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The map label for this gene is aprE [H]

Identifier: 119776392

GI number: 119776392

Start: 3868126

End: 3869508

Strand: Direct

Name: aprE [H]

Synonym: Sama_3260

Alternate gene names: 119776392

Gene position: 3868126-3869508 (Clockwise)

Preceding gene: 119776391

Following gene: 119776393

Centisome position: 89.83

GC content: 50.47

Gene sequence:

>1383_bases
ATGAGTAAAGCACTGACAGCAAGGGATCTTGAGATGGTCGATGACGTATATGGCGCCATGATGACCGATGCACCTACCAG
CCACAGACTCACTATCTGGGCACTCACATCGTTGATATTTGCCTTCCTTATCTGGGCGTATTTTGCTGAGCTGGATCAGG
TTACCGTGGGTACAGGCAAGGTTATCCCCTCGTCGCAAATTCAGGTTATTCAAAGTCTGGACGGCGGTGTACTGCAAGAA
CTGTTCGTGCGCGAAGGCAATATAGTCGCCAAGGGAGAACCTTTGGCACGTATTGATGACACCCGCTTCCGCTCAGACTT
TGCCCAACAGGAAGAAGAGGTGTTCAGCTTACAGGCAAATGTGATCCGTATGCGGACTGAGCTGAACAGTATTACTGTGT
CAGATATGGCATCAGACTGGCGAGAGCAGGTTCGAATCGTCAAACAGGAACTGATATTCCCCGACGCTCTTAGCGCACAA
AAAGCTGAATTGGTCGCGCGTCAACAAGCCGAGTATAACGGTCGACTCGACAATCTGGAAAACCAACTGGAGATTCTGGC
CAGGCAAATTCAGCAGCGTCAGCAAGAAAATGAAGAGCTGACTACCAAGATAGCGACCATGACCACCAGTTTTCAGCTCA
TCAGCCGAGAACTGGAACTTACCCGTCCCCTGGCGCAAAAAGGCATTGTGCCTGAGGTTGAATTACTGAAGCTTGAACGC
ACCGTGAACGAACTCCAGGGTGAGCTCAAAGCCATGCGTCAGCTCAGACCTAAAATTAAAGCCACGCTGGATGAAGCCAT
ATTAAAACGCCGTGAAGCCGTGTTTGTATTCGCCGCTGATACCCGTGCCCAGCTAAACGACATGCAAACCCGTTTGTCGC
GTATGAGTGAGGCGCAGGTAGGGGCACAGGATAAGGTGAGTAAAGCCGTCATTACTTCCCCCGTGAATGGCACAGTGAAA
ACCGTCCACATCAACACACTCGGCGGCGTGGTGCAGCCCGGGGTAGATATTATGGAAATTGTGCCATCGGAAGACCAACT
GCTTATCGAGGCCAAGATCACCCCCAAAGACATTGCGTTTTTACATGTTGGCTTGCCTGCCGTAGTTAAGGTAACGGCCT
ATGATTTTACCCGCTACGGCGGGTTACAAGGCACTGTTGAGCACATCAGTGCCGATACCACCCAGGACGAAGAAGGTAAC
AGCTTTTATCTGATACGCGTCAGGACCGCAGAGTCCAGCTTGGTTAAAGACGATGGCACGGAGATGCCAATTATCCCCGG
GATGCTGACCTCTGTGGATGTCATCACCGGACAAAGATCTATTCTTGAATACATACTTAATCCAATTCTAAGAGCCAAAG
ACACCGCACTTAGGGAACGATGA

Upstream 100 bases:

>100_bases
GGGTGATCGTATTAGACAGAGGTCATGTACTGGCCGATGGACCCAAAAACGACGTTCTTGAAAAACTGAGTCTGGGGCTG
CTTGCTGGAGGTGCAAAGGG

Downstream 100 bases:

>100_bases
GGCTCTAACTAAACCGGGAGGGTTTATCAATGAACAAGAAACGCTTGCAACAGTTGCGCTTGGGCGTACTGGCTGCAGCC
ATAGGCGGCATCATGATGCC

Product: HlyD family secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MSKALTARDLEMVDDVYGAMMTDAPTSHRLTIWALTSLIFAFLIWAYFAELDQVTVGTGKVIPSSQIQVIQSLDGGVLQE
LFVREGNIVAKGEPLARIDDTRFRSDFAQQEEEVFSLQANVIRMRTELNSITVSDMASDWREQVRIVKQELIFPDALSAQ
KAELVARQQAEYNGRLDNLENQLEILARQIQQRQQENEELTTKIATMTTSFQLISRELELTRPLAQKGIVPEVELLKLER
TVNELQGELKAMRQLRPKIKATLDEAILKRREAVFVFAADTRAQLNDMQTRLSRMSEAQVGAQDKVSKAVITSPVNGTVK
TVHINTLGGVVQPGVDIMEIVPSEDQLLIEAKITPKDIAFLHVGLPAVVKVTAYDFTRYGGLQGTVEHISADTTQDEEGN
SFYLIRVRTAESSLVKDDGTEMPIIPGMLTSVDVITGQRSILEYILNPILRAKDTALRER

Sequences:

>Translated_460_residues
MSKALTARDLEMVDDVYGAMMTDAPTSHRLTIWALTSLIFAFLIWAYFAELDQVTVGTGKVIPSSQIQVIQSLDGGVLQE
LFVREGNIVAKGEPLARIDDTRFRSDFAQQEEEVFSLQANVIRMRTELNSITVSDMASDWREQVRIVKQELIFPDALSAQ
KAELVARQQAEYNGRLDNLENQLEILARQIQQRQQENEELTTKIATMTTSFQLISRELELTRPLAQKGIVPEVELLKLER
TVNELQGELKAMRQLRPKIKATLDEAILKRREAVFVFAADTRAQLNDMQTRLSRMSEAQVGAQDKVSKAVITSPVNGTVK
TVHINTLGGVVQPGVDIMEIVPSEDQLLIEAKITPKDIAFLHVGLPAVVKVTAYDFTRYGGLQGTVEHISADTTQDEEGN
SFYLIRVRTAESSLVKDDGTEMPIIPGMLTSVDVITGQRSILEYILNPILRAKDTALRER
>Mature_459_residues
SKALTARDLEMVDDVYGAMMTDAPTSHRLTIWALTSLIFAFLIWAYFAELDQVTVGTGKVIPSSQIQVIQSLDGGVLQEL
FVREGNIVAKGEPLARIDDTRFRSDFAQQEEEVFSLQANVIRMRTELNSITVSDMASDWREQVRIVKQELIFPDALSAQK
AELVARQQAEYNGRLDNLENQLEILARQIQQRQQENEELTTKIATMTTSFQLISRELELTRPLAQKGIVPEVELLKLERT
VNELQGELKAMRQLRPKIKATLDEAILKRREAVFVFAADTRAQLNDMQTRLSRMSEAQVGAQDKVSKAVITSPVNGTVKT
VHINTLGGVVQPGVDIMEIVPSEDQLLIEAKITPKDIAFLHVGLPAVVKVTAYDFTRYGGLQGTVEHISADTTQDEEGNS
FYLIRVRTAESSLVKDDGTEMPIIPGMLTSVDVITGQRSILEYILNPILRAKDTALRER

Specific function: Involved in the secretion of alkaline protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 51439; Mature: 51308

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKALTARDLEMVDDVYGAMMTDAPTSHRLTIWALTSLIFAFLIWAYFAELDQVTVGTGK
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEECCCC
VIPSSQIQVIQSLDGGVLQELFVREGNIVAKGEPLARIDDTRFRSDFAQQEEEVFSLQAN
CCCCHHHHHHHHCCCHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VIRMRTELNSITVSDMASDWREQVRIVKQELIFPDALSAQKAELVARQQAEYNGRLDNLE
HHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHH
NQLEILARQIQQRQQENEELTTKIATMTTSFQLISRELELTRPLAQKGIVPEVELLKLER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
TVNELQGELKAMRQLRPKIKATLDEAILKRREAVFVFAADTRAQLNDMQTRLSRMSEAQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHC
GAQDKVSKAVITSPVNGTVKTVHINTLGGVVQPGVDIMEIVPSEDQLLIEAKITPKDIAF
CCHHHHHHHHEECCCCCCEEEEEEECCCCCCCCCCHHHEECCCCCCEEEEEECCCCCEEE
LHVGLPAVVKVTAYDFTRYGGLQGTVEHISADTTQDEEGNSFYLIRVRTAESSLVKDDGT
EEECCCHHEEEEEHHHHHHCCCCHHHHHHCCCCCCCCCCCEEEEEEEEECCCHHHCCCCC
EMPIIPGMLTSVDVITGQRSILEYILNPILRAKDTALRER
CCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKALTARDLEMVDDVYGAMMTDAPTSHRLTIWALTSLIFAFLIWAYFAELDQVTVGTGK
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEECCCC
VIPSSQIQVIQSLDGGVLQELFVREGNIVAKGEPLARIDDTRFRSDFAQQEEEVFSLQAN
CCCCHHHHHHHHCCCHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VIRMRTELNSITVSDMASDWREQVRIVKQELIFPDALSAQKAELVARQQAEYNGRLDNLE
HHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHH
NQLEILARQIQQRQQENEELTTKIATMTTSFQLISRELELTRPLAQKGIVPEVELLKLER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
TVNELQGELKAMRQLRPKIKATLDEAILKRREAVFVFAADTRAQLNDMQTRLSRMSEAQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHC
GAQDKVSKAVITSPVNGTVKTVHINTLGGVVQPGVDIMEIVPSEDQLLIEAKITPKDIAF
CCHHHHHHHHEECCCCCCEEEEEEECCCCCCCCCCHHHEECCCCCCEEEEEECCCCCEEE
LHVGLPAVVKVTAYDFTRYGGLQGTVEHISADTTQDEEGNSFYLIRVRTAESSLVKDDGT
EEECCCHHEEEEEHHHHHHCCCCHHHHHHCCCCCCCCCCCEEEEEEEEECCCHHHCCCCC
EMPIIPGMLTSVDVITGQRSILEYILNPILRAKDTALRER
CCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]