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The map label for this gene is agaR [H]

Identifier: 119776051

GI number: 119776051

Start: 3470807

End: 3471580

Strand: Reverse

Name: agaR [H]

Synonym: Sama_2919

Alternate gene names: 119776051

Gene position: 3471580-3470807 (Counterclockwise)

Preceding gene: 119776053

Following gene: 119776043

Centisome position: 80.62

GC content: 53.36

Gene sequence:

>774_bases
ATGCTCGATTATGCTTCCTTTCCGGATCAAAGGCAAACCCTGATTAAAACGCGCCTGCTACAGGATGGCAGAGTCGTCTG
CGCTCAGCTCGCAGCCGAACTGGGTGTATCTGAACACACTATCCGGCGCGATTTGCAGGAACTGGCCAGTCAGGGCGTTT
GCAAAAAGGTCTATGGCGGCGCTGTGAATGTGGTGGCAGATCCGCCGGGTTTAGCCGAGCGCATTCATCTGACAGGTGAA
GAAAAGCAGAAACTTGGCCGGGCCAGTGCGCAGCTTTTGCGGGCCGGTGATTGCGTTTTTGTGGATTCGGGCAGCACCAA
TATGGCAATCGCCAAAGCGATAAGCCAGCAGCAAGCCATCACCTTTGTTACCCATGTGCCTGAAATTGCGGTTGAATTGC
TGAAGTTGGCGCACTGTGAAGTGATTTTGTTGGGGGGGAAACTGAACCGGAAGATTGGCGCATCGGTTGGCCCCGCAACC
ATCAGGCAGCTGGAAACCATGTACTTCGACCAATGCCTGCTGGGAGCCTGCGCACTCGACCCTGAAGAAGGGGTGACGGT
ATTTGATTTCGATGATGCAGAATTTAAACGGACTATCGTCAAGCAAAGCAGTGAGGTTATTGTTGCGCTGACCCAAGACA
AGTTGGGGACGGTAGCCAAACACAGGGTGATGCAGGTGAGTGAGATTTCCACTCTGGTGCTTGCAGGCGCGTCTGTGCCG
GGTGTGCTGGCAAAGTTGGCACAATCAAACGTCAATATTGTGCAGGCAGATTAA

Upstream 100 bases:

>100_bases
ATACCGGGGCATATGCTTTATCCCGGCTCACCTTTTCATTGATAAATGGAGCATGAACGCGCTAGCATGAGCCATGCTTG
TTGATAATTCATGATAAATT

Downstream 100 bases:

>100_bases
AAGCGTATGCAGACACTATGTGGCGGGCAGTGACACAGGGCATGGTGTTTATTCAAAGCCTGTACACTCTATCCTGCTTA
TGGTGATGTGGGGTGATTCA

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLDYASFPDQRQTLIKTRLLQDGRVVCAQLAAELGVSEHTIRRDLQELASQGVCKKVYGGAVNVVADPPGLAERIHLTGE
EKQKLGRASAQLLRAGDCVFVDSGSTNMAIAKAISQQQAITFVTHVPEIAVELLKLAHCEVILLGGKLNRKIGASVGPAT
IRQLETMYFDQCLLGACALDPEEGVTVFDFDDAEFKRTIVKQSSEVIVALTQDKLGTVAKHRVMQVSEISTLVLAGASVP
GVLAKLAQSNVNIVQAD

Sequences:

>Translated_257_residues
MLDYASFPDQRQTLIKTRLLQDGRVVCAQLAAELGVSEHTIRRDLQELASQGVCKKVYGGAVNVVADPPGLAERIHLTGE
EKQKLGRASAQLLRAGDCVFVDSGSTNMAIAKAISQQQAITFVTHVPEIAVELLKLAHCEVILLGGKLNRKIGASVGPAT
IRQLETMYFDQCLLGACALDPEEGVTVFDFDDAEFKRTIVKQSSEVIVALTQDKLGTVAKHRVMQVSEISTLVLAGASVP
GVLAKLAQSNVNIVQAD
>Mature_257_residues
MLDYASFPDQRQTLIKTRLLQDGRVVCAQLAAELGVSEHTIRRDLQELASQGVCKKVYGGAVNVVADPPGLAERIHLTGE
EKQKLGRASAQLLRAGDCVFVDSGSTNMAIAKAISQQQAITFVTHVPEIAVELLKLAHCEVILLGGKLNRKIGASVGPAT
IRQLETMYFDQCLLGACALDPEEGVTVFDFDDAEFKRTIVKQSSEVIVALTQDKLGTVAKHRVMQVSEISTLVLAGASVP
GVLAKLAQSNVNIVQAD

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=249, Percent_Identity=27.3092369477912, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787540, Length=245, Percent_Identity=28.1632653061224, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI226510968, Length=229, Percent_Identity=30.1310043668122, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789829, Length=213, Percent_Identity=30.5164319248826, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788069, Length=246, Percent_Identity=26.4227642276423, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789059, Length=250, Percent_Identity=25.6, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=24.8908296943231, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790635, Length=249, Percent_Identity=23.2931726907631, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082344, Length=252, Percent_Identity=22.6190476190476, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790753, Length=248, Percent_Identity=27.8225806451613, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787063, Length=209, Percent_Identity=25.8373205741627, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27562; Mature: 27562

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDYASFPDQRQTLIKTRLLQDGRVVCAQLAAELGVSEHTIRRDLQELASQGVCKKVYGG
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCC
AVNVVADPPGLAERIHLTGEEKQKLGRASAQLLRAGDCVFVDSGSTNMAIAKAISQQQAI
EEEEEECCCCHHHEEECCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHH
TFVTHVPEIAVELLKLAHCEVILLGGKLNRKIGASVGPATIRQLETMYFDQCLLGACALD
HHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PEEGVTVFDFDDAEFKRTIVKQSSEVIVALTQDKLGTVAKHRVMQVSEISTLVLAGASVP
CCCCCEEEECCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
GVLAKLAQSNVNIVQAD
HHHHHHHHCCCEEEECC
>Mature Secondary Structure
MLDYASFPDQRQTLIKTRLLQDGRVVCAQLAAELGVSEHTIRRDLQELASQGVCKKVYGG
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCC
AVNVVADPPGLAERIHLTGEEKQKLGRASAQLLRAGDCVFVDSGSTNMAIAKAISQQQAI
EEEEEECCCCHHHEEECCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHH
TFVTHVPEIAVELLKLAHCEVILLGGKLNRKIGASVGPATIRQLETMYFDQCLLGACALD
HHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PEEGVTVFDFDDAEFKRTIVKQSSEVIVALTQDKLGTVAKHRVMQVSEISTLVLAGASVP
CCCCCEEEECCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
GVLAKLAQSNVNIVQAD
HHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]