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The map label for this gene is gsk [H]

Identifier: 119774454

GI number: 119774454

Start: 1601151

End: 1602455

Strand: Direct

Name: gsk [H]

Synonym: Sama_1317

Alternate gene names: 119774454

Gene position: 1601151-1602455 (Clockwise)

Preceding gene: 119774453

Following gene: 119774455

Centisome position: 37.18

GC content: 53.64

Gene sequence:

>1305_bases
ATGAAGTTTCCTGGCCAGCGCAAGTCAAAACATTACTTCCCCGTGAATACCCGAGATCCGCTGCTTGAGCAGTTGACTCA
GCAACCTCAGCCAAAGCAGACCTATATCAGTGGTATTGACCAGACCCTGGTGGACATTGAAGCCAAGGTCGCCGAAGACT
TGTTGGTGCGTTATCAGTTGCCAAAAGGTAATTCCACCCTGATTGATGACGCCACCGCCCACGCGCTCTATGAGGAGCTC
AAGCGTGATAACCTTATCAGCGACGAGTTTGCCGGTGGCACTATTGGTAACACAGTACACAACTACTCTATTTTGGCTGA
TGATCGCTCAGTGCTGTTTGGGGTAATGAGCAAGTCTATCGAAGTGGGCAGCTACGCCTATCGTTACCTCTGCCACACCT
CATCCAAGGTCGATTTGAATCACTTGCAGCCGGTAGACGGGCCTATTGGCCGCTGTTTTACCCTGATTTCAGATTGCGGT
GAGCGTACCTTTGCCATCAGCAAAGGCGCCATGGACAAGCTGACGCCGGACTTTATCGATAAGGATGTGGTGCAGGGCAG
TGCGGCGCTGGTACTGACGGCCTACCTGATGCGGGCGGCCGAAGGTGATGGCATGAGCCAGGCAGCACTCAAAGCCATCG
AATACGCCAAGGCAGCCGATGTCCCAGTGGTGCTGACTCTCGGTACCCGCTTTCTTATTCAGGAAGATCCAGAGTGGTGG
CAGGGCTTTATTCGTGACAACGTCACCATATTGGCGATGAACGAAGATGAAGGTGAAGCCCTGACGGGCTTTGCCGATCC
CCTCCTTGCCAGTGAGGCTGCGCTGGAGTGGTGTGACATGGTGCTGACAACGGCGGGTCCCATAGGTCTTTATACTGCAG
GTTACACCGAAGACAGTGACAAGCGTGAAACCAGCCATACGCTGCTGCCTGGTGCGATTCCCGAGTTCAACCGCTTTGAG
TTTTCCCGTCCGATGCGTAAGCGTGATTGCCGAGAGCCCATAAAGGTGTATGCGCATATTTCGCCCTATATGGGAGGCCC
GGAACAAATCCGCAATACCAATGGCGCTGGTGATGGTGCACTGTCAGCACTGCTCCATGACCTGGCGGCGAATAATTTCC
ACAAGGTTAATGTTCCCGGCTCCAGTAAACACAGAAACGAAGGCCTCTGCTATTCGTCATTCTCACAAATCTGCAAGTAC
GCCAACCGTGTTGCCTATGAAGTGCTGGCGCAGCACAGCCCGCGTTTATCCAGAGCTTTGCCGGAGCGGGAAGACAGCCT
GGAAGAGTCTTATTGGGAGCGTTAA

Upstream 100 bases:

>100_bases
TTAAGTGCGGTGCCAGGCATGGCTCCGGACCATGACCTGCATGGATGCGGCAAGTGCAACTCTGCCATAGTGCAAATAGG
CAAAGAACAGAGATCCCGTT

Downstream 100 bases:

>100_bases
TCCCAGAGCCCTGCCGTAGAAGAGATTTTACCGGGTGGGGTAGATAAATAGACAGAGATAAAAAAAGGCGCCATCGGCGC
CTTTTTTATTGTCACTCTAA

Product: inosine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKFPGQRKSKHYFPVNTRDPLLEQLTQQPQPKQTYISGIDQTLVDIEAKVAEDLLVRYQLPKGNSTLIDDATAHALYEEL
KRDNLISDEFAGGTIGNTVHNYSILADDRSVLFGVMSKSIEVGSYAYRYLCHTSSKVDLNHLQPVDGPIGRCFTLISDCG
ERTFAISKGAMDKLTPDFIDKDVVQGSAALVLTAYLMRAAEGDGMSQAALKAIEYAKAADVPVVLTLGTRFLIQEDPEWW
QGFIRDNVTILAMNEDEGEALTGFADPLLASEAALEWCDMVLTTAGPIGLYTAGYTEDSDKRETSHTLLPGAIPEFNRFE
FSRPMRKRDCREPIKVYAHISPYMGGPEQIRNTNGAGDGALSALLHDLAANNFHKVNVPGSSKHRNEGLCYSSFSQICKY
ANRVAYEVLAQHSPRLSRALPEREDSLEESYWER

Sequences:

>Translated_434_residues
MKFPGQRKSKHYFPVNTRDPLLEQLTQQPQPKQTYISGIDQTLVDIEAKVAEDLLVRYQLPKGNSTLIDDATAHALYEEL
KRDNLISDEFAGGTIGNTVHNYSILADDRSVLFGVMSKSIEVGSYAYRYLCHTSSKVDLNHLQPVDGPIGRCFTLISDCG
ERTFAISKGAMDKLTPDFIDKDVVQGSAALVLTAYLMRAAEGDGMSQAALKAIEYAKAADVPVVLTLGTRFLIQEDPEWW
QGFIRDNVTILAMNEDEGEALTGFADPLLASEAALEWCDMVLTTAGPIGLYTAGYTEDSDKRETSHTLLPGAIPEFNRFE
FSRPMRKRDCREPIKVYAHISPYMGGPEQIRNTNGAGDGALSALLHDLAANNFHKVNVPGSSKHRNEGLCYSSFSQICKY
ANRVAYEVLAQHSPRLSRALPEREDSLEESYWER
>Mature_434_residues
MKFPGQRKSKHYFPVNTRDPLLEQLTQQPQPKQTYISGIDQTLVDIEAKVAEDLLVRYQLPKGNSTLIDDATAHALYEEL
KRDNLISDEFAGGTIGNTVHNYSILADDRSVLFGVMSKSIEVGSYAYRYLCHTSSKVDLNHLQPVDGPIGRCFTLISDCG
ERTFAISKGAMDKLTPDFIDKDVVQGSAALVLTAYLMRAAEGDGMSQAALKAIEYAKAADVPVVLTLGTRFLIQEDPEWW
QGFIRDNVTILAMNEDEGEALTGFADPLLASEAALEWCDMVLTTAGPIGLYTAGYTEDSDKRETSHTLLPGAIPEFNRFE
FSRPMRKRDCREPIKVYAHISPYMGGPEQIRNTNGAGDGALSALLHDLAANNFHKVNVPGSSKHRNEGLCYSSFSQICKY
ANRVAYEVLAQHSPRLSRALPEREDSLEESYWER

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1786684, Length=434, Percent_Identity=67.0506912442396, Blast_Score=635, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.73 [H]

Molecular weight: Translated: 48199; Mature: 48199

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFPGQRKSKHYFPVNTRDPLLEQLTQQPQPKQTYISGIDQTLVDIEAKVAEDLLVRYQL
CCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
PKGNSTLIDDATAHALYEELKRDNLISDEFAGGTIGNTVHNYSILADDRSVLFGVMSKSI
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHCEEEEECCHHHHHHHHHHHH
EVGSYAYRYLCHTSSKVDLNHLQPVDGPIGRCFTLISDCGERTFAISKGAMDKLTPDFID
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCHHHCCHHHHH
KDVVQGSAALVLTAYLMRAAEGDGMSQAALKAIEYAKAADVPVVLTLGTRFLIQEDPEWW
HHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCHHHH
QGFIRDNVTILAMNEDEGEALTGFADPLLASEAALEWCDMVLTTAGPIGLYTAGYTEDSD
HHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCC
KRETSHTLLPGAIPEFNRFEFSRPMRKRDCREPIKVYAHISPYMGGPEQIRNTNGAGDGA
CHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHEEECCCCCCHHHHCCCCCCCHHH
LSALLHDLAANNFHKVNVPGSSKHRNEGLCYSSFSQICKYANRVAYEVLAQHSPRLSRAL
HHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
PEREDSLEESYWER
CCHHHHHHHHHCCC
>Mature Secondary Structure
MKFPGQRKSKHYFPVNTRDPLLEQLTQQPQPKQTYISGIDQTLVDIEAKVAEDLLVRYQL
CCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
PKGNSTLIDDATAHALYEELKRDNLISDEFAGGTIGNTVHNYSILADDRSVLFGVMSKSI
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHCEEEEECCHHHHHHHHHHHH
EVGSYAYRYLCHTSSKVDLNHLQPVDGPIGRCFTLISDCGERTFAISKGAMDKLTPDFID
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCHHHCCHHHHH
KDVVQGSAALVLTAYLMRAAEGDGMSQAALKAIEYAKAADVPVVLTLGTRFLIQEDPEWW
HHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCHHHH
QGFIRDNVTILAMNEDEGEALTGFADPLLASEAALEWCDMVLTTAGPIGLYTAGYTEDSD
HHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCC
KRETSHTLLPGAIPEFNRFEFSRPMRKRDCREPIKVYAHISPYMGGPEQIRNTNGAGDGA
CHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHEEECCCCCCHHHHCCCCCCCHHH
LSALLHDLAANNFHKVNVPGSSKHRNEGLCYSSFSQICKYANRVAYEVLAQHSPRLSRAL
HHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
PEREDSLEESYWER
CCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]