Click here to switch to the map view.

The map label for this gene is hemY [H]

Identifier: 119776389

GI number: 119776389

Start: 3851736

End: 3852902

Strand: Direct

Name: hemY [H]

Synonym: Sama_3257

Alternate gene names: 119776389

Gene position: 3851736-3852902 (Clockwise)

Preceding gene: 119776388

Following gene: 119776390

Centisome position: 89.45

GC content: 52.27

Gene sequence:

>1167_bases
ATGATAAAAACGCTCATTTATCTTGGCATTATTCTGATTGGGCTCTGCTTGAGCCCCTACATTGTTGGCAACACCGGCTA
TCTGTATTTGTCAGCCTGGGGCTACGAAATTGAAACCAGTCTGGTGTTTGCCATTGTCGTGCTGGTGATTGCCTACGGCG
TTATCGTGATTGCCGAATGGATAGCCGTTAAAAGCATCAGCTTGGTGCTGGGCAGCCGTTATCTGCCCGAACGCTGGCGA
CGCAATGCCGCCAAACGCCATACCCTGAACGGAGCACTGGCGCTTGCTGAAGAAAACTGGCCCGATGCTGAGCGCTTTAT
GGCCAAGGGAGCCGCCAAAGGTGAGCTGCCAGCACTGAATCTGCTCGCTGCAGCGAGGGCGGCTCAGCATCAGGGAAAAT
ATGCCGAGCGTGATGACTATCTTGAAAAAGCTGTAACAGAGCCGAATGCGGCGACGGCCGTATTTACAACCCGCACCCGC
TATCTGCTTAAACAGGGCCAATTGGAGCGTGCCAGAACTGCACTCAATCATTTGGCGCCGACCAGCAAAAGCAGCGCTGC
GGTGATCAAACTTGCCATGGAAGTCTATCTTGCCCAGCAGGATTGGCGGGCAGTGAGAGAATTGTTACCTGCCATCAAGA
AGCACGCACTGCTTAATGATGCCAATTTTGAAGATTTATCTGTCAGAGTAAGCGTGAAGCTGCTGGAGCAGGCTGGCAGC
AAAGATTGGGACAGTCTGGATAAAGAATGGCAGTGGCTATCCCGCAGCGAAAAACAGCTCAGTGCCAATCGTGCTGCCTA
TGCACTTGGGCTTGCCAAACAAGGTAAAAAGGCCGAAGCCGTTAAACTGCTTCTTAAAGATCTGGAATCTTTGCCCGATC
CTCAAGTTCTGGCGCTGCTTCCCCAAGTCCTAAATGGTCAGGATGAGGCTCCAAGGCAACAGTTGCTCAAGCTGGCACCC
AGGTTCGAGGATGTGCATGAATATCACGAATGTGTGGCACGACTTTGCCAGCAAGCCAGGGAGTTTAAGACTGCCTACGA
GCATTGGCGTAAAGCCTGTGAGTTAAATCCATCCAAAGAAAATTGGTTGGCACTCGCCGAGCTCGACGAGCAACTGGGCA
ATACCGACCTGGCGTTACAACATTACCGGAGGGCTGCCAAAGCCTGA

Upstream 100 bases:

>100_bases
AGCCAATCCCCGATCCCACGCCAATACCGGCAGTGAATCCGCTGCCCGAACCGGATCAGGAACCAGAACCTTCTGCGGCA
GCCGAATCGGAGGCTGAGGC

Downstream 100 bases:

>100_bases
CGCCACTCCCTAGCAACATTTTAGTAACCTAAACAAGGCGTTTTCGTGGATTTTTCCATGAAAACGCTTTTTTTTCACTT
ATCGCCTACACTATATATAG

Product: HemY protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MIKTLIYLGIILIGLCLSPYIVGNTGYLYLSAWGYEIETSLVFAIVVLVIAYGVIVIAEWIAVKSISLVLGSRYLPERWR
RNAAKRHTLNGALALAEENWPDAERFMAKGAAKGELPALNLLAAARAAQHQGKYAERDDYLEKAVTEPNAATAVFTTRTR
YLLKQGQLERARTALNHLAPTSKSSAAVIKLAMEVYLAQQDWRAVRELLPAIKKHALLNDANFEDLSVRVSVKLLEQAGS
KDWDSLDKEWQWLSRSEKQLSANRAAYALGLAKQGKKAEAVKLLLKDLESLPDPQVLALLPQVLNGQDEAPRQQLLKLAP
RFEDVHEYHECVARLCQQAREFKTAYEHWRKACELNPSKENWLALAELDEQLGNTDLALQHYRRAAKA

Sequences:

>Translated_388_residues
MIKTLIYLGIILIGLCLSPYIVGNTGYLYLSAWGYEIETSLVFAIVVLVIAYGVIVIAEWIAVKSISLVLGSRYLPERWR
RNAAKRHTLNGALALAEENWPDAERFMAKGAAKGELPALNLLAAARAAQHQGKYAERDDYLEKAVTEPNAATAVFTTRTR
YLLKQGQLERARTALNHLAPTSKSSAAVIKLAMEVYLAQQDWRAVRELLPAIKKHALLNDANFEDLSVRVSVKLLEQAGS
KDWDSLDKEWQWLSRSEKQLSANRAAYALGLAKQGKKAEAVKLLLKDLESLPDPQVLALLPQVLNGQDEAPRQQLLKLAP
RFEDVHEYHECVARLCQQAREFKTAYEHWRKACELNPSKENWLALAELDEQLGNTDLALQHYRRAAKA
>Mature_388_residues
MIKTLIYLGIILIGLCLSPYIVGNTGYLYLSAWGYEIETSLVFAIVVLVIAYGVIVIAEWIAVKSISLVLGSRYLPERWR
RNAAKRHTLNGALALAEENWPDAERFMAKGAAKGELPALNLLAAARAAQHQGKYAERDDYLEKAVTEPNAATAVFTTRTR
YLLKQGQLERARTALNHLAPTSKSSAAVIKLAMEVYLAQQDWRAVRELLPAIKKHALLNDANFEDLSVRVSVKLLEQAGS
KDWDSLDKEWQWLSRSEKQLSANRAAYALGLAKQGKKAEAVKLLLKDLESLPDPQVLALLPQVLNGQDEAPRQQLLKLAP
RFEDVHEYHECVARLCQQAREFKTAYEHWRKACELNPSKENWLALAELDEQLGNTDLALQHYRRAAKA

Specific function: Involved in a late step of protoheme IX synthesis [H]

COG id: COG3071

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790234, Length=316, Percent_Identity=25.6329113924051, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010817
- InterPro:   IPR005254
- InterPro:   IPR011990 [H]

Pfam domain/function: PF07219 HemY_N [H]

EC number: NA

Molecular weight: Translated: 43548; Mature: 43548

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKTLIYLGIILIGLCLSPYIVGNTGYLYLSAWGYEIETSLVFAIVVLVIAYGVIVIAEW
CHHHHHHHHHHHHHHHHCCEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
IAVKSISLVLGSRYLPERWRRNAAKRHTLNGALALAEENWPDAERFMAKGAAKGELPALN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHEEECCCCCCCHHHHHHCCCCCCCCCHHH
LLAAARAAQHQGKYAERDDYLEKAVTEPNAATAVFTTRTRYLLKQGQLERARTALNHLAP
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCHHHHHHHHHHHHCC
TSKSSAAVIKLAMEVYLAQQDWRAVRELLPAIKKHALLNDANFEDLSVRVSVKLLEQAGS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
KDWDSLDKEWQWLSRSEKQLSANRAAYALGLAKQGKKAEAVKLLLKDLESLPDPQVLALL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHH
PQVLNGQDEAPRQQLLKLAPRFEDVHEYHECVARLCQQAREFKTAYEHWRKACELNPSKE
HHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
NWLALAELDEQLGNTDLALQHYRRAAKA
HHHHHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKTLIYLGIILIGLCLSPYIVGNTGYLYLSAWGYEIETSLVFAIVVLVIAYGVIVIAEW
CHHHHHHHHHHHHHHHHCCEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
IAVKSISLVLGSRYLPERWRRNAAKRHTLNGALALAEENWPDAERFMAKGAAKGELPALN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHEEECCCCCCCHHHHHHCCCCCCCCCHHH
LLAAARAAQHQGKYAERDDYLEKAVTEPNAATAVFTTRTRYLLKQGQLERARTALNHLAP
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCHHHHHHHHHHHHCC
TSKSSAAVIKLAMEVYLAQQDWRAVRELLPAIKKHALLNDANFEDLSVRVSVKLLEQAGS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
KDWDSLDKEWQWLSRSEKQLSANRAAYALGLAKQGKKAEAVKLLLKDLESLPDPQVLALL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHH
PQVLNGQDEAPRQQLLKLAPRFEDVHEYHECVARLCQQAREFKTAYEHWRKACELNPSKE
HHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
NWLALAELDEQLGNTDLALQHYRRAAKA
HHHHHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]