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The map label for this gene is msrA [H]

Identifier: 119776475

GI number: 119776475

Start: 3971290

End: 3971829

Strand: Direct

Name: msrA [H]

Synonym: Sama_3343

Alternate gene names: 119776475

Gene position: 3971290-3971829 (Clockwise)

Preceding gene: 119776474

Following gene: 119776476

Centisome position: 92.22

GC content: 55.93

Gene sequence:

>540_bases
ATGATGCACAGTTGCCGCACCACAAAGTTGCCACACTCCGCCGCCGATGGCGCAACAAACTTGGCTGGCATTACCCTTGG
CGGCGGTTGCCATTGGTGCACCGAAGCTGTGTTTCAACGCCTGAGTGGGGTAATTGAGGTCGAGCAGGGCTGGGCACGCT
CTAACCCGCCCGCTGATGAATGGTCAGAGGCAGTGACGGTTCACTTTAACCCAGAGCAAATCAGTCTGACGGAGCTGGTT
CGGGTGCACCTGTACACTCACTCCGCCACCAAAGCCCACAGCCTGCGAGGCAAATACCGTTCGGCGCTTTACTCCTGCAA
TGAAAGCCAGCAGCAACAGCTGACTGAGATCCTGGCGACGCTTGCGGACGAATTCCTACAACCCCTCGTCACCCTGATTT
TGCCGCTGGAAGGCTTTAAAGCCTCACCGGCCGAATACCAGAACTATTATCAAACCGACCCAGACAGGCCATTTTGCCAG
GTTTATATTGCCCCCAAGCTTGAAAAGCTGGCGCGGCTATTGGAGGATGACAAGTCGTGA

Upstream 100 bases:

>100_bases
GCCGAACACTTTTCACCTAACGCTGGCCAGCAGAAACGTCACCTGCTGGAAAGTGAAATCCGCTATGGCGGGTCTTATTA
ATTAACAAATGGAGAGGCCT

Downstream 100 bases:

>100_bases
TTTAACCGCAAGGGACCGCCATGGAATACGCACAGGAATACACCAAGCGGGAGAAATGGACGCGGGTGTGCCTGTATTCG
CTGCTTGGATTGCTGCTGAT

Product: methionine sulfoxide reductase A

Products: NA

Alternate protein names: Protein-methionine-S-oxide reductase; Peptide-methionine (S)-S-oxide reductase; Peptide Met(O) reductase [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MMHSCRTTKLPHSAADGATNLAGITLGGGCHWCTEAVFQRLSGVIEVEQGWARSNPPADEWSEAVTVHFNPEQISLTELV
RVHLYTHSATKAHSLRGKYRSALYSCNESQQQQLTEILATLADEFLQPLVTLILPLEGFKASPAEYQNYYQTDPDRPFCQ
VYIAPKLEKLARLLEDDKS

Sequences:

>Translated_179_residues
MMHSCRTTKLPHSAADGATNLAGITLGGGCHWCTEAVFQRLSGVIEVEQGWARSNPPADEWSEAVTVHFNPEQISLTELV
RVHLYTHSATKAHSLRGKYRSALYSCNESQQQQLTEILATLADEFLQPLVTLILPLEGFKASPAEYQNYYQTDPDRPFCQ
VYIAPKLEKLARLLEDDKS
>Mature_179_residues
MMHSCRTTKLPHSAADGATNLAGITLGGGCHWCTEAVFQRLSGVIEVEQGWARSNPPADEWSEAVTVHFNPEQISLTELV
RVHLYTHSATKAHSLRGKYRSALYSCNESQQQQLTEILATLADEFLQPLVTLILPLEGFKASPAEYQNYYQTDPDRPFCQ
VYIAPKLEKLARLLEDDKS

Specific function: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine [H]

COG id: COG0225

COG function: function code O; Peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrA Met sulfoxide reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002569 [H]

Pfam domain/function: PF01625 PMSR [H]

EC number: =1.8.4.11 [H]

Molecular weight: Translated: 20020; Mature: 20020

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHSCRTTKLPHSAADGATNLAGITLGGGCHWCTEAVFQRLSGVIEVEQGWARSNPPADE
CCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCEEECCCCCCCCCCCHHH
WSEAVTVHFNPEQISLTELVRVHLYTHSATKAHSLRGKYRSALYSCNESQQQQLTEILAT
HHCEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LADEFLQPLVTLILPLEGFKASPAEYQNYYQTDPDRPFCQVYIAPKLEKLARLLEDDKS
HHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCC
>Mature Secondary Structure
MMHSCRTTKLPHSAADGATNLAGITLGGGCHWCTEAVFQRLSGVIEVEQGWARSNPPADE
CCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCEEECCCCCCCCCCCHHH
WSEAVTVHFNPEQISLTELVRVHLYTHSATKAHSLRGKYRSALYSCNESQQQQLTEILAT
HHCEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LADEFLQPLVTLILPLEGFKASPAEYQNYYQTDPDRPFCQVYIAPKLEKLARLLEDDKS
HHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA