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The map label for this gene is mtnN

Identifier: 119944681

GI number: 119944681

Start: 1152198

End: 1152893

Strand: Reverse

Name: mtnN

Synonym: Ping_0920

Alternate gene names: 119944681

Gene position: 1152893-1152198 (Counterclockwise)

Preceding gene: 119944684

Following gene: 119944676

Centisome position: 25.28

GC content: 39.94

Gene sequence:

>696_bases
ATGAAAATAGGCATTATTGGTGCGATGGATGAAGAAGTCAGCATCCTTAAAGCGAAGTTAAATAACATGGAAACAACGAT
CATTGCAGGTTGTGAATTTTACCAGGGTGAATTAAATGGTAAACAGGTTATCTTAACCAAATCAGGCATAGGTAAAGTTG
CTGCTGCCGTGGCAACGACACTGTTACTGGAAAGATTTAATCCAGGTCAGGTAATTAATACGGGTTCCGCTGGGGGTTAC
GATACAACGCTTAATGTAGGCGACATTGTGATATCAACAGAAGTACGTTTTCATGATGTCGATTTAACTGCATTTGGTTA
TGAAATTGGCCAAATGGCGCAATTGCCTGCCGCTTTTCCAGCAGATAAAAATCTGATTTTCGCAGCACAAAAAGCCGCTG
AAACGATTACCCATTTAAAAACCATTCAGGGATTAATCTGTACGGGTGATATTTTTATGGCGGATCCAACAAAAGCTGAA
ATAGCACGTCATAATTTCCCAACAATGGCGGCATGTGAAATGGAAGCTGCGGCCATTGCACAGGTTTGTTACCAGTTTAA
AGTGCCTTTTGTGATCATCCGTTCACTCTCGGATATTGCCGGTAAAAAATCAGAATTATCCTTTGAGCAATACCTGCCGA
TTGCTGCTAAAAATGCATCAATACTTGTTGAAGAAATTATCAATAACTTAAACTAG

Upstream 100 bases:

>100_bases
ATATTACACATTTAAGAGACACAAAAAAACCATAGAGTGCCGATATAAGGCACTTTATGTTAGCATTAGCATTATTTTTT
AATGACAAAGAGCAGAACAG

Downstream 100 bases:

>100_bases
TTTTTACTGTTTTTTATTCGCTTTATTATACATATAAAAAAAGCCCTAATCTGTTACCAGAGAAGGGCTTTAATATTTTC
ATGTCCTACTTATGACAGTA

Product: methylthioadenosine nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKIGIIGAMDEEVSILKAKLNNMETTIIAGCEFYQGELNGKQVILTKSGIGKVAAAVATTLLLERFNPGQVINTGSAGGY
DTTLNVGDIVISTEVRFHDVDLTAFGYEIGQMAQLPAAFPADKNLIFAAQKAAETITHLKTIQGLICTGDIFMADPTKAE
IARHNFPTMAACEMEAAAIAQVCYQFKVPFVIIRSLSDIAGKKSELSFEQYLPIAAKNASILVEEIINNLN

Sequences:

>Translated_231_residues
MKIGIIGAMDEEVSILKAKLNNMETTIIAGCEFYQGELNGKQVILTKSGIGKVAAAVATTLLLERFNPGQVINTGSAGGY
DTTLNVGDIVISTEVRFHDVDLTAFGYEIGQMAQLPAAFPADKNLIFAAQKAAETITHLKTIQGLICTGDIFMADPTKAE
IARHNFPTMAACEMEAAAIAQVCYQFKVPFVIIRSLSDIAGKKSELSFEQYLPIAAKNASILVEEIINNLN
>Mature_231_residues
MKIGIIGAMDEEVSILKAKLNNMETTIIAGCEFYQGELNGKQVILTKSGIGKVAAAVATTLLLERFNPGQVINTGSAGGY
DTTLNVGDIVISTEVRFHDVDLTAFGYEIGQMAQLPAAFPADKNLIFAAQKAAETITHLKTIQGLICTGDIFMADPTKAE
IARHNFPTMAACEMEAAAIAQVCYQFKVPFVIIRSLSDIAGKKSELSFEQYLPIAAKNASILVEEIINNLN

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily

Homologues:

Organism=Escherichia coli, GI1786354, Length=230, Percent_Identity=53.9130434782609, Blast_Score=230, Evalue=6e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNN_PSYIN (A1STE7)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942361.1
- ProteinModelPortal:   A1STE7
- SMR:   A1STE7
- STRING:   A1STE7
- GeneID:   4623575
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0920
- eggNOG:   COG0775
- HOGENOM:   HBG367723
- OMA:   AMEQEVT
- PhylomeDB:   A1STE7
- BioCyc:   PING357804:PING_0920-MONOMER
- HAMAP:   MF_01684
- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR01704

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =3.2.2.9

Molecular weight: Translated: 24818; Mature: 24818

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: ACT_SITE 12-12 BINDING 78-78 BINDING 198-198

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGIIGAMDEEVSILKAKLNNMETTIIAGCEFYQGELNGKQVILTKSGIGKVAAAVATT
CEEEEEECCCHHHHHHHHHHCCCCEEEEECCEEEECCCCCCEEEEECCCCHHHHHHHHHH
LLLERFNPGQVINTGSAGGYDTTLNVGDIVISTEVRFHDVDLTAFGYEIGQMAQLPAAFP
HHHHCCCCCCEEECCCCCCCCCEEECCEEEEEEEEEEEEEEEEECCCCHHHHHHCCCCCC
ADKNLIFAAQKAAETITHLKTIQGLICTGDIFMADPTKAEIARHNFPTMAACEMEAAAIA
CCCCEEEEHHHHHHHHHHHHHHCCEEEECCEEEECCCHHHHHHCCCCCHHHHHHHHHHHH
QVCYQFKVPFVIIRSLSDIAGKKSELSFEQYLPIAAKNASILVEEIINNLN
HHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHCCEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKIGIIGAMDEEVSILKAKLNNMETTIIAGCEFYQGELNGKQVILTKSGIGKVAAAVATT
CEEEEEECCCHHHHHHHHHHCCCCEEEEECCEEEECCCCCCEEEEECCCCHHHHHHHHHH
LLLERFNPGQVINTGSAGGYDTTLNVGDIVISTEVRFHDVDLTAFGYEIGQMAQLPAAFP
HHHHCCCCCCEEECCCCCCCCCEEECCEEEEEEEEEEEEEEEEECCCCHHHHHHCCCCCC
ADKNLIFAAQKAAETITHLKTIQGLICTGDIFMADPTKAEIARHNFPTMAACEMEAAAIA
CCCCEEEEHHHHHHHHHHHHHHCCEEEECCEEEECCCHHHHHHCCCCCHHHHHHHHHHHH
QVCYQFKVPFVIIRSLSDIAGKKSELSFEQYLPIAAKNASILVEEIINNLN
HHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHCCEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA