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The map label for this gene is bioC [H]

Identifier: 119774577

GI number: 119774577

Start: 1750700

End: 1751446

Strand: Direct

Name: bioC [H]

Synonym: Sama_1440

Alternate gene names: 119774577

Gene position: 1750700-1751446 (Clockwise)

Preceding gene: 119774576

Following gene: 119774578

Centisome position: 40.66

GC content: 54.75

Gene sequence:

>747_bases
ATGACGACCCAATACGATGTGGCAGAGCACTTTTCCCGCGCTCATCAGTACGATTGCCACAACCTGCTGCAGCGATTAAC
CGCAAATAAACTGTTGACCAAGGCAGCGCTTGGGGGCCATTTACTGGATATTGGCGCAGGCCCGGGGACCGATTTTTCGC
TGTTCCCAGTCATTCGGGTGACTACGGTGGATATTGCGTTCGCCATGTGTCAAAGGCTTAAAAGTCTTCATCACTCCTAT
GAGGCTGTGTGCGCCGATGCTGCCGCCTTGCCTTTTTCCAATGCGTGCTTCGATAGTCTCTATTCCAATCTTGCGCTGCA
ATGGTGCCCCGACTTTACCGTGGCGGTTGCTGAGGCGTCTCGGGTGCTTAAACCCGGTGGTCGTGGCCACTTTGCCATGG
TGTGCGACGGCGCATTGCCAGAGCTTGAAGCAATGGGTTTTTGTGTGAATCATTTTGCGCCGGCATCCATGATGGCAGCG
GCCTTCAGCGACCAGGACTGGTGCGAATTATCCATCGATGTGGTGACAGAAACCCTCTATTTTGATGATTTGCGGACACT
GCTTTATTCCATCAAAGGGGTTGGTGCCAGTGCCCGCCACGGTGCCGGGCAGGGCAAGGCATTGCGTGGCCGAACCGACT
GGCTGGCGAGGATGGATGACGCCGAACGCCTGAGAACACCTCAGGGCTTGCCACTGAGCTATCAGATTTTGTATGTCAGT
GCGGTAAAGCGAGGAGCAAACCTATGA

Upstream 100 bases:

>100_bases
GCATGAACAGTATAGAGGCATTGGTAAACGCTCTGGCGGACATTGAAAAAGGCTTTGGCGAGGGCGTTAACGAATGCGTA
GTCAAAGGCAGTGATAAGCC

Downstream 100 bases:

>100_bases
TGTATTTTGTGACAGGGACCGATACAGACTGTGGTAAGTCTTTTATTTCGGCCGCCTTGCTGTCTGCGGTGACCAATCAC
AAGCCAACAGCCTTAACCCT

Product: biotin synthesis protein BioC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTTQYDVAEHFSRAHQYDCHNLLQRLTANKLLTKAALGGHLLDIGAGPGTDFSLFPVIRVTTVDIAFAMCQRLKSLHHSY
EAVCADAAALPFSNACFDSLYSNLALQWCPDFTVAVAEASRVLKPGGRGHFAMVCDGALPELEAMGFCVNHFAPASMMAA
AFSDQDWCELSIDVVTETLYFDDLRTLLYSIKGVGASARHGAGQGKALRGRTDWLARMDDAERLRTPQGLPLSYQILYVS
AVKRGANL

Sequences:

>Translated_248_residues
MTTQYDVAEHFSRAHQYDCHNLLQRLTANKLLTKAALGGHLLDIGAGPGTDFSLFPVIRVTTVDIAFAMCQRLKSLHHSY
EAVCADAAALPFSNACFDSLYSNLALQWCPDFTVAVAEASRVLKPGGRGHFAMVCDGALPELEAMGFCVNHFAPASMMAA
AFSDQDWCELSIDVVTETLYFDDLRTLLYSIKGVGASARHGAGQGKALRGRTDWLARMDDAERLRTPQGLPLSYQILYVS
AVKRGANL
>Mature_247_residues
TTQYDVAEHFSRAHQYDCHNLLQRLTANKLLTKAALGGHLLDIGAGPGTDFSLFPVIRVTTVDIAFAMCQRLKSLHHSYE
AVCADAAALPFSNACFDSLYSNLALQWCPDFTVAVAEASRVLKPGGRGHFAMVCDGALPELEAMGFCVNHFAPASMMAAA
FSDQDWCELSIDVVTETLYFDDLRTLLYSIKGVGASARHGAGQGKALRGRTDWLARMDDAERLRTPQGLPLSYQILYVSA
VKRGANL

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786994, Length=194, Percent_Identity=30.4123711340206, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 27036; Mature: 26905

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQYDVAEHFSRAHQYDCHNLLQRLTANKLLTKAALGGHLLDIGAGPGTDFSLFPVIRV
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHH
TTVDIAFAMCQRLKSLHHSYEAVCADAAALPFSNACFDSLYSNLALQWCPDFTVAVAEAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
RVLKPGGRGHFAMVCDGALPELEAMGFCVNHFAPASMMAAAFSDQDWCELSIDVVTETLY
HHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCHHEEHHHHHHHHHH
FDDLRTLLYSIKGVGASARHGAGQGKALRGRTDWLARMDDAERLRTPQGLPLSYQILYVS
HHHHHHHHHHHHCCCCCCCCCCCCCCEECCHHHHHHHCCCHHHHCCCCCCCCEEHHHHHH
AVKRGANL
HHHHCCCC
>Mature Secondary Structure 
TTQYDVAEHFSRAHQYDCHNLLQRLTANKLLTKAALGGHLLDIGAGPGTDFSLFPVIRV
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHH
TTVDIAFAMCQRLKSLHHSYEAVCADAAALPFSNACFDSLYSNLALQWCPDFTVAVAEAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
RVLKPGGRGHFAMVCDGALPELEAMGFCVNHFAPASMMAAAFSDQDWCELSIDVVTETLY
HHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCHHEEHHHHHHHHHH
FDDLRTLLYSIKGVGASARHGAGQGKALRGRTDWLARMDDAERLRTPQGLPLSYQILYVS
HHHHHHHHHHHHCCCCCCCCCCCCCCEECCHHHHHHHCCCHHHHCCCCCCCCEEHHHHHH
AVKRGANL
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9063571 [H]