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The map label for this gene is pilE [H]

Identifier: 119773511

GI number: 119773511

Start: 447973

End: 448446

Strand: Reverse

Name: pilE [H]

Synonym: Sama_0370

Alternate gene names: 119773511

Gene position: 448446-447973 (Counterclockwise)

Preceding gene: 119773512

Following gene: 119773510

Centisome position: 10.41

GC content: 47.26

Gene sequence:

>474_bases
ATGAAAGGTATCAATTTTAAAAAGAACGCCAAGGGTTTCACCCTGATCGAACTGATGATCGTAGTAGCCATCATCGGTAT
CCTTGCCGCCATCGCGCTGCCTGCTTACAAAACTTACACTCAACGTGCAAAGTTCAGTGAAGTTGTTTTGGCAGCGACTC
CAGCAAAAACCGCTGTAGATGTTTGTGTTCAAACCGGTACTAGCTGTGACAATTTGCAAGAAGACTCTACTGGATGGGCG
GCAAGTAGCTTAGTAACCAGTGTATCCATTGATGCGCAAATGATAGATGACCCAGCGAATCCTGGTACACAGATTGTGGA
TCCTGCTGGCGTGATTATCATCACTGTGGAATCTGTGGGTAACCCAGTATTCACCGATGGTCCATACACTTACATTCTAA
CCGGCACGCCAAACGCCGGAGGCTCTATGGACTGGGCACCATCAGGTACCTGTAAAGCAGCTGGTTTGTGTTAA

Upstream 100 bases:

>100_bases
ACACGGGCTTACGGACAACAGTAAAGTTAATTTGCACAGAAGTTGGATAGCCACAACTGCGTGAGCGCCAACGACTAATT
AGCAATAAACGGAGAGAGAA

Downstream 100 bases:

>100_bases
CAGCGACGTAGCATTCTGGGGACATCAAGTCCCCAGTTCTTACTGGGTTAATAATGCCAACAACCGGCTTGCACTTAGGA
TTGTCGACGCTGTTTTTACG

Product: prepilin-type cleavage/methylation

Products: NA

Alternate protein names: Pilin [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MKGINFKKNAKGFTLIELMIVVAIIGILAAIALPAYKTYTQRAKFSEVVLAATPAKTAVDVCVQTGTSCDNLQEDSTGWA
ASSLVTSVSIDAQMIDDPANPGTQIVDPAGVIIITVESVGNPVFTDGPYTYILTGTPNAGGSMDWAPSGTCKAAGLC

Sequences:

>Translated_157_residues
MKGINFKKNAKGFTLIELMIVVAIIGILAAIALPAYKTYTQRAKFSEVVLAATPAKTAVDVCVQTGTSCDNLQEDSTGWA
ASSLVTSVSIDAQMIDDPANPGTQIVDPAGVIIITVESVGNPVFTDGPYTYILTGTPNAGGSMDWAPSGTCKAAGLC
>Mature_157_residues
MKGINFKKNAKGFTLIELMIVVAIIGILAAIALPAYKTYTQRAKFSEVVLAATPAKTAVDVCVQTGTSCDNLQEDSTGWA
ASSLVTSVSIDAQMIDDPANPGTQIVDPAGVIIITVESVGNPVFTDGPYTYILTGTPNAGGSMDWAPSGTCKAAGLC

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

Organism=Escherichia coli, GI1786297, Length=52, Percent_Identity=48.0769230769231, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 16202; Mature: 16202

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGINFKKNAKGFTLIELMIVVAIIGILAAIALPAYKTYTQRAKFSEVVLAATPAKTAVD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHH
VCVQTGTSCDNLQEDSTGWAASSLVTSVSIDAQMIDDPANPGTQIVDPAGVIIITVESVG
HHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCEEECCCCEEEEEEECCC
NPVFTDGPYTYILTGTPNAGGSMDWAPSGTCKAAGLC
CCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKGINFKKNAKGFTLIELMIVVAIIGILAAIALPAYKTYTQRAKFSEVVLAATPAKTAVD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHH
VCVQTGTSCDNLQEDSTGWAASSLVTSVSIDAQMIDDPANPGTQIVDPAGVIIITVESVG
HHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCEEECCCCEEEEEEECCC
NPVFTDGPYTYILTGTPNAGGSMDWAPSGTCKAAGLC
CCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919; 9515697 [H]