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The map label for this gene is ruvA

Identifier: 119944489

GI number: 119944489

Start: 911744

End: 912367

Strand: Direct

Name: ruvA

Synonym: Ping_0718

Alternate gene names: 119944489

Gene position: 911744-912367 (Clockwise)

Preceding gene: 119944488

Following gene: 119944490

Centisome position: 20.0

GC content: 42.63

Gene sequence:

>624_bases
ATGATTGGACGATTACGTGGTGTTTTATTAGAAAAGCAACCTCCAGAAGTGTTAATAGAAGTGTCAGGTATAGGCTACGA
AGTACAATTGCCGATGAGCTCTTTTTATGCTTTACCCGATGCAGGGCAAGAAGCCATTATTTATACGCATTTTGTGGTGC
GTGAAGATGCCCAGCTATTATACGGTTTTGCTGATAAACATGAACGTGCGATGTTTCGTGAATTAATAAAAGTGAATGGG
GTGGGTCCAAAGTTAGCACTGGCTATTTTGTCGGGCATGTCAGCAAATCAATTCGTGCAGTGTATTCATAATGATGCCGT
CACTACTTTAGTTAAATTGCCGGGGGTGGGTAAAAAAACCGCGGAGCGTTTAGTGGTTGAAATGAAAGACCGACTCAAAA
ACTGGACGGGTGCCGATTTATTAACACCGGCATCAGACAAAATGGTCTTTGAAAACGAATTTACCAATAGCGCTGCGAGC
GGTAATGCCAAAGATGAAGCTATCAGTGCGCTGGTAAGTTTAGGGTACAAGCCAGTTTTGGCAGAAAAAGCGATCCAGCA
AGTTTATGTGGAAGGCATGGATTGTGAGGCTTTGATCCGCAGTTCATTAAAAAGTATGCTCTAA

Upstream 100 bases:

>100_bases
TAAGTCTGGTTTATCAGAGTAGTTACTAAAAAATAATACTGGATATTTACTCAGTTGTTTTTTATGCTTGTCGCATTATA
TTATTAGCTAGGATGTTAGA

Downstream 100 bases:

>100_bases
ACGATAATCATAAGAAAGGTCGGGTAAAAAATGATAGATGAAGATCGTCTGATTTCAGGCACACAAAAGATTGATGAAAA
TTTTATTGATCGGGCTATCC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MIGRLRGVLLEKQPPEVLIEVSGIGYEVQLPMSSFYALPDAGQEAIIYTHFVVREDAQLLYGFADKHERAMFRELIKVNG
VGPKLALAILSGMSANQFVQCIHNDAVTTLVKLPGVGKKTAERLVVEMKDRLKNWTGADLLTPASDKMVFENEFTNSAAS
GNAKDEAISALVSLGYKPVLAEKAIQQVYVEGMDCEALIRSSLKSML

Sequences:

>Translated_207_residues
MIGRLRGVLLEKQPPEVLIEVSGIGYEVQLPMSSFYALPDAGQEAIIYTHFVVREDAQLLYGFADKHERAMFRELIKVNG
VGPKLALAILSGMSANQFVQCIHNDAVTTLVKLPGVGKKTAERLVVEMKDRLKNWTGADLLTPASDKMVFENEFTNSAAS
GNAKDEAISALVSLGYKPVLAEKAIQQVYVEGMDCEALIRSSLKSML
>Mature_207_residues
MIGRLRGVLLEKQPPEVLIEVSGIGYEVQLPMSSFYALPDAGQEAIIYTHFVVREDAQLLYGFADKHERAMFRELIKVNG
VGPKLALAILSGMSANQFVQCIHNDAVTTLVKLPGVGKKTAERLVVEMKDRLKNWTGADLLTPASDKMVFENEFTNSAAS
GNAKDEAISALVSLGYKPVLAEKAIQQVYVEGMDCEALIRSSLKSML

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=207, Percent_Identity=60.8695652173913, Blast_Score=258, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_PSYIN (A1SSV5)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942169.1
- ProteinModelPortal:   A1SSV5
- SMR:   A1SSV5
- STRING:   A1SSV5
- GeneID:   4625065
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0718
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   YKTAMSI
- PhylomeDB:   A1SSV5
- BioCyc:   PING357804:PING_0718-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 22660; Mature: 22660

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRLRGVLLEKQPPEVLIEVSGIGYEVQLPMSSFYALPDAGQEAIIYTHFVVREDAQLL
CCCCHHHHHCCCCCCCEEEEECCCCEEEEECHHHHCCCCCCCCCEEEEEEHHHHCCHHHH
YGFADKHERAMFRELIKVNGVGPKLALAILSGMSANQFVQCIHNDAVTTLVKLPGVGKKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLVVEMKDRLKNWTGADLLTPASDKMVFENEFTNSAASGNAKDEAISALVSLGYKPVL
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHH
AEKAIQQVYVEGMDCEALIRSSLKSML
HHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIGRLRGVLLEKQPPEVLIEVSGIGYEVQLPMSSFYALPDAGQEAIIYTHFVVREDAQLL
CCCCHHHHHCCCCCCCEEEEECCCCEEEEECHHHHCCCCCCCCCEEEEEEHHHHCCHHHH
YGFADKHERAMFRELIKVNGVGPKLALAILSGMSANQFVQCIHNDAVTTLVKLPGVGKKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLVVEMKDRLKNWTGADLLTPASDKMVFENEFTNSAASGNAKDEAISALVSLGYKPVL
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHH
AEKAIQQVYVEGMDCEALIRSSLKSML
HHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA