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The map label for this gene is torC [H]

Identifier: 119774125

GI number: 119774125

Start: 1196523

End: 1197698

Strand: Reverse

Name: torC [H]

Synonym: Sama_0988

Alternate gene names: 119774125

Gene position: 1197698-1196523 (Counterclockwise)

Preceding gene: 119774126

Following gene: 119774124

Centisome position: 27.81

GC content: 56.97

Gene sequence:

>1176_bases
ATGAAATGGTTCTCTTCTCTCAGACAAACCCTCGGCAAGCCCGCACTCTCCCTGAGTCTGGGCTTTATTGCCATCAGCGC
CTTTATCATGGGTATTGTGTTCTGGGGCGGCTTTAACACCGCGCTGGAAGCCACCAATACCGAAGAGTTTTGTATCAGCT
GCCACAGCATGGAAAGCAAGCCCTATCAGGAGCTGCAGCAGACTGTGCATTGGTCAAATCACTCTGGCGTGCGTGCCACC
TGCCCCGACTGCCACGTGCCCCACGACTGGAGCCGCAAAATCGCCCGCAAGATGGAGGCCTCCCACGACGTATGGGGCTG
GCTGTTCCAGACCGTGAATACCGACGAGAAATTCGAAGCCAAGCGTCTTGAGATGGCGAGCCGCGAGTGGAAACGCTTCG
ATAGAGACAACAGCCTTGCCTGTAAAAACTGCCACGATTACCAGTCGATGAAGTGGGACACCATGTCGCCGCTGGCGCAA
AAACAGATGAAGCGCGCCGCCGAAATTGACCAGTCCTGCATCGATTGTCACAAGGGCATTGCCCACAAGCTGCCGGACAT
GGGCACAGCCCGCGCCCCTGAGCTGATTGCCGAGGTAGGCAGCGGCGTAACCCCCAATGTAGGCGAGAGCTACTTCAGCG
CCCTGACCAAGCCATTGTATCTGGATGCCACCACCGCCGAAGAAGCGGGCACTTTGAACGTGGCCACCAAGGTCAAGGTA
CTGGAAACCAGCGGCAAGCGCGTAAAAGTGGCCATTGAAGGCTGGCGCAAGCGTGTGGGTGCAGGCCGGGTGATCTACTT
CGACTTTGGGGTGAATATCCTCTCGGCTCAGCTGTCACTGGATGCCGCCAAAACCCCTGACCTTATCCGTACCTTTGAAG
AAAAACAGGACCCCATGACGGGTCTCATGTGGGAGCGAATTGAAGCCGACATCTGGACCGATGCCGACTACCTGCTTGGT
GACATAGCCCCGCTATGGAGCTACGCCAAAACCACCTACAGCAGCAGCTGCAGCGTATGCCACACCCAGCCAGAGGAAGC
CCACTTCGATGCCAACACCTGGCCGGGCATGTTCCAGGGCATGTTGGCCTTCGTCAACATGGATCAGGACACCCAGGCGC
TGGTACAGAAGTACCTGCAGGAACACTCAGCCACCTTTAACAAAGATGCCCACTAA

Upstream 100 bases:

>100_bases
TGCACTTACCGTCACCTTTATCAGCCTCTACGGTTTGGCGCTCTGGGTTTACCAGGCCGTCACCGGCGTTGCGCCCCACT
GATTTTCGAGGATATTGCAT

Downstream 100 bases:

>100_bases
GGGGAGACAGTCAGATGAAAAGACGTGATTTTTTAAAAGGCCTGATGTCAGCCTCCTGTATGGCCATAGGCTCCACCAGC
CTGCTGAGCCCATTGAACGC

Product: tetraheme cytochrome c

Products: H2O; trimethylamine; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MKWFSSLRQTLGKPALSLSLGFIAISAFIMGIVFWGGFNTALEATNTEEFCISCHSMESKPYQELQQTVHWSNHSGVRAT
CPDCHVPHDWSRKIARKMEASHDVWGWLFQTVNTDEKFEAKRLEMASREWKRFDRDNSLACKNCHDYQSMKWDTMSPLAQ
KQMKRAAEIDQSCIDCHKGIAHKLPDMGTARAPELIAEVGSGVTPNVGESYFSALTKPLYLDATTAEEAGTLNVATKVKV
LETSGKRVKVAIEGWRKRVGAGRVIYFDFGVNILSAQLSLDAAKTPDLIRTFEEKQDPMTGLMWERIEADIWTDADYLLG
DIAPLWSYAKTTYSSSCSVCHTQPEEAHFDANTWPGMFQGMLAFVNMDQDTQALVQKYLQEHSATFNKDAH

Sequences:

>Translated_391_residues
MKWFSSLRQTLGKPALSLSLGFIAISAFIMGIVFWGGFNTALEATNTEEFCISCHSMESKPYQELQQTVHWSNHSGVRAT
CPDCHVPHDWSRKIARKMEASHDVWGWLFQTVNTDEKFEAKRLEMASREWKRFDRDNSLACKNCHDYQSMKWDTMSPLAQ
KQMKRAAEIDQSCIDCHKGIAHKLPDMGTARAPELIAEVGSGVTPNVGESYFSALTKPLYLDATTAEEAGTLNVATKVKV
LETSGKRVKVAIEGWRKRVGAGRVIYFDFGVNILSAQLSLDAAKTPDLIRTFEEKQDPMTGLMWERIEADIWTDADYLLG
DIAPLWSYAKTTYSSSCSVCHTQPEEAHFDANTWPGMFQGMLAFVNMDQDTQALVQKYLQEHSATFNKDAH
>Mature_391_residues
MKWFSSLRQTLGKPALSLSLGFIAISAFIMGIVFWGGFNTALEATNTEEFCISCHSMESKPYQELQQTVHWSNHSGVRAT
CPDCHVPHDWSRKIARKMEASHDVWGWLFQTVNTDEKFEAKRLEMASREWKRFDRDNSLACKNCHDYQSMKWDTMSPLAQ
KQMKRAAEIDQSCIDCHKGIAHKLPDMGTARAPELIAEVGSGVTPNVGESYFSALTKPLYLDATTAEEAGTLNVATKVKV
LETSGKRVKVAIEGWRKRVGAGRVIYFDFGVNILSAQLSLDAAKTPDLIRTFEEKQDPMTGLMWERIEADIWTDADYLLG
DIAPLWSYAKTTYSSSCSVCHTQPEEAHFDANTWPGMFQGMLAFVNMDQDTQALVQKYLQEHSATFNKDAH

Specific function: Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorA. Acts by transferring electrons from the membranous menaquinones to TorA. This transfer probably involves an electron transfer pathway from menaquinones to the N-terminal dom

COG id: COG3005

COG function: function code C; Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TorC/TorY family [H]

Homologues:

Organism=Escherichia coli, GI1787230, Length=385, Percent_Identity=37.6623376623377, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI1788530, Length=170, Percent_Identity=53.5294117647059, Blast_Score=208, Evalue=5e-55,
Organism=Escherichia coli, GI1788181, Length=342, Percent_Identity=33.0409356725146, Blast_Score=182, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009154
- InterPro:   IPR011031
- InterPro:   IPR005126 [H]

Pfam domain/function: PF03264 Cytochrom_NNT [H]

EC number: NA

Molecular weight: Translated: 44060; Mature: 44060

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS51008 MULTIHEME_CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWFSSLRQTLGKPALSLSLGFIAISAFIMGIVFWGGFNTALEATNTEEFCISCHSMESK
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHCCCC
PYQELQQTVHWSNHSGVRATCPDCHVPHDWSRKIARKMEASHDVWGWLFQTVNTDEKFEA
HHHHHHHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHH
KRLEMASREWKRFDRDNSLACKNCHDYQSMKWDTMSPLAQKQMKRAAEIDQSCIDCHKGI
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AHKLPDMGTARAPELIAEVGSGVTPNVGESYFSALTKPLYLDATTAEEAGTLNVATKVKV
HHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEECCCCCCCCCEEHHEEEEE
LETSGKRVKVAIEGWRKRVGAGRVIYFDFGVNILSAQLSLDAAKTPDLIRTFEEKQDPMT
EECCCCEEEEEHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHCCCHH
GLMWERIEADIWTDADYLLGDIAPLWSYAKTTYSSSCSVCHTQPEEAHFDANTWPGMFQG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCHHHHH
MLAFVNMDQDTQALVQKYLQEHSATFNKDAH
HHHHHCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKWFSSLRQTLGKPALSLSLGFIAISAFIMGIVFWGGFNTALEATNTEEFCISCHSMESK
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHCCCC
PYQELQQTVHWSNHSGVRATCPDCHVPHDWSRKIARKMEASHDVWGWLFQTVNTDEKFEA
HHHHHHHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHH
KRLEMASREWKRFDRDNSLACKNCHDYQSMKWDTMSPLAQKQMKRAAEIDQSCIDCHKGI
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AHKLPDMGTARAPELIAEVGSGVTPNVGESYFSALTKPLYLDATTAEEAGTLNVATKVKV
HHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEECCCCCCCCCEEHHEEEEE
LETSGKRVKVAIEGWRKRVGAGRVIYFDFGVNILSAQLSLDAAKTPDLIRTFEEKQDPMT
EECCCCEEEEEHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHCCCHH
GLMWERIEADIWTDADYLLGDIAPLWSYAKTTYSSSCSVCHTQPEEAHFDANTWPGMFQG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCHHHHH
MLAFVNMDQDTQALVQKYLQEHSATFNKDAH
HHHHHCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trimethylamine-N-oxide; NADH [C]

Specific reaction: trimethylamine-N-oxide + NADH = H2O + trimethylamine + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]