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The map label for this gene is pgk [H]

Identifier: 119775889

GI number: 119775889

Start: 3296451

End: 3297632

Strand: Reverse

Name: pgk [H]

Synonym: Sama_2757

Alternate gene names: 119775889

Gene position: 3297632-3296451 (Counterclockwise)

Preceding gene: 119775890

Following gene: 119775888

Centisome position: 76.58

GC content: 58.04

Gene sequence:

>1182_bases
ATGACAATTATCAAAATGTCAGACCTGGATCTTAACGGCAAGCGCGTGCTTATCCGTGAAGATCTGAACGTGCCTGTGGC
CGATGGCGTTGTCACCAGCGACGCCCGTCTGCGCGCCTCTCTGCCCACCATTAAGCTGGCGCTGGAAAAAGGCGCTGCGG
TAATGGTGATGTCTCACCTGGGCCGCCCGACCGAAGGTGAATACAACGAAGAGTTCTCCATGAAGCCTGTGGTGAACTAC
CTGACTGCCGCACTGGATTGCCCTGTGCGTCTGGTCAGCGACTACCTCGATGGCGTTGATGTGGCCGTTGGCGAAGTGGT
GGTGTTCGAAAACGTGCGCTTCAACAAAGGCGAGAAGAAGAACGATGAGGCACTGTCGAAGAAGATGGCAGCCCTGTGTG
ACGTTTACGTGATGGATGCCTTCGGTACCGCACACCGCGCCGAAGCCTCCACCAACGGTGTAGGCCTGTATGCCCCCATC
GCCTGCGCAGGTCCGCTGCTTGCTGCTGAGCTTGATGCTCTCGGTAAGGCGCTGGATAACCCAGCCCGTCCGCTGGTGGC
CATTGTGGGTGGCTCCAAGGTATCAACCAAGCTGACCGTGCTCGAGTCACTTTCCGGCATCGTTGACCAGTTGGTGGTTG
GCGGCGGTATCGCCAACACCTTTATTGCTGCAGCCGGTAATCAGGTAGGCAAGTCGCTGTATGAAGCCGACCTGATTGAT
GAAGCCAAGCGTCTGGTGGCCAATGCCCAAAGCCGCGGCGGCGATATCCCTGTGCCTACCGATGTGGTTGTCGGTAAAGA
GTTCAGCCCAACTGCGGTAGCTACCCTGAAAAACGTCAGCGATGTGGCCGCAGACGATATGATTTTCGATATTGGCCCCG
ACAGTGCCGAGGCCCTGGCCGCCATCCTCAAGAATGCCGGCACCATAGTCTGGAACGGCCCTGTAGGCGTGTTCGAGTTT
GACCAGTTCGGTGAAGGCACCAAGCGCATCGCCCAGGCCATTGCTGAGTCCTCTGCTTTCTCTATCGCCGGTGGTGGCGA
TACTTTGGCGGCCGTGGATAAATACGGTATCGCCGACAAGGTGTCTTACATCTCTACCGGTGGTGGCGCCTTCCTTGAGT
TCCTCGAAGGCAAGGAGCTGCCTGCCGTGGCCATGCTCACCGCCCGTGGCGCCAAGGCTTAA

Upstream 100 bases:

>100_bases
GGCCACACAGGCTGAATGACCCTACAGGATAATGAAGAAGAGCAGGGACAAGCTTTTCTCACAAGAATTTGTTTTTGATT
AAAAATAAGGAAGCAATACC

Downstream 100 bases:

>100_bases
CACAGCAACAAATTACTATTATTAGAAGAAACCGCCTCCCGGGAGACCGGGAGGCATAAAAATCAGTCCAAACGATAGCG
ACCTCGGTGACCCACATTCA

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTIIKMSDLDLNGKRVLIREDLNVPVADGVVTSDARLRASLPTIKLALEKGAAVMVMSHLGRPTEGEYNEEFSMKPVVNY
LTAALDCPVRLVSDYLDGVDVAVGEVVVFENVRFNKGEKKNDEALSKKMAALCDVYVMDAFGTAHRAEASTNGVGLYAPI
ACAGPLLAAELDALGKALDNPARPLVAIVGGSKVSTKLTVLESLSGIVDQLVVGGGIANTFIAAAGNQVGKSLYEADLID
EAKRLVANAQSRGGDIPVPTDVVVGKEFSPTAVATLKNVSDVAADDMIFDIGPDSAEALAAILKNAGTIVWNGPVGVFEF
DQFGEGTKRIAQAIAESSAFSIAGGGDTLAAVDKYGIADKVSYISTGGGAFLEFLEGKELPAVAMLTARGAKA

Sequences:

>Translated_393_residues
MTIIKMSDLDLNGKRVLIREDLNVPVADGVVTSDARLRASLPTIKLALEKGAAVMVMSHLGRPTEGEYNEEFSMKPVVNY
LTAALDCPVRLVSDYLDGVDVAVGEVVVFENVRFNKGEKKNDEALSKKMAALCDVYVMDAFGTAHRAEASTNGVGLYAPI
ACAGPLLAAELDALGKALDNPARPLVAIVGGSKVSTKLTVLESLSGIVDQLVVGGGIANTFIAAAGNQVGKSLYEADLID
EAKRLVANAQSRGGDIPVPTDVVVGKEFSPTAVATLKNVSDVAADDMIFDIGPDSAEALAAILKNAGTIVWNGPVGVFEF
DQFGEGTKRIAQAIAESSAFSIAGGGDTLAAVDKYGIADKVSYISTGGGAFLEFLEGKELPAVAMLTARGAKA
>Mature_392_residues
TIIKMSDLDLNGKRVLIREDLNVPVADGVVTSDARLRASLPTIKLALEKGAAVMVMSHLGRPTEGEYNEEFSMKPVVNYL
TAALDCPVRLVSDYLDGVDVAVGEVVVFENVRFNKGEKKNDEALSKKMAALCDVYVMDAFGTAHRAEASTNGVGLYAPIA
CAGPLLAAELDALGKALDNPARPLVAIVGGSKVSTKLTVLESLSGIVDQLVVGGGIANTFIAAAGNQVGKSLYEADLIDE
AKRLVANAQSRGGDIPVPTDVVVGKEFSPTAVATLKNVSDVAADDMIFDIGPDSAEALAAILKNAGTIVWNGPVGVFEFD
QFGEGTKRIAQAIAESSAFSIAGGGDTLAAVDKYGIADKVSYISTGGGAFLEFLEGKELPAVAMLTARGAKA

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI31543397, Length=412, Percent_Identity=39.3203883495146, Blast_Score=272, Evalue=4e-73,
Organism=Homo sapiens, GI4505763, Length=412, Percent_Identity=38.1067961165049, Blast_Score=263, Evalue=2e-70,
Organism=Escherichia coli, GI1789294, Length=392, Percent_Identity=75.5102040816327, Blast_Score=586, Evalue=1e-169,
Organism=Caenorhabditis elegans, GI17508823, Length=414, Percent_Identity=41.304347826087, Blast_Score=289, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6319857, Length=414, Percent_Identity=41.304347826087, Blast_Score=285, Evalue=8e-78,
Organism=Drosophila melanogaster, GI17136394, Length=412, Percent_Identity=41.0194174757282, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24581203, Length=412, Percent_Identity=38.3495145631068, Blast_Score=253, Evalue=2e-67,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 40821; Mature: 40690

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00111 PGLYCERATE_KINASE ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIIKMSDLDLNGKRVLIREDLNVPVADGVVTSDARLRASLPTIKLALEKGAAVMVMSHL
CEEEEEECCCCCCCEEEEEECCCCCCCCCEEECCCHHEECCCEEEEEHHCCCEEEHHHHC
GRPTEGEYNEEFSMKPVVNYLTAALDCPVRLVSDYLDGVDVAVGEVVVFENVRFNKGEKK
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHCCEEEEECCCCCCCCCC
NDEALSKKMAALCDVYVMDAFGTAHRAEASTNGVGLYAPIACAGPLLAAELDALGKALDN
CHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEHHHHCCHHHHHHHHHHHHHHCC
PARPLVAIVGGSKVSTKLTVLESLSGIVDQLVVGGGIANTFIAAAGNQVGKSLYEADLID
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHH
EAKRLVANAQSRGGDIPVPTDVVVGKEFSPTAVATLKNVSDVAADDMIFDIGPDSAEALA
HHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHH
AILKNAGTIVWNGPVGVFEFDQFGEGTKRIAQAIAESSAFSIAGGGDTLAAVDKYGIADK
HHHHCCCEEEECCCCCEEECHHCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHCCCHHH
VSYISTGGGAFLEFLEGKELPAVAMLTARGAKA
HHHEECCCHHHHHHHCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
TIIKMSDLDLNGKRVLIREDLNVPVADGVVTSDARLRASLPTIKLALEKGAAVMVMSHL
EEEEEECCCCCCCEEEEEECCCCCCCCCEEECCCHHEECCCEEEEEHHCCCEEEHHHHC
GRPTEGEYNEEFSMKPVVNYLTAALDCPVRLVSDYLDGVDVAVGEVVVFENVRFNKGEKK
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHCCEEEEECCCCCCCCCC
NDEALSKKMAALCDVYVMDAFGTAHRAEASTNGVGLYAPIACAGPLLAAELDALGKALDN
CHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEHHHHCCHHHHHHHHHHHHHHCC
PARPLVAIVGGSKVSTKLTVLESLSGIVDQLVVGGGIANTFIAAAGNQVGKSLYEADLID
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHH
EAKRLVANAQSRGGDIPVPTDVVVGKEFSPTAVATLKNVSDVAADDMIFDIGPDSAEALA
HHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHH
AILKNAGTIVWNGPVGVFEFDQFGEGTKRIAQAIAESSAFSIAGGGDTLAAVDKYGIADK
HHHHCCCEEEECCCCCEEECHHCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHCCCHHH
VSYISTGGGAFLEFLEGKELPAVAMLTARGAKA
HHHEECCCHHHHHHHCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA