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The map label for this gene is wecB [H]

Identifier: 119944554

GI number: 119944554

Start: 990816

End: 991943

Strand: Direct

Name: wecB [H]

Synonym: Ping_0791

Alternate gene names: 119944554

Gene position: 990816-991943 (Clockwise)

Preceding gene: 119944553

Following gene: 119944555

Centisome position: 21.73

GC content: 35.11

Gene sequence:

>1128_bases
ATGCAAAAATTAAAAGTAGCCACTATTGTTGGTACTCGCCCAGAGATTATCCGTTTATCCAGAACAATCACCAAATTAGA
TAAATATTGTGATCACACCTTAATTCATACAGGTCAGAATTATGACTATGAGCTAAACCAGATTTTTTTTGATGATTTAG
GTATCCGTGCGCCAGATGTTTTTTTAGAATGCGCGGGTGCAACCGCAGCAGATACGATGGCACAGGTTATCAGAAAATCA
GATAAAGTTTTTGAAGATATCCTGCCGGATGCATTACTTATTCTAGGTGACACAAATAGTGCACTTTCTGCTATTTCTGC
AAAACGTAGAAAAATTCCAATTTTTCATATGGAAGCAGGTAATCGTTGTTTTGATATGCGAGTGCCGGAAGAGATAAATC
GTAAAATAGTTGACCATATTTCTGATGTTAATATGCCCTACAGTGATATTGCGCGTGAATACCTATTACGCGAGGGATTA
AAGCCTGAGTTTATTATTAAAACAGGCAGTCCTATGGCTGAAGTATTATCATTTTACAAAGATAGTATTGATTCATCTGA
TGTTATTTCTCGTTTAGAAATTGAATCTGGTAAGTACTTTGTCGTGAGTGTTCACCGAGAAGAAAATGTTGACTCAGAGT
CCAATATTCACAAATATGTTAACGTGTTAAATACAATTGCAGATAAGTTTGGTTTGCCAATTATTGTTTCAACACACCCG
AGGACTCGTAAGAAAATTGAAGCATTAAATCTTCATTTTTCACCATTAGTTCAACTGTTAAAACCATTAGGATTTTCTGA
TTATGTGAAGCTTCAATGTGATTCTAAATTGGTTTTAAGTGACAGCGGGACTATCACTGAAGAATCTTCAATTATGAATT
TTTCAGCGTTAAATATTCGCGAAGCTCAAGAAAGACCAGAAGGTTTTGAAGAAGGGGCGGTTATGTTTACCGGTATGGAA
ATTGATAGGATATTGCAAGCAATTGACATATTGGAAGATCAAAGTGATGGTGAAAAACGAACACTAAATATAGTTGCTGA
TTACGTCGCACCAAATGTGTCAGATAAAGTGGTGCGTATTATTACTAGTTATACGGACTATGTTAATAAATTTGTTTGGA
AAAAATAA

Upstream 100 bases:

>100_bases
CGAAAAAATTACGCGATGCATTAAGCTTAGAAATCCCTTCTTGGAAGTCGCTTATTTCTGAAATGCATAATGACTATGAA
AATCGATATGAGAAATACAG

Downstream 100 bases:

>100_bases
TTAACGTCAATTAAAGTAGATGAAATTATTTTGTTTCATCTACTTTCTCCTCCTTATTGGAAATTATTAAATGCGCTTAG
CTTTATTGATTGATGATTAC

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MQKLKVATIVGTRPEIIRLSRTITKLDKYCDHTLIHTGQNYDYELNQIFFDDLGIRAPDVFLECAGATAADTMAQVIRKS
DKVFEDILPDALLILGDTNSALSAISAKRRKIPIFHMEAGNRCFDMRVPEEINRKIVDHISDVNMPYSDIAREYLLREGL
KPEFIIKTGSPMAEVLSFYKDSIDSSDVISRLEIESGKYFVVSVHREENVDSESNIHKYVNVLNTIADKFGLPIIVSTHP
RTRKKIEALNLHFSPLVQLLKPLGFSDYVKLQCDSKLVLSDSGTITEESSIMNFSALNIREAQERPEGFEEGAVMFTGME
IDRILQAIDILEDQSDGEKRTLNIVADYVAPNVSDKVVRIITSYTDYVNKFVWKK

Sequences:

>Translated_375_residues
MQKLKVATIVGTRPEIIRLSRTITKLDKYCDHTLIHTGQNYDYELNQIFFDDLGIRAPDVFLECAGATAADTMAQVIRKS
DKVFEDILPDALLILGDTNSALSAISAKRRKIPIFHMEAGNRCFDMRVPEEINRKIVDHISDVNMPYSDIAREYLLREGL
KPEFIIKTGSPMAEVLSFYKDSIDSSDVISRLEIESGKYFVVSVHREENVDSESNIHKYVNVLNTIADKFGLPIIVSTHP
RTRKKIEALNLHFSPLVQLLKPLGFSDYVKLQCDSKLVLSDSGTITEESSIMNFSALNIREAQERPEGFEEGAVMFTGME
IDRILQAIDILEDQSDGEKRTLNIVADYVAPNVSDKVVRIITSYTDYVNKFVWKK
>Mature_375_residues
MQKLKVATIVGTRPEIIRLSRTITKLDKYCDHTLIHTGQNYDYELNQIFFDDLGIRAPDVFLECAGATAADTMAQVIRKS
DKVFEDILPDALLILGDTNSALSAISAKRRKIPIFHMEAGNRCFDMRVPEEINRKIVDHISDVNMPYSDIAREYLLREGL
KPEFIIKTGSPMAEVLSFYKDSIDSSDVISRLEIESGKYFVVSVHREENVDSESNIHKYVNVLNTIADKFGLPIIVSTHP
RTRKKIEALNLHFSPLVQLLKPLGFSDYVKLQCDSKLVLSDSGTITEESSIMNFSALNIREAQERPEGFEEGAVMFTGME
IDRILQAIDILEDQSDGEKRTLNIVADYVAPNVSDKVVRIITSYTDYVNKFVWKK

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=358, Percent_Identity=27.0949720670391, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 42476; Mature: 42476

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLKVATIVGTRPEIIRLSRTITKLDKYCDHTLIHTGQNYDYELNQIFFDDLGIRAPDV
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEHHHEEHHHCCCCCCHH
FLECAGATAADTMAQVIRKSDKVFEDILPDALLILGDTNSALSAISAKRRKIPIFHMEAG
HHEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCEEEECCC
NRCFDMRVPEEINRKIVDHISDVNMPYSDIAREYLLREGLKPEFIIKTGSPMAEVLSFYK
CEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHH
DSIDSSDVISRLEIESGKYFVVSVHREENVDSESNIHKYVNVLNTIADKFGLPIIVSTHP
HCCCHHHHHHHHEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCC
RTRKKIEALNLHFSPLVQLLKPLGFSDYVKLQCDSKLVLSDSGTITEESSIMNFSALNIR
CHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCCCCCCCEEECCCHH
EAQERPEGFEEGAVMFTGMEIDRILQAIDILEDQSDGEKRTLNIVADYVAPNVSDKVVRI
HHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
ITSYTDYVNKFVWKK
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MQKLKVATIVGTRPEIIRLSRTITKLDKYCDHTLIHTGQNYDYELNQIFFDDLGIRAPDV
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEHHHEEHHHCCCCCCHH
FLECAGATAADTMAQVIRKSDKVFEDILPDALLILGDTNSALSAISAKRRKIPIFHMEAG
HHEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCEEEECCC
NRCFDMRVPEEINRKIVDHISDVNMPYSDIAREYLLREGLKPEFIIKTGSPMAEVLSFYK
CEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHH
DSIDSSDVISRLEIESGKYFVVSVHREENVDSESNIHKYVNVLNTIADKFGLPIIVSTHP
HCCCHHHHHHHHEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCC
RTRKKIEALNLHFSPLVQLLKPLGFSDYVKLQCDSKLVLSDSGTITEESSIMNFSALNIR
CHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCCCCCCCEEECCCHH
EAQERPEGFEEGAVMFTGMEIDRILQAIDILEDQSDGEKRTLNIVADYVAPNVSDKVVRI
HHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
ITSYTDYVNKFVWKK
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]