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The map label for this gene is dctB [H]

Identifier: 119944485

GI number: 119944485

Start: 906590

End: 908374

Strand: Reverse

Name: dctB [H]

Synonym: Ping_0714

Alternate gene names: 119944485

Gene position: 908374-906590 (Counterclockwise)

Preceding gene: 119944503

Following gene: 119944484

Centisome position: 19.92

GC content: 39.05

Gene sequence:

>1785_bases
ATGAGTCATAGTCATACCCAACGAATAACACTTGTACTTATTTTTTTCTATTTTCTAACCCTTATTCTGTCTGTTAATTG
GTTATGGAAATTTAGTTATGAACGTCTTATCACGACCAATCAGGAACAACTTGAGCGCTTTAGCCGTCACCTTGAAAGTC
AACTCGAACGCTTTGTTTATATTCCACAACTGTTATCTCGACAAGGGATATTGATTGACACATTAAATTCAGTCAATAAC
CCAGCTCAACGTGATATCACTAACCGCCACCTAGCGTCTATTAATGAAATTATTGGCGCATCGGACACTTACCTTCTCGA
TGCTAAGGGAACAACTATTGCGGCCAGTAATTGGTCAACGAGCACCTCTTTTGTTGGCAAAAATTTCGCTTTCCGCCCCT
ACTTTCAACAGGCGATAAATAATCAGCGGGGACATTATTTTGCGCTGGGTTCCACTTCTGGTCAGCGCGGTTATTATTTT
TCCTATCCCGTTAAATATGCCGCAGGAGTGTTAGGTGTGGTGGTCATTAAAATGGATCTTTCTTCAATAGAAAAAAATTG
GTCGGGAAAAGATCAGCATTTTCTGGTTACTGATAAAAATCATATTGTCTTTATTTCCAGCGAAAAATCTTGGTTATTCC
ACAGTATGGCCCCGCTTTCAACTCAATTAAAAAATCAGATTTTAAATAGTCGCCGATACCTTTCTCGAGAAATCAAAACA
TTATCCTTTTCAGGTGAGTTAGATAAGAGCCCTGCGGCGCTCAGTTTAAATACTAATAAACGATTAGGGAAAAATTATTT
ATCACTCACCAAAACGTTAAACAATGCGGATTGGCAGGTGCGGGTGCTTGTCCCGACAACATCCTTATTAATTAATGTCA
GCATACTTATTGTGTTTCTTTCCTTGTTTTATTTATCCGTCTATCTTATTTACATTTTGATAAGTCAAAAACAAAATAGA
CGCCATGAACAAACGCGATTACAAGATAACGCTAAGCAACAACTTGAATTTCAGGTGATGCGCCGCACCTCTGCATTACA
TGCGGAAATAGATGAAAGACGCAAAGCTGAACGGGCGCTGCGGGAGACTCAAAAAGAGTTGATCCAGTCTGCCAAATTAG
CCGTGTTAGGGCAACTTTCAGCCAGCATTAGTCATGAGTTGAATAACCCTCTGGCGGCCATTCGCAGTTATGCTGAAAAT
GCCATTATATTTCTTGAGCGTGATAAAATAGATAAAGTTTCCAATAACTTAATACGCATTACCTACCTTACCGACCGGAT
GGCAAAAATTAGTTCTCAGCTCAAAGCTTTTGCACGAAAATCAAACGGCGAGCTTTCTATTATCTCTTTACAGCCGGTGT
TAATGGCATCCTACGAATTGGTTAAACCCCAACTTAAGGCAAGCCGAGTATTATTACATATGAACCTGCCCGATAAACCG
GTTCAGGTAAAAGCTGAGCCTATTCAGTTAGAGCAAATAGTGGTTAATTTACTTTCCAATGCCATTCAGGCAATGGAAGA
ATGTAAAGAAAAACAGATTGAAATAATATTATCAGTGAATGGTCAACAGGCACAGATTGAAGTGATAGACACCGGTATAG
GTATTAATGAAAGTGATTTAGCAAAATTATTCGAACCTTTCTTTACCACTAAAGAAATGGGGCTTGGTTTAGGTCTGTCA
ATTTCCCAGCAGATCATAAAAAATATGCACGGTAAAATTTGGGCGAAAAACAGACAAGATCAGGGTGCCAAATTTTGTGT
TAGCCTGCCATTACAGAATGAATGA

Upstream 100 bases:

>100_bases
GTCACTTGGCAAATGAATAAAAGGCTAATAGTAAAAAATCAGGTAATCTATACCCTATATCCAGAAATTTAGGAGTTAAC
AGCAATGGCACCCACCCATA

Downstream 100 bases:

>100_bases
AGGAAGAGTAGAATTATGAATCCGGTTTTTTTTATTGATGATGAATATGATTTACGTAGCGCAAGTGAACAAACTTTTGA
ATTGGCAGAGATTGATGCGC

Product: C4-dicarboxylate transport sensor protein ATPase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MSHSHTQRITLVLIFFYFLTLILSVNWLWKFSYERLITTNQEQLERFSRHLESQLERFVYIPQLLSRQGILIDTLNSVNN
PAQRDITNRHLASINEIIGASDTYLLDAKGTTIAASNWSTSTSFVGKNFAFRPYFQQAINNQRGHYFALGSTSGQRGYYF
SYPVKYAAGVLGVVVIKMDLSSIEKNWSGKDQHFLVTDKNHIVFISSEKSWLFHSMAPLSTQLKNQILNSRRYLSREIKT
LSFSGELDKSPAALSLNTNKRLGKNYLSLTKTLNNADWQVRVLVPTTSLLINVSILIVFLSLFYLSVYLIYILISQKQNR
RHEQTRLQDNAKQQLEFQVMRRTSALHAEIDERRKAERALRETQKELIQSAKLAVLGQLSASISHELNNPLAAIRSYAEN
AIIFLERDKIDKVSNNLIRITYLTDRMAKISSQLKAFARKSNGELSIISLQPVLMASYELVKPQLKASRVLLHMNLPDKP
VQVKAEPIQLEQIVVNLLSNAIQAMEECKEKQIEIILSVNGQQAQIEVIDTGIGINESDLAKLFEPFFTTKEMGLGLGLS
ISQQIIKNMHGKIWAKNRQDQGAKFCVSLPLQNE

Sequences:

>Translated_594_residues
MSHSHTQRITLVLIFFYFLTLILSVNWLWKFSYERLITTNQEQLERFSRHLESQLERFVYIPQLLSRQGILIDTLNSVNN
PAQRDITNRHLASINEIIGASDTYLLDAKGTTIAASNWSTSTSFVGKNFAFRPYFQQAINNQRGHYFALGSTSGQRGYYF
SYPVKYAAGVLGVVVIKMDLSSIEKNWSGKDQHFLVTDKNHIVFISSEKSWLFHSMAPLSTQLKNQILNSRRYLSREIKT
LSFSGELDKSPAALSLNTNKRLGKNYLSLTKTLNNADWQVRVLVPTTSLLINVSILIVFLSLFYLSVYLIYILISQKQNR
RHEQTRLQDNAKQQLEFQVMRRTSALHAEIDERRKAERALRETQKELIQSAKLAVLGQLSASISHELNNPLAAIRSYAEN
AIIFLERDKIDKVSNNLIRITYLTDRMAKISSQLKAFARKSNGELSIISLQPVLMASYELVKPQLKASRVLLHMNLPDKP
VQVKAEPIQLEQIVVNLLSNAIQAMEECKEKQIEIILSVNGQQAQIEVIDTGIGINESDLAKLFEPFFTTKEMGLGLGLS
ISQQIIKNMHGKIWAKNRQDQGAKFCVSLPLQNE
>Mature_593_residues
SHSHTQRITLVLIFFYFLTLILSVNWLWKFSYERLITTNQEQLERFSRHLESQLERFVYIPQLLSRQGILIDTLNSVNNP
AQRDITNRHLASINEIIGASDTYLLDAKGTTIAASNWSTSTSFVGKNFAFRPYFQQAINNQRGHYFALGSTSGQRGYYFS
YPVKYAAGVLGVVVIKMDLSSIEKNWSGKDQHFLVTDKNHIVFISSEKSWLFHSMAPLSTQLKNQILNSRRYLSREIKTL
SFSGELDKSPAALSLNTNKRLGKNYLSLTKTLNNADWQVRVLVPTTSLLINVSILIVFLSLFYLSVYLIYILISQKQNRR
HEQTRLQDNAKQQLEFQVMRRTSALHAEIDERRKAERALRETQKELIQSAKLAVLGQLSASISHELNNPLAAIRSYAENA
IIFLERDKIDKVSNNLIRITYLTDRMAKISSQLKAFARKSNGELSIISLQPVLMASYELVKPQLKASRVLLHMNLPDKPV
QVKAEPIQLEQIVVNLLSNAIQAMEECKEKQIEIILSVNGQQAQIEVIDTGIGINESDLAKLFEPFFTTKEMGLGLGLSI
SQQIIKNMHGKIWAKNRQDQGAKFCVSLPLQNE

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=234, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=29.7071129707113, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI87081816, Length=270, Percent_Identity=28.5185185185185, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693157, Length=261, Percent_Identity=27.9693486590038, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082128, Length=221, Percent_Identity=28.9592760180996, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789149, Length=445, Percent_Identity=24.7191011235955, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1790861, Length=208, Percent_Identity=29.8076923076923, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786912, Length=250, Percent_Identity=27.2, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=234, Percent_Identity=25.6410256410256, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788393, Length=224, Percent_Identity=25.8928571428571, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790300, Length=252, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67669; Mature: 67538

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSHTQRITLVLIFFYFLTLILSVNWLWKFSYERLITTNQEQLERFSRHLESQLERFVY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IPQLLSRQGILIDTLNSVNNPAQRDITNRHLASINEIIGASDTYLLDAKGTTIAASNWST
HHHHHCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCC
STSFVGKNFAFRPYFQQAINNQRGHYFALGSTSGQRGYYFSYPVKYAAGVLGVVVIKMDL
CCHHCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCEEEECCHHHHHHHHHHHHEEEEH
SSIEKNWSGKDQHFLVTDKNHIVFISSEKSWLFHSMAPLSTQLKNQILNSRRYLSREIKT
HHHHCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHE
LSFSGELDKSPAALSLNTNKRLGKNYLSLTKTLNNADWQVRVLVPTTSLLINVSILIVFL
EEECCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHH
SLFYLSVYLIYILISQKQNRRHEQTRLQDNAKQQLEFQVMRRTSALHAEIDERRKAERAL
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RETQKELIQSAKLAVLGQLSASISHELNNPLAAIRSYAENAIIFLERDKIDKVSNNLIRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCHHHHCCCEEEE
TYLTDRMAKISSQLKAFARKSNGELSIISLQPVLMASYELVKPQLKASRVLLHMNLPDKP
EEEHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHCCHHCCCEEEEEECCCCCC
VQVKAEPIQLEQIVVNLLSNAIQAMEECKEKQIEIILSVNGQQAQIEVIDTGIGINESDL
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEEEECCCCCCHHHH
AKLFEPFFTTKEMGLGLGLSISQQIIKNMHGKIWAKNRQDQGAKFCVSLPLQNE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEECCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
SHSHTQRITLVLIFFYFLTLILSVNWLWKFSYERLITTNQEQLERFSRHLESQLERFVY
CCCHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IPQLLSRQGILIDTLNSVNNPAQRDITNRHLASINEIIGASDTYLLDAKGTTIAASNWST
HHHHHCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCC
STSFVGKNFAFRPYFQQAINNQRGHYFALGSTSGQRGYYFSYPVKYAAGVLGVVVIKMDL
CCHHCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCEEEECCHHHHHHHHHHHHEEEEH
SSIEKNWSGKDQHFLVTDKNHIVFISSEKSWLFHSMAPLSTQLKNQILNSRRYLSREIKT
HHHHCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHE
LSFSGELDKSPAALSLNTNKRLGKNYLSLTKTLNNADWQVRVLVPTTSLLINVSILIVFL
EEECCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHH
SLFYLSVYLIYILISQKQNRRHEQTRLQDNAKQQLEFQVMRRTSALHAEIDERRKAERAL
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RETQKELIQSAKLAVLGQLSASISHELNNPLAAIRSYAENAIIFLERDKIDKVSNNLIRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCHHHHCCCEEEE
TYLTDRMAKISSQLKAFARKSNGELSIISLQPVLMASYELVKPQLKASRVLLHMNLPDKP
EEEHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHCCHHCCCEEEEEECCCCCC
VQVKAEPIQLEQIVVNLLSNAIQAMEECKEKQIEIILSVNGQQAQIEVIDTGIGINESDL
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEEEECCCCCCHHHH
AKLFEPFFTTKEMGLGLGLSISQQIIKNMHGKIWAKNRQDQGAKFCVSLPLQNE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEECCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]