Click here to switch to the map view.

The map label for this gene is yjjG [H]

Identifier: 119773426

GI number: 119773426

Start: 333460

End: 334149

Strand: Direct

Name: yjjG [H]

Synonym: Sama_0285

Alternate gene names: 119773426

Gene position: 333460-334149 (Clockwise)

Preceding gene: 119773425

Following gene: 119773427

Centisome position: 7.74

GC content: 57.39

Gene sequence:

>690_bases
ATGTCCAACTGCTCGCCGCTCAGCTTTGACTGGGTGTTATTTGATGCCGATGAAACCCTGTTTCATTTCGATGCCTTTGC
CGGACTCAAGCGCTTGTTCGCGCGCTTTGAGGTGGACTTCGGTGAGGCGCAATTCCACGAATACCAGCAGGTGAACAAGC
CCTTGTGGCTTGAGTATCAGGATGGTCGCATCAGTGCCAAAACCCTTCAGGAACAGCGGTTTGCCCTTTGGGGTGAGCGT
CTTGGGGTTGCTCCCGGTGAACTGAACTCCGGCTTTTTGCAGGCCATGGCCGACATCTGTGCGCCGCTGCCCCAGGTGCC
CGAACTGCTTGAGAGCCTTAAAGGCCGCTACCGCCTCGGCATCATCACCAACGGCTTTACCGAGCTGCAGCGCATTCGCC
TCGAACGCACCGGCTTTGCCGATCACTTTGAACTCTTGGTGATTTCTGAAGAAGTGGGCCTGGCCAAGCCCGATAAGGCC
ATTTTTGACCATGCCCTGGATGCCATGGGCAACCCGGCCCGTGAGCGGGTGCTGATGGTGGGCGATACCCTGTCCAGTGA
CATTCAGGGCGGCCTCAATGCCGGGCTGCACACCTGCTGGTATAACCCCAACGCCAAGGTTAACGAAGCGGGCATTTTGC
CGCATCTGGAGATTAGCTGTCACAGTGAGCTGGCTCGCTTATTGGCCTGA

Upstream 100 bases:

>100_bases
ACCCTGTGGAGCGGCGCTGATAATAGTCAGCACAACTTTTGCCACAGCCGCTTTGGGCGTACAATCGGCGGCCCTGATGC
CGTAATTAACAGGAAGTGAT

Downstream 100 bases:

>100_bases
ACGCCTTCCTTCGACTCCCGCCACGCCGCAGTGCTTTATCGCCTGCGGCGTTGTTTTTACGATGTTTTTCCCCCTTTCCC
TGATGTTGCTTTGTGTTCAG

Product: nucleotidase

Products: NA

Alternate protein names: House-cleaning nucleotidase; Non-canonical pyrimidine nucleotide phosphatase; Nucleoside 5'-monophosphate phosphohydrolase; dUMP phosphatase [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSNCSPLSFDWVLFDADETLFHFDAFAGLKRLFARFEVDFGEAQFHEYQQVNKPLWLEYQDGRISAKTLQEQRFALWGER
LGVAPGELNSGFLQAMADICAPLPQVPELLESLKGRYRLGIITNGFTELQRIRLERTGFADHFELLVISEEVGLAKPDKA
IFDHALDAMGNPARERVLMVGDTLSSDIQGGLNAGLHTCWYNPNAKVNEAGILPHLEISCHSELARLLA

Sequences:

>Translated_229_residues
MSNCSPLSFDWVLFDADETLFHFDAFAGLKRLFARFEVDFGEAQFHEYQQVNKPLWLEYQDGRISAKTLQEQRFALWGER
LGVAPGELNSGFLQAMADICAPLPQVPELLESLKGRYRLGIITNGFTELQRIRLERTGFADHFELLVISEEVGLAKPDKA
IFDHALDAMGNPARERVLMVGDTLSSDIQGGLNAGLHTCWYNPNAKVNEAGILPHLEISCHSELARLLA
>Mature_228_residues
SNCSPLSFDWVLFDADETLFHFDAFAGLKRLFARFEVDFGEAQFHEYQQVNKPLWLEYQDGRISAKTLQEQRFALWGERL
GVAPGELNSGFLQAMADICAPLPQVPELLESLKGRYRLGIITNGFTELQRIRLERTGFADHFELLVISEEVGLAKPDKAI
FDHALDAMGNPARERVLMVGDTLSSDIQGGLNAGLHTCWYNPNAKVNEAGILPHLEISCHSELARLLA

Specific function: Nucleotidase that shows high phosphatase activity toward non-canonical pyrimidine nucleotides and three canonical nucleoside 5'-monophosphates (UMP, dUMP, and dTMP), and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6- phosphogluconat

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. YjjG family [H]

Homologues:

Organism=Homo sapiens, GI23308749, Length=220, Percent_Identity=29.5454545454545, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1790833, Length=222, Percent_Identity=56.3063063063063, Blast_Score=269, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR011951 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 25678; Mature: 25546

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNCSPLSFDWVLFDADETLFHFDAFAGLKRLFARFEVDFGEAQFHEYQQVNKPLWLEYQ
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEC
DGRISAKTLQEQRFALWGERLGVAPGELNSGFLQAMADICAPLPQVPELLESLKGRYRLG
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEE
IITNGFTELQRIRLERTGFADHFELLVISEEVGLAKPDKAIFDHALDAMGNPARERVLMV
EEECCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHEEEEE
GDTLSSDIQGGLNAGLHTCWYNPNAKVNEAGILPHLEISCHSELARLLA
CCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEHHHHHHHHHHHC
>Mature Secondary Structure 
SNCSPLSFDWVLFDADETLFHFDAFAGLKRLFARFEVDFGEAQFHEYQQVNKPLWLEYQ
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEC
DGRISAKTLQEQRFALWGERLGVAPGELNSGFLQAMADICAPLPQVPELLESLKGRYRLG
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEE
IITNGFTELQRIRLERTGFADHFELLVISEEVGLAKPDKAIFDHALDAMGNPARERVLMV
EEECCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHEEEEE
GDTLSSDIQGGLNAGLHTCWYNPNAKVNEAGILPHLEISCHSELARLLA
CCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]