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The map label for this gene is bioD [H]

Identifier: 119774578

GI number: 119774578

Start: 1751443

End: 1752135

Strand: Direct

Name: bioD [H]

Synonym: Sama_1441

Alternate gene names: 119774578

Gene position: 1751443-1752135 (Clockwise)

Preceding gene: 119774577

Following gene: 119774580

Centisome position: 40.67

GC content: 55.41

Gene sequence:

>693_bases
ATGATGTATTTTGTGACAGGGACCGATACAGACTGTGGTAAGTCTTTTATTTCGGCCGCCTTGCTGTCTGCGGTGACCAA
TCACAAGCCAACAGCCTTAACCCTGGGCATTAAGCCGGTGGCGTCGGGCTGCCGGGTCACAGAATTGGGGCTTAGAAACC
CGGATGCCGAACTGCTGATGGACCACAGCAGTGACAAGCTTGATTATCAGAGCGTCAACCCCATCGCGTTCGAGCCTGCA
ATTGCTCCACATATTGCCGCCGCGAAGGCGGGGGTGGATATAAGCCCGGAAGCCATTATGGCCAAGCTCGATTTGGTCCG
CATGAACTCGGCCGATTTTTGCTTGGTTGAAGGCGCTGGTGGCTGGCGTCTGCCGCTGGGCAATGGACGGTTTATGCCGG
AAATGGTGCAGACACTTGAGTTGCCGGTCGTGCTGGTGGTGGGGATGAAGCTGGGCTGCCTGAACCATGCCATGCTGACT
CAAGAAGCCATTAAAGCTGACGGACTGCGTATTGCCGGCTGGGTTGCCAATCGAATTGACCCTGAAATGGCCTGCTATGA
AGAAAATCTCGCGACGCTCATATCTGTAATGGACGCGCCGTTTCTGGGGGCTGTGCCCTATATGGAGTCGGCTAAACCTG
TCGATGCGGCCGCCTTTATTACGCCGGGTCCCTTGTTGTCAGAACAACGCTGA

Upstream 100 bases:

>100_bases
TGGCGAGGATGGATGACGCCGAACGCCTGAGAACACCTCAGGGCTTGCCACTGAGCTATCAGATTTTGTATGTCAGTGCG
GTAAAGCGAGGAGCAAACCT

Downstream 100 bases:

>100_bases
CTGACGCCAAGGTGTGTTTGATAAGCCAAGCCGCAAAAGTCAGTTAAGCAAGAAATAATAAAGGTCACCGTTAGGCGACC
TTTATTATTTACAGTCGATT

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MMYFVTGTDTDCGKSFISAALLSAVTNHKPTALTLGIKPVASGCRVTELGLRNPDAELLMDHSSDKLDYQSVNPIAFEPA
IAPHIAAAKAGVDISPEAIMAKLDLVRMNSADFCLVEGAGGWRLPLGNGRFMPEMVQTLELPVVLVVGMKLGCLNHAMLT
QEAIKADGLRIAGWVANRIDPEMACYEENLATLISVMDAPFLGAVPYMESAKPVDAAAFITPGPLLSEQR

Sequences:

>Translated_230_residues
MMYFVTGTDTDCGKSFISAALLSAVTNHKPTALTLGIKPVASGCRVTELGLRNPDAELLMDHSSDKLDYQSVNPIAFEPA
IAPHIAAAKAGVDISPEAIMAKLDLVRMNSADFCLVEGAGGWRLPLGNGRFMPEMVQTLELPVVLVVGMKLGCLNHAMLT
QEAIKADGLRIAGWVANRIDPEMACYEENLATLISVMDAPFLGAVPYMESAKPVDAAAFITPGPLLSEQR
>Mature_230_residues
MMYFVTGTDTDCGKSFISAALLSAVTNHKPTALTLGIKPVASGCRVTELGLRNPDAELLMDHSSDKLDYQSVNPIAFEPA
IAPHIAAAKAGVDISPEAIMAKLDLVRMNSADFCLVEGAGGWRLPLGNGRFMPEMVQTLELPVVLVVGMKLGCLNHAMLT
QEAIKADGLRIAGWVANRIDPEMACYEENLATLISVMDAPFLGAVPYMESAKPVDAAAFITPGPLLSEQR

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=215, Percent_Identity=46.046511627907, Blast_Score=174, Evalue=6e-45,
Organism=Escherichia coli, GI87081944, Length=221, Percent_Identity=39.8190045248869, Blast_Score=150, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24514; Mature: 24514

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMYFVTGTDTDCGKSFISAALLSAVTNHKPTALTLGIKPVASGCRVTELGLRNPDAELLM
CEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEECHHHCCCCEEEECCCCCCCHHHEE
DHSSDKLDYQSVNPIAFEPAIAPHIAAAKAGVDISPEAIMAKLDLVRMNSADFCLVEGAG
CCCCCCCCCCCCCCEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHEEECCCCEEEEECCC
GWRLPLGNGRFMPEMVQTLELPVVLVVGMKLGCLNHAMLTQEAIKADGLRIAGWVANRID
CEEEECCCCCCHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCC
PEMACYEENLATLISVMDAPFLGAVPYMESAKPVDAAAFITPGPLLSEQR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MMYFVTGTDTDCGKSFISAALLSAVTNHKPTALTLGIKPVASGCRVTELGLRNPDAELLM
CEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEECHHHCCCCEEEECCCCCCCHHHEE
DHSSDKLDYQSVNPIAFEPAIAPHIAAAKAGVDISPEAIMAKLDLVRMNSADFCLVEGAG
CCCCCCCCCCCCCCEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHEEECCCCEEEEECCC
GWRLPLGNGRFMPEMVQTLELPVVLVVGMKLGCLNHAMLTQEAIKADGLRIAGWVANRID
CEEEECCCCCCHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCC
PEMACYEENLATLISVMDAPFLGAVPYMESAKPVDAAAFITPGPLLSEQR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA