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The map label for this gene is sglT [H]

Identifier: 119773444

GI number: 119773444

Start: 367949

End: 369739

Strand: Direct

Name: sglT [H]

Synonym: Sama_0303

Alternate gene names: 119773444

Gene position: 367949-369739 (Clockwise)

Preceding gene: 119773443

Following gene: 119773445

Centisome position: 8.54

GC content: 57.17

Gene sequence:

>1791_bases
ATGACCCTGGCATGGGTGGATTTACTGGTTATAGGCGCGTATCTGCTGGGCACGTTGGGGCTTGGGGTTTATATCTCCCG
CCTTGCCAGCAGAGACATGAATGCCTACTTTCTGGCGGGTAAGGAAATCCCCTGGTGGGCGCTTGGGGTTTCCAACGCCT
CGGGCATGTTCGACATCGCGGGCACCATGTGGCTGGTGTCCATGTGTTTTGTTTACGGCCTGAAGAGTGCCTGGCTGCCC
TGGGTGTGGCCCATCTTCAATCAGGTATTCCTGATGGTTTACCTGTCGGTGTGGCTGCGCCGCTCCAACGTGATGACAGG
GGCCCAGTGGCTGCAGACCCGCTTTGGCAGTGGCAGGGGCGCCGAGTTGTGCCAGCTGGTGGTGGTGATATTTGCCATTG
TCAGCGCCATCGGCTTTATCGCCTATGCCTTTAAAGGCATTGGAAAATTCGCGGCCATTTTCTTCCCGTGGCAGCTCTCG
CCAGACACCTATGCCCTGATTATTTTTGCCGTTACCTGCCTGTATGTGATTAAGGGCGGCATGTATTCGGTGGTGTTTAC
CGAGGTGATGCAGTTTGTGATCATGACCATAGCCGCCGTGGCCGTGGGCCTGATTGCCATTAATCTGGTCACCCCGGAGC
AAATCAAGGCCGCCACCCCGGAGGGCTGGGATAACATCTGGTTTGGGTGGCAGCTCGATCTCAACTGGCAGGGACTGATT
GACAGCGTGAACGACAAGATTCGCGCCGACAGTCTGGAGCTGATTGGTCTGATGATCATGATGATGCTGTTCAAGGGCGT
GCTCTTTTCCATGGCGGGCCCTGTGCCCAACTACGATATGCAGCGCATTCTGGCGACCCGCTCCCCCAAGGAGGCGGCCA
AGATGAGCGGCCTGGTGTCTTTGGTGATGTTTTTCCCCCGTTACATGATGGTGGCCGGTCTTACTGTGCTGGCGCTGGTG
TATATGGGGCCGGAAATCCAGGCCCAGGGGGGCAGCTTCGACTTCGAGCAAATTCTGCCCTATGCCATCCATAACTTTGT
GCCCGTGGGCCTGACTGGGCTGCTGATAGCCGGTTTGCTGGCGGCTTTTATGTCGACCCTGGCGGCATCGCTCAATGCCG
CTCCCGTGTACTTTGTGAATGACATCTACAAGCGCTATTTCCGCCCGGATGCCGAGGAGAGAACCTACGTTAAGGTCAGC
TATCTGGTGTCTCTGGTGCTGGTGCTGATTGGCGTGGGTCTGGGGCTGATGCTCTCCAGCATCAACGAGATCATGCAGTG
GATCTTTGGTGCCCTCTTTGGCGGCTATGCCGCGGCCAATCTACTGAAGTGGCATTGGTGGCGCTTTAATGCCTATGGCT
ACTTCTGGGGCATGATGGCGGGCTTGCTGGCGTCCTTGTGTCTGCCACTCTTTATGCCGGGTACTCATCCGCTGTTTGCC
TTCCCGCTGCTGCTGGCGCTGAGTCTGGCCGGCTCTATCTTGGGGACGCTGGCGACCCGTCCTGAGCCGGACGAGGTGCT
GTGCGCCTTCTACCGTCAGGTACGCCCCTGGGGCTGCTGGGGGCCGGTGCATGACAAGGTCAAGGAAGCCGATCCCGGCT
TCGACGCGGATACACACCCACTGCGGGATATGGTCAATATTCTGGTCGGTATGGCCTGGCAAATCTGTTTGGTGGCCTTG
CCCATCTACCTGGTTATCCAGCAATGGACTCAGGTGTGGGTGGCACTGGCACTGGCGATACTGACATCCTGGTTCCTGAA
GAAAAACTGGTTGGATAAGTTGAAAGATTAA

Upstream 100 bases:

>100_bases
CAAAGTGCATCCACATTGCTTTACTGGGCATGGATGAGGATACCAAGGCGGCTCTGGTGAAGGGCATTCGCTGTCAATCC
CTGGTGCAGGAGGAAACCCA

Downstream 100 bases:

>100_bases
TGAAAACAATAACTCTGAAAGAGGGCGCCCTGTCCTTACCACGTCTGACACCCTTGTTGTTAACCCCAACGCTGTTGACC
TTCTCCTTACTCACGGCAGT

Product: Na+/solute symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 596; Mature: 595

Protein sequence:

>596_residues
MTLAWVDLLVIGAYLLGTLGLGVYISRLASRDMNAYFLAGKEIPWWALGVSNASGMFDIAGTMWLVSMCFVYGLKSAWLP
WVWPIFNQVFLMVYLSVWLRRSNVMTGAQWLQTRFGSGRGAELCQLVVVIFAIVSAIGFIAYAFKGIGKFAAIFFPWQLS
PDTYALIIFAVTCLYVIKGGMYSVVFTEVMQFVIMTIAAVAVGLIAINLVTPEQIKAATPEGWDNIWFGWQLDLNWQGLI
DSVNDKIRADSLELIGLMIMMMLFKGVLFSMAGPVPNYDMQRILATRSPKEAAKMSGLVSLVMFFPRYMMVAGLTVLALV
YMGPEIQAQGGSFDFEQILPYAIHNFVPVGLTGLLIAGLLAAFMSTLAASLNAAPVYFVNDIYKRYFRPDAEERTYVKVS
YLVSLVLVLIGVGLGLMLSSINEIMQWIFGALFGGYAAANLLKWHWWRFNAYGYFWGMMAGLLASLCLPLFMPGTHPLFA
FPLLLALSLAGSILGTLATRPEPDEVLCAFYRQVRPWGCWGPVHDKVKEADPGFDADTHPLRDMVNILVGMAWQICLVAL
PIYLVIQQWTQVWVALALAILTSWFLKKNWLDKLKD

Sequences:

>Translated_596_residues
MTLAWVDLLVIGAYLLGTLGLGVYISRLASRDMNAYFLAGKEIPWWALGVSNASGMFDIAGTMWLVSMCFVYGLKSAWLP
WVWPIFNQVFLMVYLSVWLRRSNVMTGAQWLQTRFGSGRGAELCQLVVVIFAIVSAIGFIAYAFKGIGKFAAIFFPWQLS
PDTYALIIFAVTCLYVIKGGMYSVVFTEVMQFVIMTIAAVAVGLIAINLVTPEQIKAATPEGWDNIWFGWQLDLNWQGLI
DSVNDKIRADSLELIGLMIMMMLFKGVLFSMAGPVPNYDMQRILATRSPKEAAKMSGLVSLVMFFPRYMMVAGLTVLALV
YMGPEIQAQGGSFDFEQILPYAIHNFVPVGLTGLLIAGLLAAFMSTLAASLNAAPVYFVNDIYKRYFRPDAEERTYVKVS
YLVSLVLVLIGVGLGLMLSSINEIMQWIFGALFGGYAAANLLKWHWWRFNAYGYFWGMMAGLLASLCLPLFMPGTHPLFA
FPLLLALSLAGSILGTLATRPEPDEVLCAFYRQVRPWGCWGPVHDKVKEADPGFDADTHPLRDMVNILVGMAWQICLVAL
PIYLVIQQWTQVWVALALAILTSWFLKKNWLDKLKD
>Mature_595_residues
TLAWVDLLVIGAYLLGTLGLGVYISRLASRDMNAYFLAGKEIPWWALGVSNASGMFDIAGTMWLVSMCFVYGLKSAWLPW
VWPIFNQVFLMVYLSVWLRRSNVMTGAQWLQTRFGSGRGAELCQLVVVIFAIVSAIGFIAYAFKGIGKFAAIFFPWQLSP
DTYALIIFAVTCLYVIKGGMYSVVFTEVMQFVIMTIAAVAVGLIAINLVTPEQIKAATPEGWDNIWFGWQLDLNWQGLID
SVNDKIRADSLELIGLMIMMMLFKGVLFSMAGPVPNYDMQRILATRSPKEAAKMSGLVSLVMFFPRYMMVAGLTVLALVY
MGPEIQAQGGSFDFEQILPYAIHNFVPVGLTGLLIAGLLAAFMSTLAASLNAAPVYFVNDIYKRYFRPDAEERTYVKVSY
LVSLVLVLIGVGLGLMLSSINEIMQWIFGALFGGYAAANLLKWHWWRFNAYGYFWGMMAGLLASLCLPLFMPGTHPLFAF
PLLLALSLAGSILGTLATRPEPDEVLCAFYRQVRPWGCWGPVHDKVKEADPGFDADTHPLRDMVNILVGMAWQICLVALP
IYLVIQQWTQVWVALALAILTSWFLKKNWLDKLKD

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI109659836, Length=553, Percent_Identity=25.497287522604, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI109659839, Length=569, Percent_Identity=24.2530755711775, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI14140236, Length=594, Percent_Identity=23.9057239057239, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI17941285, Length=494, Percent_Identity=25.5060728744939, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI4507033, Length=432, Percent_Identity=25.9259259259259, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4507031, Length=597, Percent_Identity=22.7805695142379, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI206597483, Length=562, Percent_Identity=25.2669039145907, Blast_Score=78, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 66449; Mature: 66318

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLAWVDLLVIGAYLLGTLGLGVYISRLASRDMNAYFLAGKEIPWWALGVSNASGMFDIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCHHHH
GTMWLVSMCFVYGLKSAWLPWVWPIFNQVFLMVYLSVWLRRSNVMTGAQWLQTRFGSGRG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
AELCQLVVVIFAIVSAIGFIAYAFKGIGKFAAIFFPWQLSPDTYALIIFAVTCLYVIKGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCC
MYSVVFTEVMQFVIMTIAAVAVGLIAINLVTPEQIKAATPEGWDNIWFGWQLDLNWQGLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCEEEEEEECCHHHHH
DSVNDKIRADSLELIGLMIMMMLFKGVLFSMAGPVPNYDMQRILATRSPKEAAKMSGLVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
LVMFFPRYMMVAGLTVLALVYMGPEIQAQGGSFDFEQILPYAIHNFVPVGLTGLLIAGLL
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFMSTLAASLNAAPVYFVNDIYKRYFRPDAEERTYVKVSYLVSLVLVLIGVGLGLMLSS
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
INEIMQWIFGALFGGYAAANLLKWHWWRFNAYGYFWGMMAGLLASLCLPLFMPGTHPLFA
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
FPLLLALSLAGSILGTLATRPEPDEVLCAFYRQVRPWGCWGPVHDKVKEADPGFDADTHP
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCHH
LRDMVNILVGMAWQICLVALPIYLVIQQWTQVWVALALAILTSWFLKKNWLDKLKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLAWVDLLVIGAYLLGTLGLGVYISRLASRDMNAYFLAGKEIPWWALGVSNASGMFDIA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]