, Length=736, Percent_Identity=41.5760869565217, Blast_Score=533, Evalue=1e-152,
Organism=Saccharomyces cerevisiae, GI6323002, Length=843, Percent_Identity=33.8078291814947, Blast_Score=425, Evalue=1e-119,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 92743; Mature: 92612

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDWNNPAAKGAMLHNYVQKSTQKVIGCLEIAFAELGSLRLNILTSDFLLVALLSQPDSE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCHH
AHKILQELLPNEDDAPLRIVGQIRQKYPPASNVQARQILASQEIVEVFRVAYDEAKDFGD
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DYIGTGTLFLAFFHKDAGHVADILNNEGIRVDQARQALKHIRRGHQLNSQDAEGKPDILD
CCCCHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
IYTKDLTEMARKGELDPVIGREEEIELIIQTLSRRKKNNPALIGEPGVGKTVIVEGLAQR
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHH
IVAADVPDSQLNKRLLALDMGELVAGASMRGEFEERLKSVRDAVIEAGGKVILFIDELHT
HHHCCCCHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHH
VVGANAGSGGIDAPSLLKTALAQGTLQVIGADTLDEYQKYIETDKALERRFHPILVREPS
HHCCCCCCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEECCC
IEETIAILQGAAPRYEKHHDIHYALPAFEAAARLSERYIADRCLPDKAVDLIDEAGARKH
HHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCE
LRLTAIPQNLRDLERKHQGLLRDKTGAFNAQNFEQVAATQMEILKSDQKLKEARSDWQQG
EEEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RAKEDAMVTSDDIAEVVARWTGIPVARMVESESEKLARMEEKLHQRIVGQEDAVRAVADA
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IRRNRAGITNSRRPIGSFLFLGPTGVGKTELARALAAFLLDDETRIIRLDMSEYMERHEV
HHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHH
SKMIGAPPGYIGYGEGGQLTERVRHNPYTVVLLDEMEKAHPDVFNMLLQILEDGQLTDAK
HHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEEECCHHHCCHHHHHHHHHHHCCCCCCCCC
GRKVSFRNTVIIGTSNLGTGSLSPDKRPIGFIHSDSLNYKETQDLVMHEVKKFFKPEFLN
CCEEEECCEEEEECCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCHHHHH
RLDDIIVFHYLEKEHVRQIAQMFVAELVERMKLRGIVLEVDNAVIDKLSADGFDPIYGAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCCCCCC
PLRREVERQIENVLAMKVVRNEFSDNSVVQVKMQDKEIVFLTEQKMTK
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECCCCCC
>Mature Secondary Structure 
SDWNNPAAKGAMLHNYVQKSTQKVIGCLEIAFAELGSLRLNILTSDFLLVALLSQPDSE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCHH
AHKILQELLPNEDDAPLRIVGQIRQKYPPASNVQARQILASQEIVEVFRVAYDEAKDFGD
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DYIGTGTLFLAFFHKDAGHVADILNNEGIRVDQARQALKHIRRGHQLNSQDAEGKPDILD
CCCCHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
IYTKDLTEMARKGELDPVIGREEEIELIIQTLSRRKKNNPALIGEPGVGKTVIVEGLAQR
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHH
IVAADVPDSQLNKRLLALDMGELVAGASMRGEFEERLKSVRDAVIEAGGKVILFIDELHT
HHHCCCCHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHH
VVGANAGSGGIDAPSLLKTALAQGTLQVIGADTLDEYQKYIETDKALERRFHPILVREPS
HHCCCCCCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEECCC
IEETIAILQGAAPRYEKHHDIHYALPAFEAAARLSERYIADRCLPDKAVDLIDEAGARKH
HHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCE
LRLTAIPQNLRDLERKHQGLLRDKTGAFNAQNFEQVAATQMEILKSDQKLKEARSDWQQG
EEEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RAKEDAMVTSDDIAEVVARWTGIPVARMVESESEKLARMEEKLHQRIVGQEDAVRAVADA
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IRRNRAGITNSRRPIGSFLFLGPTGVGKTELARALAAFLLDDETRIIRLDMSEYMERHEV
HHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHH
SKMIGAPPGYIGYGEGGQLTERVRHNPYTVVLLDEMEKAHPDVFNMLLQILEDGQLTDAK
HHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEEECCHHHCCHHHHHHHHHHHCCCCCCCCC
GRKVSFRNTVIIGTSNLGTGSLSPDKRPIGFIHSDSLNYKETQDLVMHEVKKFFKPEFLN
CCEEEECCEEEEECCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCHHHHH
RLDDIIVFHYLEKEHVRQIAQMFVAELVERMKLRGIVLEVDNAVIDKLSADGFDPIYGAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCCCCCC
PLRREVERQIENVLAMKVVRNEFSDNSVVQVKMQDKEIVFLTEQKMTK
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]