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The map label for this gene is argB

Identifier: 119773398

GI number: 119773398

Start: 295075

End: 295863

Strand: Direct

Name: argB

Synonym: Sama_0257

Alternate gene names: 119773398

Gene position: 295075-295863 (Clockwise)

Preceding gene: 119773397

Following gene: 119773399

Centisome position: 6.85

GC content: 56.53

Gene sequence:

>789_bases
ATGTCAGTAACTAACAAAGTATTGGTTCTCAAAGTGGGCGGCGCCCTGCTGCAGTGCGAAATGGGCATGGCCAGACTGAT
GGACACAGCCAGACAGCTGCTGGAAAAAGGCGAGCAGGTTGTGCTGGTGCACGGCGGCGGTTGTCTGGTTGACGAGCAGC
TCAAAGCCAATGGTATGGAGACGGTTAAGCTCGACGGTCTGCGGGTCACTCCGGCCGAGCAGATGCCCATTATCGCCGGT
GCGCTGGCGGGTACGTCCAACAAGTTGCTCCAGGGTGCGGCGGCCAAGGCCGGTGTGGTGAGCATGGGCATGAGCCTGTG
TGATGCCAACATGGTGACTGCGGTCATCAAAGACGAGCGCCTGGGCATGGTTGGTGAAGTGAGCCCCAAAGATGCCAAAG
CACTGGAATTTATTCTCGCTCAGGGCTGGCTGCCGATTATCAGTTCCATCGCCATGGGCGAAGACGGTGAGCTTTTGAAC
GTGAATGCCGACCAGGCAGCCTCAGTACTCGCCAAGCTCCTTGGCGGAAAACTGGTGTTGCTGTCTGACGTATCGGGCGT
GCTCGACGGTAAAGGCAAGTTAATCCCCAGTTTGAACAGCCAGGAGATAGATGAGCTGGTCAAACTGGGCGTGATAGAAA
AAGGCATGAAAGTCAAAGTAGAAGCAGCACTGGAAGTTGCCCAGTGGCTGGGACAACCGGTACAGGTTGCCTCGTGGCGT
GACAGCGGCCAAATGGCTGCGTTAATCAAGGGTGAGGCCGTGGGCACACAGATACAACCTCAGGAGTAA

Upstream 100 bases:

>100_bases
GGTGGTTGCCAGTGCCATCGACAATTTGATGAAGGGCGCTGCCAGTCAGGCACTTCAATGCATAAAAATTCATTTTGGCG
TTTAAGGCGGGAGCATCGGA

Downstream 100 bases:

>100_bases
TATATGAAGCATTTGATATCGATAAAAGAACTGACGCAAAAGCAGATGTTGGATCTGCTGACTCTGGCAAAGGAGATCAA
GGCCGACCCGGCCAAATACT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MSVTNKVLVLKVGGALLQCEMGMARLMDTARQLLEKGEQVVLVHGGGCLVDEQLKANGMETVKLDGLRVTPAEQMPIIAG
ALAGTSNKLLQGAAAKAGVVSMGMSLCDANMVTAVIKDERLGMVGEVSPKDAKALEFILAQGWLPIISSIAMGEDGELLN
VNADQAASVLAKLLGGKLVLLSDVSGVLDGKGKLIPSLNSQEIDELVKLGVIEKGMKVKVEAALEVAQWLGQPVQVASWR
DSGQMAALIKGEAVGTQIQPQE

Sequences:

>Translated_262_residues
MSVTNKVLVLKVGGALLQCEMGMARLMDTARQLLEKGEQVVLVHGGGCLVDEQLKANGMETVKLDGLRVTPAEQMPIIAG
ALAGTSNKLLQGAAAKAGVVSMGMSLCDANMVTAVIKDERLGMVGEVSPKDAKALEFILAQGWLPIISSIAMGEDGELLN
VNADQAASVLAKLLGGKLVLLSDVSGVLDGKGKLIPSLNSQEIDELVKLGVIEKGMKVKVEAALEVAQWLGQPVQVASWR
DSGQMAALIKGEAVGTQIQPQE
>Mature_261_residues
SVTNKVLVLKVGGALLQCEMGMARLMDTARQLLEKGEQVVLVHGGGCLVDEQLKANGMETVKLDGLRVTPAEQMPIIAGA
LAGTSNKLLQGAAAKAGVVSMGMSLCDANMVTAVIKDERLGMVGEVSPKDAKALEFILAQGWLPIISSIAMGEDGELLNV
NADQAASVLAKLLGGKLVLLSDVSGVLDGKGKLIPSLNSQEIDELVKLGVIEKGMKVKVEAALEVAQWLGQPVQVASWRD
SGQMAALIKGEAVGTQIQPQE

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=252, Percent_Identity=46.4285714285714, Blast_Score=205, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6320913, Length=257, Percent_Identity=27.6264591439689, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_SHEAM (A1S262)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_926138.1
- ProteinModelPortal:   A1S262
- SMR:   A1S262
- STRING:   A1S262
- GeneID:   4602513
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_0257
- NMPDR:   fig|326297.7.peg.247
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MVLCGST
- PhylomeDB:   A1S262
- ProtClustDB:   PRK00942
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 27333; Mature: 27201

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: BINDING 68-68 BINDING 160-160

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTNKVLVLKVGGALLQCEMGMARLMDTARQLLEKGEQVVLVHGGGCLVDEQLKANGME
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEECHHHHCCCCC
TVKLDGLRVTPAEQMPIIAGALAGTSNKLLQGAAAKAGVVSMGMSLCDANMVTAVIKDER
EEEECCEEECCHHCCCEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
LGMVGEVSPKDAKALEFILAQGWLPIISSIAMGEDGELLNVNADQAASVLAKLLGGKLVL
CCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCCEEE
LSDVSGVLDGKGKLIPSLNSQEIDELVKLGVIEKGMKVKVEAALEVAQWLGQPVQVASWR
EECCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCEEEEEEC
DSGQMAALIKGEAVGTQIQPQE
CCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SVTNKVLVLKVGGALLQCEMGMARLMDTARQLLEKGEQVVLVHGGGCLVDEQLKANGME
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEECHHHHCCCCC
TVKLDGLRVTPAEQMPIIAGALAGTSNKLLQGAAAKAGVVSMGMSLCDANMVTAVIKDER
EEEECCEEECCHHCCCEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
LGMVGEVSPKDAKALEFILAQGWLPIISSIAMGEDGELLNVNADQAASVLAKLLGGKLVL
CCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCCEEE
LSDVSGVLDGKGKLIPSLNSQEIDELVKLGVIEKGMKVKVEAALEVAQWLGQPVQVASWR
EECCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCEEEEEEC
DSGQMAALIKGEAVGTQIQPQE
CCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA