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The map label for this gene is mer [H]

Identifier: 119867205

GI number: 119867205

Start: 1240350

End: 1241399

Strand: Reverse

Name: mer [H]

Synonym: Mkms_1154

Alternate gene names: 119867205

Gene position: 1241399-1240350 (Counterclockwise)

Preceding gene: 119867206

Following gene: 119867193

Centisome position: 21.64

GC content: 66.38

Gene sequence:

>1050_bases
ATGGCTTCTCTGCGCACTGGCATCTTCTTGAGTTATGCGGGCGGTTTCCGTGAGGCCGTCGAGGACGTGGTCGAACTCGA
GAAGACCGGGGTCGACATCGCCCTGGTCGCGGAGGCCTACTCGTTCGACGCGATCAGCCAGTTGGGTTACCTGGCCGCCA
AGACCTCGCGCATCGAACTCGGTACCGGGGTGGTGCCGATCTACGTGCGGACGCCGTCGCTGCTGGCGATGACCGCGGCG
GGCCTCGACTACGTCTCCGACGGCCGGTTCCGGTTGGGCATCGGCACGTCCGGCCCGCAGGTGATGGAGGGTTTTCACGG
CGTCCCGTTCGACGCGCCACTGGGCCGCACGCGCGAGGTGGTGGAGATCTGCCGGAAGGTGTGGCGCCGCGAGAACGTCG
AATTCGACGGCCGCTACTACCAGATTCCGCTGCCTGCCGACCGTGGCAGCGGCCTGGGTAAACCGCTGCATCTGATCAAT
CATCCGGTGCGCGAACGCATTCCGATCACCATCGCCGCCCTCGGACCCAAGAACGTCGAGCTGACCGCCGAGATCGCCGA
AGGTTGGCAGCCGGTGTTCTTCTACCCCGAGAAGGCGGATGCGGTGTGGGGTGACGCGCTACGCGCGGGCTACGCCAAAC
GCGACCCGGCGCTCGGACCGCTGGACGTGATGGTGAGCGCCGCGCTGGCGATCGGCGACGACGTCGAGGACCGGTTGCAG
TGGGTGAAACCGCAACTGGCGTTGTACATCGGCGGTATGGGCGCCCGGGGCAGGAACTTCTACCACAACCTCGCGACGCG
CTACGGTTTCGGCGAGGTGGCCGATCAGATCCAGGATCTGTACCTGTCGGGCAAGAAGGCCGAGGCAATCGCTGCGGTGC
CCGACGACCTCGTCCGCTCGGTCTCGCTGATCGGTTCGAAAGCTTTCGTCAAGGAGAGGTTGGCCGCCTTCGTCGAGGGC
GGTGCCACCACCCTGCTGCTGCAGCCGGTGACCGCCGACCGCCGCGAATCGGTGCGTTTCGTGGAGGACTTGCAGGCGCT
GCTCCCCTGA

Upstream 100 bases:

>100_bases
ACGATTCGGTCGATCTCGAGAACAAGGTCGTCGCCCTGCTGAAGCCGTAGTTTCCGGCCGCGGCTCGGGCCAACCAACCG
GTTGGGTGTATAAACCTTCC

Downstream 100 bases:

>100_bases
GTCGCGGAACTCACTCGCCAACCTGCGGAACCTCGTTCGCGGCGATCTCACACGGTGTCGCCGAGTCCGGCCCGGGTGGC
GGTGCAATCGGTTCGGCCAA

Product: luciferase family protein

Products: NA

Alternate protein names: Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase; Methylene-H(4)MPT reductase [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MASLRTGIFLSYAGGFREAVEDVVELEKTGVDIALVAEAYSFDAISQLGYLAAKTSRIELGTGVVPIYVRTPSLLAMTAA
GLDYVSDGRFRLGIGTSGPQVMEGFHGVPFDAPLGRTREVVEICRKVWRRENVEFDGRYYQIPLPADRGSGLGKPLHLIN
HPVRERIPITIAALGPKNVELTAEIAEGWQPVFFYPEKADAVWGDALRAGYAKRDPALGPLDVMVSAALAIGDDVEDRLQ
WVKPQLALYIGGMGARGRNFYHNLATRYGFGEVADQIQDLYLSGKKAEAIAAVPDDLVRSVSLIGSKAFVKERLAAFVEG
GATTLLLQPVTADRRESVRFVEDLQALLP

Sequences:

>Translated_349_residues
MASLRTGIFLSYAGGFREAVEDVVELEKTGVDIALVAEAYSFDAISQLGYLAAKTSRIELGTGVVPIYVRTPSLLAMTAA
GLDYVSDGRFRLGIGTSGPQVMEGFHGVPFDAPLGRTREVVEICRKVWRRENVEFDGRYYQIPLPADRGSGLGKPLHLIN
HPVRERIPITIAALGPKNVELTAEIAEGWQPVFFYPEKADAVWGDALRAGYAKRDPALGPLDVMVSAALAIGDDVEDRLQ
WVKPQLALYIGGMGARGRNFYHNLATRYGFGEVADQIQDLYLSGKKAEAIAAVPDDLVRSVSLIGSKAFVKERLAAFVEG
GATTLLLQPVTADRRESVRFVEDLQALLP
>Mature_348_residues
ASLRTGIFLSYAGGFREAVEDVVELEKTGVDIALVAEAYSFDAISQLGYLAAKTSRIELGTGVVPIYVRTPSLLAMTAAG
LDYVSDGRFRLGIGTSGPQVMEGFHGVPFDAPLGRTREVVEICRKVWRRENVEFDGRYYQIPLPADRGSGLGKPLHLINH
PVRERIPITIAALGPKNVELTAEIAEGWQPVFFYPEKADAVWGDALRAGYAKRDPALGPLDVMVSAALAIGDDVEDRLQW
VKPQLALYIGGMGARGRNFYHNLATRYGFGEVADQIQDLYLSGKKAEAIAAVPDDLVRSVSLIGSKAFVKERLAAFVEGG
ATTLLLQPVTADRRESVRFVEDLQALLP

Specific function: Catalyzes the oxidation of methyl-H(4)MPT to methylene- H(4)MPT [H]

COG id: COG2141

COG function: function code C; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mer family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011251
- InterPro:   IPR016048
- InterPro:   IPR019946 [H]

Pfam domain/function: PF00296 Bac_luciferase [H]

EC number: =1.5.99.11 [H]

Molecular weight: Translated: 37964; Mature: 37833

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLRTGIFLSYAGGFREAVEDVVELEKTGVDIALVAEAYSFDAISQLGYLAAKTSRIEL
CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEECHHCHHHHHHHHHHHHCCCEEEE
GTGVVPIYVRTPSLLAMTAAGLDYVSDGRFRLGIGTSGPQVMEGFHGVPFDAPLGRTREV
CCCEEEEEEECCHHHHHHHHCCCEECCCCEEEEECCCCHHHHHCCCCCCCCCCCCCCHHH
VEICRKVWRRENVEFDGRYYQIPLPADRGSGLGKPLHLINHPVRERIPITIAALGPKNVE
HHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHCCCHHHCCCEEEEECCCCCEE
LTAEIAEGWQPVFFYPEKADAVWGDALRAGYAKRDPALGPLDVMVSAALAIGDDVEDRLQ
EEEEHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
WVKPQLALYIGGMGARGRNFYHNLATRYGFGEVADQIQDLYLSGKKAEAIAAVPDDLVRS
HHCCCEEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHH
VSLIGSKAFVKERLAAFVEGGATTLLLQPVTADRRESVRFVEDLQALLP
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASLRTGIFLSYAGGFREAVEDVVELEKTGVDIALVAEAYSFDAISQLGYLAAKTSRIEL
CCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEECHHCHHHHHHHHHHHHCCCEEEE
GTGVVPIYVRTPSLLAMTAAGLDYVSDGRFRLGIGTSGPQVMEGFHGVPFDAPLGRTREV
CCCEEEEEEECCHHHHHHHHCCCEECCCCEEEEECCCCHHHHHCCCCCCCCCCCCCCHHH
VEICRKVWRRENVEFDGRYYQIPLPADRGSGLGKPLHLINHPVRERIPITIAALGPKNVE
HHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHCCCHHHCCCEEEEECCCCCEE
LTAEIAEGWQPVFFYPEKADAVWGDALRAGYAKRDPALGPLDVMVSAALAIGDDVEDRLQ
EEEEHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
WVKPQLALYIGGMGARGRNFYHNLATRYGFGEVADQIQDLYLSGKKAEAIAAVPDDLVRS
HHCCCEEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHH
VSLIGSKAFVKERLAAFVEGGATTLLLQPVTADRRESVRFVEDLQALLP
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]