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The map label for this gene is obgE

Identifier: 119775959

GI number: 119775959

Start: 3365225

End: 3366394

Strand: Reverse

Name: obgE

Synonym: Sama_2827

Alternate gene names: 119775959

Gene position: 3366394-3365225 (Counterclockwise)

Preceding gene: 119775960

Following gene: 119775958

Centisome position: 78.18

GC content: 55.04

Gene sequence:

>1170_bases
ATGAAGTTCGTCGACGAGGCGGTCATTAAGGTTCAGGCCGGTGACGGTGGCAGCGGTTGCGTAAGCTTTCGCCGTGAAAA
ATACATTCCCGATGGTGGTCCCGATGGGGGCGACGGTGGCGATGGCGGCAGTGTGTATCTGGTGGCCGACGCCAGCCTCA
ATACCCTGATTGATTACCGCTTTGAGCGTTTTTACCTTGCTGAGCGTGGTGAAAACGGTCGTGGTCGTGACTGCACCGGT
AAAGGTGGCAGCGATCTGACCCTGCGTGTTCCCGTAGGTACCCGTGCCGTAGACATAGATACCGACGAAGTGCTGGGTGA
TTTGACCGAAGTCGGTCAAAAACTGTTGGTGGCCAAGGGTGGATTCCACGGTTTGGGTAACACCCGTTTTAAAAGCAGTG
TAAACCGTGCTCCACGCCAGAAAACCCTGGGTACCAAGGGTGAGGTTCGTGAGCTGCGCCTCGAGCTGTTGCTGCTGGCG
GATGTGGGTCTGCTGGGGATGCCAAACGCCGGTAAATCAACCTTCATTCGCGCAGTTTCCCGTGCGACACCCAAGGTGGC
TGATTATCCCTTTACCACTCTGGTGCCAAACCTTGGCGTAGTGAACCCGCGCCCCGGTCAGAGCTTTGTCATTGCCGACA
TTCCGGGTTTGATTGAAGGCGCCGCCGAAGGTGCCGGCCTGGGTATTCGCTTCTTGAAGCACCTGGAACGTTGCCGCGTG
CTGCTGCACATTTTGGATATCGAGCCCATCGATGGCTCAAGCCCTGCTGAAAGCGCCCGCGCTATTGTTGCCGAGCTTGA
AAAGTATTCACCTGAACTGGCTGCCAAGCCCCGCTGGTTGGTATTCAACAAAACCGACCTGCTGCTTGAAGAAGAATTGC
AGGAACGTGTTGATGCCATTGTGGCTGAGCTTGGCTGGGAAGGCGATGTGTACACCATGTCTGCCGCGACCCGTGAGGGT
ACCAAAGAGCTGGCTGAAAAGCTGTTCGACTTCATCAAGAGCTTGCCAGATGAAGCCGCTGCCGCCGATCCTGACAAGGA
AGTGGAGTTCAAGTGGGACAATTACCACAAGGCTCAGCTAGACGATCTGAACCCGGATTTTGATGATTCGGATGATGACG
ATGATTTCGATGATGACGACTACGACGTGGAAGTCATTTACCAGAGATAA

Upstream 100 bases:

>100_bases
GCTTTTGTTTTGTCTGGGGCTTTGCCCTATGTTTGATAGAGATTTTGGTCTGCCGCGCTGCAGGCGGTATAATTGCCCCA
TTCTGTGGTGAGGAGTTGAT

Downstream 100 bases:

>100_bases
GCCTTCAATCGGGGATAGCGGTGTACGCAGATACCCAGAATGACATAACCCGGCAGGTGGTGCGCGTCGCGCAGCTCCTG
CTGGCCTATGGCGCCGAGTC

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKFVDEAVIKVQAGDGGSGCVSFRREKYIPDGGPDGGDGGDGGSVYLVADASLNTLIDYRFERFYLAERGENGRGRDCTG
KGGSDLTLRVPVGTRAVDIDTDEVLGDLTEVGQKLLVAKGGFHGLGNTRFKSSVNRAPRQKTLGTKGEVRELRLELLLLA
DVGLLGMPNAGKSTFIRAVSRATPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAAEGAGLGIRFLKHLERCRV
LLHILDIEPIDGSSPAESARAIVAELEKYSPELAAKPRWLVFNKTDLLLEEELQERVDAIVAELGWEGDVYTMSAATREG
TKELAEKLFDFIKSLPDEAAAADPDKEVEFKWDNYHKAQLDDLNPDFDDSDDDDDFDDDDYDVEVIYQR

Sequences:

>Translated_389_residues
MKFVDEAVIKVQAGDGGSGCVSFRREKYIPDGGPDGGDGGDGGSVYLVADASLNTLIDYRFERFYLAERGENGRGRDCTG
KGGSDLTLRVPVGTRAVDIDTDEVLGDLTEVGQKLLVAKGGFHGLGNTRFKSSVNRAPRQKTLGTKGEVRELRLELLLLA
DVGLLGMPNAGKSTFIRAVSRATPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAAEGAGLGIRFLKHLERCRV
LLHILDIEPIDGSSPAESARAIVAELEKYSPELAAKPRWLVFNKTDLLLEEELQERVDAIVAELGWEGDVYTMSAATREG
TKELAEKLFDFIKSLPDEAAAADPDKEVEFKWDNYHKAQLDDLNPDFDDSDDDDDFDDDDYDVEVIYQR
>Mature_389_residues
MKFVDEAVIKVQAGDGGSGCVSFRREKYIPDGGPDGGDGGDGGSVYLVADASLNTLIDYRFERFYLAERGENGRGRDCTG
KGGSDLTLRVPVGTRAVDIDTDEVLGDLTEVGQKLLVAKGGFHGLGNTRFKSSVNRAPRQKTLGTKGEVRELRLELLLLA
DVGLLGMPNAGKSTFIRAVSRATPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAAEGAGLGIRFLKHLERCRV
LLHILDIEPIDGSSPAESARAIVAELEKYSPELAAKPRWLVFNKTDLLLEEELQERVDAIVAELGWEGDVYTMSAATREG
TKELAEKLFDFIKSLPDEAAAADPDKEVEFKWDNYHKAQLDDLNPDFDDSDDDDDFDDDDYDVEVIYQR

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=343, Percent_Identity=40.8163265306122, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI111955139, Length=387, Percent_Identity=32.8165374677003, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI111955063, Length=221, Percent_Identity=35.2941176470588, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI4758796, Length=127, Percent_Identity=33.8582677165354, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4557537, Length=136, Percent_Identity=31.6176470588235, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI58761500, Length=130, Percent_Identity=31.5384615384615, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1789574, Length=390, Percent_Identity=66.9230769230769, Blast_Score=459, Evalue=1e-130,
Organism=Escherichia coli, GI1787454, Length=128, Percent_Identity=32.8125, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=328, Percent_Identity=39.0243902439024, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=309, Percent_Identity=32.0388349514563, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17509631, Length=131, Percent_Identity=35.8778625954198, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=32.2033898305085, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=165, Percent_Identity=37.5757575757576, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319281, Length=128, Percent_Identity=32.03125, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129375, Length=311, Percent_Identity=36.6559485530547, Blast_Score=157, Evalue=9e-39,
Organism=Drosophila melanogaster, GI24585318, Length=290, Percent_Identity=38.6206896551724, Blast_Score=154, Evalue=8e-38,
Organism=Drosophila melanogaster, GI24640873, Length=100, Percent_Identity=35, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640877, Length=100, Percent_Identity=35, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640875, Length=100, Percent_Identity=35, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_SHEAM (A1S9H3)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_928699.1
- ProteinModelPortal:   A1S9H3
- SMR:   A1S9H3
- STRING:   A1S9H3
- GeneID:   4605074
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_2827
- NMPDR:   fig|326297.7.peg.2648
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   YIQADEN
- PhylomeDB:   A1S9H3
- ProtClustDB:   PRK12298
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 42455; Mature: 42455

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDEAVIKVQAGDGGSGCVSFRREKYIPDGGPDGGDGGDGGSVYLVADASLNTLIDYR
CCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
FERFYLAERGENGRGRDCTGKGGSDLTLRVPVGTRAVDIDTDEVLGDLTEVGQKLLVAKG
HHHEEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHCCC
GFHGLGNTRFKSSVNRAPRQKTLGTKGEVRELRLELLLLADVGLLGMPNAGKSTFIRAVS
CCCCCCCHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHH
RATPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAAEGAGLGIRFLKHLERCRV
HCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHH
LLHILDIEPIDGSSPAESARAIVAELEKYSPELAAKPRWLVFNKTDLLLEEELQERVDAI
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCEEEECCCHHHHHHHHHHHHHHH
VAELGWEGDVYTMSAATREGTKELAEKLFDFIKSLPDEAAAADPDKEVEFKWDNYHKAQL
HHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEECCCCCCCC
DDLNPDFDDSDDDDDFDDDDYDVEVIYQR
CCCCCCCCCCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MKFVDEAVIKVQAGDGGSGCVSFRREKYIPDGGPDGGDGGDGGSVYLVADASLNTLIDYR
CCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
FERFYLAERGENGRGRDCTGKGGSDLTLRVPVGTRAVDIDTDEVLGDLTEVGQKLLVAKG
HHHEEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHCCC
GFHGLGNTRFKSSVNRAPRQKTLGTKGEVRELRLELLLLADVGLLGMPNAGKSTFIRAVS
CCCCCCCHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHH
RATPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAAEGAGLGIRFLKHLERCRV
HCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHH
LLHILDIEPIDGSSPAESARAIVAELEKYSPELAAKPRWLVFNKTDLLLEEELQERVDAI
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCEEEECCCHHHHHHHHHHHHHHH
VAELGWEGDVYTMSAATREGTKELAEKLFDFIKSLPDEAAAADPDKEVEFKWDNYHKAQL
HHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEECCCCCCCC
DDLNPDFDDSDDDDDFDDDDYDVEVIYQR
CCCCCCCCCCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA