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The map label for this gene is ppnK [H]

Identifier: 119944676

GI number: 119944676

Start: 1145784

End: 1146683

Strand: Reverse

Name: ppnK [H]

Synonym: Ping_0915

Alternate gene names: 119944676

Gene position: 1146683-1145784 (Counterclockwise)

Preceding gene: 119944681

Following gene: 119944675

Centisome position: 25.15

GC content: 39.11

Gene sequence:

>900_bases
ATGGGTGCCCAGCACGACAATTTAATTGAATTTAAAACGATTGGTTTGATTGCCAAAACTCAACATCCCGATGCTAAACT
GACATTATTAGCTTTATATCGTTTTTTGAAAGCTAAAGGCGTAAAGCTGGTCGTTGATCAGCGCATCGCCGATGAACTTC
CTATGAATGGATTCGACCGCGCGGACTTGGTTGGTATCGGAAGCCGTTGTGATTTAGCGATAGTGATAGGTGGAGATGGT
TACATGCTTGGCGCTGCCCGTGTATTGTCACGTTTTGACATTGCTGTTATTGGTGTAAACCGGGGTAACTTAGGCTTTTT
AACGGATCTTGATCCGGATAATTTTGAGCAGCCATTAGAGCAAGTATTATTAGGTAATTACCAAATAGAAAAACGTTTTT
TATTAGAAGCGCAAGTACATCGCCATGGCGATATGAAAAGCTCCAATACTGCAGTTAATGAAGCTGTTTTACATCCAGAT
AAAATTGCGCATATGCTTGAATTTGAAGTCTATGTAAACGATGACTTCATGTTGAATCAACGCGCTGACGGTCTAATTAT
TGCAACACCAACGGGTTCAACAGCATACTCTCTATCAGGGGGTGGCCCAATTTTAACGCCAAATTTAGATGCCATTAGTC
TGTTACCTATGTTCCCCCATACATTAAATAGCCGCCCCATTGTTATTGACGCTAATAGTTGTGTGCGTTTGAAAATTGCA
CAATCGAATAAAAGTGAAATGCAAATAAGCTGTGACAGCCATGTAAATTTATCCGTTCTACCTGGGGATGAAATAATAAT
CAAAAAAAGCCAAGATCAATTAAAATTAGTTCACCCAAAAAACTATAACTATTTCCATGTCTTACAAAATAAATTGGGGT
GGGGCAATAAGCTTTATTAA

Upstream 100 bases:

>100_bases
CCAATAAATCGTAACAAATTGACCTGAAAGAAAATAATTACTGCTAGAACATTATATCAGGTTATCCTTTAACTATAATA
TTAACTAATAAAGGAACTCT

Downstream 100 bases:

>100_bases
CTGGTCAGAAAAAAATAGAAGAAAATTCAACACATCTCATCTTTACTGTTTAAAAAAACAGTATTAGACTGTGCAAATAA
ACAGTGTTAATACTCAGTCT

Product: NAD(+) kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MGAQHDNLIEFKTIGLIAKTQHPDAKLTLLALYRFLKAKGVKLVVDQRIADELPMNGFDRADLVGIGSRCDLAIVIGGDG
YMLGAARVLSRFDIAVIGVNRGNLGFLTDLDPDNFEQPLEQVLLGNYQIEKRFLLEAQVHRHGDMKSSNTAVNEAVLHPD
KIAHMLEFEVYVNDDFMLNQRADGLIIATPTGSTAYSLSGGGPILTPNLDAISLLPMFPHTLNSRPIVIDANSCVRLKIA
QSNKSEMQISCDSHVNLSVLPGDEIIIKKSQDQLKLVHPKNYNYFHVLQNKLGWGNKLY

Sequences:

>Translated_299_residues
MGAQHDNLIEFKTIGLIAKTQHPDAKLTLLALYRFLKAKGVKLVVDQRIADELPMNGFDRADLVGIGSRCDLAIVIGGDG
YMLGAARVLSRFDIAVIGVNRGNLGFLTDLDPDNFEQPLEQVLLGNYQIEKRFLLEAQVHRHGDMKSSNTAVNEAVLHPD
KIAHMLEFEVYVNDDFMLNQRADGLIIATPTGSTAYSLSGGGPILTPNLDAISLLPMFPHTLNSRPIVIDANSCVRLKIA
QSNKSEMQISCDSHVNLSVLPGDEIIIKKSQDQLKLVHPKNYNYFHVLQNKLGWGNKLY
>Mature_298_residues
GAQHDNLIEFKTIGLIAKTQHPDAKLTLLALYRFLKAKGVKLVVDQRIADELPMNGFDRADLVGIGSRCDLAIVIGGDGY
MLGAARVLSRFDIAVIGVNRGNLGFLTDLDPDNFEQPLEQVLLGNYQIEKRFLLEAQVHRHGDMKSSNTAVNEAVLHPDK
IAHMLEFEVYVNDDFMLNQRADGLIIATPTGSTAYSLSGGGPILTPNLDAISLLPMFPHTLNSRPIVIDANSCVRLKIAQ
SNKSEMQISCDSHVNLSVLPGDEIIIKKSQDQLKLVHPKNYNYFHVLQNKLGWGNKLY

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=265, Percent_Identity=27.1698113207547, Blast_Score=88, Evalue=9e-18,
Organism=Escherichia coli, GI1788968, Length=289, Percent_Identity=55.7093425605536, Blast_Score=345, Evalue=3e-96,
Organism=Saccharomyces cerevisiae, GI6320794, Length=242, Percent_Identity=28.5123966942149, Blast_Score=130, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6322509, Length=239, Percent_Identity=29.2887029288703, Blast_Score=114, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6325068, Length=212, Percent_Identity=32.5471698113208, Blast_Score=106, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28573828, Length=253, Percent_Identity=27.6679841897233, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573826, Length=253, Percent_Identity=27.6679841897233, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28573830, Length=253, Percent_Identity=27.6679841897233, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI161077047, Length=253, Percent_Identity=27.6679841897233, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28573832, Length=256, Percent_Identity=27.34375, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI20129957, Length=278, Percent_Identity=24.1007194244604, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24653422, Length=278, Percent_Identity=24.1007194244604, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281363321, Length=278, Percent_Identity=24.1007194244604, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281363323, Length=278, Percent_Identity=24.1007194244604, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24653424, Length=278, Percent_Identity=24.1007194244604, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 33056; Mature: 32924

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAQHDNLIEFKTIGLIAKTQHPDAKLTLLALYRFLKAKGVKLVVDQRIADELPMNGFDR
CCCCCCCEEEEEEEEEEEECCCCCCEEHHHHHHHHHHHCCCEEEEECHHHHHCCCCCCCC
ADLVGIGSRCDLAIVIGGDGYMLGAARVLSRFDIAVIGVNRGNLGFLTDLDPDNFEQPLE
CEEEEECCCCCEEEEECCCCEEEHHHHHHHHCCEEEEEECCCCEEEEECCCCCCHHHHHH
QVLLGNYQIEKRFLLEAQVHRHGDMKSSNTAVNEAVLHPDKIAHMLEFEVYVNDDFMLNQ
HHHHCCEEEEHEEEEEHHHHHCCCCCCCCCHHHHHHCCHHHHHEEEEEEEEECCCEEEEC
RADGLIIATPTGSTAYSLSGGGPILTPNLDAISLLPMFPHTLNSRPIVIDANSCVRLKIA
CCCEEEEECCCCCCEEEECCCCCEECCCCCEEEEEECCCCCCCCCCEEEECCCEEEEEEE
QSNKSEMQISCDSHVNLSVLPGDEIIIKKSQDQLKLVHPKNYNYFHVLQNKLGWGNKLY
CCCCCEEEEEECCCCEEEEECCCEEEEEECCCCEEEECCCCCCEEEEEHHCCCCCCCCC
>Mature Secondary Structure 
GAQHDNLIEFKTIGLIAKTQHPDAKLTLLALYRFLKAKGVKLVVDQRIADELPMNGFDR
CCCCCCEEEEEEEEEEEECCCCCCEEHHHHHHHHHHHCCCEEEEECHHHHHCCCCCCCC
ADLVGIGSRCDLAIVIGGDGYMLGAARVLSRFDIAVIGVNRGNLGFLTDLDPDNFEQPLE
CEEEEECCCCCEEEEECCCCEEEHHHHHHHHCCEEEEEECCCCEEEEECCCCCCHHHHHH
QVLLGNYQIEKRFLLEAQVHRHGDMKSSNTAVNEAVLHPDKIAHMLEFEVYVNDDFMLNQ
HHHHCCEEEEHEEEEEHHHHHCCCCCCCCCHHHHHHCCHHHHHEEEEEEEEECCCEEEEC
RADGLIIATPTGSTAYSLSGGGPILTPNLDAISLLPMFPHTLNSRPIVIDANSCVRLKIA
CCCEEEEECCCCCCEEEECCCCCEECCCCCEEEEEECCCCCCCCCCEEEECCCEEEEEEE
QSNKSEMQISCDSHVNLSVLPGDEIIIKKSQDQLKLVHPKNYNYFHVLQNKLGWGNKLY
CCCCCEEEEEECCCCEEEEECCCEEEEEECCCCEEEECCCCCCEEEEEHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA