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The map label for this gene is recG [H]

Identifier: 119776507

GI number: 119776507

Start: 4002900

End: 4004975

Strand: Direct

Name: recG [H]

Synonym: Sama_3375

Alternate gene names: 119776507

Gene position: 4002900-4004975 (Clockwise)

Preceding gene: 119776506

Following gene: 119776508

Centisome position: 92.96

GC content: 59.25

Gene sequence:

>2076_bases
TTGCAAAGACTGGATCTTGTTCCCGTAACCGAACTCAAGGGCGTGGCGGCCCGGGTCGCAGAAAAACTCAGTAAACTGGG
GGTGAATACCGTCCAGGATTTACTGTTTCATCTGCCGCTGCGTTACGAAGACAGAACCCGCATCTATGCCATTGATGAAC
TTATCCCAGGCACCACAGCCACCATCGAAGCCGAAGTCATTTCCAGCCAGATCGTCAATGGCCGCAAGCGCATGCTCACC
TGCAACGTGCGCGACGCCAGTGGTGGCCTGACCTTACGTTTTTTCAATTTTTCCATGGCGCAAAAGAATGGCTTGCAGCC
AGGCATGACTATCCGCGCCTTTGGGGAAATCCGTACCGGCAAGCATCAGCTGGAAATCATCCATCCGGAATACAAGCTCA
CGGCGGCCGGCGAATCACCTAGCCTGGCCGACACCTTGACGCCCATCTATCCCACTACCGAAGGCCTGAAGCAAGCCAGC
TGGATACGGCTTACAGCACAGGCGCTGGAGCAATTGGAAGAAGGAGGGCTTCCGGAGCTTCTGCCCGAGTCATTACAGCC
CAACCGTTTAAGCCTGGCCGATGCCGTGCGCACCCTGCACCGCCCTCCGGCGGATGCCGAACTGTGGCAGTTGGAGCAAG
GCCAGCACCCGGCGCAGCAGCGGCTGGTGCAGGAAGAGCTGCTGGCCCATAACTTAAGCATGTTAAAGCTTCGGGAGCGC
AGCAATCAGGATGCCGCTGAGCCCTTGGCTGCCACGGGTCAGCTTATCCCCCGTTTTCTTGAGAGCCTGCCATTTGCCCC
AACCAATGCCCAGTCACGGGTAGTTGCTGAGATCCATGCCGATATGACCAAAGCCACCCCCATGATGCGTCTGGTGCAGG
GTGACGTGGGCTCGGGCAAAACCCTGGTAGCGGCACTATCTGCGCTGGCGGCCATCGAAAATGGCTGTCAGGTCGCCTTG
ATGGCCCCCACCGAGCTTTTGGCCGAGCAGCATGCCGCCAACTTTGCCCGCTGGTTTGAGCCGCTGGGGCTGAAAGTTGG
CTGGCTTGCCGGCAAACTCAAAGGCAAGGCCCGCACTCAAACGCTGGAAGACATCGCCTCCGGCGCCGCCCAGATGATAG
TGGGCACTCACGCCATTTTTCAGGAACAGGTGAGCTTTTCCCGCCTCGCCCTTACCATCATCGACGAGCAGCACCGCTTT
GGCGTACACCAGCGTCTGGGACTGCGTGAAAAAGGCATTCAGCAGGGCTTTTTCCCTCATCAGCTGATCATGACCGCCAC
CCCCATCCCCCGCACATTGGCAATGACCGCCTATGCAGATCTCGACACCTCGATTATTGATGAGCTGCCGCCGGGGCGAA
CTCCCATCACCACGGTTGCCATTCCCGACACCCGCCGGCTGGATGTGATTGAGCGGGTGCGACAGGCCGCCTTACAGGAC
AAGCGTCAGGCCTATTGGGTGTGCACCCTGATTGAAGAGTCGGAAGTACTCGAATGTCAGGCCGCCGAAGACACCGCTGG
GGGTCTGAAAGAAGCCCTGCCAGAGCTTGGCATTGGGCTGGTACACGGCCGGATGAAGGGCGCCGAAAAGCAGGCCATCA
TGGCCGACTTCAAAGCAGGCAAGCTCGACTTACTGGTTGCCACCACGGTTATCGAAGTGGGTGTGGATGTGCCCAATGCA
AGTTTGATGATAATCGAAAACCCCGAACGGCTGGGGCTTGCCCAGTTGCATCAGCTGCGGGGGCGGGTTGGCCGCGGCGC
AGTGGCCAGCCACTGCGTACTGCTGTACAAGGCGCCGCTCAGCTTTACCGCTCAGGCGCGTCTTGGGGTGCTGCGGGAAA
GTAACGACGGCTTTGTGATTGCCCAGAAAGATCTGGAGCTGCGTGGCCCCGGCGAGGTGCTCGGTACGCGCCAGACGGGG
CTTGCGCAAATGAAGGTGGCCGATTTGGTACGGGATCAGGCGCTTATTCCCCACATCCAAAAACTGGCGCGGCATCTGAT
GACCCAGGCCCCCGACAATGTGGATGCCATAATTGAGCGTTGGCTTGGCGGCCGCGAGCAATACGTACAGGCCTAG

Upstream 100 bases:

>100_bases
ATAGGGCGAAACGGGGAAATGAAGCAGTTTGCGCTAAGTTGCTCCGAAAAAATTCTCTGTTAGTATATGTATAAATTCAC
AGTAATCCGGTGCCAAGGCA

Downstream 100 bases:

>100_bases
CCTGCATTAAATATTGTTTTTGTTCAGCCTTGGACTATGGACATCGACCGGCGAACTGGGACAATGGGTGTTTCACGGGT
CAGTCGCAACAAGGAACCAA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 691

Protein sequence:

>691_residues
MQRLDLVPVTELKGVAARVAEKLSKLGVNTVQDLLFHLPLRYEDRTRIYAIDELIPGTTATIEAEVISSQIVNGRKRMLT
CNVRDASGGLTLRFFNFSMAQKNGLQPGMTIRAFGEIRTGKHQLEIIHPEYKLTAAGESPSLADTLTPIYPTTEGLKQAS
WIRLTAQALEQLEEGGLPELLPESLQPNRLSLADAVRTLHRPPADAELWQLEQGQHPAQQRLVQEELLAHNLSMLKLRER
SNQDAAEPLAATGQLIPRFLESLPFAPTNAQSRVVAEIHADMTKATPMMRLVQGDVGSGKTLVAALSALAAIENGCQVAL
MAPTELLAEQHAANFARWFEPLGLKVGWLAGKLKGKARTQTLEDIASGAAQMIVGTHAIFQEQVSFSRLALTIIDEQHRF
GVHQRLGLREKGIQQGFFPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPITTVAIPDTRRLDVIERVRQAALQD
KRQAYWVCTLIEESEVLECQAAEDTAGGLKEALPELGIGLVHGRMKGAEKQAIMADFKAGKLDLLVATTVIEVGVDVPNA
SLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKAPLSFTAQARLGVLRESNDGFVIAQKDLELRGPGEVLGTRQTG
LAQMKVADLVRDQALIPHIQKLARHLMTQAPDNVDAIIERWLGGREQYVQA

Sequences:

>Translated_691_residues
MQRLDLVPVTELKGVAARVAEKLSKLGVNTVQDLLFHLPLRYEDRTRIYAIDELIPGTTATIEAEVISSQIVNGRKRMLT
CNVRDASGGLTLRFFNFSMAQKNGLQPGMTIRAFGEIRTGKHQLEIIHPEYKLTAAGESPSLADTLTPIYPTTEGLKQAS
WIRLTAQALEQLEEGGLPELLPESLQPNRLSLADAVRTLHRPPADAELWQLEQGQHPAQQRLVQEELLAHNLSMLKLRER
SNQDAAEPLAATGQLIPRFLESLPFAPTNAQSRVVAEIHADMTKATPMMRLVQGDVGSGKTLVAALSALAAIENGCQVAL
MAPTELLAEQHAANFARWFEPLGLKVGWLAGKLKGKARTQTLEDIASGAAQMIVGTHAIFQEQVSFSRLALTIIDEQHRF
GVHQRLGLREKGIQQGFFPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPITTVAIPDTRRLDVIERVRQAALQD
KRQAYWVCTLIEESEVLECQAAEDTAGGLKEALPELGIGLVHGRMKGAEKQAIMADFKAGKLDLLVATTVIEVGVDVPNA
SLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKAPLSFTAQARLGVLRESNDGFVIAQKDLELRGPGEVLGTRQTG
LAQMKVADLVRDQALIPHIQKLARHLMTQAPDNVDAIIERWLGGREQYVQA
>Mature_691_residues
MQRLDLVPVTELKGVAARVAEKLSKLGVNTVQDLLFHLPLRYEDRTRIYAIDELIPGTTATIEAEVISSQIVNGRKRMLT
CNVRDASGGLTLRFFNFSMAQKNGLQPGMTIRAFGEIRTGKHQLEIIHPEYKLTAAGESPSLADTLTPIYPTTEGLKQAS
WIRLTAQALEQLEEGGLPELLPESLQPNRLSLADAVRTLHRPPADAELWQLEQGQHPAQQRLVQEELLAHNLSMLKLRER
SNQDAAEPLAATGQLIPRFLESLPFAPTNAQSRVVAEIHADMTKATPMMRLVQGDVGSGKTLVAALSALAAIENGCQVAL
MAPTELLAEQHAANFARWFEPLGLKVGWLAGKLKGKARTQTLEDIASGAAQMIVGTHAIFQEQVSFSRLALTIIDEQHRF
GVHQRLGLREKGIQQGFFPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPITTVAIPDTRRLDVIERVRQAALQD
KRQAYWVCTLIEESEVLECQAAEDTAGGLKEALPELGIGLVHGRMKGAEKQAIMADFKAGKLDLLVATTVIEVGVDVPNA
SLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKAPLSFTAQARLGVLRESNDGFVIAQKDLELRGPGEVLGTRQTG
LAQMKVADLVRDQALIPHIQKLARHLMTQAPDNVDAIIERWLGGREQYVQA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=688, Percent_Identity=68.3139534883721, Blast_Score=921, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=387, Percent_Identity=39.5348837209302, Blast_Score=241, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 75717; Mature: 75717

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRLDLVPVTELKGVAARVAEKLSKLGVNTVQDLLFHLPLRYEDRTRIYAIDELIPGTTA
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEEHHCCCCCCC
TIEAEVISSQIVNGRKRMLTCNVRDASGGLTLRFFNFSMAQKNGLQPGMTIRAFGEIRTG
EEHHHHHHHHHHCCCEEEEEEEEEECCCCEEEEEEEEHHHHHCCCCCCCEEEEECCCCCC
KHQLEIIHPEYKLTAAGESPSLADTLTPIYPTTEGLKQASWIRLTAQALEQLEEGGLPEL
CEEEEEECCCEEEEECCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LPESLQPNRLSLADAVRTLHRPPADAELWQLEQGQHPAQQRLVQEELLAHNLSMLKLRER
CHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHH
SNQDAAEPLAATGQLIPRFLESLPFAPTNAQSRVVAEIHADMTKATPMMRLVQGDVGSGK
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TLVAALSALAAIENGCQVALMAPTELLAEQHAANFARWFEPLGLKVGWLAGKLKGKARTQ
HHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCHHHH
TLEDIASGAAQMIVGTHAIFQEQVSFSRLALTIIDEQHRFGVHQRLGLREKGIQQGFFPH
HHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHCCHHHHCCCHHHHHHCCCCCH
QLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPITTVAIPDTRRLDVIERVRQAALQD
HHEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
KRQAYWVCTLIEESEVLECQAAEDTAGGLKEALPELGIGLVHGRMKGAEKQAIMADFKAG
CCCEEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHCCEEEHHHCCCCHHHHHHHHCCCC
KLDLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKAPL
CEEHHHHHHHHHHCCCCCCCEEEEEECCHHCCHHHHHHHHHCCCCCHHHHHEEEEEECCC
SFTAQARLGVLRESNDGFVIAQKDLELRGPGEVLGTRQTGLAQMKVADLVRDQALIPHIQ
CEEHHHHHHHEEECCCCEEEEECCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
KLARHLMTQAPDNVDAIIERWLGGREQYVQA
HHHHHHHHCCCCCHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure
MQRLDLVPVTELKGVAARVAEKLSKLGVNTVQDLLFHLPLRYEDRTRIYAIDELIPGTTA
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEEHHCCCCCCC
TIEAEVISSQIVNGRKRMLTCNVRDASGGLTLRFFNFSMAQKNGLQPGMTIRAFGEIRTG
EEHHHHHHHHHHCCCEEEEEEEEEECCCCEEEEEEEEHHHHHCCCCCCCEEEEECCCCCC
KHQLEIIHPEYKLTAAGESPSLADTLTPIYPTTEGLKQASWIRLTAQALEQLEEGGLPEL
CEEEEEECCCEEEEECCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LPESLQPNRLSLADAVRTLHRPPADAELWQLEQGQHPAQQRLVQEELLAHNLSMLKLRER
CHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHH
SNQDAAEPLAATGQLIPRFLESLPFAPTNAQSRVVAEIHADMTKATPMMRLVQGDVGSGK
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TLVAALSALAAIENGCQVALMAPTELLAEQHAANFARWFEPLGLKVGWLAGKLKGKARTQ
HHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCHHHH
TLEDIASGAAQMIVGTHAIFQEQVSFSRLALTIIDEQHRFGVHQRLGLREKGIQQGFFPH
HHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHCCHHHHCCCHHHHHHCCCCCH
QLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPITTVAIPDTRRLDVIERVRQAALQD
HHEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
KRQAYWVCTLIEESEVLECQAAEDTAGGLKEALPELGIGLVHGRMKGAEKQAIMADFKAG
CCCEEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHCCEEEHHHCCCCHHHHHHHHCCCC
KLDLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKAPL
CEEHHHHHHHHHHCCCCCCCEEEEEECCHHCCHHHHHHHHHCCCCCHHHHHEEEEEECCC
SFTAQARLGVLRESNDGFVIAQKDLELRGPGEVLGTRQTGLAQMKVADLVRDQALIPHIQ
CEEHHHHHHHEEECCCCEEEEECCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
KLARHLMTQAPDNVDAIIERWLGGREQYVQA
HHHHHHHHCCCCCHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]