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The map label for this gene is pfp [H]

Identifier: 119717322

GI number: 119717322

Start: 3300835

End: 3302061

Strand: Reverse

Name: pfp [H]

Synonym: Noca_3098

Alternate gene names: 119717322

Gene position: 3302061-3300835 (Counterclockwise)

Preceding gene: 119717323

Following gene: 119717321

Centisome position: 66.23

GC content: 70.17

Gene sequence:

>1227_bases
ATGACCGTCCGCCGCGTTGCGCTGCTCACCGCCGGGGGCCTGGCCCCGTGCCTGTCCTCGGCCGTCGGAGCGCTGATCGA
GCGCTACACCGAGGTCGAGCCGGAGATCGAGATCATCGCCTACCTCAATGGGTACGCCGGGCTGCTCGGTGGCCGGTACC
TCACGATCACCCCGGAGGTGCGCGACCAGGCTCACCTGCTGCACCGGTACGGCGGCAGCCCGATCGGCAACAGCCGGGTC
AAGCTCACGAACGTCAAGGACTGCGTCAAGCGCGGCCTCGTCCAGGAGGGTCAGGACCCGCTGCACGTGGCGGCTGAGCA
GCTGACCAGGGACGGCGTCGACGTCCTGCACACCATCGGCGGGGACGACACGAACACGACCGCGGCCGACCTGGCGGCGT
ACCTCCACGAGAACGACTACGAGCTGACCGTCGTCGGCCTGCCCAAGACGATCGACAACGACGTGGTGCCGATCCGCCAG
TCGCTGGGTGCCTGGACCGCGGCCGAGCAGGGCGCGCTGTTCGCGCGCAACATCATCGCCGAGCACTCCTCGAACCCCCG
GATGCTGATCATCCACGAGGTGATGGGCCGCAACTGCGGCTGGCTGACCGCGGCGACCGCGGCGAAGTACCGCGAGTGGG
TCGTCGCCCAGGAGTTCTCCGGCTTCGGCGGCAACACCCAGGAGCACTGGGACGTGCACGCCGTCTACGTCCCCGAGCTG
TCCTTCGACATCGCCGCCGAGTCCGAGCGGCTCAAGGCCGTGATGGACCAGACCGGCTGCGTGAACATCTTCCTGTCCGA
GGGCGCCGGCGTCTCGACGATCGTCGAGGAGATGCTCGCGCGGGGCGAGGAGCCCAAGCGGGACGCGTTCGGCCACGTCA
AGCTGGACACGATCAACCCCGGCGCCTGGTTCGGCAAGCAGTTCGGCAAGCTCGTGGGCGCCGAGAAGACCATGGTGCAG
AAGAGCGGCTACTTCTCCCGCTCGGCGGCCGCCAACGACGAGGACCTCGCGCTGATCCGCGCCTGCTCCGACCTCGCCGT
CGACGCCGCCCTGCGCGGCGAGAGCGGTGTCGTCGGCCAGGACGAGGACGCCGACGGCGAGCTGCGGGTCTGCGAGTTCC
CGCGGATCCGCGGCGGCAAGGTGTTCGACACCTCCGCGCCGTGGTTCGGCGAGCTGCTGGCGGGCATCGGCCAGCCCACC
GGGGAGCCGGTGGCGGCCGACCACTGA

Upstream 100 bases:

>100_bases
GTGGCCGGGCAGGGTTAGGTCCGGCTAGAGTCGAAGTAGTGACTGTGAACGATCCAAAGGTGCCCGCCCCGGGGCCCCGA
GCAGAGAGAGCAGAAGCCCC

Downstream 100 bases:

>100_bases
CCCGGCCGGGCCACGACGCTCGGGAGACGCCGGGGGATTGAGGCCGGGTGCGGTGGGGGAACGATCCAGGAGATCCGACC
CCGACCGAGGAGAGCCCGAT

Product: pyrophosphate--fructose-6-phosphate 1-phosphotransferase

Products: NA

Alternate protein names: 6-phosphofructokinase, pyrophosphate dependent; PPi-dependent phosphofructokinase; PPi-PFK; Pyrophosphate-dependent 6-phosphofructose-1-kinase [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MTVRRVALLTAGGLAPCLSSAVGALIERYTEVEPEIEIIAYLNGYAGLLGGRYLTITPEVRDQAHLLHRYGGSPIGNSRV
KLTNVKDCVKRGLVQEGQDPLHVAAEQLTRDGVDVLHTIGGDDTNTTAADLAAYLHENDYELTVVGLPKTIDNDVVPIRQ
SLGAWTAAEQGALFARNIIAEHSSNPRMLIIHEVMGRNCGWLTAATAAKYREWVVAQEFSGFGGNTQEHWDVHAVYVPEL
SFDIAAESERLKAVMDQTGCVNIFLSEGAGVSTIVEEMLARGEEPKRDAFGHVKLDTINPGAWFGKQFGKLVGAEKTMVQ
KSGYFSRSAAANDEDLALIRACSDLAVDAALRGESGVVGQDEDADGELRVCEFPRIRGGKVFDTSAPWFGELLAGIGQPT
GEPVAADH

Sequences:

>Translated_408_residues
MTVRRVALLTAGGLAPCLSSAVGALIERYTEVEPEIEIIAYLNGYAGLLGGRYLTITPEVRDQAHLLHRYGGSPIGNSRV
KLTNVKDCVKRGLVQEGQDPLHVAAEQLTRDGVDVLHTIGGDDTNTTAADLAAYLHENDYELTVVGLPKTIDNDVVPIRQ
SLGAWTAAEQGALFARNIIAEHSSNPRMLIIHEVMGRNCGWLTAATAAKYREWVVAQEFSGFGGNTQEHWDVHAVYVPEL
SFDIAAESERLKAVMDQTGCVNIFLSEGAGVSTIVEEMLARGEEPKRDAFGHVKLDTINPGAWFGKQFGKLVGAEKTMVQ
KSGYFSRSAAANDEDLALIRACSDLAVDAALRGESGVVGQDEDADGELRVCEFPRIRGGKVFDTSAPWFGELLAGIGQPT
GEPVAADH
>Mature_407_residues
TVRRVALLTAGGLAPCLSSAVGALIERYTEVEPEIEIIAYLNGYAGLLGGRYLTITPEVRDQAHLLHRYGGSPIGNSRVK
LTNVKDCVKRGLVQEGQDPLHVAAEQLTRDGVDVLHTIGGDDTNTTAADLAAYLHENDYELTVVGLPKTIDNDVVPIRQS
LGAWTAAEQGALFARNIIAEHSSNPRMLIIHEVMGRNCGWLTAATAAKYREWVVAQEFSGFGGNTQEHWDVHAVYVPELS
FDIAAESERLKAVMDQTGCVNIFLSEGAGVSTIVEEMLARGEEPKRDAFGHVKLDTINPGAWFGKQFGKLVGAEKTMVQK
SGYFSRSAAANDEDLALIRACSDLAVDAALRGESGVVGQDEDADGELRVCEFPRIRGGKVFDTSAPWFGELLAGIGQPTG
EPVAADH

Specific function: Key control step of glycolysis. [C]

COG id: COG0205

COG function: function code G; 6-phosphofructokinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphofructokinase family. PFP subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790350, Length=217, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321679, Length=232, Percent_Identity=31.8965517241379, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: 3981 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 950 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022953
- InterPro:   IPR000023
- InterPro:   IPR011405 [H]

Pfam domain/function: PF00365 PFK [H]

EC number: =2.7.1.90 [H]

Molecular weight: Translated: 43928; Mature: 43797

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRRVALLTAGGLAPCLSSAVGALIERYTEVEPEIEIIAYLNGYAGLLGGRYLTITPEV
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHCCEEEEECCCH
RDQAHLLHRYGGSPIGNSRVKLTNVKDCVKRGLVQEGQDPLHVAAEQLTRDGVDVLHTIG
HHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCC
GDDTNTTAADLAAYLHENDYELTVVGLPKTIDNDVVPIRQSLGAWTAAEQGALFARNIIA
CCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHCCCCHHHHCCHHHHHHHHH
EHSSNPRMLIIHEVMGRNCGWLTAATAAKYREWVVAQEFSGFGGNTQEHWDVHAVYVPEL
HCCCCCCEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCC
SFDIAAESERLKAVMDQTGCVNIFLSEGAGVSTIVEEMLARGEEPKRDAFGHVKLDTINP
CEEECCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCC
GAWFGKQFGKLVGAEKTMVQKSGYFSRSAAANDEDLALIRACSDLAVDAALRGESGVVGQ
CHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
DEDADGELRVCEFPRIRGGKVFDTSAPWFGELLAGIGQPTGEPVAADH
CCCCCCCEEEECCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TVRRVALLTAGGLAPCLSSAVGALIERYTEVEPEIEIIAYLNGYAGLLGGRYLTITPEV
CCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHCCEEEEECCCH
RDQAHLLHRYGGSPIGNSRVKLTNVKDCVKRGLVQEGQDPLHVAAEQLTRDGVDVLHTIG
HHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCC
GDDTNTTAADLAAYLHENDYELTVVGLPKTIDNDVVPIRQSLGAWTAAEQGALFARNIIA
CCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHCCCCHHHHCCHHHHHHHHH
EHSSNPRMLIIHEVMGRNCGWLTAATAAKYREWVVAQEFSGFGGNTQEHWDVHAVYVPEL
HCCCCCCEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCC
SFDIAAESERLKAVMDQTGCVNIFLSEGAGVSTIVEEMLARGEEPKRDAFGHVKLDTINP
CEEECCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCC
GAWFGKQFGKLVGAEKTMVQKSGYFSRSAAANDEDLALIRACSDLAVDAALRGESGVVGQ
CHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
DEDADGELRVCEFPRIRGGKVFDTSAPWFGELLAGIGQPTGEPVAADH
CCCCCCCEEEECCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1653240; 1317210 [H]