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The map label for this gene is ctaD [H]

Identifier: 119855059

GI number: 119855059

Start: 178304

End: 180049

Strand: Direct

Name: ctaD [H]

Synonym: Mkms_5670

Alternate gene names: 119855059

Gene position: 178304-180049 (Clockwise)

Preceding gene: 119855054

Following gene: 119855060

Centisome position: 59.02

GC content: 62.89

Gene sequence:

>1746_bases
ATGGTCGCCGATGCGCCATCGGTCGGGGAACTTGAGGTACGCCGTCCTTTTCCGGCCCGGATGGGCCCCAAAGGCAACCT
GATCTACCGGTTGATCACGACCACCGATCACAAGTTGATCGGCATCATGTACTGCGTCGCCTGCTTCGCGTTCTTCCTCA
TCGGCGGCCTGATGGCGCTGTTCATCCGCACCGAGCTGGCCGTGCCCGGCCTGCAGTTCCTGTCCAATGAGCAGTACAAC
CAGCTGTTCACCATGCACGGCACGGTGATGTTGCTGTTCTACGCCACCCCGATCGTGTTCGGCTTCGCGAACCTGGTGCT
TCCGCTGCAGATCGGCGCGCCCGACGTGGCGTTCCCGCGGCTGAACGCGTTCTCGTTCTGGCTGTTCCTCTTCGGTGCAC
TGATCGCCACCGCGGGCTTCATCACCCCCGGTGGTGCTGCGGATTTCGGCTGGACCGCCTACACACCCTTGTCTAGTGCG
ATCAATTCACCAGGCGCCGGCGCCGACCTCTGGATTCTCGGCCTGATCGTCGGTGGGCTGGGCACGATTTTAGGCGCGGT
CAACATGATTACCACCGTGGTGTGTATGCGTGCGCCGGGCATGACGATGTTTCGGATGCCGATCTTCACCTGGAACATCC
TGGTGACGTCGATCCTGGTGCTGCTGGCGTTTCCGCTGCTGACCGCGGCATTGTTCGCGTTGGCCGCCGACCGTCACCTC
GGTGCCCACGTGTACGACCCGGCGAACGGAGGTGTGTTGCTGTGGCAGCACTTGTTCTGGTTCTTCGGCCATCCAGAGGT
GTACATCATTGCGCTGCCGTTCTTCGGCATCGTGTCGGAGATCTTCCCGGTGTTCTCCCGTAAGCCGATCTTCGGCTACA
CCACGCTGATCTACGCGACGCTGGGCATCGCGGCGCTGTCGGTGGCGGTGTGGGCGCACCACATGTACGCCACCGGTGCG
GTGCTGTTGCCGTTCTTCTCGTTCATGACGTTCCTGATCGCGGTCCCGACGGGCATCAAGTTCTTCAACTGGATAGGCAC
GATGTGGAAGGGCCAGTTGACGTTCGAGACGCCGATGCTGTTCTCCGTCGGCTTCATAGTGACGTTCCTGCTCGGTGGTC
TGTCCGGGGTGCTGCTGGCCAGCCCGCCGATCGACTTCCAGGTCACCGACAGCTACTTCGTCATCGCGCACTTCCACTAC
GTGCTGTTCGGCACCATCGTGTTCGCCACCTATGCGGGGATCTACTTCTGGTTCCCGAAGATGACGGGCCGGTTGCTCGA
CGAGCGGCTGGGCAAGCTGCACTTCTGGCTGACCTTCATCGGCTTCCACACCACGTTCCTGGTGCAGCACTGGCTCGGCA
ACGAGGGCATGCCGCGCCGCTACGCCGACTACCTGCCCAGCGACGGCTTCACCACGCTGAACATCGTGTCCACCATCGGT
GCATTCATCCTGGGCGCCTCGACGCTGCCGTTCCTGTGGAACATCTTCAAGAGCTGGCGCTACGGCGAGGTCGTCACCGT
CGACGATCCGTGGGGGTACGGAAACTCCCTGGAGTGGGCCACCAGTTGCCCGCCGCCGCGGCACAACTTCACCGAGCTGC
CCAGGATCCGTTCCGAGCGCCCCGCCTTCGAGCTGCACTACCCGCACATGGTCGAACGGATGCGCCGCGAAGCCCACGTC
GGCCGTGCCCACGGACCTGATGACGGAGACGTCACGCGCCTCGACGACGCTCAAGTGCGCACCTAA

Upstream 100 bases:

>100_bases
CAACTACGCAAGTTAGTACTAAGCTACGCAGTACGATAACCTACGTATCTAGTCAGTAGATAGTGGGAACGCGGTCCGAG
CCCGTGGCGGAAGGGTTTTA

Downstream 100 bases:

>100_bases
AACGGCTCCGCCATGATGCCGAAATGCGAAAGCGCCTGATGCGCGGTCACTGTCGAGGCGCCCGCATCCCGACGCAGATG
CGGCTGCTGTTGAGGCCTCG

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MVADAPSVGELEVRRPFPARMGPKGNLIYRLITTTDHKLIGIMYCVACFAFFLIGGLMALFIRTELAVPGLQFLSNEQYN
QLFTMHGTVMLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGALIATAGFITPGGAADFGWTAYTPLSSA
INSPGAGADLWILGLIVGGLGTILGAVNMITTVVCMRAPGMTMFRMPIFTWNILVTSILVLLAFPLLTAALFALAADRHL
GAHVYDPANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYATLGIAALSVAVWAHHMYATGA
VLLPFFSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPMLFSVGFIVTFLLGGLSGVLLASPPIDFQVTDSYFVIAHFHY
VLFGTIVFATYAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQHWLGNEGMPRRYADYLPSDGFTTLNIVSTIG
AFILGASTLPFLWNIFKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHMVERMRREAHV
GRAHGPDDGDVTRLDDAQVRT

Sequences:

>Translated_581_residues
MVADAPSVGELEVRRPFPARMGPKGNLIYRLITTTDHKLIGIMYCVACFAFFLIGGLMALFIRTELAVPGLQFLSNEQYN
QLFTMHGTVMLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGALIATAGFITPGGAADFGWTAYTPLSSA
INSPGAGADLWILGLIVGGLGTILGAVNMITTVVCMRAPGMTMFRMPIFTWNILVTSILVLLAFPLLTAALFALAADRHL
GAHVYDPANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYATLGIAALSVAVWAHHMYATGA
VLLPFFSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPMLFSVGFIVTFLLGGLSGVLLASPPIDFQVTDSYFVIAHFHY
VLFGTIVFATYAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQHWLGNEGMPRRYADYLPSDGFTTLNIVSTIG
AFILGASTLPFLWNIFKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHMVERMRREAHV
GRAHGPDDGDVTRLDDAQVRT
>Mature_581_residues
MVADAPSVGELEVRRPFPARMGPKGNLIYRLITTTDHKLIGIMYCVACFAFFLIGGLMALFIRTELAVPGLQFLSNEQYN
QLFTMHGTVMLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGALIATAGFITPGGAADFGWTAYTPLSSA
INSPGAGADLWILGLIVGGLGTILGAVNMITTVVCMRAPGMTMFRMPIFTWNILVTSILVLLAFPLLTAALFALAADRHL
GAHVYDPANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYATLGIAALSVAVWAHHMYATGA
VLLPFFSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPMLFSVGFIVTFLLGGLSGVLLASPPIDFQVTDSYFVIAHFHY
VLFGTIVFATYAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQHWLGNEGMPRRYADYLPSDGFTTLNIVSTIG
AFILGASTLPFLWNIFKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHMVERMRREAHV
GRAHGPDDGDVTRLDDAQVRT

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=517, Percent_Identity=42.9400386847195, Blast_Score=378, Evalue=1e-104,
Organism=Escherichia coli, GI1786634, Length=545, Percent_Identity=42.5688073394495, Blast_Score=418, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6226519, Length=538, Percent_Identity=37.7323420074349, Blast_Score=351, Evalue=2e-97,
Organism=Saccharomyces cerevisiae, GI6226524, Length=325, Percent_Identity=40.3076923076923, Blast_Score=234, Evalue=3e-62,
Organism=Saccharomyces cerevisiae, GI6226523, Length=251, Percent_Identity=36.6533864541833, Blast_Score=146, Evalue=8e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 64683; Mature: 64683

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVADAPSVGELEVRRPFPARMGPKGNLIYRLITTTDHKLIGIMYCVACFAFFLIGGLMAL
CCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
FIRTELAVPGLQFLSNEQYNQLFTMHGTVMLLFYATPIVFGFANLVLPLQIGAPDVAFPR
HHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCC
LNAFSFWLFLFGALIATAGFITPGGAADFGWTAYTPLSSAINSPGAGADLWILGLIVGGL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHH
GTILGAVNMITTVVCMRAPGMTMFRMPIFTWNILVTSILVLLAFPLLTAALFALAADRHL
HHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GAHVYDPANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYAT
CCEEECCCCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHH
LGIAALSVAVWAHHMYATGAVLLPFFSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCHHH
FSVGFIVTFLLGGLSGVLLASPPIDFQVTDSYFVIAHFHYVLFGTIVFATYAGIYFWFPK
HHHHHHHHHHHHHHCCCEEECCCCCEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
MTGRLLDERLGKLHFWLTFIGFHTTFLVQHWLGNEGMPRRYADYLPSDGFTTLNIVSTIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHH
AFILGASTLPFLWNIFKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSER
HHHHCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCC
PAFELHYPHMVERMRREAHVGRAHGPDDGDVTRLDDAQVRT
CCEEECCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCC
>Mature Secondary Structure
MVADAPSVGELEVRRPFPARMGPKGNLIYRLITTTDHKLIGIMYCVACFAFFLIGGLMAL
CCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
FIRTELAVPGLQFLSNEQYNQLFTMHGTVMLLFYATPIVFGFANLVLPLQIGAPDVAFPR
HHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCC
LNAFSFWLFLFGALIATAGFITPGGAADFGWTAYTPLSSAINSPGAGADLWILGLIVGGL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHH
GTILGAVNMITTVVCMRAPGMTMFRMPIFTWNILVTSILVLLAFPLLTAALFALAADRHL
HHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GAHVYDPANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYAT
CCEEECCCCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHH
LGIAALSVAVWAHHMYATGAVLLPFFSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCHHH
FSVGFIVTFLLGGLSGVLLASPPIDFQVTDSYFVIAHFHYVLFGTIVFATYAGIYFWFPK
HHHHHHHHHHHHHHCCCEEECCCCCEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
MTGRLLDERLGKLHFWLTFIGFHTTFLVQHWLGNEGMPRRYADYLPSDGFTTLNIVSTIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHH
AFILGASTLPFLWNIFKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSER
HHHHCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCC
PAFELHYPHMVERMRREAHVGRAHGPDDGDVTRLDDAQVRT
CCEEECCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA