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The map label for this gene is scrR [H]

Identifier: 119944732

GI number: 119944732

Start: 1221829

End: 1222842

Strand: Direct

Name: scrR [H]

Synonym: Ping_0973

Alternate gene names: 119944732

Gene position: 1221829-1222842 (Clockwise)

Preceding gene: 119944727

Following gene: 119944733

Centisome position: 26.8

GC content: 42.21

Gene sequence:

>1014_bases
ATGACAGGCCTGCATGACGTAGCAAAATTATCCGGGGTATCAAAATCGACCGTTTCTCGCGTGATTAATAATGAGTCCGG
TGTGAAAGCGAGCACCAAAGAAAAGGTTCAGAAAGCAATCGACGCGTGCGGTTATATCGCAAATCAAGTTGCCAGGGATC
TGCAATCTCAGAAAACCAATCTTATTGGCGTGATAGTCCCGCGTATGTATTCAAATGCGACTGCGAAAGGCCTTGATGGT
CTAAGTTCGATTATTGATCAAGCGGGTAAGTACGTTTTATTGGCAAACAGTCAGCAAAATCACGCACAAGAGATTGAATA
TATAAAGCGTTTTAATCAAAAACGTGTTGAAGGAATATTACTTTACGCAACCCATTTAGATTCGGCATTGGTTGATGCGA
TCAAACAATCTAAAGCCCCCGTGGTATTAATCGGGCAGGACGGATCTCTGTTTAATATTCCCAGTGTCATTTACGATGAT
CTGAGTGTTGGTTTCAGCGCAGGGCAGAGACTGTTTGGCGCGGGCGCATCAAATATTGGTTTTATTGGGGTCAACAGTCA
GGATATTGCTGTGGACCAGTGCCGTTTTGAAGGATTGAGACAAGCATTGCAGCATACAAAGCAGATCTCGCCACTTTTTC
ACAGCCGTGGCGCGTTTTCAATTGAATCTGGTTACCAGCAGACTAAACAGCTATTAATTGATTGGCCACAATTAGACGGT
TTGTTTTGTGCGACAGACAGAATCGCAATAGGGGCAATGAAGGCAATCTCTGAATCGGGTAAAGTGCCGGGGAAAGAGAT
TAAAGTACTGGGAGTGGGTAATGACGAGTTAAGTCAAGTATCTACCCCAAGCTTATCAACATTTTCTTATGCATTTGATT
TAACAGGAGAAAAGTCAGCTAATATGTTGTTGGATTTAATTGAAAATAAACAGTCAAGCGTCAGTAAACTGGTGATGAGC
TTTGAAATTATCGATCGGGAAAGTTGTTACTTGTCAGAAAATAAAACGTCTTAG

Upstream 100 bases:

>100_bases
TTTTTGCTTAAAAAGCAATCAAAAAAGCTACTTGTTACGCTTAACTTCTTATTTTTTGTTAACATACCTGCAAACGATCC
CAAATTATAGGAAACAAGCC

Downstream 100 bases:

>100_bases
TTCGTTTATTGCGGGTTTGTATAAACAGCAATCAAAGATTTTTTTGTTTAAATAAAAAATCATCTTATTGCAAATATGCC
TTTATTTTTATATTCTGCAA

Product: sucrose operon repressor ScrR

Products: NA

Alternate protein names: Scr operon regulatory protein [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTGLHDVAKLSGVSKSTVSRVINNESGVKASTKEKVQKAIDACGYIANQVARDLQSQKTNLIGVIVPRMYSNATAKGLDG
LSSIIDQAGKYVLLANSQQNHAQEIEYIKRFNQKRVEGILLYATHLDSALVDAIKQSKAPVVLIGQDGSLFNIPSVIYDD
LSVGFSAGQRLFGAGASNIGFIGVNSQDIAVDQCRFEGLRQALQHTKQISPLFHSRGAFSIESGYQQTKQLLIDWPQLDG
LFCATDRIAIGAMKAISESGKVPGKEIKVLGVGNDELSQVSTPSLSTFSYAFDLTGEKSANMLLDLIENKQSSVSKLVMS
FEIIDRESCYLSENKTS

Sequences:

>Translated_337_residues
MTGLHDVAKLSGVSKSTVSRVINNESGVKASTKEKVQKAIDACGYIANQVARDLQSQKTNLIGVIVPRMYSNATAKGLDG
LSSIIDQAGKYVLLANSQQNHAQEIEYIKRFNQKRVEGILLYATHLDSALVDAIKQSKAPVVLIGQDGSLFNIPSVIYDD
LSVGFSAGQRLFGAGASNIGFIGVNSQDIAVDQCRFEGLRQALQHTKQISPLFHSRGAFSIESGYQQTKQLLIDWPQLDG
LFCATDRIAIGAMKAISESGKVPGKEIKVLGVGNDELSQVSTPSLSTFSYAFDLTGEKSANMLLDLIENKQSSVSKLVMS
FEIIDRESCYLSENKTS
>Mature_336_residues
TGLHDVAKLSGVSKSTVSRVINNESGVKASTKEKVQKAIDACGYIANQVARDLQSQKTNLIGVIVPRMYSNATAKGLDGL
SSIIDQAGKYVLLANSQQNHAQEIEYIKRFNQKRVEGILLYATHLDSALVDAIKQSKAPVVLIGQDGSLFNIPSVIYDDL
SVGFSAGQRLFGAGASNIGFIGVNSQDIAVDQCRFEGLRQALQHTKQISPLFHSRGAFSIESGYQQTKQLLIDWPQLDGL
FCATDRIAIGAMKAISESGKVPGKEIKVLGVGNDELSQVSTPSLSTFSYAFDLTGEKSANMLLDLIENKQSSVSKLVMSF
EIIDRESCYLSENKTS

Specific function: Negative regulator of scrB expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=330, Percent_Identity=27.8787878787879, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787948, Length=334, Percent_Identity=29.0419161676647, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786540, Length=340, Percent_Identity=28.5294117647059, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790689, Length=301, Percent_Identity=26.9102990033223, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1790715, Length=331, Percent_Identity=27.7945619335347, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1789068, Length=291, Percent_Identity=27.8350515463918, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787580, Length=320, Percent_Identity=27.8125, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1790194, Length=331, Percent_Identity=26.8882175226586, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI48994940, Length=322, Percent_Identity=25.4658385093168, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788474, Length=294, Percent_Identity=28.2312925170068, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1789202, Length=292, Percent_Identity=26.027397260274, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1787906, Length=267, Percent_Identity=23.9700374531835, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786268, Length=280, Percent_Identity=23.5714285714286, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36460; Mature: 36329

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLHDVAKLSGVSKSTVSRVINNESGVKASTKEKVQKAIDACGYIANQVARDLQSQKTN
CCCHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LIGVIVPRMYSNATAKGLDGLSSIIDQAGKYVLLANSQQNHAQEIEYIKRFNQKRVEGIL
EEEEEECHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHCEEE
LYATHLDSALVDAIKQSKAPVVLIGQDGSLFNIPSVIYDDLSVGFSAGQRLFGAGASNIG
EEHHHHHHHHHHHHHHCCCCEEEEECCCCEECCHHHHHHHHHHHHHHCHHHHCCCCCCCE
FIGVNSQDIAVDQCRFEGLRQALQHTKQISPLFHSRGAFSIESGYQQTKQLLIDWPQLDG
EEECCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCC
LFCATDRIAIGAMKAISESGKVPGKEIKVLGVGNDELSQVSTPSLSTFSYAFDLTGEKSA
EEEECCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHCCCCCCCCEEEEEECCCCCHH
NMLLDLIENKQSSVSKLVMSFEIIDRESCYLSENKTS
HHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TGLHDVAKLSGVSKSTVSRVINNESGVKASTKEKVQKAIDACGYIANQVARDLQSQKTN
CCHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LIGVIVPRMYSNATAKGLDGLSSIIDQAGKYVLLANSQQNHAQEIEYIKRFNQKRVEGIL
EEEEEECHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHCEEE
LYATHLDSALVDAIKQSKAPVVLIGQDGSLFNIPSVIYDDLSVGFSAGQRLFGAGASNIG
EEHHHHHHHHHHHHHHCCCCEEEEECCCCEECCHHHHHHHHHHHHHHCHHHHCCCCCCCE
FIGVNSQDIAVDQCRFEGLRQALQHTKQISPLFHSRGAFSIESGYQQTKQLLIDWPQLDG
EEECCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCC
LFCATDRIAIGAMKAISESGKVPGKEIKVLGVGNDELSQVSTPSLSTFSYAFDLTGEKSA
EEEECCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHCCCCCCCCEEEEEECCCCCHH
NMLLDLIENKQSSVSKLVMSFEIIDRESCYLSENKTS
HHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550467 [H]