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The map label for this gene is panE [H]

Identifier: 119775691

GI number: 119775691

Start: 3065722

End: 3066624

Strand: Direct

Name: panE [H]

Synonym: Sama_2559

Alternate gene names: 119775691

Gene position: 3065722-3066624 (Clockwise)

Preceding gene: 119775690

Following gene: 119775700

Centisome position: 71.19

GC content: 56.48

Gene sequence:

>903_bases
ATGAGCCGAATTGGCATTCTGGGTGCGGGCGCCGTGGGCCAGTTAATTGCCCATCAGCTGGCGTCGGCGGGCACCTTGCC
CTTTCTGCTGGACCGGCAGCTGACTGCCATTACAGAGCCTTACAGCCTCACAGACCTGAATGGCAATCGCAACACCCTGA
ACTTCGCCAAATCCAACGACAAGCAAGCCCTGCTGGGGGAACTTGATCTTCTTATTATCACAGTGAAGGCCTACCAGGTA
ATTGACGCAGTCACAGGCGCATTGCCCGGTTTATCACCGCACTGCCATCTGCTGTTACTGCACAATGGCCTTGGCCCCCA
CGAAGAGGTGGCGGCCCTGTTGGATGGACGGGGATTGACGCTCGGCACCACCAGTCAGGGAGCGCTGCGGCTTGGCAAAC
ACGACCTTAAACAAACCGGTAGTGGTCTTACGCAATTGGGCCACTGCACAGGTCCGGCCATGGCGCCAGGGCTTAAAACC
TTGCTGCTGAGCGCCATTCCAGGTAGCGAGTGGGTGGAGGCAATTCTGCCCGCCCTGTGGCAAAAACTGGCGGTCAATGC
CTGTATCAATCCCCTTACCGCCATTCACGGCATCTGTAATGGCGAACTGGCAGATAATGCTTACCAAGCTACTATTGCCG
GGGTGCTGAGGGAGCTGGTTGAGGTCGCCAGGACTCAGGGCATTGAGTTACAGGAAGAGAGCTTGTCAGCCCGCGTGTAT
GAGGTCATTCGTCTTACCGCAGCCAATCGCTCATCGATGCGACAGGATGTGGACCATAAGCGCAAAACCGAGATAGATGC
TATAAATGGCTATCTGGTCAGCCTTGGCCATCGCCACAGCATTGCTACACCCACCAACAGAGCTCTGGTCGACGCCATTC
ACACCCTGGAGCGACGCTTTTAA

Upstream 100 bases:

>100_bases
CCTGGGGCGATATCGCAGCCGACCTCGCGGGCGTTGCCGCCTTCTTCCTCACTGCATGGCTGTATAGTAAATACCGCCGC
GCATCCAGGCTTCAGGGCGC

Downstream 100 bases:

>100_bases
ACCACGCACCCTCTTATTGAGGCCACATCACCATGATGGCGGCTAATGCGATAAGAACCAGCGCCGCCATGTCCTTTACC
TGCACCTTTTGCTTCAGATA

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSRIGILGAGAVGQLIAHQLASAGTLPFLLDRQLTAITEPYSLTDLNGNRNTLNFAKSNDKQALLGELDLLIITVKAYQV
IDAVTGALPGLSPHCHLLLLHNGLGPHEEVAALLDGRGLTLGTTSQGALRLGKHDLKQTGSGLTQLGHCTGPAMAPGLKT
LLLSAIPGSEWVEAILPALWQKLAVNACINPLTAIHGICNGELADNAYQATIAGVLRELVEVARTQGIELQEESLSARVY
EVIRLTAANRSSMRQDVDHKRKTEIDAINGYLVSLGHRHSIATPTNRALVDAIHTLERRF

Sequences:

>Translated_300_residues
MSRIGILGAGAVGQLIAHQLASAGTLPFLLDRQLTAITEPYSLTDLNGNRNTLNFAKSNDKQALLGELDLLIITVKAYQV
IDAVTGALPGLSPHCHLLLLHNGLGPHEEVAALLDGRGLTLGTTSQGALRLGKHDLKQTGSGLTQLGHCTGPAMAPGLKT
LLLSAIPGSEWVEAILPALWQKLAVNACINPLTAIHGICNGELADNAYQATIAGVLRELVEVARTQGIELQEESLSARVY
EVIRLTAANRSSMRQDVDHKRKTEIDAINGYLVSLGHRHSIATPTNRALVDAIHTLERRF
>Mature_299_residues
SRIGILGAGAVGQLIAHQLASAGTLPFLLDRQLTAITEPYSLTDLNGNRNTLNFAKSNDKQALLGELDLLIITVKAYQVI
DAVTGALPGLSPHCHLLLLHNGLGPHEEVAALLDGRGLTLGTTSQGALRLGKHDLKQTGSGLTQLGHCTGPAMAPGLKTL
LLSAIPGSEWVEAILPALWQKLAVNACINPLTAIHGICNGELADNAYQATIAGVLRELVEVARTQGIELQEESLSARVYE
VIRLTAANRSSMRQDVDHKRKTEIDAINGYLVSLGHRHSIATPTNRALVDAIHTLERRF

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=307, Percent_Identity=34.2019543973941, Blast_Score=134, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 32014; Mature: 31883

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIGILGAGAVGQLIAHQLASAGTLPFLLDRQLTAITEPYSLTDLNGNRNTLNFAKSND
CCCCCEECCCHHHHHHHHHHHHCCCCHHHHHCHHHHHCCCCEEEECCCCCCEEEECCCCC
KQALLGELDLLIITVKAYQVIDAVTGALPGLSPHCHLLLLHNGLGPHEEVAALLDGRGLT
CHHHHHHHEEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCE
LGTTSQGALRLGKHDLKQTGSGLTQLGHCTGPAMAPGLKTLLLSAIPGSEWVEAILPALW
ECCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHH
QKLAVNACINPLTAIHGICNGELADNAYQATIAGVLRELVEVARTQGIELQEESLSARVY
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
EVIRLTAANRSSMRQDVDHKRKTEIDAINGYLVSLGHRHSIATPTNRALVDAIHTLERRF
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRIGILGAGAVGQLIAHQLASAGTLPFLLDRQLTAITEPYSLTDLNGNRNTLNFAKSND
CCCCEECCCHHHHHHHHHHHHCCCCHHHHHCHHHHHCCCCEEEECCCCCCEEEECCCCC
KQALLGELDLLIITVKAYQVIDAVTGALPGLSPHCHLLLLHNGLGPHEEVAALLDGRGLT
CHHHHHHHEEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCE
LGTTSQGALRLGKHDLKQTGSGLTQLGHCTGPAMAPGLKTLLLSAIPGSEWVEAILPALW
ECCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHH
QKLAVNACINPLTAIHGICNGELADNAYQATIAGVLRELVEVARTQGIELQEESLSARVY
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
EVIRLTAANRSSMRQDVDHKRKTEIDAINGYLVSLGHRHSIATPTNRALVDAIHTLERRF
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]