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The map label for this gene is metH [H]

Identifier: 119773895

GI number: 119773895

Start: 938190

End: 941930

Strand: Reverse

Name: metH [H]

Synonym: Sama_0758

Alternate gene names: 119773895

Gene position: 941930-938190 (Counterclockwise)

Preceding gene: 119773905

Following gene: 119773894

Centisome position: 21.87

GC content: 57.87

Gene sequence:

>3741_bases
ATGGCAACTCCAGTGTTATCCCAGGCGACCAAGGCGCTTGCCCAGAGCCGTCAACAGCGACTGAACGAGGATCTCTCCAC
CCGCATTCTTATCCTCGACGGCGCCATGGGAACCATGATCCAGGGCCACAAACTGGAGGAAGAACACTACCGCGGCAGCC
GCTTTGCCGACTGGCACTGCGACGTTAAAGGCAATAACGACCTCCTGGTACTCACCCAGCCAGAGATAATCAAGGGCATC
CACCGCGAGTATCTGCTGGCCGGTGCCGATATCATCGAAACCAACACCTTTAACGCCACCACTGTGGCCATGGCCGACTA
CGACATGCAGTCGCTCTCGGCCGAGATAAACCTTGTTGGTGCCCGCATCGCCCGTGAAGTGGCCGATGAAGTGGAGGCCC
AAACCGGCATCCCCCGCTATGTGGCCGGGGTACTTGGCCCCACCAACCGCACCTGCTCCATCAGCCCGGATGTGAATGAC
CCGGGCTACCGCAATATCCACTTCGATGATCTGGTAACCGCCTACCGCGAGTCCACCGCAGCCCTGATTGAAGGCGGCGC
CGATATCATCATGGTGGAAACCATTTTCGATACCCTGAACGCCAAGGCGGCGCTGTTTGCCATCGAATCCATCTTCGATG
AGGTTGGTCTGCGCCTGCCGGTGATGATTTCCGGCACCATTACCGATGCCTCCGGCCGCACCCTGACCGGCCAGACCACC
GAAGCCTTTTACAATTCGCTGCGCCATATCAAGCCCATCAGCATGGGCCTTAACTGTGCCCTGGGGCCAAAAGAACTGCG
CCCCTACGTGGAAGAACTCTCGCGCATCAGCGAATGCTATGTGTCGGCCCACCCCAACGCCGGTCTGCCGAACGAGTTCG
GTGGCTACGATGAAACGCCAAAAGAAATGGCCGACATCATAGTGCAGTGGGCCATCGAAGGCATGCTCAACATAGTCGGC
GGCTGCTGCGGCACCACCCCGGACCATATCCGGGTTATCCGCGAAGCCGTTGAAAAGCACGCGCCGCGCAAGCTGCCTGA
GCTGCCGGTGGCCTGCCGTCTGGCTGGGCTTGAACCGCTCACCATCAGTGCCGACAGTCTCTTTGTAAACGTGGGTGAGC
GCACCAACGTCACTGGCTCAGCCAAATTCCTGAAGCTGATTAAAGAAGGCCAATACGAGACCGCGCTGGATGTGGCCCGG
GATCAGGTGGAAAACGGCGCCCAAATCATCGACATCAACATGGATGAGGGCATGCTGGACGGCGAAGAGGTGATGACCAC
CTTTTTGAATCTGGTCGCCTCCGAGCCTGAAATCAGCAAGGTGCCCATCATGATTGACTCCTCCAAGTGGGAAGTCATCG
AGGCAGGCCTTAAGTGCGTGCAGGGCAAGTGCATCGTTAACTCCATCTCCCTCAAAGAAGGTGAAGCCAAGTTTATCGAG
CAGGCCACCCTTGTGAAGCGCTACGGCGCCGCCGCCATCATCATGGCCTTCGATGAAACCGGCCAGGCCGACACCCGCGC
CCGTAAAATTGAAATCTGTACCCGCGCCTACCGCATTCTGGTCGATAAAGTCGGCTTCCCGCCGGAAGACATTATCTTCG
ACCCCAACATTTTTGCCGTGGCTACCGGCATCGAAGAGCACGACAACTACGCGGTGGACTTTATCGAGGCGGTGCGCGAC
ATCAAGGCCACCCTGCCCCATGCGATGATTTCCGGCGGCGTGTCCAACGTGTCCTTCTCGTTCCGTGGCAACAACCCGGT
GCGCGAGGCCATCCACGCCGTGTTCCTCTACCATGCCATCAAAGAAGGCATGGACATGGGCATTGTGAATGCGGGGCAAC
TGGCGATTTACGATGACATTCCGGCCGAGCTTAAAGAGCGGGTCGAGGCCGTGGTGCTTAACCTGCCCTGCCCGGTGGAA
GACTCTACCAACACAGAGCAACTGCTTGAGATTGCTGAAAAGTATCGCGGCGGAGGTGGCAGCGGCGCCGGTAAAAAAGA
AGATTTGCAGTGGCGCAGCCTGCCGGTGAACAAGCGCCTTGAGCATGCGCTGGTAAAAGGCATTACCGAATTTATCGACG
CCGACACCGAAGAGGCCCGTCAGCAGGCCACCCGTCCGCTGGATGTGATTGAAGGCCCGCTGATGGACGGCATGAACGTG
GTGGGCGATCTCTTTGGCGAGGGCAAGATGTTCCTGCCCCAGGTGGTTAAATCCGCCCGGGTGATGAAAAAGGCCGTGGC
CTACTTAAACCCCTTTATCGAGGCCGAAAAGGTCGCCGGCCAGAGCAACGGCAAGGTGCTGATGGTCACGGTAAAAGGCG
ACGTGCACGACATCGGCAAAAACATTGTTGGCGTGGTGCTCGCCTGTAACGGCTATGAGGTGATTGACCTGGGCGTTATG
GTGCCGGTGGAGAAAATCGTCGAAGTCGCCAAAAAAGAGCAGGTCGACATTATCGGCATGTCGGGGCTCATTACCCCAAG
CCTCGATGAAATGGTGCATAACGTCAAAACCTTCGAGCGTGAAGGCCTGACCTTGCCCGCCATTATCGGCGGCGCCACCT
GCTCGAAAATCCATACCGCGGTCAAGATTGCGCCCCACTACCCCCACGGCGCGATTTATATTCCCGATGCGTCCCGCGCC
GTGCCCATGGTGAGCAAGCTTATCAACGAAGAGACCCGCGCCGCTACCATCAAGGCCACCTACGATGAATACGATGTGAT
GCGCGAAAAACGCCTGTCACAGGCCAAGCGCAAAGAGATAATCTCCATCGAGGCGGCGCGTGAAAACCGCTGCCAGCTCG
ACTGGGCCAACTACCAGCCCAAGGTGCCGAATAAGCTGGGTATTCAGGTGTTTGAAGACTACCCGCTGGATGATTTGGTC
GATCGCATCGACTGGACACCGTTTTTCCGCGCCTGGGAACTGCACGGCCACTTCCCGCGCATTCTCGAAGACGAAGTGGT
AGGCGAAGAAGCCCGTAAACTCTTTGCCGATGCCAAGGCCATGCTGCAAACCATCATCGATGAAAAGTGGCTCACCGCCA
AAGGCGTGATTGGCCTGTTCCCGGCCAATACCGTAAACCATGACGATATCGAGCTTTACACTGACGAGAGCCGCTCCCAA
GTACTGATGACCACCCATCATTTGCGGATGCAAATCGAGCGGGTGGGCAACGATAACTTCTGTCTGTCGGACTTTGTTGC
CCCCAAAGACAGTGGTGTGGTCGACTACACAGGCGGCTTTGCGGTGTGCGCAGGCCACGGCATCGATGAGCATCTGGCAC
GCTTCGAAGCCAACCACGACGACTACAACGCCATCATGCTCAAGGTACTGGCCGACCGTCTGGCCGAGGCCTTCGCCGAG
CGCATGCATGAGCGGGTACGTAAAGAGTTCTGGGGTTACGCAAGCGATGAAAACCTCGACAACGAGGCGCTTATCCGCGA
GAAATACCGCGGCATCCGCCCCGCCCCCGGCTACCCCGCCTGCCCGGATCACACCGAGAAGGGGCTCTTGTGGGATTTGC
TCAAGCCCAACGAGTGCATTGACCTTAATATCACCGAAAGCTTTGCCATGTACCCCACAGCGGCCGTCAGCGGCTGGTAC
TTCGCCCACCCCGAGGCACGCTACTTTGGCGTGACTAATATCGGCAGGGATCAGGTGGAAGACTACGCCCGTCGTAAGGG
GATGACGGTTGCTGAAACGGAGAAGTGGCTGGCACCGATTTTGGATTACGATCCTGAGTAA

Upstream 100 bases:

>100_bases
TCAAATTAAGCGGGCGCCGTTCCGGTTTTACCTTTCCAGCGGCATCAACCCGGCTTAGGCTACACAGGACAGTCACTTTT
TGTACTTTGCAGGTGTTTTT

Downstream 100 bases:

>100_bases
TCAGGGGAAGCCATACGCCCACCCGGTGTCAGGTCGGTCTGAGGCCGACGGTCACGATTGGGAATGGCCAGAGCTTGGTG
CTAATTTAAGACACCGTATT

Product: B12-dependent methionine synthase

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS [H]

Number of amino acids: Translated: 1246; Mature: 1245

Protein sequence:

>1246_residues
MATPVLSQATKALAQSRQQRLNEDLSTRILILDGAMGTMIQGHKLEEEHYRGSRFADWHCDVKGNNDLLVLTQPEIIKGI
HREYLLAGADIIETNTFNATTVAMADYDMQSLSAEINLVGARIAREVADEVEAQTGIPRYVAGVLGPTNRTCSISPDVND
PGYRNIHFDDLVTAYRESTAALIEGGADIIMVETIFDTLNAKAALFAIESIFDEVGLRLPVMISGTITDASGRTLTGQTT
EAFYNSLRHIKPISMGLNCALGPKELRPYVEELSRISECYVSAHPNAGLPNEFGGYDETPKEMADIIVQWAIEGMLNIVG
GCCGTTPDHIRVIREAVEKHAPRKLPELPVACRLAGLEPLTISADSLFVNVGERTNVTGSAKFLKLIKEGQYETALDVAR
DQVENGAQIIDINMDEGMLDGEEVMTTFLNLVASEPEISKVPIMIDSSKWEVIEAGLKCVQGKCIVNSISLKEGEAKFIE
QATLVKRYGAAAIIMAFDETGQADTRARKIEICTRAYRILVDKVGFPPEDIIFDPNIFAVATGIEEHDNYAVDFIEAVRD
IKATLPHAMISGGVSNVSFSFRGNNPVREAIHAVFLYHAIKEGMDMGIVNAGQLAIYDDIPAELKERVEAVVLNLPCPVE
DSTNTEQLLEIAEKYRGGGGSGAGKKEDLQWRSLPVNKRLEHALVKGITEFIDADTEEARQQATRPLDVIEGPLMDGMNV
VGDLFGEGKMFLPQVVKSARVMKKAVAYLNPFIEAEKVAGQSNGKVLMVTVKGDVHDIGKNIVGVVLACNGYEVIDLGVM
VPVEKIVEVAKKEQVDIIGMSGLITPSLDEMVHNVKTFEREGLTLPAIIGGATCSKIHTAVKIAPHYPHGAIYIPDASRA
VPMVSKLINEETRAATIKATYDEYDVMREKRLSQAKRKEIISIEAARENRCQLDWANYQPKVPNKLGIQVFEDYPLDDLV
DRIDWTPFFRAWELHGHFPRILEDEVVGEEARKLFADAKAMLQTIIDEKWLTAKGVIGLFPANTVNHDDIELYTDESRSQ
VLMTTHHLRMQIERVGNDNFCLSDFVAPKDSGVVDYTGGFAVCAGHGIDEHLARFEANHDDYNAIMLKVLADRLAEAFAE
RMHERVRKEFWGYASDENLDNEALIREKYRGIRPAPGYPACPDHTEKGLLWDLLKPNECIDLNITESFAMYPTAAVSGWY
FAHPEARYFGVTNIGRDQVEDYARRKGMTVAETEKWLAPILDYDPE

Sequences:

>Translated_1246_residues
MATPVLSQATKALAQSRQQRLNEDLSTRILILDGAMGTMIQGHKLEEEHYRGSRFADWHCDVKGNNDLLVLTQPEIIKGI
HREYLLAGADIIETNTFNATTVAMADYDMQSLSAEINLVGARIAREVADEVEAQTGIPRYVAGVLGPTNRTCSISPDVND
PGYRNIHFDDLVTAYRESTAALIEGGADIIMVETIFDTLNAKAALFAIESIFDEVGLRLPVMISGTITDASGRTLTGQTT
EAFYNSLRHIKPISMGLNCALGPKELRPYVEELSRISECYVSAHPNAGLPNEFGGYDETPKEMADIIVQWAIEGMLNIVG
GCCGTTPDHIRVIREAVEKHAPRKLPELPVACRLAGLEPLTISADSLFVNVGERTNVTGSAKFLKLIKEGQYETALDVAR
DQVENGAQIIDINMDEGMLDGEEVMTTFLNLVASEPEISKVPIMIDSSKWEVIEAGLKCVQGKCIVNSISLKEGEAKFIE
QATLVKRYGAAAIIMAFDETGQADTRARKIEICTRAYRILVDKVGFPPEDIIFDPNIFAVATGIEEHDNYAVDFIEAVRD
IKATLPHAMISGGVSNVSFSFRGNNPVREAIHAVFLYHAIKEGMDMGIVNAGQLAIYDDIPAELKERVEAVVLNLPCPVE
DSTNTEQLLEIAEKYRGGGGSGAGKKEDLQWRSLPVNKRLEHALVKGITEFIDADTEEARQQATRPLDVIEGPLMDGMNV
VGDLFGEGKMFLPQVVKSARVMKKAVAYLNPFIEAEKVAGQSNGKVLMVTVKGDVHDIGKNIVGVVLACNGYEVIDLGVM
VPVEKIVEVAKKEQVDIIGMSGLITPSLDEMVHNVKTFEREGLTLPAIIGGATCSKIHTAVKIAPHYPHGAIYIPDASRA
VPMVSKLINEETRAATIKATYDEYDVMREKRLSQAKRKEIISIEAARENRCQLDWANYQPKVPNKLGIQVFEDYPLDDLV
DRIDWTPFFRAWELHGHFPRILEDEVVGEEARKLFADAKAMLQTIIDEKWLTAKGVIGLFPANTVNHDDIELYTDESRSQ
VLMTTHHLRMQIERVGNDNFCLSDFVAPKDSGVVDYTGGFAVCAGHGIDEHLARFEANHDDYNAIMLKVLADRLAEAFAE
RMHERVRKEFWGYASDENLDNEALIREKYRGIRPAPGYPACPDHTEKGLLWDLLKPNECIDLNITESFAMYPTAAVSGWY
FAHPEARYFGVTNIGRDQVEDYARRKGMTVAETEKWLAPILDYDPE
>Mature_1245_residues
ATPVLSQATKALAQSRQQRLNEDLSTRILILDGAMGTMIQGHKLEEEHYRGSRFADWHCDVKGNNDLLVLTQPEIIKGIH
REYLLAGADIIETNTFNATTVAMADYDMQSLSAEINLVGARIAREVADEVEAQTGIPRYVAGVLGPTNRTCSISPDVNDP
GYRNIHFDDLVTAYRESTAALIEGGADIIMVETIFDTLNAKAALFAIESIFDEVGLRLPVMISGTITDASGRTLTGQTTE
AFYNSLRHIKPISMGLNCALGPKELRPYVEELSRISECYVSAHPNAGLPNEFGGYDETPKEMADIIVQWAIEGMLNIVGG
CCGTTPDHIRVIREAVEKHAPRKLPELPVACRLAGLEPLTISADSLFVNVGERTNVTGSAKFLKLIKEGQYETALDVARD
QVENGAQIIDINMDEGMLDGEEVMTTFLNLVASEPEISKVPIMIDSSKWEVIEAGLKCVQGKCIVNSISLKEGEAKFIEQ
ATLVKRYGAAAIIMAFDETGQADTRARKIEICTRAYRILVDKVGFPPEDIIFDPNIFAVATGIEEHDNYAVDFIEAVRDI
KATLPHAMISGGVSNVSFSFRGNNPVREAIHAVFLYHAIKEGMDMGIVNAGQLAIYDDIPAELKERVEAVVLNLPCPVED
STNTEQLLEIAEKYRGGGGSGAGKKEDLQWRSLPVNKRLEHALVKGITEFIDADTEEARQQATRPLDVIEGPLMDGMNVV
GDLFGEGKMFLPQVVKSARVMKKAVAYLNPFIEAEKVAGQSNGKVLMVTVKGDVHDIGKNIVGVVLACNGYEVIDLGVMV
PVEKIVEVAKKEQVDIIGMSGLITPSLDEMVHNVKTFEREGLTLPAIIGGATCSKIHTAVKIAPHYPHGAIYIPDASRAV
PMVSKLINEETRAATIKATYDEYDVMREKRLSQAKRKEIISIEAARENRCQLDWANYQPKVPNKLGIQVFEDYPLDDLVD
RIDWTPFFRAWELHGHFPRILEDEVVGEEARKLFADAKAMLQTIIDEKWLTAKGVIGLFPANTVNHDDIELYTDESRSQV
LMTTHHLRMQIERVGNDNFCLSDFVAPKDSGVVDYTGGFAVCAGHGIDEHLARFEANHDDYNAIMLKVLADRLAEAFAER
MHERVRKEFWGYASDENLDNEALIREKYRGIRPAPGYPACPDHTEKGLLWDLLKPNECIDLNITESFAMYPTAAVSGWYF
AHPEARYFGVTNIGRDQVEDYARRKGMTVAETEKWLAPILDYDPE

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

Organism=Homo sapiens, GI169790923, Length=1267, Percent_Identity=53.7490134175217, Blast_Score=1341, Evalue=0.0,
Organism=Escherichia coli, GI1790450, Length=1232, Percent_Identity=66.5584415584416, Blast_Score=1689, Evalue=0.0,
Organism=Escherichia coli, GI1786456, Length=320, Percent_Identity=24.375, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17535405, Length=1250, Percent_Identity=51.68, Blast_Score=1272, Evalue=0.0,
Organism=Drosophila melanogaster, GI20129603, Length=343, Percent_Identity=25.6559766763848, Blast_Score=69, Evalue=2e-11,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223 [H]

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]

EC number: =2.1.1.13 [H]

Molecular weight: Translated: 137872; Mature: 137741

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPVLSQATKALAQSRQQRLNEDLSTRILILDGAMGTMIQGHKLEEEHYRGSRFADWHC
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHCCCCCCHHHCCCCCCCCEEE
DVKGNNDLLVLTQPEIIKGIHREYLLAGADIIETNTFNATTVAMADYDMQSLSAEINLVG
EECCCCCEEEEECCHHHHHHHHHHHHHCCCEEECCCCCCEEEEEECCCHHHHHHHHHHHH
ARIAREVADEVEAQTGIPRYVAGVLGPTNRTCSISPDVNDPGYRNIHFDDLVTAYRESTA
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
ALIEGGADIIMVETIFDTLNAKAALFAIESIFDEVGLRLPVMISGTITDASGRTLTGQTT
HHHCCCCCEEEHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCCEECCCHH
EAFYNSLRHIKPISMGLNCALGPKELRPYVEELSRISECYVSAHPNAGLPNEFGGYDETP
HHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
KEMADIIVQWAIEGMLNIVGGCCGTTPDHIRVIREAVEKHAPRKLPELPVACRLAGLEPL
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHEECCCCCE
TISADSLFVNVGERTNVTGSAKFLKLIKEGQYETALDVARDQVENGAQIIDINMDEGMLD
EEECCEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCC
GEEVMTTFLNLVASEPEISKVPIMIDSSKWEVIEAGLKCVQGKCIVNSISLKEGEAKFIE
HHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHH
QATLVKRYGAAAIIMAFDETGQADTRARKIEICTRAYRILVDKVGFPPEDIIFDPNIFAV
HHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCEEEE
ATGIEEHDNYAVDFIEAVRDIKATLPHAMISGGVSNVSFSFRGNNPVREAIHAVFLYHAI
EECCHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHH
KEGMDMGIVNAGQLAIYDDIPAELKERVEAVVLNLPCPVEDSTNTEQLLEIAEKYRGGGG
HCCCCCCCCCCCCEEEECCCCHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHCCCCC
SGAGKKEDLQWRSLPVNKRLEHALVKGITEFIDADTEEARQQATRPLDVIEGPLMDGMNV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHCCCHHHHHHH
VGDLFGEGKMFLPQVVKSARVMKKAVAYLNPFIEAEKVAGQSNGKVLMVTVKGDVHDIGK
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHH
NIVGVVLACNGYEVIDLGVMVPVEKIVEVAKKEQVDIIGMSGLITPSLDEMVHNVKTFER
HHEEEEEEECCCEEEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHH
EGLTLPAIIGGATCSKIHTAVKIAPHYPHGAIYIPDASRAVPMVSKLINEETRAATIKAT
CCCEECHHCCCCHHHHHHHHEEECCCCCCCEEECCCCCCHHHHHHHHHCCCHHEEEEEEC
YDEYDVMREKRLSQAKRKEIISIEAARENRCQLDWANYQPKVPNKLGIQVFEDYPLDDLV
HHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCCCCCCCCCCEEECCCCHHHHH
DRIDWTPFFRAWELHGHFPRILEDEVVGEEARKLFADAKAMLQTIIDEKWLTAKGVIGLF
HHCCCCHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEC
PANTVNHDDIELYTDESRSQVLMTTHHLRMQIERVGNDNFCLSDFVAPKDSGVVDYTGGF
CCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEECCCE
AVCAGHGIDEHLARFEANHDDYNAIMLKVLADRLAEAFAERMHERVRKEFWGYASDENLD
EEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NEALIREKYRGIRPAPGYPACPDHTEKGLLWDLLKPNECIDLNITESFAMYPTAAVSGWY
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEECCCHHHCCHHHHCCEE
FAHPEARYFGVTNIGRDQVEDYARRKGMTVAETEKWLAPILDYDPE
EECCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ATPVLSQATKALAQSRQQRLNEDLSTRILILDGAMGTMIQGHKLEEEHYRGSRFADWHC
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHCCCCCCHHHCCCCCCCCEEE
DVKGNNDLLVLTQPEIIKGIHREYLLAGADIIETNTFNATTVAMADYDMQSLSAEINLVG
EECCCCCEEEEECCHHHHHHHHHHHHHCCCEEECCCCCCEEEEEECCCHHHHHHHHHHHH
ARIAREVADEVEAQTGIPRYVAGVLGPTNRTCSISPDVNDPGYRNIHFDDLVTAYRESTA
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
ALIEGGADIIMVETIFDTLNAKAALFAIESIFDEVGLRLPVMISGTITDASGRTLTGQTT
HHHCCCCCEEEHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCCEECCCHH
EAFYNSLRHIKPISMGLNCALGPKELRPYVEELSRISECYVSAHPNAGLPNEFGGYDETP
HHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
KEMADIIVQWAIEGMLNIVGGCCGTTPDHIRVIREAVEKHAPRKLPELPVACRLAGLEPL
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHEECCCCCE
TISADSLFVNVGERTNVTGSAKFLKLIKEGQYETALDVARDQVENGAQIIDINMDEGMLD
EEECCEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCC
GEEVMTTFLNLVASEPEISKVPIMIDSSKWEVIEAGLKCVQGKCIVNSISLKEGEAKFIE
HHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHH
QATLVKRYGAAAIIMAFDETGQADTRARKIEICTRAYRILVDKVGFPPEDIIFDPNIFAV
HHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCEEEE
ATGIEEHDNYAVDFIEAVRDIKATLPHAMISGGVSNVSFSFRGNNPVREAIHAVFLYHAI
EECCHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHH
KEGMDMGIVNAGQLAIYDDIPAELKERVEAVVLNLPCPVEDSTNTEQLLEIAEKYRGGGG
HCCCCCCCCCCCCEEEECCCCHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHCCCCC
SGAGKKEDLQWRSLPVNKRLEHALVKGITEFIDADTEEARQQATRPLDVIEGPLMDGMNV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHCCCHHHHHHH
VGDLFGEGKMFLPQVVKSARVMKKAVAYLNPFIEAEKVAGQSNGKVLMVTVKGDVHDIGK
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHH
NIVGVVLACNGYEVIDLGVMVPVEKIVEVAKKEQVDIIGMSGLITPSLDEMVHNVKTFER
HHEEEEEEECCCEEEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHH
EGLTLPAIIGGATCSKIHTAVKIAPHYPHGAIYIPDASRAVPMVSKLINEETRAATIKAT
CCCEECHHCCCCHHHHHHHHEEECCCCCCCEEECCCCCCHHHHHHHHHCCCHHEEEEEEC
YDEYDVMREKRLSQAKRKEIISIEAARENRCQLDWANYQPKVPNKLGIQVFEDYPLDDLV
HHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCCCCCCCCCCEEECCCCHHHHH
DRIDWTPFFRAWELHGHFPRILEDEVVGEEARKLFADAKAMLQTIIDEKWLTAKGVIGLF
HHCCCCHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEC
PANTVNHDDIELYTDESRSQVLMTTHHLRMQIERVGNDNFCLSDFVAPKDSGVVDYTGGF
CCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEECCCE
AVCAGHGIDEHLARFEANHDDYNAIMLKVLADRLAEAFAERMHERVRKEFWGYASDENLD
EEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NEALIREKYRGIRPAPGYPACPDHTEKGLLWDLLKPNECIDLNITESFAMYPTAAVSGWY
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEECCCHHHCCHHHHCCEE
FAHPEARYFGVTNIGRDQVEDYARRKGMTVAETEKWLAPILDYDPE
EECCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]