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The map label for this gene is xerD [H]

Identifier: 119775871

GI number: 119775871

Start: 3272740

End: 3273705

Strand: Reverse

Name: xerD [H]

Synonym: Sama_2739

Alternate gene names: 119775871

Gene position: 3273705-3272740 (Counterclockwise)

Preceding gene: 119775872

Following gene: 119775870

Centisome position: 76.02

GC content: 56.21

Gene sequence:

>966_bases
TTGTCCGCCAAAGCCAATACCTCCCGTAAGGGTGGCAAGCGCCCTGAAAAATCCGGCGCCCCATTGAAACCCAGTGCTGC
CGGTATGGCGTTGATAGATGCATTTTTGGATGAGCTTTGGTCGCTTCAGGGATTGTCTGATAACACCTTAAGTGCCTATC
GTACCGATTTGTGTCAGTTTGATGCCTTTCTCACGGCAAAAGGTATAGGGTTGCTGGCCCTCGATAGTCTCACGCTAAGG
GACTATCTGGCGTACCGTTTTGAACAGGGCATGGCCAAAACCTCGACGGCACGTATGCTCTCAAGCCTGCGCCGCTTCTA
TCGTCATCAACTGGTTTCCGGCACCTTGAGTGAAGACCCAACCGCCCTGATTGAATCGCCCAAACTCCCCAAATCTTTGC
CTGGGAGTCTGTCGGAGGCACAGGTGGAGCAGCTGCTGGCGGAGCCAAGCAGTGACGACCCTGTAGAATGCCGCGATAAA
GCCATGCTCGAGCTCCTGTATGCCACCGGGCTCAGGGTCAGCGAGTTGGTGGGCCTTGGCATGTCGGAGCTGGGGCTGCG
TCAGGGGCTGGTGCGTATTATCGGTAAGGGGGGGAAAGAACGATTGGTGCCCATGGGGGAAGTGGCCCAGGACGCGCTGG
AACAGTTTCTCGCAGGCCCAAGGCAGATGTTGCTTAAGCAGGGCGCCACCGAGGTGGTGTTTCCATCCAATCGTGGCCAG
CAAATGACGCGGCAAACCTTTTGGCACCGCATTAAGCTGTATGCGCTCAGAGCTGGCATTTCCACTGAGCTGTCGCCCCA
CACGTTAAGGCACGCCTTTGCTACTCATTTGTTGAACCACGGCGCCGATCTCAGGGTAGTGCAGCTGCTGCTGGGGCACA
GTTCATTATCGACAACCCAAATCTATACCCATGTGGCCAGAACCCGCCTTGCGGATCTCCATGAAAAACATCACCCCAGG
GGCTGA

Upstream 100 bases:

>100_bases
GCCTCTTTATCGGTAAGCGCGCACCGGCTGCGGCCTGATAGCAATATGCAAGTAAAAGCCGGGTTCGCCCGGCTTTTTTG
TTTTTCCGTTGGAGTCTTTT

Downstream 100 bases:

>100_bases
GAATTTGACTGAAACACCAACTGATACAAATTCAGCCCCGGCTAATTTGCTTTTGTTACCGTTAGACGGTAACTTTTCAG
GCCATTCGCGGGTCTTATAA

Product: integrase/recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSAKANTSRKGGKRPEKSGAPLKPSAAGMALIDAFLDELWSLQGLSDNTLSAYRTDLCQFDAFLTAKGIGLLALDSLTLR
DYLAYRFEQGMAKTSTARMLSSLRRFYRHQLVSGTLSEDPTALIESPKLPKSLPGSLSEAQVEQLLAEPSSDDPVECRDK
AMLELLYATGLRVSELVGLGMSELGLRQGLVRIIGKGGKERLVPMGEVAQDALEQFLAGPRQMLLKQGATEVVFPSNRGQ
QMTRQTFWHRIKLYALRAGISTELSPHTLRHAFATHLLNHGADLRVVQLLLGHSSLSTTQIYTHVARTRLADLHEKHHPR
G

Sequences:

>Translated_321_residues
MSAKANTSRKGGKRPEKSGAPLKPSAAGMALIDAFLDELWSLQGLSDNTLSAYRTDLCQFDAFLTAKGIGLLALDSLTLR
DYLAYRFEQGMAKTSTARMLSSLRRFYRHQLVSGTLSEDPTALIESPKLPKSLPGSLSEAQVEQLLAEPSSDDPVECRDK
AMLELLYATGLRVSELVGLGMSELGLRQGLVRIIGKGGKERLVPMGEVAQDALEQFLAGPRQMLLKQGATEVVFPSNRGQ
QMTRQTFWHRIKLYALRAGISTELSPHTLRHAFATHLLNHGADLRVVQLLLGHSSLSTTQIYTHVARTRLADLHEKHHPR
G
>Mature_320_residues
SAKANTSRKGGKRPEKSGAPLKPSAAGMALIDAFLDELWSLQGLSDNTLSAYRTDLCQFDAFLTAKGIGLLALDSLTLRD
YLAYRFEQGMAKTSTARMLSSLRRFYRHQLVSGTLSEDPTALIESPKLPKSLPGSLSEAQVEQLLAEPSSDDPVECRDKA
MLELLYATGLRVSELVGLGMSELGLRQGLVRIIGKGGKERLVPMGEVAQDALEQFLAGPRQMLLKQGATEVVFPSNRGQQ
MTRQTFWHRIKLYALRAGISTELSPHTLRHAFATHLLNHGADLRVVQLLLGHSSLSTTQIYTHVARTRLADLHEKHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=60.2040816326531, Blast_Score=341, Evalue=3e-95,
Organism=Escherichia coli, GI1790244, Length=278, Percent_Identity=35.6115107913669, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1790768, Length=162, Percent_Identity=32.7160493827161, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790767, Length=168, Percent_Identity=30.952380952381, Blast_Score=78, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35293; Mature: 35162

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKANTSRKGGKRPEKSGAPLKPSAAGMALIDAFLDELWSLQGLSDNTLSAYRTDLCQF
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
DAFLTAKGIGLLALDSLTLRDYLAYRFEQGMAKTSTARMLSSLRRFYRHQLVSGTLSEDP
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TALIESPKLPKSLPGSLSEAQVEQLLAEPSSDDPVECRDKAMLELLYATGLRVSELVGLG
HHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCC
MSELGLRQGLVRIIGKGGKERLVPMGEVAQDALEQFLAGPRQMLLKQGATEVVFPSNRGQ
HHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHCHHHHHHHCCCCEEECCCCCCH
QMTRQTFWHRIKLYALRAGISTELSPHTLRHAFATHLLNHGADLRVVQLLLGHSSLSTTQ
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHH
IYTHVARTRLADLHEKHHPRG
HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SAKANTSRKGGKRPEKSGAPLKPSAAGMALIDAFLDELWSLQGLSDNTLSAYRTDLCQF
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
DAFLTAKGIGLLALDSLTLRDYLAYRFEQGMAKTSTARMLSSLRRFYRHQLVSGTLSEDP
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TALIESPKLPKSLPGSLSEAQVEQLLAEPSSDDPVECRDKAMLELLYATGLRVSELVGLG
HHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCC
MSELGLRQGLVRIIGKGGKERLVPMGEVAQDALEQFLAGPRQMLLKQGATEVVFPSNRGQ
HHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHCHHHHHHHCCCCEEECCCCCCH
QMTRQTFWHRIKLYALRAGISTELSPHTLRHAFATHLLNHGADLRVVQLLLGHSSLSTTQ
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHH
IYTHVARTRLADLHEKHHPRG
HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]