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The map label for this gene is 119855064

Identifier: 119855064

GI number: 119855064

Start: 187673

End: 188494

Strand: Direct

Name: 119855064

Synonym: Mkms_5675

Alternate gene names: NA

Gene position: 187673-188494 (Clockwise)

Preceding gene: 119855063

Following gene: 119855070

Centisome position: 62.13

GC content: 63.87

Gene sequence:

>822_bases
ATGACGATCGACCCGTTCAGCGCTGCAGATGAATTCGAGCATGCCGACGTCGACACTGTGGTCATCTTCGTCGACATCGC
GGGGTTCACGGCGTTCACCGAGGCCCACGGTGATCATCGTGCTGCCGAACTGGCGGACCGGTTCGCCACCATAGCCGCGA
GGGTCCTCGGGCCCGGCGACGAGATGATCAAGACCCTCGGCGATGCCGTGATGATCACCAGTTCGGACCCCGCCGCGGCG
TTGGCTTTCCTTCGGCGACTCCACGACGAAACCCGGCGTATCGACGGCTTTCCGTTGTTGCGCGCAGGCATCTGTGCCGG
GGCGGTGGTGAAGCGCCGCGGAGACGTCTTCGGGTCGACGGTCAACACCGCAGCCAGACTGGCCGCCGTCGCCCGGCCAG
GCCAAATCGTCGGCAACGCCGACGCCGCTTCCGCGCTTCGGGGAACGGATCTTCTCGCGACGACGTCGTTGGGCTCGCTT
CGGTTGCGGAATGTCGGTGCGCTGGTGGAAGCGTTCGCCCTCGACGTCGGAACCCGCCACCAGGAGCACGTCGATCCGAT
ATGTCGGATGCACGTCTCGACAGATGCACAATCGCTGACGATCACGCATGAGGAGGACACTTACCGGTTCTACTTCTGTT
CGACGGCCTGTCTACGCCAATTCGCAGACCGCGTTGGCGATATGAGCACATCATCTGGTGACGGGGATTCGGCGTCCATT
CAGTCGTTCTTGGGTGAGGTCGCGGTCCCTTTGGGCACGCTGAGGTCCCCGACGAGCGGGCGGGGGGCTGCACCGATGTC
GACTCGTTCAACCTCCTGCTAA

Upstream 100 bases:

>100_bases
CTACTCTTATCGTCGTCGCCAATGCGTTGCGCCTCCTCGGGATGCCGATGCAGTCGGTGACCCCAGCAGCGCCGCGCGTT
GAGCGTGCAGAAGAGACGCC

Downstream 100 bases:

>100_bases
GGGCCGAAGTTCACCACATGCTCCCGAATGGTGTTCGCCATCAATACTATTCGCGCGAGACGAGACCGGTCGGGCCGTCG
CAAGTATCGGACGCCTTGCC

Product: putative adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase; Adenylyl cyclase [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MTIDPFSAADEFEHADVDTVVIFVDIAGFTAFTEAHGDHRAAELADRFATIAARVLGPGDEMIKTLGDAVMITSSDPAAA
LAFLRRLHDETRRIDGFPLLRAGICAGAVVKRRGDVFGSTVNTAARLAAVARPGQIVGNADAASALRGTDLLATTSLGSL
RLRNVGALVEAFALDVGTRHQEHVDPICRMHVSTDAQSLTITHEEDTYRFYFCSTACLRQFADRVGDMSTSSGDGDSASI
QSFLGEVAVPLGTLRSPTSGRGAAPMSTRSTSC

Sequences:

>Translated_273_residues
MTIDPFSAADEFEHADVDTVVIFVDIAGFTAFTEAHGDHRAAELADRFATIAARVLGPGDEMIKTLGDAVMITSSDPAAA
LAFLRRLHDETRRIDGFPLLRAGICAGAVVKRRGDVFGSTVNTAARLAAVARPGQIVGNADAASALRGTDLLATTSLGSL
RLRNVGALVEAFALDVGTRHQEHVDPICRMHVSTDAQSLTITHEEDTYRFYFCSTACLRQFADRVGDMSTSSGDGDSASI
QSFLGEVAVPLGTLRSPTSGRGAAPMSTRSTSC
>Mature_272_residues
TIDPFSAADEFEHADVDTVVIFVDIAGFTAFTEAHGDHRAAELADRFATIAARVLGPGDEMIKTLGDAVMITSSDPAAAL
AFLRRLHDETRRIDGFPLLRAGICAGAVVKRRGDVFGSTVNTAARLAAVARPGQIVGNADAASALRGTDLLATTSLGSLR
LRNVGALVEAFALDVGTRHQEHVDPICRMHVSTDAQSLTITHEEDTYRFYFCSTACLRQFADRVGDMSTSSGDGDSASIQ
SFLGEVAVPLGTLRSPTSGRGAAPMSTRSTSC

Specific function: Catalyzes the formation of the second messenger cAMP [H]

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 28819; Mature: 28687

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDPFSAADEFEHADVDTVVIFVDIAGFTAFTEAHGDHRAAELADRFATIAARVLGPGD
CCCCCCCCCCHHCCCCCCEEEEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCH
EMIKTLGDAVMITSSDPAAALAFLRRLHDETRRIDGFPLLRAGICAGAVVKRRGDVFGST
HHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCH
VNTAARLAAVARPGQIVGNADAASALRGTDLLATTSLGSLRLRNVGALVEAFALDVGTRH
HHHHHHHHHHCCCCCEECCCHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCC
QEHVDPICRMHVSTDAQSLTITHEEDTYRFYFCSTACLRQFADRVGDMSTSSGDGDSASI
HHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCHHHH
QSFLGEVAVPLGTLRSPTSGRGAAPMSTRSTSC
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TIDPFSAADEFEHADVDTVVIFVDIAGFTAFTEAHGDHRAAELADRFATIAARVLGPGD
CCCCCCCCCHHCCCCCCEEEEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCH
EMIKTLGDAVMITSSDPAAALAFLRRLHDETRRIDGFPLLRAGICAGAVVKRRGDVFGST
HHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCH
VNTAARLAAVARPGQIVGNADAASALRGTDLLATTSLGSLRLRNVGALVEAFALDVGTRH
HHHHHHHHHHCCCCCEECCCHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCC
QEHVDPICRMHVSTDAQSLTITHEEDTYRFYFCSTACLRQFADRVGDMSTSSGDGDSASI
HHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCHHHH
QSFLGEVAVPLGTLRSPTSGRGAAPMSTRSTSC
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]