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The map label for this gene is fis

Identifier: 119776358

GI number: 119776358

Start: 3819669

End: 3819974

Strand: Direct

Name: fis

Synonym: Sama_3226

Alternate gene names: 119776358

Gene position: 3819669-3819974 (Clockwise)

Preceding gene: 119776357

Following gene: 119776361

Centisome position: 88.7

GC content: 53.27

Gene sequence:

>306_bases
ATGTTTGATCAGACAACTCACACTGAAGCTCATCCGCTTACCGTAGGCAAAATCGAAACCGCAAACGGCACCATCAAGCC
GCAACTGCTGCGTGATGCCGTTAAGCGCGCTGTTAGCAACTTCTTCGCCCAGCTGGATGGCCAGGAAGCCCAGGAAGTCT
ACGAAATGGTGCTTTGCGAAGTTGAAGCCCCTCTGCTTGATATCATCATGCAACACACCCGCGGCAACCAAACCCGCGCA
GCCAACATGCTGGGTATCAACCGTGGCACCCTGCGCAAGAAGCTGAAAAAGTACGGCATGAACTAA

Upstream 100 bases:

>100_bases
GTTCCCAGTTTAATGCGCTGGAAACCGCTGCCGAGCAACGTTCCGCTGTGGAACGTTATTTCGACGAATTAGTACAGTAT
CAATAAAGAGCAGAATACGA

Downstream 100 bases:

>100_bases
TCCCTCGGGATTAACATACTGTTGAAGAGGGCCCGGTATTCTTACCGGGCTTTTTTTTGACCGCTGCGATTACGACTGAA
ATAGCTGCTGCAATAGAAGC

Product: DNA-binding protein Fis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MFDQTTHTEAHPLTVGKIETANGTIKPQLLRDAVKRAVSNFFAQLDGQEAQEVYEMVLCEVEAPLLDIIMQHTRGNQTRA
ANMLGINRGTLRKKLKKYGMN

Sequences:

>Translated_101_residues
MFDQTTHTEAHPLTVGKIETANGTIKPQLLRDAVKRAVSNFFAQLDGQEAQEVYEMVLCEVEAPLLDIIMQHTRGNQTRA
ANMLGINRGTLRKKLKKYGMN
>Mature_101_residues
MFDQTTHTEAHPLTVGKIETANGTIKPQLLRDAVKRAVSNFFAQLDGQEAQEVYEMVLCEVEAPLLDIIMQHTRGNQTRA
ANMLGINRGTLRKKLKKYGMN

Specific function: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters

COG id: COG2901

COG function: function code KL; Factor for inversion stimulation Fis, transcriptional activator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory fis family

Homologues:

Organism=Escherichia coli, GI1789661, Length=102, Percent_Identity=60.7843137254902, Blast_Score=125, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FIS_SHEAM (A1SAM2)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_929098.1
- ProteinModelPortal:   A1SAM2
- SMR:   A1SAM2
- STRING:   A1SAM2
- GeneID:   4605473
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_3226
- NMPDR:   fig|326297.7.peg.3038
- eggNOG:   COG2901
- HOGENOM:   HBG509520
- OMA:   EMVLCEV
- PhylomeDB:   A1SAM2
- ProtClustDB:   PRK00430
- HAMAP:   MF_00166
- InterPro:   IPR005412
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- PIRSF:   PIRSF002097
- PRINTS:   PR01591
- PRINTS:   PR01590

Pfam domain/function: PF02954 HTH_8; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 11356; Mature: 11356

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDQTTHTEAHPLTVGKIETANGTIKPQLLRDAVKRAVSNFFAQLDGQEAQEVYEMVLCE
CCCCCCCCCCCCEEECEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VEAPLLDIIMQHTRGNQTRAANMLGINRGTLRKKLKKYGMN
CCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MFDQTTHTEAHPLTVGKIETANGTIKPQLLRDAVKRAVSNFFAQLDGQEAQEVYEMVLCE
CCCCCCCCCCCCEEECEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VEAPLLDIIMQHTRGNQTRAANMLGINRGTLRKKLKKYGMN
CCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA